VERY interesting chemical

[TappyTibbons]

A private vendor that I use has just added this chemical to it's list, and I found it really really interesting. I've never heard of something like this

CP 55,940, is a cannabinoid (http://en.wikipedia.org/wiki/Cannabinoid) which mimics the effects of naturally occurring THC (http://en.wikipedia.org/wiki/Tetrahydrocannabinol) (the psychoactive compound found in marijuana (http://en.wikipedia.org/wiki/Marijuana)). CP 55,940 was created by Pfizer (http://en.wikipedia.org/wiki/Pfizer) in 1974 (http://en.wikipedia.org/wiki/1974) and was never marketed because of its highly psychoactive nature. It is currently used by scientists to study cannabinoid effects in biology. Some effects that have been noted are a greatly decreased rates of lever pressing in exposed mice, and a greater reaction to opiates in exposed mice. CP-55940 is 40 times more potent than Δ9-THC, and fully antagonized by rimonabant (http://en.wikipedia.org/wiki/Rimonabant) (SR141716A) (Life Sci 1996;58:1239-47; last update 010106). CP 55940 produces cannabis-like effects in humans at a dose of 0.25 - 1 milligram and could potentially be used as a legal alternative to medicinal marijuana (http://en.wikipedia.org/wiki/Medicinal_marijuana) but is unlikely to be marketed for this purpose due to its abuse potential.

http://en.wikipedia.org/wiki/CP_55,940

Especially interested in it's extremely low dose and its value as far as potentiation goes!

[DarthPerineum]

Whoa, thats sounds like it be a good time. Ill have to swing by and check some out sometime. Have you picked any up for yourself, if so have you tried it solo or mixing it with other stuff? how does it affet them?

[jacky]

hmmm.

interesting.

I find one company selling this stuff for 70$ for 5 milligrams.

with a dosage range given 1/4 milligram to one milligram.

40x more potent than thc doesnt mean that it is going to FEEL 40x more potent.

when the worlds best cannabanoids are easily available all over the world, I think my investigative urge is not enough to venture into this particular type of research chem

dysphoria/dissasociation is probably a possibility with the bioassay of this material.

I have had some EXTREMELY uncomfortably symptoms from consuming too much THC/CBN.....I was nearly unable to take care of myself for 5 hours. wracked in SEVERE pain, my heartrate was at 90-120 beats per minute for HOURS. hallucinating similiar to a dxm overdose.
I couldnt straighten out and lay comfortable, my stomach muscles were cramping me, and I was bent over at nearly a 90 degree angle for hours as I simply could not stand up straight.
this thc/cbn overdose was not intentional...some niave hippy girl simmered stems/shake for hours in milk, and didnt realize that she had given me the equivalent to a few ounces of high quality weed extracted in milk. (she is a dealer/lots of leftovers)
the pain of this experience left me after about 9 hours of not sleeping all night. at 8am I was finally able to fall asleep, exhuasted.

that experience leads me to believe that cannabis is not quite as safe as people want to believe.

another thing to be careful with this compound might be the info that smoking cannabis can up your chance of heartattack 400 percent within the first hour of smoking.
see, cannabis consumption in the beginning releases dopamine, that is part of THC's complex effects, and some hypothesize that dopamine release can put a strain on SOME peoples hearts.

so with a cannabis alternative assayed at some 40x the potency of THC, I would be VERY careful.

[Sitar]

I can attest to the extreme unpleasant effects that overdosing on oral THC can be.

I had what could only be described as an incredibly bad trip that lasted at least 11 hours and included visual and auditory hallucinations. Really nightmarish experience. And this was from only consuming a couple grams.

I was spared any physical pain in this experience, but psychologically it was pretty damn rough.

[MrCream]

well I dunno bout you guys but pot just gets me high and feeling good so bring it on :P, although I do prefer to smoke pot for the taste and enjoyment of the situation, I think I could handle it :P <3

[OxyContinuously]

well I dunno bout you guys but pot just gets me high and feeling good so bring it on :P, although I do prefer to smoke pot for the taste and enjoyment of the situation, I think I could handle it :P <3


sup Mr.C

yeah this topic came up a couple mos. ago...one very, very important thing to realize about this chem, is that it was made in a lab (by a chemist like me--not "me" specificelly, I didnt make it, but S/O like me) and I guess the point is that sometimes "chemicals based on nature' as i like to dub them can be startling in their intensity and effects....remember that when u smoke weed, even the best weed u can think of, or get, your not only getting Delta 9 thc, but a myriad of other inert, maybe partially active chems that ALL TOGETHER give you the weed experience...

