Tylenol and liver damage

[satori]

Does anybody know how long it takes to start to cuase liver damage? When using tylenol i mean. I have started to read that just daily use of under 4 grams can start to cause damage.

[moviebuff927]

It will take a while, but it's still not worth taking it for a long period. Look into NAC, a supplement you can only get at GNC. It's given in hospitals for people with overdoses of Tylenol and is currently the only treatment for tylenol poisoning. But you have to take it within a short amount of time. I used to take it before and an hour after taking anything more than 2 grams of tylenol at a time.

It is an anecdote, but it's still wise to not take too much tylenol if you don't have to. But if you take 3+ grams of tylenol a day, you could start to see problems in as little as 6 months.

[pinion]

Pretty much anything over 1.5 - 2g daily is something to be concerned about. A lot depends on your age, alcohol intake, current state of health (got Hep C? You sure? I've heard figures as high as %95 of IV users do..)

CWE is SO easy once you get it down, there's little excuse not to do it. I was living in my truck and doing it daily in Canada last year, of course the snow helps cool it down but it really is very easy. And not only that, liver disease is a very, very ugly way to die..

[red26]

I wonder/worry about this as well. Too much of anything is bad, but theres cirtain things to keep your eye on like tylenol.

[satori]

Ive never used a needle before and was tested for that and many other things 6 months ago (all negative). I dont drink alcohol and im 21. I have only bought small amounts of OTC tylenol codeine and when i did i did do OTC. I have never taken more then 1.5 grams at a time and when i did i didnt take more tylenol that day.

I have always gotten vicodin and cough syrups so i never did extract but i know there are a lot of 24 hour periods hwere i got up to 4grams. It hasnt been very steady. I will get a perscription and take it but i dont remember a time where i went over 4 grams in a 24 hour period. Most of the OTC opiates i have gotten have been ibeuprofen + codeine. But i still have taken tyleonol quiet frequently (APAP).

Should i go get a blood test?

[satori]

I have a tendancy to obsess over things really really bad. Is this one of those things i should really be worying about or would be there major signs or symptoms if something bad was going on? Im going to avoid tylenol whenever possible now and not use the tylenol codeine i have and just stil to codeisan.

[pinion]

I think you're probably alright. But who am I? Some wannabe on an Internet forum? I suggest you do your own research (google.)

I think it's the FDA that says <4G/day is safe. Fuck the FDA, they lie like snakes. The truth is, if your main source of opiates is OTC codeine/hydro, then you have a lot of APAP in front of you ('cause you're probably not going to quit) and I recommend you learn how to filter it out. It (APAP and NSAIDS) are not very water soluble, while codeine and friends are so it's probably not hard to get it out of the syrup solution. I don't know this for sure, maybe google or someone here can help you with that. Otherwise , if you're dead set on the opiate thing then you might want to look into other alternatives because in the long run, the APAP will fuck you up.

Liver disease is a nasty, nasty way to die and it has a real tendency to sneak up on people.. I.E. fine one day, yellow the next and then dead in a few months..

[shadowbox]

pinion is right - CWE is way easy once you've got your method down. If i'm taking hydro i take a compound of 15mg hydro/200mg APAP and even those I'll do a CWE on. same if i have to take Norco which have 325mg of APAP. When you do a CWE on about 5 of these you get a scary amount of APAP sludge in your filter. I look at that and think, Glad that's not goin thru my liver....

[Papa Verine]

I have a tendancy to obsess over things really really bad. Is this one of those things i should really be worying about or would be there major signs or symptoms if something bad was going on? Im going to avoid tylenol whenever possible now and not use the tylenol codeine i have and just stil to codeisan.

DON'T WORRY ABOUT IT!!!!

Your internal organs are fine. I've put my body through MUCH worse. You're young and healthy. Your liver is fine. You've been tested for diseases and you don't have any. I've done things to my body that you wouldn't believe if I told you. I'm still here and I'm relatively healthy.

[nick]

DON'T WORRY ABOUT IT!!!!

Your internal organs are fine. I've put my body through MUCH worse. You're young and healthy. Your liver is fine. You've been tested for diseases and you don't have any. I've done things to my body that you wouldn't believe if I told you. I'm still here and I'm relatively healthy.
Papas quite right.I wouldn't worry about apap when there's so much shit to really worry about,but if you're abusing otc dope with a lot of apap in it go for the CWE as that nice Pinion suggests.

[satori]

I dont use OTC opiates except for what i have just bought recently and i always did a CWE on them. I would get vicodin or tylenol 3 before thats what im worried bout i guess. I dont ever remember taking more then 6 a day or at most 8 but even with that i never had more then 30 at a time.

[satori]

DON'T WORRY ABOUT IT!!!!

Your internal organs are fine. I've put my body through MUCH worse. You're young and healthy. Your liver is fine. You've been tested for diseases and you don't have any. I've done things to my body that you wouldn't believe if I told you. I'm still here and I'm relatively healthy.


