Ecstasy, the new prescription drug?

[shadowbox]

This year, the drug MDMA, otherwise known as ecstasy, could take a step toward medical respectability. Researchers in South Carolina have begun experimenting with MDMA for patients with post-traumatic stress disorder (http://www.maps.org/research/mdma/ptsd_study/protocol/protocol051606.pdf).

This is from an interesting article in today's edition of www.slate.com (http://www.slate.com)

Here's a link to the full story: http://www.slate.com/id/2158144/?nav=tap3

[OxyContinuously]

Yeah i heard about that. With any luck it will be re-legalized for use in a medical setting. It has been shown to be very useful in PTSD and other related disorders. Everything from grief and loss to major depression. let's see how that turns out.


oxy

[tptptp]

Yeah i heard about that. With any luck it will be re-legalized for use in a medical setting. It has been shown to be very useful in PTSD and other related disorders. Everything from grief and loss to major depression. let's see how that turns out.


oxy

Doesnt E cause like permanent problems after a bit of consistnet use, like feeling out of touch with reality? Is this not the case with lower therapuetical doses or what?

E is not something I would ever fuck with on a regular basis, of all things I'm surprised they are considering it.

[HistoryofMadness]

hey if you'll believe something you read offa slate i got some beachfront property out here in the desert I swear to god and i'll sell it to ya CHEAP!

always independantly verify all that fucker's bullshit. that site's a joke and how anyone could call it 'news' is beyond me.


p.s. look for the government to pull funding on any research mdma-related if anything good comes from it

[nick]

Some studies suggest long term heavy e use can cause Parkinsons.Then again some studies suggest global warming is nothing to do with burning fossil fuels.
The problem with any reseach tends to be that it's at the mercy of the person/people carrying it out's subjective ideas on the topic.Nevermind having to worry about who funded it

Oh and some doc is working with LSD somewhere in the UK.As well as I believe someone in Canada.

[OxyContinuously]

the jury is out on whether pure MDMA is a neurotoxin or not. Yeah, Nick I heard that too. A lot of times, mdma is confused w street e which can have anything at all in it. Don't get me wrong: I am not saying that taking mdma all the time is necessarily good for you, but it has been shown to alleviate certain symptoms. Wait and see, I guess?


later



oxy

[nick]

Oxy bro,I'm with you.I think the potential benefits outweigh the percieved risks and on a personal note I love E.The problem is finding good E nowdays.

[HistoryofMadness]

the jury is out on whether pure MDMA is a neurotoxin or not. Yeah, Nick I heard that too. A lot of times, mdma is confused w street e which can have anything at all in it. Don't get me wrong: I am not saying that taking mdma all the time is necessarily good for you, but it has been shown to alleviate certain symptoms. Wait and see, I guess?


later



oxy

again euphoria is by definition a cure for depression (which is PTSD's most debilitating effect, right?) but its a short-term solution. maybe a short cycle, with therapy?

it may or may not be a neurotoxin (there's not enough research now) but it will do what opiates do, which is drain your brain of the ability / drive to produce dopamine/endorphins and there's ALWAYS rebound depression with these sorts of drugs.

i don't see how that could be beneficial? anyone ever had a bad time coming down from ex? its pretty fucking depressing.

[Seedy]

^^
seratonin

[moviebuff927]

Hell, ya'll know more about my state than I do...

[moviebuff927]

^^
seratonin

That's right, seedy. It affects seratonin moreso than dopamine or GABA...but no doubt dopamine release has a lot to do with the euphoria of the drug, but seratonin is the neurotransmitter that is responsible for most of MDMA's effects.

Seeing how this is supposedly taking place in my state, I wouldn't want to be the guinea pig for the testing of this drug. Hell, I'll go to any new opiate they want to test out and sign a waiver for my life. But not for MDMA. Opiates and cannabinoids both have receptors in the brain...MDMA and other drugs don't. I don't know if it's neurotoxic or not, but I don't want to be the one to find out (because they just did a test on my brain after they had been giving it to me for testing for 2 years and discover my brain has shrunk to the size of a walnut and my spinal fluid is unbalanced so I'm in and out of paralysis).

