Plugging Oxy?




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    Default Plugging Oxy?

    I have a few questions about plugging oxycontin.I used the search bar for several of these questions and didint find anything relevant.

    1.What is the BA of plugging,is it higher then oral?
    2.Is the duration longer then oral or shorter,is longer then snorting it.im not a fan of snorting pill i would rather pop them.
    3.Would the dose be less then oral?
    4.Can i break down a diphenhydramine pill and put it with the broken down oxy and plug both of those at the same time or should i just pop it the benadryl or what not?
    5.would a 1 ml dropper work fine i have used it in the past to plug an oxy
    6.should i take a shat if i can before i plug or does it not have any effect

    I have plugged in the past with i think 60 mg of roxi and it was good..i was thinking about the most random stuff like halfway asleep waiting like 10 min so none dosent comeback out laying halfway over my bed..i was thinking about like bananas and random stuff like that it was great.I didint no all the stats like what i asked in the question though and didnt really no all the benifits.








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    Default Re: Plugging Oxy?

    Quote Originally Posted by KoDeInaaaae View Post
    I have a few questions about plugging oxycontin.I used the search bar for several of these questions and didint find anything relevant.

    1.What is the BA of plugging,is it higher then oral?
    2.Is the duration longer then oral or shorter,is longer then snorting it.im not a fan of snorting pill i would rather pop them.
    3.Would the dose be less then oral?
    4.Can i break down a diphenhydramine pill and put it with the broken down oxy and plug both of those at the same time or should i just pop it the benadryl or what not?
    5.would a 1 ml dropper work fine i have used it in the past to plug an oxy
    6.should i take a shat if i can before i plug or does it not have any effect

    I have plugged in the past with i think 60 mg of roxi and it was good..i was thinking about the most random stuff like halfway asleep waiting like 10 min so none dosent comeback out laying halfway over my bed..i was thinking about like bananas and random stuff like that it was great.I didint no all the stats like what i asked in the question though and didnt really no all the benifits.
    Oxy has high oral bio so there isn't much point into plugging. I can only give you anecdotal information about rectal bio, but it seems quite high, greater than 90% I would guess. Unfortunately if you're backed up some of your dose can get absorbed by feces, so it's hard to know exactly how strong it will be when plugged.

    About the diphenhydramine--I imagine you can plug it but first a word of warning. Some drugs burn like HELL when plugged and will give you instant painful diarrhea. I know this from experience, as one time I plugged some phenergin along with some oxy, and man did it fucking hurt, for HOURS. So if I were you I wouldn't risk it. What's the point of plugging an antihistamine anyway? To increase the bio? Again, what's the point? It's cheap. Just swallow them.

    A 1 ml dropper may be enough, but it could require multiple fillings. I usually use a 5 cc oral syringe with 2 - 3 fillings depending on how much powder I'm dissolving.

    Take a shit first if you can, it will help with the bio.

    I don't think the duration is much different than any other method of taking oxy, assuming you've crushed them up to break the extended release of course. It might wear off faster than oral because it seems to hit quite a bit faster, but the duration from onset should be the same.

    I think plugging oxy is a little stronger than taking it orally, but not much. May not even notice it. You do get more of a rush though, but nothing compared to IV.

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    Default Re: Plugging Oxy?

    I always imagine my opie highs as a graph between time and plasma levels. The shorter it is from left to right, the less time it lasts. The highest point it reaches is the "peak", the highest part. If the peak is at the very beginning you will have a rush.

    This being said, plugging is almost exactly like eating except the duration is shorter and the peak is higher. You use a smaller amount of oxy when doing this, get a shorter experience, but it can still be relatively intense. The anus is rly a wonder, aint it??

