DLPA is an essential amino acid that allows your body to produce more endorphins naturally, also slowing the breakdown of endorphins. It takes about 1.5 - 2 weeks for the dlpa to take full effect, but when it does it can be a successful anti-depressant, pain reliever, and opioid potentiator; increasing the potency, duration, and analgesia of opioids. I myself use DLPA, it has worked wonders for depression too, when I was dependent on Oxycodone, I started using DLPA myself because I had heard such great reviews of it. Normally 80mg of oxycodone would help take the pain away, relax me, you know, normal opioid effects. I never would have believed an amino acid could do this, by 2 weeks, 80mg Oxycodone had me floored (which never happened) the analgesia from it was doubled, if not tripled when using DLPA with this. Duration was doubled, if only I could have found out about DLPA when I first started. DLPA is no joke, this amino acid will double, if not triple the effects of _________ opioid. It is more noticeable with short acting opioids, but it works for long acting too. It allows your body to release more endorphins when you use opioids, hence stronger effects. I highly suggest this to ANYBODY who is looking for a natural way to potentiate their opioids, or as an antidepressant, or an analgesic by itself. You will be very, very surprised by this drug, I know I and everybody else I have recommended it to were overly happy with the results. It will cut your tolerance to opioids by 1/3, if not 1/2. I have never felt any effect from 20mg Oxycodone, but with dlpa it provided strong analgesia. Take a look into it!