Propylhexadrine- a new stimulant

[Hammilton]

Hey, for the first time in, well, maybe ever, I feel like I found a drug that isn't discussed at all, and I'm bringing it up here for discussion. You may have heard of this drug, probably not, but it's unscheduled in the U.S. and schedule V I think in Canada.

Propylhexadrine is an analogue of methamphetamine, but because the phenyl group (as in 'phenyl'ethylamine") is replaced with a cyclohexyl group, it isn't an amphetamine or even a PEA. It still has pronounced stimulant qualities, including euphoria, which from most indications isn't present with ephedrine which is also an analogue of methamphetamine.

In the 50's, after Benzedrine (which is just racemic amphetamine) was removed from Benzedrine inhalers, Propylhexadrine was substituted and was the chemical soaked into the cotton. It is done this way to this day. A Benzedrex (Current brand name) inhaler contains a quarter gram of propylhexadrine.

This also spurred abusers, who noted that the amphetamine-free inhalers still had an amphetamine-like kick to them, did a little research and learned how to crystalize this propylhexadrine (PHI), thus preparing it for injection. Some of them developed brain problems very quickly doing this. Apparently, however, it is still quite safe in the other routes. I haven't seen anything confirming this, however, it was just one doc's opinion.

This might be a potential starting place for meth synthesis, but more to my hopes, it might be the beginning of a line of entirely new stimulants. I'm in the middle of finishing up a bunch of poetry for a publication, halfway through a song I'm collaborating with a guy before he goes back the warm states to work on an album and I might have to do some 'agenting' for my fiance's Photography

(everyone I know who's seen her work agree's that she's amazing, but she's incredibly unsure of herself creatively- after years of learning, practicing and perfecting the art she's still convinced "anyone can do exactly what I do, it's hardly frameable)

because she won't even try to get her work exhibited unless she can get her confidence up some.

I've got a lot to do before I can devote myself to the heavy research that scouring for modifications of PHI that've have been synthesized, tested on rodents, primates, seeing which ones have been tested on humans, what the effects were and then delving into the pharmacology of the interesting ones can really be a bitch. It's hard to a lot of that stuff now, too, because I rely heavily on university professors to guide me and a lot of them aren't checking their emails now.

If anyone is interested I can give you what i've gotten so far. Just start by studying the pharmacology of PHI, and looking at the articles about it and better, analogues of it. Start making a list of authors and their Universities. With good notes the emailing portion is relatively easy.

You can learn fascinating things. A good example is when I was researching a legal XXXXXX derivative with an XXXXXXX action. In the literatures, only XXXXXXX was reported, but the guy who did the research was able to tell me about a slight modification to that chemical produced psychedelic effects. I got tons of research to look through, tons of SSPS datafiles (If you don't have and know how to use SSPS start there). Unfortunately, as 99% of potential drugs end up, it just wasn't suited for human use. The toxicity was just way too high and no one is saying anything about it.

BTW- Please don't ask me for any information about it. I signed a bunch of non-disclosure sorts of things so all I can say is "Sorry, don't know what you're talking about." I can't say the family they were working with or what sort of effect they were looking for with the original chemical. I'm sorry. It's just too good of a resource to mess up.

Hammilton

[devilsdrug]

looks like uv already had some eh, hammilton sometimes i dont know what to make of u

[robojunkie]

It probably is a decent stimulant but it would be incredibly difficult to oxidize that saturated ring up to an aromatic. Better off with the tried and true methods.

[Hammilton]

Watcha mean DD? I had a therapist who told me that once while deriding me about self-medicating and wasting 'my gift' (She found about about my drug use on the day my IQ test came back. Bah)

hammilton

[insanesteveo]

so hammilton, what is the recommended dose? i dont feel like eating a piece of cotton, so would you have to actually use up the inhaler in one sitting? or would a couple puffs be enough for a stimulant naive person?

whats the high like?

[psychotiKK]

Originally Posted by insanesteveo

so hammilton, what is the recommended dose? i dont feel like eating a piece of cotton, so would you have to actually use up the inhaler in one sitting? or would a couple puffs be enough for a stimulant naive person?

whats the high like?