    1 - varies but slightly lower than oral
    2 - answered above, shorter
    3 - answered above, smaller doses will reach similar plasma levels
    4 - Yes. I think I tried it once but don't remember what happened, but I know i've read of people doing this so it should be fine. Worse possible thing that could happen would be it doesn't add anything, but it def can't hurt unless you use too much. I wouldn't go over 50 mg till I was comfortable because it isn't made for being plugged
    5 - 1 ml dropper will be fine for up to about 75 mg of oc. You could do more, especially with hotter water, but you start to reach the saturation point of the water. If your putting in difed too you should do 2 runs, or get a new oral from the pharm.
    6 - Water will absorb into your dookie if there is dookie there. Also, I hate taking a dookie coated syringe out of my bottom. Poop before, always, if you can.
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    Default Re: Plugging Oxy?

    http://forum.opiophile.org/showthread.php?t=7252

    The Oxycodone released from OxyContin Tablets is pH independent. Oxycodone is well absorbed from OxyContin Tablets with an oral bioavailability of 60% to 87%. The relative oral bioavailability of Oxycodone in immediate-release oral dosage forms is 100%.
    Data from a study involving 21 normal volunteers show that OxyContin Tablets administered per rectum resulted in an AUC 39% greater and a Cmax 9% higher than tablets administered by mouth. Therefore, there is an increased risk of adverse events with rectal administration.
    Straight from the tablet insert


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    Default Re: Plugging Oxy?

    That's oxyCONTIN rectally. I doubt he's using oxycontin suppositories and not crushed up liquid solutions or roxicodone.

    The oxycodone rectal BA is 10.77%-17.37% lower than oral

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    Default Re: Plugging Oxy?

    Quote Originally Posted by antifox View Post
    That's oxyCONTIN rectally. I doubt he's using oxycontin suppositories and not crushed up liquid solutions or roxicodone.

    The oxycodone rectal BA is 10.77%-17.37% lower than oral
    Source on this figure? I've always seen rectal admin BA of oxycodone to be very close to that of oral, always over about 70 percent and as high as 85 or 90. This of course varies from person to person and situation to situation depending on things such as the exact procedure (pill in pooper, or solution squirted) or weather or not you have "other things" in your chute... but overall when done proporly plugging is very efficient.

    As I am aware, plugging is SLIGHTLY less efficient than oral dosing, but because of the shorter onset and shorter overall duration, the peak ends up being higher.
    Nothing I post on this website is true, everything posted was fabricated while under the influence of illicit drugs.

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    Re: Plugging Oxy?

    UTMFSE. (I'm not trying to be mean or anything.It will take some time going through the threads, but you'll find answers to your questions and more)
    Last edited by Ickyuck; 09-07-2009 at 08:01 AM.

    "People Wouldn't Shoot Up If It Didn't Feel Good "

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    Default Re: Plugging Oxy?

    Quote Originally Posted by Thai_Stick View Post
    Source on this figure? I've always seen rectal admin BA of oxycodone to be very close to that of oral, always over about 70 percent and as high as 85 or 90. This of course varies from person to person and situation to situation depending on things such as the exact procedure (pill in pooper, or solution squirted) or weather or not you have "other things" in your chute... but overall when done proporly plugging is very efficient.

    As I am aware, plugging is SLIGHTLY less efficient than oral dosing, but because of the shorter onset and shorter overall duration, the peak ends up being higher.

    I have a textedit file over BA's that i've looked up one weekend when I had surgery. I have that figure there, so I got it from a journal, so I am sure it's legit.

    Oral dosing at 85% means that rectal would be around 70%-75%. that IS slightly less.

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    Default Re: Plugging Oxy?

    I see no one has answered the most pressing question contained in your post.

    YES, YOU SHOULD SHIT. If you don't do that, your feces will be nodding and you won't.

    That is all.

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    Default Re: Plugging Oxy?

    OHHHHH... I am so sorry I read it wrong. I thought it just said 10-17% BA, not 10-17% lower BA. Completely my fault!

    Good luck, butt pirate!
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    Default Re: Plugging Oxy?

    Oxy has 90% BA PO, so there's no point in plugging, or shooting it IMO, for that matter. I always preferred eating oxy even when I was on the needle. It came and went too quickly - I don't like the rush, I like the nod. The best action you're going to get is from swallowing your OC, crushed, IMO, unless you're looking for a rush. The thing you described liking so much was the wonderful nod. It will work just as well on just as low of a dose eating it as well as plugging it, without the hassle of putting shit up your ass. I tried plugging OC once. IMO it does come on a bit quicker, but that's it. Nothing worth the hassle of shooting something in my rectum.