Quick example: Recently my dude got his grubby little mitts on something called "Marinol" (I don't know if you've heard of that but it is a synthetic THC, basically) So these Marinols come in 2.5, 5, and 10 mg formulations. Like you, I like smoking chronic, you know? So I took a couple of the tens (which look lile little balls filled with some shit, kinda like an advil liquigel, or something, but they're round, real small like a little smaller than a green pea, and they're orange.

So me, thinking I know all about weed, cause i smoke it all the time took two ten mg pills and smoked a blunt...bottom line, foolish move on my part...I got the most intense weed experience of my life that night! I mean paranoia, body tingles, weird weird thoughts, bro, time dilation and general disorientation...all this lasted a solid four or five hours, of course at the time it seemed like a century, LOL...

Anyway, this new chem referred to in the thread is even more POTENT than the Marinols...so just be careful and start small....real small....work up....listen a weed "overdose" if u can ever even really call it that, is *quite* unpleasant. hope that helped a bit, an oh if you do ever try it, please just try it by itself at first, like dont have a blunt also, u know? see how u react to it, and work from there ;-)

good luck
later
peace out

Oxy

[CSiiSEQ]

This has been around for a long time and used to study canabinoid receptors. I can't tell you much about the human response to it, never tried it personally and don't even like d-9 to start with so my opinion wouldn't be helpful. I can tell you that canines prefer CP to straight d-9 if given the choice.

[Hammilton]

a d-9-THC OD can be absolutely horrendous, I have to agree with Jacky on that count. For those who've only smoked it, taking it orally will be a hugely different experience. Smoked, you can only get so high, but if you eat it, it seems the skies the limit.

The nature of the experience changes drastically. It's truly a psychedelic at medium-to-high oral doses. But it's a psychedelic greatly different from the tryptamines and phenethylamines. I'd actually say it's more similar to the dissociatives, but a very mild dissociative, I suppose.

If I could get my hands on an unscheduled THC-analogue, I'd love to give it a try. Hell, if it was good enough, I'd purchase enough for decades.

[soulninja]

sup Mr.C

yeah this topic came up a couple mos. ago...one very, very important thing to realize about this chem, is that it was made in a lab (by a chemist like me--not "me" specificelly, I didnt make it, but S/O like me) and I guess the point is that sometimes "chemicals based on nature' as i like to dub them can be startling in their intensity and effects....remember that when u smoke weed, even the best weed u can think of, or get, your not only getting Delta 9 thc, but a myriad of other inert, maybe partially active chems that ALL TOGETHER give you the weed experience...

Quick example: Recently my dude got his grubby little mitts on something called "Marinol" (I don't know if you've heard of that but it is a synthetic THC, basically) So these Marinols come in 2.5, 5, and 10 mg formulations. Like you, I like smoking chronic, you know? So I took a couple of the tens (which look lile little balls filled with some shit, kinda like an advil liquigel, or something, but they're round, real small like a little smaller than a green pea, and they're orange.

So me, thinking I know all about weed, cause i smoke it all the time took two ten mg pills and smoked a blunt...bottom line, foolish move on my part...I got the most intense weed experience of my life that night! I mean paranoia, body tingles, weird weird thoughts, bro, time dilation and general disorientation...all this lasted a solid four or five hours, of course at the time it seemed like a century, LOL...

Anyway, this new chem referred to in the thread is even more POTENT than the Marinols...so just be careful and start small....real small....work up....listen a weed "overdose" if u can ever even really call it that, is *quite* unpleasant. hope that helped a bit, an oh if you do ever try it, please just try it by itself at first, like dont have a blunt also, u know? see how u react to it, and work from there ;-)

good luck
later
peace out

Oxy



I once got ahold of some marinol and had a blast on it.I only took one 10mg(little orange ball) at a show andhad a great time.Was more of a body effect than smoking bud.I can see how taking too much could be a bad thing though.

[AZJunkie]

How readily available are these Marinols?

You've piqued my curiosity......

[soulninja]

How readily available are these Marinols?

You've piqued my curiosity......


I dont know how readily available they are.But i got a few at a Legalization rally at a college in Pa.Some guy was just blatantly handing them out.So of course i had to try it.Havnt seen any since though.Sorry not alot of help.