I'm sure it feels good, but I'll never know. I tried to buy it one time when I was younger...thank God I got a bunk pill. Not happy that I lost money, but I got the bitch back that sold it to me.

When you drain all your seratonin from the administration of that drug, I believe that can cause CHRONIC depression, where you never fully recover. I've seen E-heads that look like zombies, walking through life not knowing where they're going or where they've been. Sad.

[HistoryofMadness]

^^
seratonin

thanks i was hoping i'd hit the word or someone would help...

[nick]

It's all the e you've done bro.

[HistoryofMadness]

It's all the e you've done bro.

ha prolly right

[Seedy]

Yeah I guess it makes sense that mdma would release dopamine as well being a chemical related to amphetamines.

I think (but might be wrong) that if used wisely e is pretty harmless - that is no more than, say monthly. Sure if it's used on a regular basis it will cause seratonin depletion & cause depression but from personal experience it's only short term. When I was using it weekly (for close to a year straight) the depression kind of "built up", and the drug just stops working (not enough seratonin to dump, I guess), but after stopping using for a couple of months I was back to normal.

Millions of people in the UK use it every weekend so I guess we'll soon be finding out the consequences of that!

[OxyContinuously]

exactly, seedy, it's like anything else. just be informed, and be responsible.

I mean i like having a couple beers every now and then (not a big drinker) but that doesn't mean that I would drink every day, or drink 15 beers every day, you know?

good point

[Chipper]

I enjoy E but I have found that if taken regularly, it causes a type of depression that we call "Eccy Tuesday"; it's best taken at 3(+) weekly intervals, in my opinion.

One more thing, don't take it when in w/d (you will feel worse).

Oh how I wish it were legal ...

[OxyContinuously]

I enjoy E but I have found that if taken regularly, it causes a type of depression that we call "Eccy Tuesday"; it's best taken at 3(+) weekly intervals, in my opinion.

One more thing, don't take it when in w/d (you will feel worse).

Oh how I wish it were legal ...


you got that right. pure mdma (not this molly garbage or other shit that is being passed off as real E) causes a massive release of serotonin, and your brain literally needs time to recover and recuperate it's serotonin after a night of E!! And like you said, the depression usually hits home a couple days after you partied. It is really ridiculous, though, and oh my; I can't imagine how bad you would feel after it wore off if you were dopesick as well!!

oxy

[alowishus]

The problem is finding good E nowdays.

heard of some crystal in tyne and wear, very nice indeed. :D

[nick]

Yeah,but Im not brave enough to hang out in Newcastle and by the way Seedy there are supposed to be 1 million doses dropped in the UK every weekend,but most of them aren't MDMA most are god knows what.
I've only seen real MDMA once in 15 odd years and I look hard.

[alowishus]

Newcastle

Ah... now that's good in a glass.

Well here, for the states that is, I miss Canada some times, 12% Labatts'...:drunk:

I thought you guys were swimmimg w/ pure stuff, w/ all the shady eastern europe blokes you got en all.

[SuperJunky]

I've taken E maybe 10 times, never more than twice in a week and never more than 1 week every three months. I've never found it to cause an after depression. It actually motivated me to get off dope for a short stint once. Any one ever combine E w/ opiates? I've done this twice, once when I was snorting and once after I started shooting. I swear that is the best possible type of speedball. Right after you do the dope (even when I snorted it) it feels like your heart is going to be ripped in half and explode, but then its the absolute best high in the world. Its not something I really seek out though, I wait for it to come to me. It always seems to when I need that type of experience the most. I never used it in a club setting though, mostly just a chill setting w/ friends. I always stayed hydrated, lotsa gatorade. Nicotine seems to potentiate it like all hell, when ever I have E I always get camel wides. I would assume because of this it acts on the dopamine system, and while I believe it probably works on the endorphin system as well I would think if this is were the majority of the euphoric affects come from it would be cross tolerant w/ opiates to some degree.

