Dissappointing Oxy experience

[NOMAD88]

Background: SWIM doses 180-200mg hydro at one time 3-4 times a week and as of last few months is not getting much if any euphoria at all.

SWIM first time with Oxy doses 40mg insufflated and another 40mg oral an hour later and notices very minimal effects.

SWIM second time with Oxy doses 60mg oral and another 40mg oral within next 2 hours and NO euphoria noticed. Next morning SWIM doses 60mg oral and still nothing a few hours later SWIM is puking and feels like crap.

SWIM is looking for any theories, explanations, or advice for next time. Thanx

[OxyContinuously]

Background: SWIM doses 180-200mg hydro at one time 3-4 times a week and as of last few months is not getting much if any euphoria at all.

SWIM first time with Oxy doses 40mg insufflated and another 40mg oral an hour later and notices very minimal effects.

SWIM second time with Oxy doses 60mg oral and another 40mg oral within next 2 hours and NO euphoria noticed. Next morning SWIM doses 60mg oral and still nothing a few hours later SWIM is puking and feels like crap.

SWIM is looking for any theories, explanations, or advice for next time. Thanx

Well, let's see if we can't figure out what went wrong...
You say you like 180 - 200 mg of hydro per "session" to get off? Well, oxy really is stronger than hydro by a factor of about one third to one half. In English, that means that an oral dose of 180mgs of hydro is approximately equal to probably 120mgs, roughly, of oxy. The fact that you take the pills orally, should make this very easy.
I noticed that the first attempt, you snorted 40--which by the way is a pretty good dose, especially compared to hydro. Then the second time you did a total of 100 spanned over a couple of hours. I am surprised you didn't feel anything, frankly.
Here's a couple of suggestions: If you are happy eating your dose, don't get into the whole snorting thing w OC cause it'll just skyrocket your tolerance. I would say to eat around 120mg of Oxy next time, at one time (provided you take AT LEAST 180mgs of hydro AT ONE TIME) and you should experience euphoria. In my expereince, oxy is a smoother, less sedating, cleaner high than hydrocodone. Try that and see what happens.

Later dude

Oxy

[Diacetyl]

Some people lack a certain enzyme to convert opiates too morphine in the body.

Or maybe you have a natural tolerance.

Try some lady H and see if you get anything, if not, you're out of luck I'm afraid :o.

[OxyContinuously]

Some people lack a certain enzyme to convert opiates too morphine in the body.

Or maybe you have a natural tolerance.

Try some lady H and see if you get anything, if not, you're out of luck I'm afraid :o.

but Oxy doesn't get converted to morph.

[Diacetyl]

but Oxy doesn't get converted to morph.

All opiates convert to morphine in the liver.

[OxyContinuously]

No they don't, bro. Oxycodone turns into nor-oxycodone, oxymorphone, and related others---not morphine, though.

[Diacetyl]

So it is, my mistake.


My professor taught me lies . :mad::mad::mad::mad:


Found this just now :

Oxycodone: The mean absolute oral bioavailability of oxycodone in cancer patients is about 87%. In vitro, oxycodone is about 45% bound to human plasma proteins. Oxycodone is metabolized in the liver. A high portion of oxycodone is N-dealkylated to noroxycodone during first-pass metabolism. Oxymorphone is formed by the O-demethylation of oxycodone. The metabolism of oxycodone to oxymorphone is catalyzed by cytochrome P450 (CYP) 2D6. Free and conjugated noroxycodone, free and conjugated oxycodone, and oxymorphone are excreted in human urine following a single oral dose of oxycodone. Approximately 8—14% of the dose is excreted as free oxycodone over 24 hours after administration. Following a single, oral dose of oxycodone, the mean +/- SD elimination half-life is 3.51 +/- 1.43 hours.

[NOMAD88]

Forgot to mention the second time dosing oxy(100mg total) SWIM dosed around 130mg of hydro earlier that day possibly raising the tolerance effecting the euphoria??? Another concern is the vomiting after taking only 60mg oral but having no ill effects after the higher dose of 100mg the day before. Thanks for the advice OxyCon

[OxyContinuously]

So it is, my mistake.