[halfalien_s4]

marinol is definatly a drug i would like to do. one of my ex bfs used to have leukemia and had some marinol. he said he got really high off of it. ingestion is the only way u can od on marijana/THC. fortuantly ive neve expirienced it. from what i understand, u have major tachacardia, profuse sweating, hallucinations, nausea, headache, vertigo, ect. i know theres other effects too. but those r the major ones. definatly doesnt sound comfortable to me tho. pot brownies or any other for of cannabis - containing food is something that i havent had the honor to try yet. from what i understand the high from ingestion is different from smoking. on another board in another group im in we started a topic on marijana tictures. if i remember correctly, u take a bud and cook it a certain way (dont remember exacly) and after it set for a certain ammount of time there would be crystals formed on it. u would then scrape off the crystals into a bag. Then whenever u wanted too, take out a minutely small bit of crystal and stir it up in a little bit of water, tea, or whatever. not much was needed to dilute it in tho, i may however maybe telling some of this wrong. i guess i could go back and re-read that post and then post a thread with th erecipe. ill let everyone know...

[jonny-5]

ingestion is the only way u can od on marijana/THC.



accidental OD from marijuana is IMPOSSIBLE. you would have to ingest 5 lbs of weed to overdose. nobody does that on accident, and im sure the amount of THC in marinol caplets is no where near the amount it would take to OD, even if you took a whole bottle of em.

[Hammilton]

accidental OD from marijuana is IMPOSSIBLE. you would have to ingest 5 lbs of weed to overdose. nobody does that on accident, and im sure the amount of THC in marinol caplets is no where near the amount it would take to OD, even if you took a whole bottle of em.

you're a good long-time member here, but that is absolutely not true. Not even remotely. Even an ounce of good weed, properly prepared and taken orally will produce absolutely hellish results.

I can't even imagine how horrid 5 pounds would be.

If you're taking the term overdose to include only deaths, then you're probably right. I doubt anyone could eat enough to cause death, but there are things worse than death, for certain.

[TappyTibbons]

I have had some pretty bad times eating edibles. I used to work @ a medical dispensary in san francisco and we sold lots and lots of differn't strength's of edibles. Some were only meant to be eaten in peices. like 1/8th of a snickers bar type thing... but being stupid I had times where i was hungary and ate a whole one thinking ti was just weed......... The shit always creeps up on you, it wasn't until I was done with my shift and sitting on the bart train going home, that I started feeling the effects. It was awful..... trying to keep composure it public. For me it all depends on where I am at. It all depends on what you mean by the term overdose. If you mean the point where you begin to feel adverse side effects... or even adverse side effects that overpower the good side effects, then yeah, overdosing on weed happens very often. In terms of physical side effects.. health related... maybe not.

[Boudica]

I have had some pretty bad times eating edibles. I used to work @ a medical dispensary in san francisco and we sold lots and lots of differn't strength's of edibles. Some were only meant to be eaten in peices. like 1/8th of a snickers bar type thing... but being stupid I had times where i was hungary and ate a whole one thinking ti was just weed......... The shit always creeps up on you, it wasn't until I was done with my shift and sitting on the bart train going home, that I started feeling the effects. It was awful..... trying to keep composure it public. For me it all depends on where I am at. It all depends on what you mean by the term overdose. If you mean the point where you begin to feel adverse side effects... or even adverse side effects that overpower the good side effects, then yeah, overdosing on weed happens very often. In terms of physical side effects.. health related... maybe not.


I could not agree with you more, TT. Also, I think that the effects of pot can vary widely from person to person. I, for one, cannot use pot, smoked, at even the smallest amount. One hit of today's powerful hybrids and it causes psychotic effects that have taken days sometimes to wear off, and allow me to feel "normal" again. It magnifies every negative feeling I have about a thousand times, brings to mind every negative, horrific experience I've ever had, and I can't "make them go away" no matter what. It takes over my whole thought process, my whole being. Paranoia, fear, sadness, emotional pain in the biggest way imaginable. If that ain't a "bad trip" I don't know what is. I've had so many people ask me, because of my illness, "oh have you tried medical marijuana?". Oh yeah. And the last time was my LAST time!!! I live in a county where med mj is legal, I can get the little card and go to the cannibus clubs, and all that stuff. A godsend for pot lovers, a hell for me. I find that I can eat it, tho, in very minute amounts, which I either encapsulate or bake into cookies, and it helps with nausea and insomnia, brought on by the chemo drugs I sometimes have to take.

But other than that, I would consider every "THC experience" I've ever had, an "overdose".

