avinza time release

[jacky]

I recently went on buprenorphine so I could take a break from kratom and tramadol, which I was building a tolerance to. I spent three weeks on around 4-7 milligrams of buprenorphine day. On the last three days of bup use I cut my dose down to 3 milligrams, taking only 2.5 milligrams on the last day. On the last night I was barely tired, though I had been up for around 20 hours, anxious perhaps about the next mornings dose of morphine sulfate.
I awoke at 8.30 am, slightly sweaty, and proceeded to crush all the contents of an avinza 120 milligram pill. I then cooked this up in 4 milliliters of water and sucked it up into an oral dosage syringe. The day before I had been shopping for various implements for pushing this drug into my rectum. I had been told that morphine sulfate and even morphine are not that bioavailable when taken orally. The best candidate for the job was a package of fleet glycerin disposable suppository bulbs that hold around 4 millitres of liquid per bulb, there is a depth shield around the bulb and about a 2/12 inch lubricated applicator tip, that to my dismay is not tapered. the applicator comes with a sheath/cap in place. I emptied out the glycerin and washed it once, replacing the contents with about 30 milligrams worth of M solution. without going into too much detail the bulb works ok, delivering a very small payload, but not all the solution can be pushed into the body cavity, and I found myself refilling the bulb via an infant ear cleaning bulb and reapplying this diluted solution two more times. the remaining morphine in the bulb couldnt have been more than 5 milligrams, which I diposed of.
15 minutes later i felt an alert, my mouth awash with saliva, and a heavy feeling in my arms and legs. I was half expecting to not feel anything, as my last dose of buprenorphine had only been some 14 hours ago. but there it was, slowly creeping up.
I then tried around 10 milligrams of this solution dripped into my nostril. BURNS worse than H, and instantly my sinus is inflamed and swollen on the left side that I dripped the solution in. It is still burning, but within 10 minutes it is obviously working. after a little while my sinus became saturated, and I finally had to blow my nose, which still didnt stop the burn. I really dont think I could tolerate snorting this solution day in and day out, I have snorted H on a daily basis, and the morphine sulfate hurts more and for longer.
Reading up on the avinza website, one reason for NOT IVing this formulation, beyond the obvious that a time release drug isnt meant to be iv'd is that the avinza pill contains talc. I remember hearing a few years ago why some medications with talc are bad to shoot. Apperantly on the west coast a large number of ritalin pills were diverted from approved use in the early 80's,some of the people who were chronically injecting this drug ended up in emergency rooms, and some died, from the effects of talc depositing in the lungs.
with approx 40 milligram of morphine sulfate running through my body I feel pretty damn good, despite the buprenorphine that most obviously is still in my system.