View Full Version : Tramadol and Ketamine
SuperJunky
01-01-2007, 09:47 PM
Any one have any experience mixing these 2? I would think its safe but then again I have a tendancy to think K can do no harm and goes w/ everything, esp when I start using it. This is part of my plan to kick, or atleast kick down. I usually use H, pharms or pods etc. I have some putty to use to.
Sorry this is kinda spacey and incoherant, or so I percieve it. I'll clear shit up when I come down. Just want to get this out there so I can start getting feed back. I dont think there's a ssri K interaction, but I know there is a dxm ssri interaction. DXM, my old love. Cant stand it any more, i love dissasociatives (did I actually spell that right, WTF?) but I find dxm to be a "black" drug while K is at the other end of dissasocie fun, a "white" drug. DXM is a cold icey hand reaching through your body and ripping your soul from your spine aka nervouse system and K is flowers and clouds.
Anyways I'm definatly twisted and need some advice asap. Gonna google k and ssri. Have to go this route in the morning. Is it strange that If they dont go together I might go the K instead of the tram? Tram has saved me from hardcore wd before but K can overpower anything, even dmt so how could wd poke through?
Papa Verine
01-01-2007, 10:02 PM
Any one have any experience mixing these 2? I would think its safe but then again I have a tendancy to think K can do no harm and goes w/ everything, esp when I start using it. This is part of my plan to kick, or atleast kick down. I usually use H, pharms or pods etc. I have some putty to use to.
Sorry this is kinda spacey and incoherant, or so I percieve it. I'll clear shit up when I come down. Just want to get this out there so I can start getting feed back. I dont think there's a ssri K interaction, but I know there is a dxm ssri interaction. DXM, my old love. Cant stand it any more, i love dissasociatives (did I actually spell that right, WTF?) but I find dxm to be a "black" drug while K is at the other end of dissasocie fun, a "white" drug. DXM is a cold icey hand reaching through your body and ripping your soul from your spine aka nervouse system and K is flowers and clouds.
Anyways I'm definatly twisted and need some advice asap. Gonna google k and ssri. Have to go this route in the morning. Is it strange that If they dont go together I might go the K instead of the tram? Tram has saved me from hardcore wd before but K can overpower anything, even dmt so how could wd poke through?
Hey Super Junk, you're comparing 2 different ways to deal with W/D. You can take Tramadol, keep your sanity, feel "not too bad" for a few days... or you can do K and just "not be there" while the rest of you kicks dope. If you consider K to be "flowers and clouds" then go for it. Enjoy your withdrawls...
To me, dissacoicatives are not something I can do for a few days at a time. I have to take a break back here in "Reality" every so often. You might want to try Ibogaine!!!
SuperJunky
01-01-2007, 10:08 PM
I know Im comparing two different methods, I'm so torn on what to do. If only I cold just slam H and K together forever. :) While K is flowers and clouds to me your body will still WD, which is never fun, and If your bodys not happy regaurdless of the mind over matter thing on some level it still affects your mental state, so it probably wont be great but I'm sure it wouldnt be to bad. Im not sure of anything. sigh.... Thanks for putting it like that though, even though I know things doesnt mean that I aware of it all the time.
Papa Verine
01-01-2007, 10:23 PM
I know Im comparing two different methods, I'm so torn on what to do. If only I cold just slam H and K together forever. :) While K is flowers and clouds to me your body will still WD, which is never fun, and If your bodys not happy regaurdless of the mind over matter thing on some level it still affects your mental state, so it probably wont be great but I'm sure it wouldnt be to bad. Im not sure of anything. sigh.... Thanks for putting it like that though, even though I know things doesnt mean that I aware of it all the time.
WD are never fun, that's for sure. But, nowadays, I just try to help in little ways, Tramadol, Benzos, Warm baths... shit like that. It sucks but at least you have your sanity you know??? You can reach over and turn a lamp off without it "breathing" at you.
SuperJunky
01-01-2007, 10:44 PM
K makes things really weird for me but it isnt scary or really insane, just temp screwy. Every things connected but lamps dont breath at me, sometimes they dissapear or fade out.
Any one ever taken K and an SSRI like prozac etc?
SuperJunky
01-01-2007, 11:05 PM
I found this @ http://cat.inist.fr/?aModele=afficheN&cpsidt=13623836
itre du document / Document title
Isobolographic analysis of the analgesic interactions between ketamine and tramadol
Auteur(s) / Author(s)
YONG CHEN (1) ; CHAN Sui Y. (1) ; HO Paul C. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Pharmacy, National University of Singapore, 10 Kent Ridge Crescent, 119260, SINGAPOUR
Résumé / Abstract
Owing to different mechanisms of analgesia, we hypothesized that the combination of ketamine and tramadol could produce synergistic or additive antinociceptive effects. Swiss albino mice were administered intraperitoneally with ketamine, tramadol, a combination of ketamine and tramadol, or saline, and the resulting antinociceptive effects were tested in the mouse tail-flick and formalin tests. The potencies of the two drugs alone or in combination were obtained by fitting data to the Sigmoid E[max] equation. Isobolographic analysis was performed to evaluate the interaction. CNS depression was also monitored. Results showed that tramadol exhibited apparent dose-dependent effects in the tail-flick test, and in phase 1 and phase 2 of the formalin test. Ketamine dose-dependently inhibited the phase 2 responses, but failed to modify the phase 1 and tail-flick responses. Combination of tramadol and ketamine produced significant synergistic interactions only in phase 2 of the formalin test (P < 0.05). The synergistic combinations also displayed less CNS depression than when an equianalgesic dose of ketamine was administered alone. We conclude that in the acute thermal or chemical pain model, ketamine is not effective and the net effect of ketamine and tramadol in combination was simply additive after systemic administration. However, the coadministration produced synergistic antinociception in the chemical-induced persistent pain model.
