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Thread: whats the best heroin potentiator? both legal and nonlegal?

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    Needle whats the best heroin potentiator? both legal and nonlegal?

    i find benzos and benedryl can help with the nod. but what do a few of u guys and girls like to mix it with? i shoot up my dope. so i guess keep that in mind when u list the best potentiators.... if it matters from any ROA's


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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    cetirizin, grapefruit-juice but mostly 1 beer within 30 seconds, half a 40ml bottle wodka gorbatschow immediately after and then the h. when the alc and the "dope" come together it gives a nice nod.

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Since I've been in bartending school, I've developed the habit of making a few Greyhounds (vodka + gfj) and using the first one to wash down a few mgs of Xanax or Vistaril, whichever I happen to have at the moment.

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    yeah, cause mixing benzo and alcohol with opiates is just so good for you...


    real good cocktail to kill yourself, genius....

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    lol you know how dumb you sound? OF COURSE no one on here ever does any remotely dangerous

    Quote Originally Posted by 604 View Post
    yeah, cause mixing benzo and alcohol with opiates is just so good for you...


    real good cocktail to kill yourself, genius....


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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    methamp
    not quite poptentiator but it's a hell of anexperience

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by SHELLEY View Post
    methamp
    not quite poptentiator but it's a hell of anexperience


    lol. you are officalll strung the fuck out. Talkin bout meth completely off topic.

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Actually, this was the only sensible response to this thread. Not to mention that this whole thread is a complete waste of server space since this has been covered somewhere along the line of 58,326,521 times in various forms.

    And, Havok, while I do agree that we are not a low risk crowd (I am about to engage in a combo I would never recommend to anyone due to its' danger- beer is the final ingrediant and I am cracking one open now), but this really is the kind of thread that some 16y/o dipshit with more drugs than sense will see and then give their parents the gift of finding little Billy all blue, cold, and stiff.

    So maybe the one person who is saying the one thing worth saying in this thread doesn't sound that dumb.

    Potentiators are a joke. There are certainly combos that are nice (like what shelley is saying), but the whole idea od "potentiators" relegates itself to peeps trying to make their norcos last longer with some GFJ.

    Now there are certain substances that will inhibit bodily enzymes that help metabolize certain drugs, thereby making the drug last longer... So that is a valid form of potentiation. But the whole benadryl-helps-the-nod thing... Well, whatever floats your boat. I don't know that adding the drowsiness side effect of benedryl to a dope high is anything but a dope high coupled with a desire to sleep. Again, if you like that- well, right on. Whatever you like aint for me to say. So don't take this statement like I am baggin on you for that.

    But anyone with a dope habit who tries this kind of shit for long enough is gonna regret it at some point. I know this from both observation and experience.

    But seriously, OP, there is SO much stuff on this. Also, you can insert any strong opiate into the search to substitute for heroin for the purpose of the search.The only "real" potentiation that you can get out of morhine, heroin, et al is an extension of duration and an increase in pain control if you subscribe to the medical definition of potentiator. But you better understand the relationship between various liver enzymes and first pass metabolism, as well as the mechanism of action of various neurotransmitters.

    Otherwise you will end up throwing a bunch of silly stuff down the hatch and getting a bunch of psychsomatic, placebo effect.

    OP, not baggin on ya bro, but seriously... There is SO much stuff on this.

    Just be careful man.


    Quote Originally Posted by havok View Post
    lol you know how dumb you sound? OF COURSE no one on here ever does any remotely dangerous

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by mainline View Post
    I use Cyclzine religiously.
    Cyclizine was removed from OTC sales in the UK because of people mixing it with opioids in their shots. There have been a few examples of pharmacists being struck off for selling the pills to addicts. The most euphoric opiate rush of all (I do not say this lightly) is from the drug Diconal (also known as Weconal) which contains 10mg dipipanone + 30mg cyclizine. In the UK there are only 3 drugs that a doctor requires a home-office licence to prescribe - Heroin (diamorphine), Cocaine & Diconal. They used to contain a very dangerous filler in the pills, but this was changed some years ago...

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by borohydride View Post
    Cyclizine was removed from OTC sales in the UK because of people mixing it with opioids in their shots. There have been a few examples of pharmacists being struck off for selling the pills to addicts. The most euphoric opiate rush of all (I do not say this lightly) is from the drug Diconal (also known as Weconal) which contains 10mg dipipanone + 30mg cyclizine. In the UK there are only 3 drugs that a doctor requires a home-office licence to prescribe - Heroin (diamorphine), Cocaine & Diconal. They used to contain a very dangerous filler in the pills, but this was changed some years ago...

    yeah, So I've read. In the states, Cyclizine is an OTC drug sold as Bonine for kids/Marezine (and respective generics). Regular "Bonine" is Meclazine, Which I've never really tried.
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by mainline View Post

    I use Cyclzine religiously.
    how much is this stuff OTC i know nothing about it other than its an antihistamine and i like benadryl sometimes for potentiating and sleep.
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    More heroin..
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by ryan5892 View Post
    how much is this stuff OTC i know nothing about it other than its an antihistamine and i like benadryl sometimes for potentiating and sleep.

    its quite different than benadryl. Its expensive, kinda. Bonine for kids comes in 8 packs of chewable 25mg tabs for around 4$ @ mom n pops. Marzine comes in packs of 12 and it around $12 for small 50mg tablets.
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    Quote Originally Posted by chopstix View Post
    More heroin..
    Lol, beat me to it, that's the only thing that's worked for me and it always worked pretty damn well.