I think E if used sparingly is harmless. I know MAPS is always working towards funding MDMA, canabis etc studys. I remember geting there news letter a while back and the headline read something along the lines of MDMA study aproved by FDA. I believe its use in treating post traumatic stress disorder is to make the person more open for counselling sessions. It was used by a lot of psychologists psychiatrists in a counseling setting very sucsesful before it was scheduled. If memory serves, and please some one correct me If I'm wrong, but there was a huge trial were thousands of witnesses were called on MDMA's behalf and the supreme court ruled that MDMA be placed in schedule 3 but the DEA claimed that it was not the courts decision to make, mdma had no medical use, and placed it in schedule 1. I believe I read that in a book called "The pursuit Of Ecstacy." Any one?

[Seedy]

Yeah,but Im not brave enough to hang out in Newcastle and by the way Seedy there are supposed to be 1 million doses dropped in the UK every weekend,but most of them aren't MDMA most are god knows what.
I've only seen real MDMA once in 15 odd years and I look hard.


Good point. I forget about all the shit pills. Allthough we pay rediculus amounts here for pills it seems when people actually go the effort of bringing them into NZ they make sure they're good ones. Or pure mdma. I haven't had a shit pill in years.

I'd guess that 1 million doses dropped per weekend in the UK would be a fairly conservative estimate. You guys know how to party!

[jacky]

the military has been using x for a few years now for a research project on PTSD. you got to be a returning veteran though.
I need to look up more of what I can on this type of thing.

think augmentary cognition program.
or
aug/cog
for short.

it is the militarys psychoactives research program. to build a better soldier.

saw some speaker talking about it during the paranoia panel discussion.

[Nile_dancer]

I've tried E a few times, and I recovered okay. Maybe I was a bit brain-dead the next day or so (e-tarded), but the high was definateley worth it.

As far as nuerotoxicity is concerned, I have read that the major study claiming it to be a nuerotoxin has been withdrawn as a bad study. Apparently, the circumstances were pretty suspicious too; it looks like the study was intentionally misleading. Not that it isn't a nuerotoxin, it's just the major study saying it is, is bunk.

I've also been hearing positive things about e as well: that it does wonders for parkinsons patients, and may actually cause the brain to grow dopamine receptors (which you lose as you age).

Here's a thought that I've been thinking that's related to E: We know (studies have shown! ) that really bad traumatic events can cause disease. Well... what then, can a really good event cause? Health?

[AWOL]

I read about this a long time ago, they've been testing it in psychiatric cases for victims so that they will open up. As far as I've heard it is not getting prescribed as like a day to day thing, it's being used like, twice with victims of some abuse to get them to open up.

They already do this with other medications btw.

[Dolophine]

I can attest that ecstacy causes long term brain damage as I suffer from it. I'm totally serious, I don't really want to talk about the problems I have but ecstacy has caused me a great deal of pain and stolen my life from me. Don't do it if you want to live. It will turn you into a total e-tard and mess up your perception of time, reality and all sorts of other things. I can't even judge when to cross the street because I can't guage how fast cars are going anymore. And at night the taillights on cars are blinding and streak and it'sbeen 5 years since I did ecstacy. All it takes is a couple overdoses. That's what did it to me. 15 pills or so and boom, instant brain damage. I have constant memory problems too I can't even remember what I did on any given day. If you ask me what I did today i couldn't tell you. I know I watched movies but I don't remember which ones or how many.