[oxydose]

OxyCon

From what a good friend told me the way to go with those Marinol pills is too prick a hole in the thing, and lace up a joint with the juice, then let it dry.

never had them myself but the friend who told me is a very good one, he wouldnt BS me about them. give it a try

[mrnatural]

OxyCon

From what a good friend told me the way to go with those Marinol pills is too prick a hole in the thing, and lace up a joint with the juice, then let it dry.

never had them myself but the friend who told me is a very good one, he wouldnt BS me about them. give it a try


That's the way I did it, and it was intense. We dribbled on some rolling papers and let it dry, then rolled. Used to do the same thing with this stuff called hash oil in the early-mid seventies. Had a good friend whose neurologist prescribed it for him for his ALS. Thought it was just for cancer patients, but he got a shitload of marinol for a neural illness (terminal). Lot of other good stuff too that they gave him out of sympathy, maybe. cause we would make up symptoms that he really didn't have. It wasn't as cold blooded as that might sound.

Ingestion of cannabis is really different from smoking it. I'd tell people that it took a while to get off, but you stayed off until you finally slept. GF and I cooked a quarter ounce of green Morrocan hash in some brownies and drove from Shenandoah Park in Va to Denver over Labor Day in 1972, with a brief stop at Antioch College in Ohio, in about 45 hours and hardly felt any fatigue, we were so wired. When we crashed though, we slept for 24 hours. I don't know if my body is up to doing things like that anymore, but I'd like to try this chemical in moderation. Moderation, hell. I'm an addict.

[Paregoric Kid]

I would like to try nabilone I hear it is "better" than marinol (dronabinol) and I think it's structure is closer to actual THC. it's also still schedule II instead of dronabinol which got moved down to schedule III. there are a lot of cool synthetic cannabinoids, I remember reading an old book that talked about parahexyl and synhexyl which were potent. and then there is THC-V and THC-VI which are extremely potent. a friend of mine who was taking chemistry in college wanted to try and extract anandamide from chocolate, sounds fun, I mean even if it didn't get us high who else can say they've tried that lol.
speaking of stems and stuff in milk one time a friend of mine gave me a plant he picked or maybe it was a male plant, at any rate, I chopped it up really good and soaked the whole thing in milk with a little bit of alcohol, it definitely got me stoned.
I still think cannabis is extremely safe, especially when you compare it to other drugs. there is no recorded case in human history of a fatal cannabis overdose. it just doesn't act on the right parts of the brain to be deadly to us. not to say you can't have an unpleasant experience.
hey jacky any info on plants with "good" cannabinoids in them?
I wonder if you could cross hops and cannabis since they are in the same family.

[Paregoric Kid]

question, would a chemical like nabitan (Benzopyranoperidine) be "legal" since it is an analogue of dronabinol which is CIII and the analogue act only covers analogues of CI and II drugs

[mrklean]

I'm pretty sure that I have read an article on crossing hops and cannabis and there is some good reason to do it too I just don't remember the details. I bet the ol OG forums have plenty on that subject.
I dont really see a marinol analogue (does that rhyme?) being too much fun. Although, if someone makes it cheap enough and it isn't covered by the analog laws that'd would be a hell of a find.


I am currently about to start some medical treatments which are a perfect reason to be prescribed marinol. I am pretty excited to try the stuff. Thankyou for sharing the info on smoking it, that is good to know. Obvious next question from any good junky would be: Whos broken them down and banged em? Is IV a viable route?

[Woowoo]

Can you smoke this shit?? What happens if you sprinkle some of this magical dust on ditch-weed, do you instantly have super-killer kind bud that would knock superman down??

Seeing that commercial pot sells for $1000 per elbo, and good bud sells for $4000 per elbo, some magical way to turn the commercial into the good stuff would be priceless. It's the pothead's equivilent of the alchemist's dream... turning lead into gold!

Very interesting indeed!

[Hammilton]

I thought about ordering some WIN-55,212-2 since it's well priced for 3 doses.

oddly enough, I'm not interested in it to get high. I have access to PET-scans and fMRI's for the next two weeks, and want to see how this works on the brain differently from normal THC.

Hopefully I'll be able to get some screen shots available here at opiophile.

[TappyTibbons]

question, would a chemical like nabitan (Benzopyranoperidine) be "legal" since it is an analogue of dronabinol which is CIII and the analogue act only covers analogues of CI and II drugs

I have read from several forums, and been told by several rc and bulk pharm chem sources that, yes they are legal in this case. It's one loop hole of sorts that would completely cover your ass in court. I bet it wont be long until that loop hole is a brick wall. lol oh and this stuff is of a fairly good price from the source that I got the quote from. 150mg $130 with the dose being so small... thats incredible

[Hammilton]

I don't think any chem houses even required a DEA number or whatever to purchase the stuff. But the DEA has users and legit, but small or proprietary scientists in a bind. What if the court decides to say "he was going to use that stuff so lets punish him as if it's an analogue of natural THC."

it's a precarious position.