Just one benzedrex cotton (250mg I believe) is enough for an amphetamine-like high. It tastes horrible and you get sickening menthol burps.. propylhexedrine lasts along time and can definately effect your sleep. Euphoria and stimulation is present. This drug is easily the best OTC stimulant available.. hell it's even better then alot of prescription stimulants! I'm talking about mostly schedule IV stimulants. Amphetamines are much better, of course. The most common way of taking benzedrex/propylhexedrine is opening up the inhaler and eating the cotton in little peices. There are other ways, but there isn't much of a point. You can crystalize them like crystal meth, and even IV them like the OP said, but this is incredibly dangerous and idiotic. You will most likely die if you start IVing it. Also to the OP... propylhexedrine has been around and abused for A LONG TIME! In vicks inhalers, there is l-methamphetamine as the main ingredient. Too bad it's full of side effects and isn't worth trying. Propylhexedrine is definately worth a try.. many people enjoy it, but some absolutely hate it.

[insanesteveo]

thanks for that description. i was wondering since i dont EVER do stimulants, if i could just USE the inhaler as directed. since i doubt i would need the whole thing. im sure it wouldnt take that long to use up.

[AceBeans]

This stuff is pretty decent. I ate one 250 mg cotton and I am still feeling the effects about 3 hours later. Certainly nothing like an methamphetamine type of buzz but the amphetamine like high is present although just a bit less.

The only way I can desribe it is amphetamine like but not quite full blown out amphetamine high. Whoever said this is the best OTC stimulant is certainly right. I am also curious to see if maybe a half gram dose would increase the euphoria a bit.

I've done a bit of research on it and there are easy extraction methods but I don't see the point in it unless you were planning on shooting it and that would not be a good idea.

Here is the easy extraction method:

Propylhexedrine can be extracted from the cotton rods:
in a glass baking dish, place the cotton rod.
pour a teaspoon of HCl/Muriatic Acid on it and let it sit for a second.
pour 3 teaspoons of dH20 over this and let the liquid run down to the other side, squeeze the juice out of the cotton.
evaporate, and you should be left with yellow crystals.

I would be interested to see if anyone can come up with a way to turn this into amphetamine or maybe straight benzedrine. Not sure if this is possible but I am sure there is something that can be done with it. Overall it's a great stimulant, far and beyond anything else OTC and will give you that speed fix if thats what you are looking for.

[orangejuice]

has anyone tried 500 mgs? or 2 cottons. i am interested in this. maybe this might help me through the work day instead of stacker 2s

[AceBeans]

Originally Posted by orangejuice

has anyone tried 500 mgs? or 2 cottons. i am interested in this. maybe this might help me through the work day instead of stacker 2s

From what i've read a half gram dose will increase the euphoria a little bit but mostly just prolongs to experience. I can tell you that this would certainly be better than stackers.

[orangejuice]

sounds good enough for me. Ima get one tomorrow at CVS and report how my day went after 5. this might be useful to me.. thanks

BTW do i just swallow it or do i have to chew it lol

[AceBeans]

Just cut the cotton into four peices and swallow it, pretty easy to get down.

[kingdxm]

Cutting up the cotton wadding, soaking it in HCl acid for 10 minutes. Then squeeze the liquid out of the cotton and then throw away the cotton. Then add the propyl/HCl-acid liquid to a container with a lid, and then add non-polar solvent(naptha, Zippo lighter fluid, or something along those lines) to dissolve the menthol, lavender oil( about 10ml per inhaler ). Shake the 2 liquids together for 5 min. and then let the 2 layer seperate. Using an eye dropper, siphon off the top naptha layer and throw away. Then let the propyl/HCL-acid layer evaporate( a microwave at low power can speed this up, just make sure not to burn it ). You should end up with some decent crystals of propylhexedrine. Don't snort it though, unless you want to burn a hole in your nasal septum, capsule it up. I have taken 2 of these at a time and felt a pretty strong buzz, about 1/3 to 1/2 as potent as amphetamines. For something that is so easy to obtain it is actually pretty enjoyable, at least for me. And when combined with narcotics, it is heavenly.

[HeidiW]

this sounds like a crank recipe I found in an old Uncle Fester's book. J/K

[Paregoric Kid]

propylhexedrine is not new it replaced the real amphetamines in the benzedrex inhalers decades ago and it has been abused just as long. there are people who actually IV it from the cottons, not a good idea.
there are also inhalers that contain l-methamphetamine.