Creating a new forum about chemistry

[kingdxm]

To Jachy or whomever it may concern: has anybody thought of starting a new forum about chemistry of opiates of other such things that have to do with chemistry. I love to talk about pharmacology and chemistry and was wondering if it would be possibe to start a discussion board about it. What do you think?

[Diacetyl]

There are alot of forums on the web specifically designed for chemistry discussion. Never found one specifically related to opiate chemistry though, it might be worth a go.

[SuperJunky]

Theres a whole opiate chemistry area here, why would we want to break it off into it's own site?

[kingdxm]

I mean talk about some serious chemistry.:rolleyes:

[nick]

I mean talk about some serious chemistry.:rolleyes:

Everytime there's a chem discussion here,it ends up in a brawl.

[chemboy7]

Everytime there's a chem discussion here,it ends up in a brawl.

Yep, problem is we don't have Woods to put us all in our place anymore. :D

[In The Wind]

There ia an entire sub-forum dedicated to chemistry on the board. I'd say that if you had something you wanted to discuss, post away..

[SuperJunky]

There are people here that really do know there shit. I'm sure if a real chemistry discussion came up robo would keep the bs out,so if you want to discuss some seriouse chemistry thats more than possible. Just start a new thread...

[nick]

Yep, problem is we don't have Woods to put us all in our place anymore. :D


Oh bro,you just know Woods was part of the problem-not the solution.


and last time we had a chem discussion............remember?



Oh and shouldn't you be looking after your chickens?

[jacky]

heres some serious chemistry discussion.

lets get moving on researching some of the active opioids found in nature. other active compounds are of interest as well, especially analgesic type compounds and anything dopaminergic.

a small research group made of a dedicated opiophiles can break off and create our own limited private discussion forum.

we can take it offline...or make another website....and call ourselves "rouge research".

at rouge research it is our mission to injest/bioassay possible/purported/debated opiate/opioid material.

first study project is the possible psychoactive opium alkaloid noscapine, which is rumored to be similiar somewhat to dxm in effect.
I dont think the material is controlled, and is possibly an OTC substance in other countries.

in its pure form it could be described as an organic compound for plant research studys.


feel free to discuss whatever chemistry interests you, as for the serious end of it kingdxm, I am afraid that serious is as serious can....most opiophile here at this website have limited organic chemistry knowledge at best, including me.
I can keep up with names, and know some general activitys associated with the various known psychoactives,....but when people start talking about specific chemistry, structural anomalys, structural integrity, synth routes, and novel/exploratory chemistry discussions....I am generally at a loss.

if some "hive" like group of individuals started more arcane type of research discussions here one opiophile I woiuld be stoked.

the problem is most people just want to make heroin with any acetyl sounding name substance they can get their hands on, and the real chemistry knowledgeable folks get sick of handing out spankings.

there are alot of areas that I am interested in isoquinoline chemistry...both for the opioid interests, the opioidopamine interests, and serotonergic quest.....

but this noscapine stuff is really interesting at the moment.
opium alkaloid, with mystery effects,.....someone get me a pile of 98% pure powdered noscapine and a scale!

[doctor diesel]

What effect(s) is noscapine supposed to have, Jacky?

Doc

[Hammilton]

i'd be down for this.

you can check out the noscapine clearing house: www.noscapine.org

or visit http://www.pcref.org/noscapine_sources.php to find some online sources of it

[robojunkie]

heres some serious chemistry discussion.

lets get moving on researching some of the active opioids found in nature. other active compounds are of interest as well, especially analgesic type compounds and anything dopaminergic.

a small research group made of a dedicated opiophiles can break off and create our own limited private discussion forum.

we can take it offline...or make another website....and call ourselves "rouge research".

at rouge research it is our mission to injest/bioassay possible/purported/debated opiate/opioid material.

first study project is the possible psychoactive opium alkaloid noscapine, which is rumored to be similiar somewhat to dxm in effect.
I dont think the material is controlled, and is possibly an OTC substance in other countries.

in its pure form it could be described as an organic compound for plant research studys.


feel free to discuss whatever chemistry interests you, as for the serious end of it kingdxm, I am afraid that serious is as serious can....most opiophile here at this website have limited organic chemistry knowledge at best, including me.
I can keep up with names, and know some general activitys associated with the various known psychoactives,....but when people start talking about specific chemistry, structural anomalys, structural integrity, synth routes, and novel/exploratory chemistry discussions....I am generally at a loss.

if some "hive" like group of individuals started more arcane type of research discussions here one opiophile I woiuld be stoked.

the problem is most people just want to make heroin with any acetyl sounding name substance they can get their hands on, and the real chemistry knowledgeable folks get sick of handing out spankings.

there are alot of areas that I am interested in isoquinoline chemistry...both for the opioid interests, the opioidopamine interests, and serotonergic quest.....

but this noscapine stuff is really interesting at the moment.
opium alkaloid, with mystery effects,.....someone get me a pile of 98% pure powdered noscapine and a scale!

Yeah, Jacky this is exactly what I was thinking of at one point as well...a chem forum dedicated to the heavier theoretical/research/experimental type stuff, but locked down or, even better as you said, only open by invite. This would be really cool and it would have a more "scholarly" (sorry, best word I can think of right now) feel that I think would discourage the ego battles and personal tit for tat nitpicking and arguing for the sake of arguing. Hell, science should be about all of those with something to contribute collaborating and discussing, with the outcome that everyone's knowledge base grows significantly.

