sorry, I'm starting yet another thread

[jwalm]

-i have been ingesting 50-80 mg of methadone for the last 10-12 days or so (i get high and feel good all day on as little as 60mg of methadone)

-now from what I understand methadone sort of blocks other opioids from attaching to your receptors, thus not allowing you to get the normal/full effects from other opioids while on methadone

-now during this period of 10-12 days that I have been under the influence of methadone, I have started IVing Hydromorphone- i just IVed 12mgs of Hydromorphone and did feel a little rush, but nothing like how most people speak about how great the Hydromorphone rush is

-do you think my lack of awesome effects from the Hydromorphone is because I already have methadone attached to my receptors and the methadone is blocking most of the Hydomorphone from attaching to my receptors?

-also, do you think that if my receptors were completely free of all opioids (especially methadone) that me IVing 12mg of Hydromorphone would provide me with a much better rush and after effects than before when I had methadone attached to my receptors and I IVed Hydromorphone?

-and also, do you think that if I IVed 12mg of hydromorphone with my receptors totally free of all opioids/opiates that there is the potential of me overdosing?

I would really appreciate it if multiple people answered all the questions i asked in this post:D

thank you:)

[soulman]

yes the meth is keeping you from experiencing the full effects of a 12mg dilly slam!!!
that answer should pretty much answer all your questions, because they were all almost the same question, just phrased differently.:)
---peace---
da soulman
p.s. since I don't know you or your tolerance it would be impossible to tell you if you would o.d. on 12mg. of dillies! sorry.
hope that helped ya a lil' bit
and if i was you i would try not to do too much of the meth., for rec., for too long- worst w/ds of all opis!!
that's why people on meth. maintanence programs are on em' for like 20 yrs. the kicking part is hell for like 30-45 days!

[Woowoo]

-do you think my lack of awesome effects from the Hydromorphone is because I already have methadone attached to my receptors and the methadone is blocking most of the Hydomorphone from attaching to my receptors?
Yes.
-also, do you think that if my receptors were completely free of all opioids (especially methadone) that me IVing 12mg of Hydromorphone would provide me with a much better rush
Yes.
and also, do you think that if I IVed 12mg of hydromorphone with my receptors totally free of all opioids/opiates that there is the potential of me overdosing?
No.

I say that because even somebody with no habit whatsoever is unlikely to overdose on 12mg of dilaudid. I'm sure it's possible, but the LD50 for dilaudid is probably much higher than 12mg.

I would start to worry around 20mg and higher. Even then, I've seen somebody shoot 10 K4's before (40mg) and have heard tales of much larger doses than that--but of course these people weren't "totally free of opiods" by any stretch.

[oxydose]

-i have been ingesting 50-80 mg of methadone for the last 10-12 days or so (i get high and feel good all day on as little as 60mg of methadone)

-now from what I understand methadone sort of blocks other opioids from attaching to your receptors, thus not allowing you to get the normal/full effects from other opioids while on methadone

-now during this period of 10-12 days that I have been under the influence of methadone, I have started IVing Hydromorphone- i just IVed 12mgs of Hydromorphone and did feel a little rush, but nothing like how most people speak about how great the Hydromorphone rush is


Man I OD'd off taking 100mg, 70, 60, 50, 50 of done (i mean first day, 2nd, 3rd, etc. in that order) and then on the final day (had taken 50mg) I banged the better half of a 80.

methadone keeps stacking and stacking, if you've been enough to get high from for that long I must really advise you against banging anything man, atleast cut out the methadone and wait a day or two.

when I mean I OD'd it just wasnt a hospital visit with a Narcan shot, my kidney fully failed, liver was so saturated with opiates it was about to go out, and of course full resp destress, not to mention the 4 minute flatline and 4 day coma.

so yeah, cut the shit, or atleast dont be fixin/eating dones all by yourself, make sure someone is there to watch you.

[jwalm]

I've been ingesting up to 100mg of methadone on occasion for over three years, I'm no newbe when it comes to opiates, i know how much methadone i can handle:D

and your post confuses me....

-if someone has been dosing on methadone for a few days then IVs some other opioid-the chances of ODing from the opioid he/she slammed is even less likely than if he/she had not been taking methadone for the few days prior-this being because the methadone attaches to the opioid receptors in the brain and blocks other opiods from attaching, thus not resulting in an OD (at least this is how i understand it)

of course there are always different variables to my above statement-ex. person was dosing on very low amount of methadone for days prior, then IVed a hefty amount of opioid for their tolerance--etc.

[Diacetyl]

methadone "eh"?


Yes, you wasted taht 12mg dilaudid.

*cries*

that pooooooor dilaudid

Methadone completely blocks your opiate recepters from reuptake and creates a "lock" on them so nothing can bind while the methadone is still in your system.

that was painfull to read, good luck... gotta wait a good while till the methadone wears off before you try and dose with another opiate.


please dont waste anymore of that precious dilaudid...its a sin.

[jwalm]

methadone "eh"?


Yes, you wasted taht 12mg dilaudid.

