Advertise on Opiophile

+ Reply to Thread
Results 1 to 10 of 10

Thread: Fewest Carbons (lowest MW?) for opioid

  1. 05-05-2012 03:25 PM #1
    borohydride
    borohydride is offline
    OpioNoMo borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker
    Join Date
    May 2007
    Location
    UK
    Posts
    3,411

    Default Fewest Carbons (lowest MW?) for opioid

    It's always been a competition (seemingly) amongst designers of opioids to see how few carbon atoms they could use in their structure. The common target was usually M potency. I remember that they made quite a big thing about tapentadol over this.

    Tapentadol C14H23NO
    Ketobemidone C15H21NO2
    Nortilidine C16H21NO2
    Prodine C16H23NO2
    Morphine [b]C17[/b[H19NO3
    Fentanyl C22H28N2O

    I hope you see what I'm getting at. Carbon is the scaffold of organic drugs so the fewer Cs, the lower the complexity. It doesn't follow that it means that it's the simpler to make, but it does mean simpler final complexity.

    I'm not getting into the subjective (side)effects such as with tapentandol (in particular) but I've not seen a simpler 'morphine range' opioid with 14 carbons before and I doubt it's possible... but I would like to be proved wrong...
    Reply With Quote Reply With Quote
  2. 05-05-2012 03:50 PM #2
    doctor diesel
    doctor diesel is offline
    Never Looked Back doctor diesel has disabled reputation doctor diesel's Avatar
    Join Date
    Feb 2005
    Posts
    4,140

    Default Re: Fewest Carbons (lowest MW?) for opioid

    UK weather's darned cold for the time of year, dontcha think?
    TOP JUNK FROM TOP JUNKIES
    PAUPS "A long, narrow foot usually matches a long, narrow face, while stubby toes usually belong to beady eyes"
    DAK "People are worried I'll get so skinny I fall through my asshole and hang myself"
    CHOPS "You gotta be pretty smart to know you're stupid"
    JAMESDIGITS "I've seen horrible people in clinics and had to wait outside due to the stench"
    MAKITA "It wasn't MRSA and it wasn't necrotic fasciitis, it was just some fucked-up shit*"
    *Medical term
    Reply With Quote Reply With Quote
  3. 05-05-2012 03:56 PM #3
    borohydride
    borohydride is offline
    OpioNoMo borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker
    Join Date
    May 2007
    Location
    UK
    Posts
    3,411

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Quote Originally Posted by doctor diesel View Post
    UK weather's darned cold for the time of year, dontcha think?
    +100 - only 1 C in CO2... and non in H2O!
    Reply With Quote Reply With Quote
  4. 05-05-2012 03:58 PM #4
    doctor diesel
    doctor diesel is offline
    Never Looked Back doctor diesel has disabled reputation doctor diesel's Avatar
    Join Date
    Feb 2005
    Posts
    4,140

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Well fuck me backwards.
    TOP JUNK FROM TOP JUNKIES
    PAUPS "A long, narrow foot usually matches a long, narrow face, while stubby toes usually belong to beady eyes"
    DAK "People are worried I'll get so skinny I fall through my asshole and hang myself"
    CHOPS "You gotta be pretty smart to know you're stupid"
    JAMESDIGITS "I've seen horrible people in clinics and had to wait outside due to the stench"
    MAKITA "It wasn't MRSA and it wasn't necrotic fasciitis, it was just some fucked-up shit*"
    *Medical term
    Reply With Quote Reply With Quote
  5. 05-05-2012 04:02 PM #5
    borohydride
    borohydride is offline
    OpioNoMo borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker
    Join Date
    May 2007
    Location
    UK
    Posts
    3,411

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Quote Originally Posted by doctor diesel View Post
    Well fuck me backwards.
    But we haven't been formally introduced, even.... no matter - grease me up man, I'm going in!!!
    Reply With Quote Reply With Quote
  6. 05-05-2012 05:00 PM #6
    chopstix
    chopstix is online now
    True Opiophile chopstix has disabled reputation chopstix's Avatar
    Join Date
    Feb 2007
    Location
    rabbit hole
    Posts
    8,448

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Sweet!! ANOTHER junky couple spawned from opiophile. <3<3<3

    Hey Jonny - maybe you could turn this into a junkie dating service??
    All posts made under the user account 'Chopstix' are simple exercises of creative fiction, and in no way represent or should be interpreted as fact or truth, nor as anything more than simple entertainment. The user account 'Chopstix' is an account open to multiple authors for the purpose of exercising a common interest in specific topics of creative fiction, and in no way is any single user responsible for the entirety of the post content of this account.
    All content posted under the user account 'Chopstix' is the property of the original post author, and is not to be copied or reproduced in any fashion without expressed written and notarized permission of the original author. Violation of copy-write, unless otherwise granted, is expressly prohibited.

