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View Full Version : Methadone to Subs Q


tptptp
04-18-2007, 01:05 PM
So someone here apparently wants to go from 160 or 165(cant remember exactly) mg methadone/day to subs. I told them I *think* you can go from methadone to using straight opiates for a while then go to subs, cause obviously you cant go from that high a dose of methadone to subs off the bat.

A)Is it correct that you can go from a mega dose of methadone to using a straight opiate for a little bit so you can switch over to subs?

B) The person said theyve been busted and cant risk getting any straight opiates anyways, cause the only connects they have are to H. I recall reading here before about doc's giving their patient some oxy's or something in between a switch before. So is this just a freak occurence or is it a possiblity that a doctor, seeing that he wants to switch would prescribe him something for a few days to switch over.

Hammilton
04-18-2007, 02:12 PM
well, you can definitely do it, but there's the obvious question of how long to wait between dosing done and suboxone.

I'd taken 60mg (less than half) for two or three days. Then, if you can, take just enough oxy and Immodium that you're not on the can 24/7.

I went from 80mg daily to 20mg one day, then nothing for the next three days. well, not enough ultra-short acting narcotics to feel. I sucked on a fentanyl patch, some Ativan (1 or 2mg total) and loads of Gabapentin.

After two days of sucking on the 25ug/hr Mylan patch for two days (with it on me for 8 hours as well). I took the 1mg of ativan on two of those days to sleep.

If you can, get 1800mg of Gabapentin- when I took 900mg on the third day of "'done sobriety," withdrawal signs were COMPLETELY OBVIATED!!! It was nothing short of parting the red sea. Lyrica would probably do the same thing, but it's scheduled, and is damn near the same thing.

I would wait until the 4th day of taking NO methadone, and at least 28hours post short-acting narcotic dosage.

I took it on the third day (4mg) without methadone and 24 hours since I sucked on the fentanyl. I ended feeling WAY in withdrawal for the rest of the day. The next day I was damn near perfect though, and I might have been if I took some more Suboxone, I dunno.

I don't think this will be too hard.

Since this is such a high dose of methadone, I really think you need to wait longer than usual. There may be some things you can do to speed it up, though

Methadone is built up in the liver, uncongjugated, over time with repeated doses. If you can do something to "wash out" your liver, you could probably shorten the half-life and be able to dose age sooner.

N-Acetyl-Cysteine (NAC) might be of some help, and I think milk-thistle or whatever it's called would help.

Taking things like Barbituates, and other Liver enzyme inducer (the opposite of what Cimetidine does). There's a list somewhere of what speeds up Liver enzymes, and some of them are rather simple. Lots of anti-epileptics I think.

not benzos though- they're worked on by the same Cytocrome P450 (I think) that Narcotics are eaten by.

Just some advice.

mikells43
04-18-2007, 08:39 PM
well said. the recomendation for switching over is 30mgs and being stable on 30mgs for a period. then going into withdrawls from that based upon when ur first bupe dose is. i dont think a doc would do that for a person, jus twrite them a script so they arn't dope sick. i dont think treating dependence is one of the criteria for perscribing oxys but thats just me lol. it can be done with less pain u just have to be resourceful, and as far as buying on the street if u are being watched, then go somewhere else and cop. thats what ive done before andit works. im stable on bupe and happy and only have control over one person and thats me:). take care

Hammilton
04-19-2007, 03:27 PM
i've had a doc write me a script for Oxy for the interim period between methadone and Bupe. i got a whole 20mg a day for three days, but it worked fine, even if I felt like shit