Will I withdrawal if...?

[Mouzin]

I have been snorting 4 Opana ER 40mg a day for the last few months. That is a total of 160mg of oxymorphone a day. I am starting a new job and want to stop snorting the Opana. It will be difficult too keep up all the work it takes to prepare the lines to take with me all day and escape to the bathroom every few hours to get a fix. I am planning on starting to just eat the pills the way I am supposed to. I will still take 4 40mg pills a day. Will changing the method I have been using them cause me to have withdrawals? I know that the bioavailability is different when snorted vs swallowing but how different is it? If I will withdrawal will it be minor or will it be nearly full blown withdrawals? I start the new job on Tuesday the 29th, will I feel better by then? Thanks for any help I can get.

[OxyContinuously]

Hi Mouzin ;-)

In short, no, you will not go into withdrawal. You are wuite right when you say that the bio-availability of oxymorphone is not too hot when taken orally, and is a lot more efficient snorted, etc.

As long as you are taking the same "milligramage" every day (you could even go a bit lower; the trick to tapering is to reduce your intake by one-third, every three days...in other words, you take 160 a day; you would take 120 for three days, then on the fourth take 80, do that for three days, then reduce the 80 by one-third, and so on and so forth until you reach a lower intake--I know you don't intend on tapering, I was just including this just in case you were interested, and by the way this is the medically accepted way to taper off of a narcotic painkiller with absolutely NO WD ;-)

So anyway, to answer your original question, as long as you keep your intake in the same range, you will have no wd even if your preferred method is snorting, but you eat it from now on. The only thing you 100 percent WILL notice is that the high is not as intense, but that's okay i guess, as long as you don't get sick, which you won't!!

Hope this helps
later
peace out

Oxy

[Woowoo]

I agree with the previous comment and I'll even add, that you might end up being more high from your pills than before. You won't have the quick-hard rushes you get from snorting it but in terms of a longterm high you may find that are blasted.

So that's a FAR CRY from going to WD's, you might actually end up gettiing off MORE!! The oral route will give you a mild high that lasts for hours and hours. And if you eat enough, it's not so mild at all.

--Woowoo

[Mouzin]

I just thought that if I was snorting them and that out of the 160mg I was actually getting 50 percent of that in my blood stream and I then switched to eating them and only 10 percent was getting into my blood stream that this would be a big enough difference to feel a little sick. Does how I explained that make sense? Now, I know that the numbers I gave are not the exact bioavailability of oxymorphone I was just using those numbers to illustrate my point.

[OxyContinuously]

I just thought that if I was snorting them and that out of the 160mg I was actually getting 50 percent of that in my blood stream and I then switched to eating them and only 10 percent was getting into my blood stream that this would be a big enough difference to feel a little sick. Does how I explained that make sense? Now, I know that the numbers I gave are not the exact bioavailability of oxymorphone I was just using those numbers to illustrate my point.


I get what you're saying. You have to remember that regardless of the bioavailability of the various routes of administration, the bottom line is that your intake is the same, on a milligram to milligram basis--- so even if snorting gets "more of a kick" than eating cause of bioavailability, that's secondary cause the TOTAL is the same. So whereas snorting getsthe 160 into your system more efficiently than eating, you have to remember that eating gets the same amount into you, albeit less efficiently.

And WooWoo's right---> if you eat enough you'll get an all-day type blasting high; oxymorphone is potent stuff!!

take care
later
peace out

[doctor diesel]

Yeah Oxy, but, if, for the sake of argument, oxymorph is, say, 60% orally bioavailable, doesn't that mean that your blood system is not ultimately getting 160mg, but is getting 160x60%, which is 96mg?
I think that's what Mouzin is getting at.


Doc

[OxyContinuously]

Yeah Oxy, but, if, for the sake of argument, oxymorph is, say, 60% orally bioavailable, doesn't that mean that your blood system is not ultimately getting 160mg, but is getting 160x60%, which is 96mg?
I think that's what Mouzin is getting at.


Doc

Hmmm....Doc, that is a very good point...you know what? Actually you gave me a very good idea for a suggestion.

How about this: indeed Doc, snorting is more efficient, and you know what just dawned on me? He could probably get away with eating the 160, OR just to be safe and satisfied, he *could* up the oral dose by maybe an additional 20 to forty migs jsut to make up for the "inefficiency of oral."

I didn't look at it like that---I am positive 160 orally will be jsut fine, but for the "kick" that he felt snorting, he probably should up it a bit.

good one...but hey that's why your the Doctor!! (jokin, jokin ;-)


later

Oxy

[doctor diesel]

I am indeed The Doctor!
I've found, with tapering, that you can take considerably less than your normal dose-of-choice without getting WDs. Like, back when I was a codeine junkie (aah, sweet), taking only 50% of my normal getting-high dose was plenty adequate to keep away the heebie-jeebies.
So like you say, Oxy, our man is going to be just dandy on that theoretical 96mg, and he really shouldn't be looking to get at high at his new job anyway.


Doc.

[Black_Pony]

I agree with the doctor. I think you will feel noticeably uncomfortable when you switch from insufflating to oral. You shouldn’t experience full blown W/D’s as you say but I imagine you will definitely notice the difference. By the 29th, your body should be fully adjusted. You should be just fine, but don’t count on getting high or blasted all day unless you increase your dosage.

[OxyContinuously]

I agree with the doctor. I think you will feel noticeably uncomfortable when you switch from insufflating to oral. You shouldn’t experience full blown W/D’s as you say but I imagine you will definitely notice the difference. By the 29th, your body should be fully adjusted. You should be just fine, but don’t count on getting high or blasted all day unless you increase your dosage.


You guys are right, and I can personally relate to that. Example: I like OC and usually sniff it. Well, just so happens that my man has had a recent influx of the Teva footballs (Roxi* where are you dear? I know you feel my pain, LOL jk, jk ;-) and you guys prob. know that they are so "abuse proof" that even crushing the hell out of them with a grinder I use for cocaine, made especially for coke, to get the powder as fine as possible really didn't help much, from an absorption standpoint.

So, seeing as I don't shoot stuff, and "browning" is just not my cup of tea, my only option left was orally. If I remember correctly, the sniffed 40mg was prob. equal, orally, to a dose of about 60 milligrams--> considerably more, by a factor of 50 percent...I am talking "rush-wise" remember. Also remember that oxycodone and oxymorphone are two different animals. Oxycodone happens to have a very very high oral bioavailability (80 percent or more) and snorted this sinks to maybe 50 - 70 percent. Even so, I had to increase my dose.

So I can imagine that for oxymorphone, with a considerably less oral bioavailability (10 percent as opposed to around 40 percent insufflated) he would logically have to up the eaten dose a bit.


sorry if I confused anyone, but I want to be clear and expalin myself, so I don't unintentionally mislead anyone ;-)

later

Oxy