Enhancing Morphine Sulfate Instant Release?

[panthrax]

I always thought that I was a informed opiate user but when I found this site in Feb. of this year, I have met people far more knowledgeable than me which is why I ask so many questions here.

But anyhow, I was wondering if there are any techniques to enhance MSIR's with any means of administration other than anal (I believe I have that one covered, haha.)

Thanks again, guys.

[chemboy7]

Cimetidine (Tagament), Grapefruit Juice, Benzodiazepines, Diphenhydramine (Benadryl)/Dimenhydrinate (Dramamine), possibly DXM? If I was trying to get the most out of them I would probably just IV them though.

[panthrax]

Originally Posted by chemboy7

Cimetidine (Tagament), Grapefruit Juice, Benzodiazepines, Diphenhydramine (Benadryl)/Dimenhydrinate (Dramamine), possibly DXM? If I was trying to get the most out of them I would probably just IV them though.

Thanks for the reply but I already knew all of those, haha.

I IV my morphine anyhow. I was just seeing if there was anything I could do to it to make it more potent, or anything I could do in advance to injection to boost the effect.

[alowishus]

Originally Posted by panthrax

Thanks for the reply but I already knew all of those, haha.

I IV my morphine anyhow. I was just seeing if there was anything I could do to it to make it more potent, or anything I could do in advance to injection to boost the effect.

Wonder if a IV straight to the brain would do anything??????
5 bucks for anyone willing to give it a go.

[Levity]

Originally Posted by alowishus

Wonder if a IV straight to the brain would do anything??????
5 bucks for anyone willing to give it a go.

No, it really wouldn't aside from killing a few million of your brain cells at the injection site.

Any narcotic has to be metabolized into a chemical with the capacity of passing through the blood brain barrier (digestion), absorbed by mucus membranes which in turn permeate through the BBB (plugging, snorting), or deposited directly into a vein and transported northward (injection).

The brain's capillaries are so small, you'd end up injecting into white matter, not a blood vein or artery.

However, injecting directly into the spine or brainstem could produce interesting results; anyone up for mixing some dope with cerebral-sprinal fluid? (just kidding. please dont.)

[WarmCyanide]

Originally Posted by Levity

No, it really wouldn't aside from killing a few million of your brain cells at the injection site.

Any narcotic has to be metabolized into a chemical with the capacity of passing through the blood brain barrier (digestion), absorbed by mucus membranes which in turn permeate through the BBB (plugging, snorting), or deposited directly into a vein and transported northward (injection).

The brain's capillaries are so small, you'd end up injecting into white matter, not a blood vein or artery.

At least youd have street cred

[Zoops]

Originally Posted by Levity

No, it really wouldn't aside from killing a few million of your brain cells at the injection site.

Any narcotic has to be metabolized into a chemical with the capacity of passing through the blood brain barrier (digestion), absorbed by mucus membranes which in turn permeate through the BBB (plugging, snorting), or deposited directly into a vein and transported northward (injection).

The brain's capillaries are so small, you'd end up injecting into white matter, not a blood vein or artery.

However, injecting directly into the spine or brainstem could produce interesting results; anyone up for mixing some dope with cerebral-sprinal fluid? (just kidding. please dont.)

Wow, check out the brain on that one.

Hey, what you say is true for the most part. What I'd like to ask is this: What, pray tell, is morphine metabolized into before she is able to get into the CNS? Insofar as codeine and heroin, for example, are concerned, you have a good point. Codeine has very very low binding affinity for the moo (mu) opiate receptor by itself (although it's not totally devoid of the ability to bind to the receptor), what it is is that codeine is metablized into morphine when it's swallered. Heroin is similar, as everyone who's reading this prolly knows already, because it's metabolized into mono-acetyl M and just plain ol' M pretty quickly, within minutes of ingestion, by whichever means. But morphine?

To answer the initial question of the thread - my answer is: TAKE A LARGER DOSE. (if u want an enhanced eperience).

[panthrax]

Well I am already IVing like 90mg with little effect...

Go for more?

[superman]

"Well I am already IVing like 90mg with little effect...

Go for more?"

take a break man. it's something all of us have to do in order to keep the euphoria at a nice level. and the tagaments or whatever they are will work, as will white GF juice

[vanilla_mlkshake2007]

Originally Posted by panthrax

Well I am already IVing like 90mg with little effect...

Go for more?

I was iv'ng 120 at once every day and then I split an avinza in half one day crushed up the balls really good added a bit of water and heated (so very lil just like warmed it) the spoon didn't even turn black .I held lighter there for less then 10 seconds as I hate it when it gets gooey.I'll tell you what this makes my dope at last 10-15 times more potent and I only have to continue using the same amount I was.In fact I did it today and I've been high to the point of almost vomiting not quite though.I know won't sleep all night as I have the best opiate buzz since Two sundays ago when I did the same thing.I do the morphine thing every day .Its just that I never realized how much that lil warm up increased the potency.If you heat it to much in my opinion It burns al the good stuff away,but I couldn't believe the actual difference!I only had to do 60 milligrams and even that was alot my dope will last much longer now.

[halfalien_s4]

heres some other meds in just in case u didnt know....reglan (metaclopromamide), phenagran (promethazine), compozine (prochlorpromozine), and visteraril (vistaril pam), other than that, parachuting while snorting or plugging is the only thing i can think of at the moment. if i think of anything else, ill post it....

[ShaneFlipside]

All this talk about using stomach meds to potentiate opiates gets me queasy - I've always refrained from taking heartburn meds, even when I had acid reflux for awhile - cuz like laxatives or most any palliative prep - one gets a tolerance and ends up needing the shit and getting the side effects etc etc - In other words, I love dope but hate medications haha. seriously though, is it really worth it. This has to do with morphine not being metabolized quick enough - but with grapefriuiut juice or with antacids one can cause it to break down before being pissed out. Am I on track? Now on a related question, what is the differenc between the MSContins and the Kadians - both are morphine sulphate, right?? And both are theoretically some type of sustained release. Does that mean they won't piss out quickly - do you get more of the morph by letting 'em dissolve at thier own speed so you don't piss half of it out - just taking more to bump up euphoria. What does everyone think?