Example: I know a pretty good deal for my relative professional experience level (2nd year phd student) in the synthetic methods/retro-syn analysis and design areas but far too little about biology and biochem and neurology and natural products/effects. A cool group with a diverse knowledge base would quite likely produce some insightful ideas and maybe even some actual theoretical and even literal pharmacological developments! I'm all for this and I definitely think it should be a private type/invite sort of thing. Definitely set it up Jacky, I'll definitely contribute here...

Also, I can't emphasize enough how important the idea of a wider scope is. Not just the pure synthesis and design, but structure-activity ideas, natural material potentials and possible modifications, etc. There are a number of regulars here with a range of expertise in different areas that could do some awesome hypothesizing/discussing/theorizing/experimenting/etc. Some have posted here...

Any reason we couldn't have it here Jacky? No soliciting issues or conspiracy to manufacture C-I and II analogues type shit, therefore no problem for the site, especially if private, right? Or wrong? Other issues I may not be aware of?

[drugsaregood]

heres some serious chemistry discussion.

lets get moving on researching some of the active opioids found in nature. other active compounds are of interest as well, especially analgesic type compounds and anything dopaminergic.

a small research group made of a dedicated opiophiles can break off and create our own limited private discussion forum.

we can take it offline...or make another website....and call ourselves "rouge research".

at rouge research it is our mission to injest/bioassay possible/purported/debated opiate/opioid material.

first study project is the possible psychoactive opium alkaloid noscapine, which is rumored to be similiar somewhat to dxm in effect.
I dont think the material is controlled, and is possibly an OTC substance in other countries.

in its pure form it could be described as an organic compound for plant research studys.


feel free to discuss whatever chemistry interests you, as for the serious end of it kingdxm, I am afraid that serious is as serious can....most opiophile here at this website have limited organic chemistry knowledge at best, including me.
I can keep up with names, and know some general activitys associated with the various known psychoactives,....but when people start talking about specific chemistry, structural anomalys, structural integrity, synth routes, and novel/exploratory chemistry discussions....I am generally at a loss.

if some "hive" like group of individuals started more arcane type of research discussions here one opiophile I woiuld be stoked.

the problem is most people just want to make heroin with any acetyl sounding name substance they can get their hands on, and the real chemistry knowledgeable folks get sick of handing out spankings.

there are alot of areas that I am interested in isoquinoline chemistry...both for the opioid interests, the opioidopamine interests, and serotonergic quest.....

but this noscapine stuff is really interesting at the moment.
opium alkaloid, with mystery effects,.....someone get me a pile of 98% pure powdered noscapine and a scale!

I'll be a guinea pig for rogue...Just don't give me any of that placebo crap. :P

[CSiiSEQ]

first study project is the possible psychoactive opium alkaloid noscapine, which is rumored to be similiar somewhat to dxm in effect.
I dont think the material is controlled, and is possibly an OTC substance in other countries.

in its pure form it could be described as an organic compound for plant research studys.

but this noscapine stuff is really interesting at the moment.
opium alkaloid, with mystery effects,.....someone get me a pile of 98% pure powdered noscapine and a scale!

Noscapine is really quite easy to get. It is currently commonly being used off-label in the treatment of prostate cancer as well as prevention/tx of metastasis. The FDA considers is OTC- it was approved throughout most of the world as a cough suppressant many years ago. There are foreign compounding pharmacies that do ship Noscapine to the US- there is a big one is Israel - that is the big source for US prostate ca patients. There are also others in Holland, Spain and one other place I can't think of atm.

In addition to its sigma receptor activity (effects reversible by s-selective rimcazole, it also has a very interesting anti-tubulin effect which is responsible for its use in ca research. The mechanism of action in cancer treatment seems to be extremely similar to the taxanes Docetaxel & Paclitaxel.

[kingdxm]

I am willing to discuss chemistry in any way you guys and gals want, whether it be a forum, posts, whatever. I always try to keep the layman in mind so they can began to understand as well. I belong to another site that talks about drug chemistry and many of the people think they fucking know everything(including the moderators) and when you try to discuss something new they insult you and are close minded. So I rarely post on that site. I don't claim to know everything about chemistry as I am a continual student of it. I don't much deal with the complex chemical equasions, p-s orbitals, electrn density, or any of that shit you don't really need(unless your an analytical chemist).To me it is like algebra, I have hardly ever used it since I left high school.

[northernstar]

i tried to start some synthesis threads under "chemistry" about 9 months ago-mostly focused on extracting thebaine from p.bresticides and then converting to the Bentley Compounds ( i.e thevinols and orvinols) which are then used by industry to make most of your perscription semi-synthetic opiods. my main intrest was etorphine becuse even a small yeild of this ( say 8 grams) would provide the home user a years supply. i also found a United Nations report on recaptureing thebain fron waste from the production of opiates ftom poppy straw. it went thru about 20 process with tables of yeilds for thebaine...and many of these could be used in home extraction. i cut pasted it into a post becuse i wanted to archive the information should the UN decide to pull the info.
1. i got complaints it was to long and technical and i should only put a link-becuse links are easyer to skip over ......links dont save info tho.
2. bentley compounds are BAD and WAY too chemistry focused for opiophiles....and i should find a chem forum.
3. this site is for "users" and makeing etorphine,ect is only for "dealers".......a user could never want his own stash i guess,lol.
4. i seen book-x, it has good info about this very thing, but no i wont scan it and post from it. that helps alot.

so if this becomes a chem forum, or u start one id be interested. theres alot of focused process info-but in the form of pay-pdf's from sci-reserch companys. if someone wants to help feel free to scan and save. my focus lately has changed to tropane dervitives, but opiates are still a prime intrest of mine.

Does anyone else think these ideas are worth talking about or investigateing?