IVing 100mg retard granulate

[bogumil]

Imagine, SWIM is sitting there with the folleing items:

• MST 100 Retard-Granulate

Containing: 1.943g granulate with
- 100mg morphinesulfate 5H2O in form of:
morphine-poly(styrole-codivinylbenzol)sulfonate.

made for drinking after suspending in water.

• a 25mm syringe filter 0.2 ym Supor membrane, sterile for injection
• a junky-shotgun 2ml 26G x 1/2"

Here is a pic of the stuff:


SWIM thinks that the granulate isnt injectable cause it is "retarded" (haha) (Retard-Granulate)

So is there a chance to get this into SWIMS veins or muscles? SWIMS hope is the syringe filter but then again, the stuff isnt plain morphine sulfate but this strange morphine-polystyrole ... So SWIM is not going to IV this until he knows what it is. So hes hoping for some people who know about this, to tell him what to do...

Maybe you can help me out. Would be very great. ...

Edited: I googled and found, that this stuff is morphine sulfate bound to polysterole to make it slow release. It lasts 12 hours when one drinks the granulate dissolved in water. So definately a good thing for pain patients (who reported a better pain management and pain of only 3 points, compared to 7-10 points before treatment with mst retard-granulate on a scale of 10).
But a bad thing for injection I would say. Oh well. SWIM will probably take the chance to stop using H for a while and take the slow release instead. Maybe lowers tolerance.

Im wondering if it would help to imitate the ingestion? Like, letting it rest for 20 hours in a solution of very slightly acidic water? The water with HCl would do the same as the acid in the stomach ... the morphine would slowly go over from the polystyrole-complex into the aqueous with acid, bind to the acid and the polystyrole would sink to the bottom ... then SWIM could decant, filter the liquid with 0.2 ym and dry it. Should yield morphine-HCl, or?

[Mokelly]

Im wondering if it would help to imitate the ingestion? Like, letting it rest for 20 hours in a solution of very slightly acidic water? The water with HCl would do the same as the acid in the stomach ... the morphine would slowly go over from the polystyrole-complex into the aqueous with acid, bind to the acid and the polystyrole would sink to the bottom ... then SWIM could decant, filter the liquid with 0.2 ym and dry it. Should yield morphine-HCl, or?


I think that's a great Idea man, I'm not so sure what it would yield, but I think it would probably break the time release

[bogumil]

i would hope so. The drug has to leave the complex anyway to be useful for the body, so why not try to do this in vitro? A stomach-like millieu should help breaking up the complex. And when the pills need 12 hours until all the morphine is released, then the 20 hours should be fine. MAybe one has to adjust slightly heat, like 38 Celsius?

SWIM will try this. He told me he put the content of a capsule (also with a slow release complex) and put all the little balls into 5ml water with HCl. Hell wait a day and then filter, dry and messure. If there are aproximately 100mg final product then it should have worked, or? The one can try to redissolve it in water and see if it works ...

[Mokelly]

pm on the way bog

[exitwound]

Not really sure why you wouldn't just toss em back orally! I know injected morphine is a lot more efficient than oral, but with the retardant granules and such I'd figure it would be fairly difficult to get a clean injectable solution from the stuff.....

Then again, I don't know shit about injectability so there you go

[bogumil]

Yeah thats what SWIM will probably do. If it would have been just to dissolve it in water, suck it up the syringe and shoot, then of course he would have ived, but when there is so much work...