My professor taught me lies . :mad::mad::mad::mad:


Found this just now :

Oxycodone: The mean absolute oral bioavailability of oxycodone in cancer patients is about 87%. In vitro, oxycodone is about 45% bound to human plasma proteins. Oxycodone is metabolized in the liver. A high portion of oxycodone is N-dealkylated to noroxycodone during first-pass metabolism. Oxymorphone is formed by the O-demethylation of oxycodone. The metabolism of oxycodone to oxymorphone is catalyzed by cytochrome P450 (CYP) 2D6. Free and conjugated noroxycodone, free and conjugated oxycodone, and oxymorphone are excreted in human urine following a single oral dose of oxycodone. Approximately 8—14% of the dose is excreted as free oxycodone over 24 hours after administration. Following a single, oral dose of oxycodone, the mean +/- SD elimination half-life is 3.51 +/- 1.43 hours.

Hey, no harm done ;-)

[OxyContinuously]

Forgot to mention the second time dosing oxy(100mg total) SWIM dosed around 130mg of hydro earlier that day possibly raising the tolerance effecting the euphoria??? Another concern is the vomiting after taking only 60mg oral but having no ill effects after the higher dose of 100mg the day before. Thanks for the advice OxyCon


maybe the earlier day dosing affected u a bit. If u haven't already, try and take all 120mgs or so of Oxy at once, that should do ya. Or, wait like 24 hrs if u can, THEN take the OC. THis probably isn't relevant, but if the pills are Contins, make sure you peel off the outer matrix and crush them into paste/powder to defeat the time release.

later

Oxy

[NOMAD88]

Pills were broken up into smaller pieces or chewed but not completely crushed will do next time. thx

[roxi*stardust]

Pills were broken up into smaller pieces or chewed but not completely crushed will do next time. thx
Yes def grind those pills up in a fine powder before dosing, if you don't you may not completely break th time release. Could be one reason why you didn't get evry good effects. If you have a mortar and pestle that is the best way to do it or grind it down like you are going to snort it and then wrap it in a small piece of tissue and swallow it like that.

[lister40]

I would snort like 80mg and see how you feel. My technique is to get a shot glass, smash the OC under the shotglass. It will be in a couple chunks. After that you get a bottle cap and smash the chunks and push down and rotate in a circular motion. That will get it really crushed good. Remember to wipe the powder off the bottle cap :P. From there make your lines and snort, or put it in a capsule (still beats time release) or in a napkin (i usually end up tasting the crap like that).

Get some potentiatiors like cimetidine (works great) take like 400mg of it.. then 120mg of oxy oral or 80mg nasal.

[drugsaregood]

Yes def grind those pills up in a fine powder before dosing, if you don't you may not completely break th time release. Could be one reason why you didn't get evry good effects. If you have a mortar and pestle that is the best way to do it or grind it down like you are going to snort it and then wrap it in a small piece of tissue and swallow it like that.

isn't the time release in the outer nasty coating? ;\

[TokinDerrick]

nope, thats just a color coding to tell the mg's apart easily.

the time release is wax? covered parts of it inside. you break this by smashing it.

pretty much, more ground covered, more ground absorbed.

[AWOL]

I didn't like oxy very much at first either. It's strange, you have to kinda get used to it and figure the shit out.

I still don't like oxy though, overpriced horse shit. (but compared to hydro, hydro is like a wolly mammoth shit)

[greenfox]

Hey, no harm done ;-)

actually you're both wrong. It turns into FOXYcodone.

[insaneike]

isn't the time release in the outer nasty coating? ;\


Nope, the time release IS NOT the coating or the hardness of the pill!!!

The time release will NOT be completely destroyed unless you do an extract on the pills. Yes crushing them is virtually defeating it but it's still there. but its like, well god if anyone doesn't get it just think about it :rolleyes:

and to the original poster try around a 120mg oxy dose. and keep doing 20mg bumps till your good.

[OCfenatiq]

Exactly, just chew it up in your mouth and let it all turn to liquid before swallowing if you can lake it. If not chop it up very fine and eat it up, but this will take longer...

[roxi*stardust]

isn't the time release in the outer nasty coating? ;\
No it is not, and you can stick that OC inyour mouth for a few seconds to get it wet and then take the pills and wipe the coating right off with a paper towel. That coating is just for ID purposes.

