I love potentiating opiates with a *tiny* dose of buprenorphine
So first off, it is known that when it comes to using buprenorphine, the less you use, the better, because the metabolite norbuprenorphine is a full agonist rather than a mixed agonist/antagonist, AND it is stronger. So I usually snort like .2mgs of bupe at a time (I break off a tiny chunk of a 2 mg pill and snort it)
It is also known, that a small dose of buprenorphine, enough to bond to a small percentage of opiate receptors but nowhere near enough to fill them all up, can actually potentiate (cause other opiates to feel stronger at smaller dosages regardless of ROA)
This has recently become my favorite form of potentiation, especially if I snort .2mgs if bupe, then like 8 hours later (once the naloxone has fully worn off and the norbuprenorphine has been created and bonded to my receptors) if I even pop like 5 mgs of oxy and a 350 mg soma I can catch a nice buzz. Nothing special, but with my tolerance its a MIRACLE that 5mgs of oxy and a soma will even do anything other than make my pain level go down a notch or two.
What are your experiences with this? It takes a little bit to get the hang of, but I'm tellin ya, for someone who normally takes well over 100mgs oxy for recreation, (I try to keep my tolerance low and is on fentanyl patches for a daily pain med to get a buzz off 5 mgs of oxy (and a soma), theres gotta be somethin worthwhile goin on. I wish there were more studies about this, and I would really like to come across some.
I wonder if it's possible that wearing one of those buprenorphine patches could help potentiate other opiate pain med regimens by quite alot? The potentiation effects seems to be quite profound, at least for me, and I know some other people who have tried it and been amazed as well. What are your thoughts? Experiences? Trolls? (jk, fuck off lol)