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Codeine Topics relating to the chemistry, pharmacology, synthesis, method, or extraction of Codeine.

 
 
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Old 01-07-2009, 06:48 PM   #1
bigfootlives
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Default Why is codeine's solubility higher in cold water!

I'm sure most of you are familiar with this solubility chart that's found on nearly every CWE tutorial:

Solubility
| 31C water | 21C water
Aspirin | 1g / 100 ml | 1g / 300 ml
Acetaminophen | 1g / 70 ml | 1g / 150 ml
Codeine | 1g / 2.3 ml | 1g / 0.7 ml


Has anyone else ever wondered why it states that codeine is more soluble in cold water than hot water? Surely this must be a mistake, or does codeine phosphate's chemistry somehow "magically" make it more soluble in cold water than hot.
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