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Old 11-21-2009, 10:52 AM   #1
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Default False positives

Well I couldn't find too much information with various Google searches and I'm curious: what can cause false positives on a "standard" drug test (marijuana/opiates/benzos/barbs/alcohol/pcp/cocaine)? By this I mean are there legal "dietary supplements" that would flag for one of these? Anyone have any experience with a false positive they can attribute to something legal they took? I have heard that ibeuprofin can cause a false for marijuana. I ask mainly so I can avoid these things, but also out of curiosity.
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Old 11-21-2009, 10:55 AM   #2
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Default Re: False positives

ephedrine - amphetamine
dxm - amphetamine or pcp
nyquil - alcohol (i know)
ibuprofen - marijuana (like u said)
poppy seeds - opiates
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Old 11-21-2009, 11:09 AM   #3
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Default Re: False positives

^^ Agree ^^

Don't think that by switching to making tea from a kilo of poppyseeds will clear your opi panel though.

The makers of most tests will allow a certain amount of morphine/codeine metabolites to "clear" their tests. This will cover the incidental poppyseed bagel, PS-bread, etc..., etc....

Some people say it would take ~100 PS bagels eaten over ~2days to show up positive on the average UA Opi panel. I'd reduce that by 50% to stay on the safer side. Avoiding them altogether would be safest of all.

You prolly already know this, I just started a new job with frequent UAs, so it is news to me.

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Old 11-21-2009, 11:16 AM   #4
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Default Re: False positives

I remember watching a Myth Busters episode on poppy-seed bagels. Both guys tested positive for opiates after eating poppy bagels and cake. http://www.mythbustersfanclub.com/mb...nt/view/15/27/
The one guy was nodding out HARD after eating the cake. (jk)
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Old 11-21-2009, 12:08 PM   #5
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Default Re: False positives

had dxm come up as methadone at the clinic. unless it got in my tar somehow. unlikely.
assholes wouldnt dose me.
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Old 11-21-2009, 12:20 PM   #6
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Default Re: False positives

Re: Mythbusters and poppy seeds:

"Adam finally gets answers when he calls a company in Europe that confirmed that the test can detect 300 to 1,200 nano grams (that’s one-billionth of a gram) of codeine."

I'd call that pretty sensitive.



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Old 11-21-2009, 12:26 PM   #7
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Default Re: False positives

if this be for practical reasons I'd advise SWIY to have
a glance at either the drug testing kit itself/ the chart
your doc uses to log the weekly data provided we'r
discussing testing at MMT clinic.

in fact such questions would not get a raised eyebrow
from a doc even IMO so SWIM needn't enter the picture
as what you would like to know is a valid medical concern,
something which could potentially screw up test results.

the common 'cheap' teststrips I see around although varry
(in fact my clinic recently updated making it more difficult
to cheat with methadone now testing metabolites not strait
up 'done) are not sensitive enough to pick up morphine w/in
poppy seeds. One has to take substantial dose of opiates
3-4 days prior to the test tops. 1/2 of my usual dose is gone
w/o a trace in 2-3 days even.

I will get the name of the kit they use if you guys interested.
It tests for methadone,morphine,oxycodone,cocaine,benzos
possibly amphetamines. I take the odd peek at the secretaries
scribbles in that "dirty" chart

so many obvious diehard lifer type junkies are all clean - ye right!
cheaters..
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Old 11-21-2009, 12:28 PM   #8
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Default Re: False positives

Quote:
Originally Posted by doctor diesel View Post
Re: Mythbusters and poppy seeds:

"Adam finally gets answers when he calls a company in Europe that confirmed that the test can detect 300 to 1,200 nano grams (that’s one-billionth of a gram) of codeine."

I'd call that pretty sensitive.



Doc

These tests ARE that sensitive !! But most makers will allow a certain amount (small amount) to show as "Negative" for incidental use.

I don't know the process, but maybe the cut-off point is 350ng to 400ng. If this is used by GC or MS, they will dectect them without problem. Usually to get to GC or MS, the urine sample has to FAIL the antibody dipstick. Depending on the company, they may not show positive until the threshold has been exceeded.

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Old 11-21-2009, 03:54 PM   #9
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Default Re: False positives

being on methadone for........guys, i really don't know anymore. figure at least 6 or 7 years?

anyways, in this time, i've had to do a bare minimum of 3 pee tests every 2 months - i've never had a false positive in that i was punished in some way.

i've only been question'd twice - i'd taken a bunch of gravol (dramamine in american) on the weekend - never having dirty urines they gave me the benefit of the doubt and ask'd, specifically, if i'd taken gravol, and how much....and apparently benadryl can throw the test off for amps or something? but not to the point where a speed freak can tweek day in/out and claim it's allergy medication.

after that, whatever i take between tests, i mention it while handing the cup back, never had anything of the sort happen again.

i've bugged them, *how do you know?*, they just smile, and say the differences between things that'll cause false positives and actual failures are significant enough to where it doesn't happen........based off how i understand drug tests to work/read -i think they're full of shit, and use the persons history, and current state of being, to decide if they're lying or not.
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Old 11-21-2009, 08:43 PM   #10
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Default Re: False positives

a good link is passmydrugtest.com for all the parameters...

false negatives are a crunt too--- got one after dosing a mere 10 hours pre-test with vics---the thing is, pain EATS opies, so an assload of pain is gonna rip thru a mere vic in nanoseconds...

do they account for THAT fact?! fuuuuuuuck NO!!!
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Old 11-21-2009, 10:13 PM   #11
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Default Re: False positives

http://www.drugsmartcup.com/products.htm

This is the drug test that they used when I was in rehab. It is a ten panel test which tests for THC, Opiates (Heroin/Codeine/Morphine), Oxycodone (Oxymorphone/Hydrocodone/Hydromorphone), Propoxyphene (Darvocet, don't know why this was on there), Amphetamines, Methamphetamine, MDMA, Cocaine, Benzos and Barbiturates.