    Quote Originally Posted by mainline View Post
    its quite different than benadryl. Its expensive, kinda. Bonine for kids comes in 8 packs of chewable 25mg tabs for around 4$ @ mom n pops. Marzine comes in packs of 12 and it around $12 for small 50mg tablets.
    I've been liking the pod/trammie combo recently, I might throw some of that in the mix and see what happens.

    edit-sorry for the 2 posts mods, I should have read the whole thread before replying and don't know how to combine them now.
    Last edited by flowergirl; 05-07-2011 at 12:14 PM.

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Turkey baster---> jugular

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by mainline View Post
    yeah, So I've read. In the states, Cyclizine is an OTC drug sold as Bonine for kids/Marezine (and respective generics). Regular "Bonine" is Meclazine, Which I've never really tried.
    Yes I still have yet to find "cyclizine." I have searched many pharmacies and even asked pharmacists, which I was wary of because its abuse potential and banning in the UK. But the pharmacist (lead) had never heard of cyclizine.

    only thing I've found is bonine and that is meclazine, which is similar, but i wasnt about to drop 6 bucks on it.

    marezine is marketed as a motion sickness pill, idk why i cant find it. what am i doing wrong!
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Hydroxyzine. I know it's script only but in my circle at least people have it or can find it easily and don't realize it's helping potential. Check the medicine chest, or some one else's if possible.

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    A simple antihistamine called "Promethazine" is pretty good. It's OTC. (In AU anyways)

    Just taking some of them on their own knocks you on your ass, great for sleep and fully increases a nod and euphoria. You only need the recommended dose too.

    http://en.wikipedia.org/wiki/Promethazine

    Oh, I see its RX in the US.
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    a little pharmaceutical cocaine in the spoon is nice
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by Duckfeet View Post
    a little pharmaceutical cocaine in the spoon is nice
    hells yep -much prefer to spike it though- best combo ever love the synergy-the head trains without the panic-if everything felt like that ..........ahhhhh

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    diphenhydramine.
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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by ryan5892 View Post
    Yes I still have yet to find "cyclizine." I have searched many pharmacies and even asked pharmacists, which I was wary of because its abuse potential and banning in the UK. But the pharmacist (lead) had never heard of cyclizine.

    only thing I've found is bonine and that is meclazine, which is similar, but i wasnt about to drop 6 bucks on it.

    marezine is marketed as a motion sickness pill, idk why i cant find it. what am i doing wrong!
    Order it on Amazon. That's where I got mine. Search Marezine, or cyclizine and WHAM!!!! your good to go.
    I think its like 9-10 bucks tho

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Immodium / Loperamide; is an opioid which doesn't cross the 'blood brain barrier' and is in fact constantly pushed away from it; furthermore it is a class of opioid with affinity nearly of Fentanyl (very potent), which therefore occupies the peripheral non-central-nervous opioid receptors tightly so that true centrally active opioids may occupy more receptors in the brain. I have heard colloquially that this greatly potentiates full agonists which readily penetrate the BBB; and that unwanted side effects like constipation are not as much increased as might be assumed when co-administered. (too bad drugs like methylnaltrexone; antagonists which don't cross the BBB, aren't available to diminish constipation, but apparently this really isn't a problem with loperamide as a potentiator so I've heard: have yet to try it myself)

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    Default Re: whats the best heroin potentiator? both legal and nonlegal?

    Quote Originally Posted by Nagelfar View Post
    Immodium / Loperamide; is an opioid which doesn't cross the 'blood brain barrier' and is in fact constantly pushed away from it; furthermore it is a class of opioid with affinity nearly of Fentanyl (very potent), which therefore occupies the peripheral non-central-nervous opioid receptors tightly so that true centrally active opioids may occupy more receptors in the brain. I have heard colloquially that this greatly potentiates full agonists which readily penetrate the BBB; and that unwanted side effects like constipation are not as much increased as might be assumed when co-administered. (too bad drugs like methylnaltrexone; antagonists which don't cross the BBB, aren't available to diminish constipation, but apparently this really isn't a problem with loperamide as a potentiator so I've heard: have yet to try it myself)
    it doesnt really work that way...

    #1 lope DOES cross the bbb in small amounts and since you saiid (and i agree) its affinity is that of fent. its binds to your CNS receptors... i have taken lope to get well, then a few hours later did A LOT of OC and felt nothing more than the lope

    #2 even if only ur gut receptors are filled, doesnt mean the drug will go to the brain, it wll still circulate everywhere and be metabolized the same

    in theory it sounds like it would increase plasma levels of the drug but im 98% sure it doesnt work that way.. I know from experience it doesnt actually. I thought the same thing though

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