This is a post mainly for the person who maybe is somewhat new to bupe, or recently got themself in a situation where they developed a very decent sized habit and is now going to bupe or thinking about going to bupe.
I am curious how many of you were still in partial-detox after dosing bupe coming from a large heroin habit? I find it strange that it is not talked about more... people with huge habits wonder why they only feel somewhat better when inducing bupe. It seems pretty obvious to me, but bupe is not a simple chemical. For one, you are replacing a full-agonist with a partial-agonist (I know norbupe is a full-agonist), but in that sense you are still going to be in partial detox until your body adjusts. Then there is the ceiling effect. Every doctor I've talked to says that if you have a large habit (1/2g or more of fire shit per day), just take more bupe. This is logical based on what all doctors know about opiate dependency and drugs, etc. However IME, it doesn't work. Me for instance, I hit the ceiling effect really early.
Let's say I've been doing a lot of dope, I could do close to a gram of strong ass dope in a day if I wanted to without breaking much of a sweat. My tolerance is through the roof and I've been using for three months daily. If I stop doing dope, let myself go into withdrawl, and take some buprenorphine, I know I'm only going to feel somewhat better for about 3 days, with each day being better than the last. This makes sense since the worst of a cold-turkey heroin detox is over in 3 days. I also know that taking any more than 6-8mg subL, 4mg Insufflated, or 2mg IV, is not going to do a goddamn thing. By day 4 or 5 on bupe I feel like a human again.
So to anyone who has a tolerance high enough that God is shaking his head at you, remember you are going to need to wait it out for a few days before you start to feel decent again if you are commited to staying off of heroin or other opiate DOC. Bupe is not methadone.
And while it is very difficult on heroin to taper yourself down, the transition is much smoother if you can lower your heroin tolerance before the switch. I remember the first time I went on bupe. I had tapered myself down to like 10mg of morphine IV 2x per day. That was a painless transition. I felt great after my first dose of bupe.
All to say, even better than lowering your tolerance prior to switching, don't let your tolerance get out of control to begin with! I don't understand why I couldn't just use for 3 days and then switch back without much of a hassle, but no I have to use for a month straight and then have to take days off work just to stabilize on bupe. Ridiculous.
Anyway, I'm at day 6 on bupe after being severely strung out since June. I'm feelin' great. I finally put my sobriety above work (unfortunately had to quit my job), and now I'm ready to get back to the things I love in life that are not heroin.
Peace from PDX,