Here is some info from the site that manufactured them:

Quote:
Multi Drug Screening Test (Urine)
Single and multi drug screen test cups for any
combination of the following drugs:

AMP/BAR/BZO/COC/THC/MTD/mAMP/MDMA/MOP/OPI/PCP/TCA
(Catalog. No. Varies on Configuration)

A rapid, one step screening test for the simultaneous, qualitative detection
of multiple drugs and drug metabolites in human urine.

For healthcare professionals including professionals at point of care sites.
For in vitro diagnostic use only.

INTENDED USE
The DrugSmartCupis a lateral flow chromatographic
immunoassay for the qualitative detection of multiple drugs and drug metabolites
in urine at the following cut-off concentrations:

Test Calibrator Cut-off

Amphetamine (AMP) D-Amphetamine 1,000 ng/mL
Barbiturates (BAR) Secobarbital 300 ng/mL
Benzodiazepines (BZO) Oxazepam 300 ng/mL
Cocaine (COC) Benzoylecgonine 300 ng/mL
Marijuana (THC) 11-nor-_9-THC-9 COOH 50 ng/mL
Methadone (MTD) Methadone 300 ng/mL
Methamphetamine (mAMP) D-Methamphetamine 1,000 ng/mL
Methylenedioxymethamphetamine
(MDMA) Ecstasy D,L Methylenedioxymethamphetamine 500 ng/mL
Morphine (MOP 300) Morphine 300 ng/mL
Opiates (OPI 2000) Morphine 2,000 ng/mL
Phencyclidine (PCP) Phencyclidine 25 ng/mL
Tricyclic Antidepressants (TCA) Nortriptyline 1,000 ng/mL

Configurations of the DrugSmartCup can consist of
any combination of the above listed drug analytes. This assay provides
only a preliminary analytical test result. A more specific alternate chemical
method must be used in order to obtain a confirmed analytical result. Gas
chromatography/mass spectrometry (GC/MS) is the preferred confirmatory
method. Clinical consideration and professional judgment should be
applied to any drug of abuse test result, particularly when preliminary
positive results are indicated.

BACKGROUND
Summary and Explanation of Test
The DrugSmartCupis a rapid urine screening test that can be
performed without the use of an instrument. The test utilizes monoclonal
antibodies to selectively detect elevated levels of specific drugs in urine.

Specimen Collection and Preparation
Urine Assay
The urine specimen must be collected in the DrugSmartCup. Urine
collected at any time of the day may be used. Urine specimens exhibiting visible
precipitates should be centrifuged, filtered, or allowed to settle to obtain a clear
specimen for testing.
Specimen Storage
Urine specimens may be stored at 2-8°C for up to 48 hours prior to testing. For
prolonged storage, specimens may be frozen and stored below -20°C. Frozen
specimens should be thawed and mixed well before testing.
Here is an excellent PDF file from the same site, listing a TON of different things that could cause false positives.

Clicky: http://www.drugsmartcup.com/Reaction.pdf
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Old 11-22-2009, 08:07 AM   #12
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Default Re: False positives

You are right...pain eats thru opioids. But, most of these test test for metabolites of the drug so the more you take the more metabolites will show up and therefore a pos.

But, all the dip tests are different and some have low (300) thresholds and some are high(1000). All depends which test they are useing. And remember, dips are for screening only and the results are to be confirmed by gas chromatography etc. So, if you are + or - and really think the dip is wrong ask to have it sent off for confirmation.
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Old 11-22-2009, 06:08 PM   #13
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Default Re: False positives

doc--- i'm so glad to see you here...

i'm looking forward to hearing more from you---

i'm a noobie too, but i'd like to welcome you in, and also to thank you very much for your time ---

you'll be reading stuff that will no doubt curl your toes, but any efforts towards harm reduction i'm sure will be very much appreciated---

if you don't mind me asking, how'd you find your way here?

again, welcome, and take good care...
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Old 11-23-2009, 03:19 PM   #14
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Default Re: False positives

Thanks for the welcome. Actually I was just googling one day and landed here. My CP practice IS opioids so I need to know all I can so I can better understand the opiated mind> I mean, no one ever started out to get addicted but the drugs can capture ANYONE. I also do addiction med with suboxone so I see people from all walks of life and I think the more I know the more I can help. My toes did not curl but my heart did hurt to see the pain these drugs can cause.
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Old 11-23-2009, 03:38 PM   #15
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Default Re: False positives

Wow drmom, You're a PM specialist, Addiction specialist with Bupe/Sub certification, you compound you own meds (as opposed to using a Registered Pharmacist) and you also see patients in hospital and hospice care. I'm surprised you even have any spare time during the day or early evening to post here.

You have a lot of energy - that's for sure.
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