    ..so don't fuck up and do the right thing..
    Reply With Quote Reply With Quote
  7. 05-05-2012 05:06 PM #7
    borohydride
    borohydride is offline
    OpioNoMo borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker
    Join Date
    May 2007
    Location
    UK
    Posts
    3,411

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Quote Originally Posted by chopstix View Post
    Sweet!! ANOTHER junky couple spawned from opiophile. <3<3<3
    Sweet - as long as :

    a) I'm tops
    b) My GF can watch

    oh, I practice safe-sex....
    Reply With Quote Reply With Quote
  8. 05-05-2012 05:15 PM #8
    radioactive_man
    radioactive_man is offline
    Never Looked Back radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man has much to be proud of radioactive_man's Avatar
    Join Date
    Mar 2012
    Location
    NW MT
    Posts
    1,050

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Hold on boro, let me get my camera, wife, and the lights.

    Should I keep the wig on?


    Vampires are lucky, they can feed on others. We gotta eat away at ourselves. We gotta eat our legs to get the energy to walk. We gotta come, so we can go. We gotta suck ourselves off. We gotta eat away at ourselves til there's nothing left but appetite. We give, and give and give crazy. Cause a gift that makes sense ain't worth it. Jesus said seventy times seven. No one will ever understand why, why you did it. They'll just forget about you tomorrow, but you gotta do it.

    Bad Lieutenant (1992)
    Reply With Quote Reply With Quote
  9. 05-05-2012 05:26 PM #9
    borohydride
    borohydride is offline
    OpioNoMo borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker borohydride is one bad motherfucker
    Join Date
    May 2007
    Location
    UK
    Posts
    3,411

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Quote Originally Posted by radioactive_man View Post
    Hold on boro, let me get my camera, wife, and the lights.

    Should I keep the wig on?
    You ARE a superhero!!! - I just think of your name & there you are.... yes, the input of you guys is vital. Since I am diabled, Doc. D will have to do 'reverse cowgirl' or, I suppose, 'reverse cowboy' on top of me but it should be good for getting footage.

    I'm no expert on filming this stuff but I believe these is such a thing as a 'pussy light' designed to light the starlets 'area of interest' so I presume an 'arse light' would work on the same general principals...

    Man, this site is just SO supportive. I hardly know Dr. D and yet he implores me to perform anal intercourse with him and being that I am a gentleman, how can I say no?
    Reply With Quote Reply With Quote
  10. 05-09-2012 06:13 AM #10
    doctor diesel
    doctor diesel is offline
    Never Looked Back doctor diesel has disabled reputation doctor diesel's Avatar
    Join Date
    Feb 2005
    Posts
    4,140

    Default Re: Fewest Carbons (lowest MW?) for opioid

    Quote Originally Posted by borohydride View Post
    You ARE a superhero!!! - I just think of your name & there you are.... yes, the input of you guys is vital. Since I am diabled, Doc. D will have to do 'reverse cowgirl' or, I suppose, 'reverse cowboy' on top of me but it should be good for getting footage.

    I'm no expert on filming this stuff but I believe these is such a thing as a 'pussy light' designed to light the starlets 'area of interest' so I presume an 'arse light' would work on the same general principals...

    Man, this site is just SO supportive. I hardly know Dr. D and yet he implores me to perform anal intercourse with him and being that I am a gentleman, how can I say no?
    Well, you can't say no - t'would be improper. And hurtful.
    Yes, I could clip one of those USB keyboard lights to your coccyx so I can see where I'm going.
    And I want some teabagging as foreplay.


    Doc
    TOP JUNK FROM TOP JUNKIES
    PAUPS "A long, narrow foot usually matches a long, narrow face, while stubby toes usually belong to beady eyes"
    DAK "People are worried I'll get so skinny I fall through my asshole and hang myself"
    CHOPS "You gotta be pretty smart to know you're stupid"
    JAMESDIGITS "I've seen horrible people in clinics and had to wait outside due to the stench"
    MAKITA "It wasn't MRSA and it wasn't necrotic fasciitis, it was just some fucked-up shit*"
    *Medical term
    Reply With Quote Reply With Quote
+ Reply to Thread
« Phenylmorphans | the bleeding edge... overdose / death »

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts

Forum Rules