1656
Coating removed from 1 tablet.

[mrklean]

IMHO oxy really is a lame worthless drug. I ate 20mg the other day with absolutely zero tolerance I did just about everything I could to potentiate it and the entire experience was beyond worthless. The suggestion to get down with the brown is probably the most logical way to not be dissappointed. I don't personally notice much if any difference between oxy and hydro. When calculating dose I would do as much of one as of the other. The fact that you puked makes me think you had a high enough dose you probably are just realizing that oxy isn't wortha fuck.

[l4l5]

oxy is a godsend for chronic pain patients , ike will say fentinyl is better, my first dose was 10mg whole whaich didnt do anything for feeling wise

2nd time i put the pill into quaters and put em in water for 15 minutes, and daymm 30 minutes later i was fuckered, and my girlfriend called said can u pick me up :mad: damn mess up my high

[blenderqueen]

I agree 1415 it's wonderful for chronic pain at least as a baseline til the B/T pain sets in but I find it very hard to get any buzz off of it. first few times I chewed some up did ok but now chewing 2 20s does nothing much & don't wanna keep going & waste em all as I do need them for pain purposes too. Bear in mind I also take aoubt 150mgs+ of hydro within the morning maybe that's why it' so hard to get a buzz off the oxy I dunno:rolleyes:

[insaneike]

oxy is a godsend for chronic pain patients , ike will say fentinyl is better, my first dose was 10mg whole whaich didnt do anything for feeling wise

2nd time i put the pill into quaters and put em in water for 15 minutes, and daymm 30 minutes later i was fuckered, and my girlfriend called said can u pick me up :mad: damn mess up my high


thats cause fent IS better...

Oxy has never helped my pain for shit. It sucks ass! Keep in mind im in pretty damn bad pain too, and no I don't have a huge toler. oxy and morph are the weaker middle class opis who will indeed help your avg person, but they do fuck all for me.
i mean i can get a ok buzz from roxis(if i take 4 roxi 30s or 3 roxi 30s with 2-3 'done 10s.) but they dont do JACK SHIT for pain. Such a worthless drug in m situation, hell the high isn't too good either. but thats a given, after you try the better opiate oxy n morph suck ass.

and the saying to each is own also comes into play. not to mention everyone reacts different to differ chemicals.

[AWOL]

isn't the time release in the outer nasty coating? ;\ he was just kidding guys. He put a wink in at the end of his post.

;\ = ;)


ya internet n00bs

[roxi*stardust]

he was just kidding guys. He put a wink in at the end of his post.

;\ = ;)


ya internet n00bs
LMAO, I really just wanted to post that picture:p :D :cool: . I have been waiting for someone to say that about the coating. Yes I have issues....:D

[AWOL]

LMAO, I really just wanted to post that picture:p :D :cool: . I have been waiting for someone to say that about the coating. Yes I have issues....:D
I enjoyed the pic a lot :) especially how the coating gets left in the letters. pretty

[roxi*stardust]

I enjoyed the pic a lot :) especially how the coating gets left in the letters. pretty
Purdy isn't it?:D

[l4l5]

well oxy wont give u a nod like other opies will anyway, its more alert, and I love u type hit, thats what it does to me anyway, I never nod on them

[Inspektahdek]

Background: SWIM doses 180-200mg hydro at one time 3-4 times a week and as of last few months is not getting much if any euphoria at all.

SWIM first time with Oxy doses 40mg insufflated and another 40mg oral an hour later and notices very minimal effects.

SWIM second time with Oxy doses 60mg oral and another 40mg oral within next 2 hours and NO euphoria noticed. Next morning SWIM doses 60mg oral and still nothing a few hours later SWIM is puking and feels like crap.

SWIM is looking for any theories, explanations, or advice for next time. Thanx




I'm almost in the same boat, it takes me atleast 150mg hydro to get something out of it and thats usually the only thing I can get readily available at this time. I'm on Fentanyl and percocets from my back surgery but you can imagine how fast those go with the tolerance I have. Right now I'm on tramadol maintenance

[NOMAD88]

Whats tramadol maintenance? SWIM is up to 200mg doses now so you're a little bit behind... SWIM just went through a script of 100 10mg norcos in 6 days. SWIM should switch to OC's cause the tylenol makes the liver/stomach ache/burn but doesn't have a consistent connect. SWIM is baffled by the puking when only dosing 60mg and somewhat hesitant to take more than 80mg at a time. Any insight on that?? Thanks for everyone's advice:)

[L0VE]

same thing happened to me when I had a high done tolerance but it I just kept with the ocs and finally felt the amazing high =).