[robojunkie]

Since it is synthetic and not a constiuent of cannabis as is and, assuming it isn't scheduled itself, I'm not even sure if it would be considered an analogue chemically. It may however be considered an analogue pharmacologically, if the analogue law has become that oppressive. I mean there are just too many differences in the functionality and alterations in the core ring system. Let's see, for similarities there's the basic partially hydrogenated phenanthroid heterocycle with the 6-dimethyl and the 1,5 RO-functionalities. Then the differences...a 9 aza substitution, a 9 propargyl substitution, the piperidine butyrate ester, the extended oily side chain and the "delta" isomerization. There are enough differences chemically between this and THC/dronabinol or nabilone or any of the other variations in the olefin position or side chain that I can't see how the hardest ass dea lawyer could argue this as an analogue chemically. Didn't they just have to pass a new law just to ban some of the rc's like 5-MeO-DMT and such because of formula differences and so forth? If that's an analogue of nabilone I guess atropines are analogues of coke, our own sympathetic phenethylamines are speed analogues and so on. Wouldn't surprise me though, pretty soon everything will be schedule I except table salt, water and soda water, but only with CO2 content below 3%!

[Hammilton]

yeah, but look at some of the case law. There's been stranger things to happen in our legal system.

I don't personally think it's an analogue, and even if it were, I think that there's enough of a case that since synthetic THC is C3, that this can't be covered.

What worries me is the attitude of judges and jurors and the sorts of legal gymnastics they're willing to perform to put another doper in prison.

[oxydose]

this stuff called hash oil in the early-mid seventies.

Its extremely easy to make, read up.

[smartguy]

thats very interesting

[smartguy]

Its extremely easy to make, read up.


how easy is it

[antigonemuse]

how easy is it


very easy.... once again.... how many posts you gonna grace us with in a two minute peroid.... slow down.... we like quality here, not quantity (just like our drugs)

[Hiems]

what company is this chem available from anyone mind sharing?

[Synack]

what company is this chem available from anyone mind sharing?

Here (http://www.google.com/search?q=CP+55%2C940+purchase&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a)

aka.

UFTSE :D

Smart boy: Use the http://forum.opiophile.org/images/gnome/buttons/edit.gif button next time! :p

[elegua]

So...um...any official feedback on auto bio-assay? I'm eagerly awaiting a report.

Regarding cannabis-as-food, it's my preferred method of ingestion, but no doubt it's really got some nasty potential (pun not intended). It was the cause of my first and second to worse bad trip of any sort -- just sheer misery and panic with thoroughly uncool open-eye hallucinations and terrorizing thought-spirals. Agh. Even after that one, I had two more bad or at least highly uncomfortable experiences before I knew to test a tiny amount of any large batch. I like brownies, and garlic bread preparations, but by far my favorite is something like traditional Indian bhang -- basically a chai-type brew made of tea, whole milk, various spice mixes (I have three different recipes), with the cannabis pounded in a mortar with heated milk. So there's no leaves or budlets floating about, it's all fluid, tasty, and not quite as long-lasting as brownies. Of course I only do this type of thing when visiting Amsterdam.

I recall one night, long time ago, where several friends were over at my house. One girl who happened to already be hungry was sitting by the chopped brownie bits while we were all playing cards. I had arranged it so that each 2x2" piece was decently strong, and even a serious daily user should take two at most. The girl knew what was there, but after a while she forgot the details and without thinking about it, easily ate about 5 of them. When she realized what she did, she was a bit nervous, but as an hour passed with only a moderate buzz, we thought things were OK. Then somewhere around the one and a half hour mark, it all hit at once. I've never seen anyone so zonked out in my life. She also needed to be more or less tied down, because she kept going through cycles of being semi-conscious, then would wake up in a state of total panic, and be completely focused on getting out of the house and driving home! So, we got her sister to come over and hold on to her for about 6 hours. Incidentally, she fed half of a brownie to one of my dogs...I've never seen a dog so zonked in my life. He was standing, facing a wall, watching it intently, while leaning slightly to the left until he fell over -- never taking his eyes off that spot on the wall.

Speaking of analogue laws, I'm still kind of amazed that no matter how many times various RC's have been scheduled, including plenty of chemicals that either aren't that entertaining or are unpleasant or otherwise have not that much abuse potential, DPT has remained unscheduled, even though it has been known, used, written about (especially in regards to that church that uses DPT as its sacrament/host) far more than most RC's. The church is so small that I doubt it is a religious freedom thing (religious freedom hasn't stopped them from banning things before)...ah, who knows, I am certainly not complaining!