Ok, I know this is not something people will readily discuss or talk about... but some of you have guts/balls on here, so wtf, here goes nothing...
For the prudes among us, we all know there's smoking, IV, IM, oral, intranasal and plugging means intrarectal.
Now, I've heard that the bioactivity of pills in tablet form actually is not that efficient. Let's say you take a 5/325 perc, your body only absorbs 60-70% of the content e.g. 3.3-3.5 mg of the oxycodone. Now, that same dose administered rectally through a syringe let's say... the bioactivity jumps up to >= 90%.
My question: is there truth to this? If one were to crush up a pill, suck it into a syringe, stick it where the sun don't shine and let 'er rip would you actually get more of a buzz than just swollowing the pill "as is" or what have you?
It would stand to reason that the membranes in that area might be better suited to absorbing more of the material especially if it's already dissolved in water. Maybe this only works well for certain pill types and not others???
I know curiosity killed the cat but what the heck, I could not think of a better place to ask this question!