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    Default Re: Plugging Oxy?

    Quote Originally Posted by Maintenance Man View Post
    Nothing worth the hassle of shooting something in my rectum.
    Especially when you are already full of shit eh?
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    Default Re: Plugging Oxy?

    Quote Originally Posted by antifox View Post
    That's oxyCONTIN rectally. I doubt he's using oxycontin suppositories and not crushed up liquid solutions or roxicodone.
    The oxycodone rectal BA is 10.77%-17.37% lower than oral
    First off, there is no such thing as OxyContin suppositories. If you bothered to read the quote that I posted you would have seen that it said OxyContin TABLETS.

    Again:

    Data from a study involving 21 normal volunteers show that OxyContin Tablets administered per rectum resulted in an AUC 39% greater and a Cmax 9% higher than tablets administered by mouth. Therefore, there is an increased risk of adverse events with rectal administration.
    The other quote, also straight from Purdue's package insert, shows the oral BA of OxyContin tablets and compares that to the IR form.

    The only difference between Oxycontin tablets and Oxycodone IR is the time release matrix. So I would be willing to bet that Oxycodone IR administered via the rectum also results in increased absorption.


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    Default Re: Plugging Oxy?

    Quote Originally Posted by Maintenance Man View Post
    Oxy has 90% BA PO, so there's no point in plugging, or shooting it IMO, for that matter. I always preferred eating oxy even when I was on the needle. It came and went too quickly - I don't like the rush, I like the nod. The best action you're going to get is from swallowing your OC, crushed, IMO, unless you're looking for a rush. The thing you described liking so much was the wonderful nod. It will work just as well on just as low of a dose eating it as well as plugging it, without the hassle of putting shit up your ass. I tried plugging OC once. IMO it does come on a bit quicker, but that's it. Nothing worth the hassle of shooting something in my rectum.

    You're right in does have an excellent oral BA. But if you read my post above, which quotes excerpts from Purdue's PI for OxyContin,
    Data from a study involving 21 normal volunteers show that OxyContin Tablets administered per rectum resulted in an AUC 39% greater and a Cmax 9% higher than tablets administered by mouth. Therefore, there is an increased risk of adverse events with rectal administration.
    For the record:
    AUC = area under the curve
    Cmax = maximum concentration

    In bioequivalence studies, the maximum concentration (Cmax) is shown to reflect not only the rate but also the extent of absorption. Cmax is highly correlated with the area under the curve (AUC) contrasting blood concentration with time. Therefore, use of the Cmax/AUC ratio is recommended for assessing the equivalence of absorption rates. The ratio is independent of both intrasubject variations and possible differences in the extent of absorption and reflects only the contrast between the absorption and disposition rate constants (ka/k).


    ..... found that when it got *really* bad, I'd cop, and fuck all that detoxing, whether I'm eating carrots and brown rice, or vodka and cough drops, I've learned only one sure thing about detoxing:
    There Ain't No Free Lunch!.......Originally posted by Duckfeet

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    Default Re: Plugging Oxy?

    I was wondering something about plugging OC and plugging in general. Obviously somebody who uses opiates regularly tends to be backed up quite a bit and probably doesnt shit too often. I know that when plugging its recommended to have a BM before you plug, but if you've got a habit and don't take shits very often would plugging not even be worth it? If you only shit like twice a week would the solution just be absorbed into your doo doo?

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    Default Re: Plugging Oxy?

    Preemptive enema!


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    Default Re: Plugging Oxy?

    Ive got I.B.S so im backed up 24/7 and ive plugged about 5 times each time i didn't really take a shit before hand and it was never a problem. I would just say don't do it if you have to take a shit which is pretty obvious. I was taking 200mg of morphine at the time orally. When i did it i plugged 60mg and definitely felt it, but i preferred taking my oral dose.

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