Stay away from Ecstacy you'll thank me later. And if you get whacked out on E and OD on it you'll be saying fuckk I should've listened to Dolophine cuz i'm a fucking brain damaged retard now and I can't go outside or do anything anymore and light is 1000 times brighter than it was before ecstacy and sometimes I blank out, and all sorts of shit happens! STAY AWAY FROM ECSTACY AND METHAMPHETAMINE

[Seedy]

^^
I'll stay away from meth but I gotta say, taking 15 e's at once isn't too bright. You never know what's in them.; It was probably one of the additives (bzp maybe) that fucked you up. 15 x a little bit of something nasty per pill would probably damage your brain. Actually, so would 15 x 100mg of mdma. Why the fuck would you take that much?

Sorry about the brain damage though that sucks.

[dRuGsSsS]

I can attest that ecstacy causes long term brain damage as I suffer from it. I'm totally serious, I don't really want to talk about the problems I have but ecstacy has caused me a great deal of pain and stolen my life from me. Don't do it if you want to live. It will turn you into a total e-tard and mess up your perception of time, reality and all sorts of other things. I can't even judge when to cross the street because I can't guage how fast cars are going anymore. And at night the taillights on cars are blinding and streak and it'sbeen 5 years since I did ecstacy. All it takes is a couple overdoses. That's what did it to me. 15 pills or so and boom, instant brain damage. I have constant memory problems too I can't even remember what I did on any given day. If you ask me what I did today i couldn't tell you. I know I watched movies but I don't remember which ones or how many.

Stay away from Ecstacy you'll thank me later. And if you get whacked out on E and OD on it you'll be saying fuckk I should've listened to Dolophine cuz i'm a fucking brain damaged retard now and I can't go outside or do anything anymore and light is 1000 times brighter than it was before ecstacy and sometimes I blank out, and all sorts of shit happens! STAY AWAY FROM ECSTACY AND METHAMPHETAMINE


I disagree. Now each person is differnt in there reactions and tollernce to E or for that matter any substances. But I have personally have taken at LEAST 200 pills over a 2 year period and i am completely fine- "15 pills or so and instant brain damage"--bullshit. Now when I was in my E-tard phase was about 2000-2002 ish and the pills or crystlas I was getting where stright from Europe and they pure MDMA or MDA (rarely MDA) this was when E was E not what is going around these days. They were very, very strong and pure pills. At the hieght of my binge I used E daily for about a 2 month period taking an average of 5 pills daily, and the most I ever took in about a 24 hours priod was 10. I will say that after my month hard core binge that I was very depessed and NEEDED to take a pill as soon as I woke up to "feel normal" then later I would take a couple evry 6 hours to get high, but needed that one ASAP or I would be very low and depressed. The night I took a total or 10 was me pushing the limits way to much, and I ended up with an OD. I dropped at a party and eneded up in the ER, it was very scary, and I almost died, but that is becasue I took way too many. When i got out of the ER a good freind took my pills casue she relized what I was doing, and I knew I would OD agian at the rate I was going..I stopped taking them after that fateful day, and have only took E one more time since then. And that was some MDA crsystals, and some point in my life I will do it again if the time is right, but the key is moderation, moderation! MDMA_MDA is very powerful, eye opening, mood altering, soul changing, substance. It did help me get through some personal issues, and I am bl to express my feelings and open up to others. But again I am as normal as I can be..;) I know many people whom as took as much or more hten i have and they are fine, no brain damage, or long lasting damage casued by the drug. I am not doubting what you said, but again it could be YOUR brain reaction, everyone is differnt. I am not advocating taking hunderds of pills, but as long as you TEST yoyur pills to ensure the are not adulterated and you are getting MDA_MDMA it is a safe substace to use moderattly. I can not stress enough to TEST< TEST< TEST your pills they kits are cheap and you can buy them off the net, NEVER, NEVER swallow a pill without testing it!! These days pills are cut with meth, ketamine, BZP, almost anything or it can be deadly such as PMA.

[Nile_dancer]

How do ya test them? Oh, I see, test kits.