Dental Implant Administers Drugs

[alowishus]

Dental Implant Administers Drugs

http://blog.wired.com/gadgets/images/6778_2020783011.jpg (http://blog.wired.com/photos/uncategorized/6778_2020783011.jpg)

Researchers are developing a dental implant that administers prescription drugs in small doses over continuous periods. Dubbed "Intellidrug," the implant would be placed inside a pair of prosthetic molars and would release dosages to be absorbed into the mouth's mucous membranes. Ideal for chronically ill patients with large prescription regimens as well as those with mental impairment, the Intellidrug would allow the patient to maintain consistent levels of the drug in the bloodstream. The prototype will be displayed on Feb. 27 at the MedTec trade fair in Stuttgart and will undergo clinical testing later this year.

http://www.gizmag.com/go/6778/

[HistoryofMadness]

Damn controlled controlled substances. All these 'smart drugs' (ref smart bombs) are going to present a real challenge to the junky that isn't adaptable.

[Euphoricgirl]

I have truly heard it all now.

[superman]

hahaha, that's fucking lame!

what ever happened to the good old days when you could buy a bottle of morphine solution and treat your own goddamn pain?

next they'll have CP patients going to a clinic daily.... oh wait, that's already happening isn't it?

[alowishus]

A friend of mine has had the morph pump in her, well 3 of them, the 1st didn't work, although they said it was just her getting used to it....:rolleyes:
Almost killed her, the 2nd one broke, and now the 3rd is/has been working for a while now.

These things do nothing for BT pain, you have no control over them, so she gets a shot of M straight to her spine, + fent pops, and about every IR pill there is.

I wouldn't worry to much about pills going bye bye, it's when someone starts ripping teeth out of the old people then it's gotten bad.

There is another big phram working of smokable pain relief, instead of the 15 min. for relief they say, 5 min at tops, of course we ALL know where they got this idea.

Soon we won't have to crush up the avin. or the OC's, it's already to go. :D

[Cybershark]

Here is the article on the smokable pain killers! Man I would love that in an oxy or morphine vapor form. ;)




http://today.reuters.com/news/articl...src=rss&rpc=22 (http://today.reuters.com/news/articlenews.aspx?type=topNews&storyid=2007-01-31T093316Z_01_N23263374_RTRUKOC_0_US-ALEXZA-SMOKABLE.xml&src=rss&rpc=22)





By Toni Clarke
BOSTON (Reuters) - All self-respecting painkillers these days offer "fast-acting relief," a promise we accept to mean anywhere from 15 minutes to more than an hour.
For Alexza Pharmaceuticals Inc., which is developing drugs for migraine, pain, panic and agitation, "fast" has to mean "within seconds." The Palo Alto, California-based company is developing drugs that can be "smoked," and, like nicotine in cigarettes, pass through the lungs and into the bloodstream almost instantly.

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Investors like the idea.
Alexza's shares have risen nearly 60 percent over the past five months, dramatically outperforming the Nasdaq Biotechnology Index, which rose 15 percent over the same period.
"What makes this an exciting story is how broadly applicable the technology could prove to be," said Charles Duncan, an analyst at JMP Securities, which helped take the company public for $8 a share a year ago. Alexza was formed by biotechnology entrepreneur Alejandro Zaffaroni, who also founded nicotine-patch developer Alza. His latest venture is not the only company that is developing inhaled therapies: Nektar Therapeutics and Alkermes Inc. develop powdered insulin


But Alexza's idea of heating up a drug to create a vapor, or smoke, is unique.
The company's lead product is a vaporized version of an old drug called prochlorperazine, which Alexza is developing for migraine headaches but is currently used in liquid, oral or suppository form to treat severe nausea.
While it is sometimes given intravenously in hospitals to treat patients with acute migraines, the drug is inconvenient to deliver. HIP FLASK INHALERS

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Alexza is hoping to provide similar results but in such a way that patients can carry the delivery device -- an inhaler that looks like a miniature hip flask -- in a pocketbook or the glove compartment of a car.
The device contains a battery-powered package that heats a thin coating of drug to create a vapor that can be sucked into the lungs.
"It's a useful mode of delivery, though its desirability and frequency of prescription will depend on the disorder," said Dr. Jeffrey Lieberman, chairman of psychiatry at Columbia University. The company plans to release initial results of a mid-stage clinical trial of its migraine drug by the end of March. If all goes according to plan, Alexza could file a marketing application with U.S. regulators in 2010


The company is also testing inhalable drugs for pain and anxiety, and for agitation in schizophrenia patients.
While Lieberman doubts there would be much demand for an inhaled product for agitated schizophrenia patients, who would be unlikely to cooperate in taking it, he said there could be benefit for patients with migraine, panic and pain.
"People with panic disorder want immediate relief and would be very cooperative," Lieberman said. "They know that if they take a pill it can take up to an hour to work. This would be a non-stigmatizing way to deal with the situation." Thomas King, Alexza's chief executive, said the company expects to announce a partnership with either a major drugmaker or specialty pharmaceuticals or device company to help develop at least one drug during the second half of this year.

[alowishus]

I had a dream about this shit, woke up so pissed off, because I knew when I looked in the "pill jar" there aint gonna be no inhaler full of OC waiting for me.

[I-Nod]

Dental Implant Administers Drugs

http://blog.wired.com/gadgets/images/6778_2020783011.jpg (http://blog.wired.com/photos/uncategorized/6778_2020783011.jpg)

Researchers are developing a dental implant that administers prescription drugs in small doses over continuous periods. Dubbed "Intellidrug," the implant would be placed inside a pair of prosthetic molars and would release dosages to be absorbed into the mouth's mucous membranes. Ideal for chronically ill patients with large prescription regimens as well as those with mental impairment, the Intellidrug would allow the patient to maintain consistent levels of the drug in the bloodstream. The prototype will be displayed on Feb. 27 at the MedTec trade fair in Stuttgart and will undergo clinical testing later this year.

http://www.gizmag.com/go/6778/
Ingenius... using the mouths membrane to absorb it too, nice.

I could just see people looking like those rappers w/ a grill full of these dental implants. It's a shame we only have 28 teeth :D