*cries*

that pooooooor dilaudid

Methadone completely blocks your opiate recepters from reuptake and creates a "lock" on them so nothing can bind while the methadone is still in your system.

that was painfull to read, good luck... gotta wait a good while till the methadone wears off before you try and dose with another opiate.


please dont waste anymore of that precious dilaudid...its a sin.

how long do you think i need to wait till i can dose on another opioid after doing methadone and feel full effects of the 2nd opioid? are we talking days? like waiting as long as it takes to start withdrawaling from methadone?


I just recently acquired a grip of 4mg dillies and everytime I have slammed them I had dosed on methadone about 24 hours before. I have yet to experience that rush that yall speak so fondly of. Do you think I simply just need to wait 2-3-4 days till after my last dose of methadone to try the hydromorohone again?

[Diacetyl]

how long do you think i need to wait till i can dose on another opioid after doing methadone and feel full effects of the 2nd opioid? are we talking days? like waiting as long as it takes to start withdrawaling from methadone?


I just recently acquired a grip of 4mg dillies and everytime I have slammed them I had dosed on methadone about 24 hours before. I have yet to experience that rush that yall speak so fondly of. Do you think I simply just need to wait 2-3-4 days till after my last dose of methadone to try the hydromorohone again?

a full 48 hours after the done should be long enough.. methadone half life is 24-36 hours so after 48 hours you can be sure enough of it is out of your system to "free your recepters".

[oxydose]

I've been ingesting up to 100mg of methadone on occasion for over three years, I'm no newbe when it comes to opiates, i know how much methadone i can handle:D

and your post confuses me....

-if someone has been dosing on methadone for a few days then IVs some other opioid-the chances of ODing from the opioid he/she slammed is even less likely than if he/she had not been taking methadone for the few days prior-this being because the methadone attaches to the opioid receptors in the brain and blocks other opiods from attaching, thus not resulting in an OD (at least this is how i understand it)

of course there are always different variables to my above statement-ex. person was dosing on very low amount of methadone for days prior, then IVed a hefty amount of opioid for their tolerance--etc.

I'm not quiet sure your right about that man, as Methadone doesn't work like bupe, it doesn't fully block anything, if it did then how could you get off on methadone each day? it may weaken but doesnt fully block,

I'm not quiet sure if i'm right either man, but ask in the methadone forum, and heed my warning that mixing methadone with other opiates/CNS depressants isnt safe by any means.

I just know what happened to me, and I wasn't naive either man. I've been on pills for the better part of 6 years now, IV user for the last two. I didnt think id be the person who OD'd, it happens and Id just like for you to heed my warning about mixin the done'

[nick]

man 'done is an opioid.If you take dope on top.....you're upping your chances of an od.

'done ain't subs.


Be careful.


Very careful.

[oxydose]

^ yeah what he said

[greasy_bear]

When I was on MMT (80mg/day) my tolerance for dope was sky high. To get a rush I could feel, I'd have to do twice as much dope as before.
Trying to get off on another opioid while on 'done is a waste in my opinion and according to many here, pretty dangerous (something I hadn't realized).

[vanilla_mlkshake2007]

For Me Believe it or not injecting 10 of the 4 milligram dillies a day was very common the last two years of my life.I never came close to o.d.ing on Dilaudids.I do have a monster tolerance also.I use 620-740 milligrams of Avinzas (morphines) a day.I would do both of the drugs by IV use and I never even got a lil withdrawals when I stopped using It's just that I am a morphine girl.
I expect most of you will think I am exaggerating or maybe that I was getting the wrong drug or maybe I was missing my hits,but diaudids are very easy to inject.Even me who has lil or no veins found it very easy.
I just don't find doing D's are all theyt are made out to be.Yeah hell it's a great rush.Totally different from Morphine,but alot more expensive as I pay 10 bucks for a 120milligram morphine.it was costing me $50 bucks or more a day doing 10 dillies,so I'll stick with morphine.I know alot of you will think I'm totally whacked but that is just what I like.
How I quit doing that amount of D's for 2 years without noticing the withdrawals was just upping my morphine a bit here and there.Honestly I was lucky and it didn't phase me at all.
Now when I run outta morphines I get the shits , sneezys, sweats,feel like I am gonna die and count the hours till I get something.Mostly I try to score once monthly and spread it out so I don't have to w/d at all.Just my opinion.

[oxydose]

vanilla, reread what I said. I've done the same as you (40-48mg) dill a day for long periods of time with no where close to a OD. I didn't say dill alone was dangerous (ok it is to a untolerent person, but w/ a tolerence well ya know). I said taking daily methadone doses expecally ones large enough to get you off and then shooting up is dangerous, Methadone and OC IV did it for me, and I suspect done' and HM IV would do about the same.

[nick]

Look guys it's very simple.If you take 'done and start ivi'ng anykind of dope on top...........it's dangerous.


I'm just saying,TAKE CARE.


Just the other day some guy(sorry can't remember the name) was here telling his sad tale of od'ing in similar circumstances.

Take care and realise life is a one way trip.