This was interesting to, but too long to post http://www.anesthesia-analgesia.org/cgi/content/full/97/1/104
Used to do loads and loads of i.v. ketamine. Also have taken lots of tramadol. Had seizures on two different occasions with tramadol Never mixed the two though.
Ketamine for me was weird and strange but not scary too (except the time the refrigerater in my grandma's garage started mumbling to me in refridgerator language, or the time that I was absolutely certain that the sleeping bag on the bed I was lying in was going to swallow me up and slowly digest me). mheh heh he....
Go for it!
Hey I been layin low for a spell. I'll be back round for a few days I guess. Everythin's going fine for the moment. The old lady let me move back in and I'm on good good good behavior. 's nice. I had to switch to suboxone :mad: to placate her about my buprenorphine maintenance therapy though. She knew I was slamming the subutex.
Papa Verine
01-01-2007, 11:48 PM
Used to do loads and loads of i.v. ketamine. Also have taken lots of tramadol. Had seizures on two different occasions with tramadol Never mixed the two though.
Ketamine for me was weird and strange but not scary too (except the time the refrigerater in my grandma's garage started mumbling to me in refridgerator language, or the time that I was absolutely certain that the sleeping bag on the bed I was lying in was going to swallow me up and slowly digest me). mheh heh he....
Go for it!
Hey I been layin low for a spell. I'll be back round for a few days I guess. Everythin's going fine for the moment. The old lady let me move back in and I'm on good good good behavior. 's nice. I had to switch to suboxone :mad: to placate her about my buprenorphine maintenance therapy though. She knew I was slamming the subutex.
I wish you the best Zoop!!! Old Lady's always drove me crazy but I hope you and yours are doing well!!!!!
SuperJunky
01-01-2007, 11:50 PM
Hey havnt seen you around in a while zoop. Glad things are going ok, sucks your on that awful suboxone shite. Even when you take as prescribed it isnt the same a subutex as prescribed is it?
I guess tram and K are ok together, dont know what it will be like at recreational doses. I'll let every one know either tomarrow or the next day.
satori
01-02-2007, 12:31 AM
My first thought that came to mind when reading title was "TERRIBLE FUCKING IDEA"
SuperJunky
01-02-2007, 08:51 AM
alright boys and girls of earth this how thigs are goin, woke up, feel like shit, but then again who likes waking up? cooked cottons, nothing. scraped bags, nothing. Ate 5 grams of putty and 2 tagment, gonna eat more putty later. Did a bump of k, then another. I feel fine as long as im not sneezing. I'll see what the putty has done when I come down, if nothing its tram and another bump.
SuperJunky
01-03-2007, 06:56 AM
Well it didnt do a damned thing, the putty that is, so I did about 25-35mg K IN every 45-hour, I cant sleep, even after taking 20mg valium and a 100 beadryl, which is a lot for me. Siting here tracking fedex package. Hurry Up God Damnit. Anyways, I can barely sit still, time for some more k.
jacky
01-03-2007, 12:30 PM
yeah, K and tramadol are OK, I also have combined dxm, K, and salvia divinorum and DPT with tramadol and codeine.
I am not a garbage head really. that particular night was an experiment to try and discern different effects of these nmda antagonsists/kappa agonists. salvinorin a, ketamine, and dxm have their own signatures for sure. used together in low doses was a good experience, controlled, meditative, and serene.
salvinorin a can sure rip you in half though as getting a prime dose can be hard.
I found that on DXM, small amounts of IV ketamine do far more than when just using K. I would take 10-20 milligrams and experience alot more than I would have expected.
IV DPT is NOT for me though, even when on dxm that seems to mute the effects a bit.
I used K once when detoxing off of heroin. I had never done it before, and did a good OBE dose. it really helped me for at least a week fend off cravings. I was too blown away by new possibilities to consider going back too soon to dope. I was homeless at the time, and the K really centered me for awhile. I used it a week later when I felt like I was going to relapse as everyone around me was doing dope.
ketamine helped me wake up from my atheistic depression, and get back to studying buddhism and comparative religion.
slugbone
01-03-2007, 12:40 PM
i didn't know you dug buddhism jacky, that makes more than a few of us on this site (me included) that study buddhist philosophy. it must be something about opiate addicts that are drawn to it. at least that is my half assed theory.
Chipper
01-06-2007, 05:10 AM
Have mixed about 100 mg K with 20 mg Methadone. The Ketamine did not come on as strong; I see no benefit in mixing the two.
SuperJunky
01-15-2007, 11:14 AM
I finally got pushed up against the wall, took 200 mg tram and did some k, aprox 30 mg, seemed to mute the k. took 100 more mg tram, did 50 more mg k, cant say i even notice wd. reality, he
OxyContinuously
01-15-2007, 11:32 AM
In my experience i have found that an intramuscular injection (26 gauge--that's one hell of a spike) of DPT (dipropyltryptamine) given in the shoulder eases WD and it also puts you at peace *with* the WD so even after you come down, you deal with it. Plus, DPT is a fucking mindblowing psychedelic, and trust me, I've done 'em all!!
If anyone was wondering, 45mgs is quite enough for the IM route
Oxy
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