Once i find out there is a possibility of something being wrong like (liver disease) i cant stop osessing about it. I had known tylenol was dangerous but the bottle said do not exceed 8 extra strength in a 24 hour period.

[Buckshot]

I've worried about it also. From avoidable stuff, like neglecting to do an extraction and just eating 50 T1s which is 15 grams of acetaminophin.

The LD 50 is still debated but the upper range in a single "acute" dose of 7.5 grams to 10 grams. When I ate 15 grams I checked in to the emergency room. (Free in Canada) they put me on the NAC via IV drip for 24hrs.

However, if you decide to tuff it out, know this. Acetaminophen poison shows no symptoms until your skin or eyes turn yellow. And that wont happen until 48-72hrs after you ingested the acute dose. So you worry for 3 days....And dont have any liquer during those 3 days.

If you ate more than 12.5 grams and you are less than 200lbs or a heavy drinker, do not take this chance.

You can sneak by one or two times, then your liver has fat deposits on it for life....Or until you have a liver transfer...Hmm, that hitch hiker looks healthy.

Acetaminophin poisoning is the single largest cause of emergency visits for a heptic liver.

Just google acetaminophen toxicity levels....ohh and there are two groups for this. Suicide attempts and people seeking pain relief "accidently" ingesting too much. The latter group has a much higher mortality rate.

[Papa Verine]

Once i find out there is a possibility of something being wrong like (liver disease) i cant stop osessing about it. I had known tylenol was dangerous but the bottle said do not exceed 8 extra strength in a 24 hour period.

You should realize that the drug company that makes Tylenol has to be extremely cautious about what they print on the bottle. They can be held liable for any harm done from their product and people are real quick to sue them over anything!

Don't do this but when younger I took over 8,000mg of acetomenophen in a 24 hour period numerous times. My liver made it. I have a freind who consumes this amount on a regular basis in the form of Vicodin. I keep telling her to STOP and I've taught her how to do a CWE but she won't fucking listen to me. She's still fine too with no liver damage YET.

[satori]

If i had liver damage it would be fairly obvious right? I have been reading and understand this is a difference between dysfunction and desease i seriously doubt i have desease and even doubt dysfunction. I kep reading about people taking 10 grams a day (addicted to hydrocodone) and they still have there livers working like normal. I dont ever remember a time i went over the 4gram a day max (ever). THis one has seriously gotten to me though im staying away from tylenol period. I will CWE everything except maybe norco.

[satori]

I've worried about it also. From avoidable stuff, like neglecting to do an extraction and just eating 50 T1s which is 15 grams of acetaminophin.

The LD 50 is still debated but the upper range in a single "acute" dose of 7.5 grams to 10 grams. When I ate 15 grams I checked in to the emergency room. (Free in Canada) they put me on the NAC via IV drip for 24hrs.

However, if you decide to tuff it out, know this. Acetaminophen poison shows no symptoms until your skin or eyes turn yellow. And that wont happen until 48-72hrs after you ingested the acute dose. So you worry for 3 days....And dont have any liquer during those 3 days.

If you ate more than 12.5 grams and you are less than 200lbs or a heavy drinker, do not take this chance.

You can sneak by one or two times, then your liver has fat deposits on it for life....Or until you have a liver transfer...Hmm, that hitch hiker looks healthy.

Acetaminophin poisoning is the single largest cause of emergency visits for a heptic liver.

Just google acetaminophen toxicity levels....ohh and there are two groups for this. Suicide attempts and people seeking pain relief "accidently" ingesting too much. The latter group has a much higher mortality rate.


I havent taken a large dose of tylenol in months. Even then it was 1.5 grams (2, 7.5mg/7500 hydrocodone). Im worried about the fact i have taken it so often for periods (everyday for a month) etc. It would have taken me 3-4 days to take 12 grams. I weigh 220 and im 6'3 1/2.

[nick]

Satori bro,if your liver doesn't hurt and it's been months your OK.If you're really worried go see a doc to put your mind at rest.In fact if you haven't got hep you're doing better than most of us.Although I doubt that makes you feel any better.
Worry about violent crime,the cops or global warming they're more likely to fuck you up.

[satori]

Satori bro,if your liver doesn't hurt and it's been months your OK.If you're really worried go see a doc to put your mind at rest.In fact if you haven't got hep you're doing better than most of us.Although I doubt that makes you feel any better.
Worry about violent crime,the cops or global warming they're more likely to fuck you up.


Your right. Sometimes i think i feel something wrong with my liver. But i also feel there is something wrong with my heart, lungs, eyes, and adnoids so i dont really know what to trust. This one deff. took me by suprise, had a really hard time sleeping last night or doing anything today.

[satori]

Wanted to add that i have had maybe 6 beers in the past 3 years. Not sure if that is significant or not but i thought i would add it.

[AWOL]

I'd say you should worry about worrying bro. I know you've got OCD, but I have friends with OCD and they can / do get better at it (I've been to the psych ward a few times, made friends). They're not cured, but they're doing much better.

Worrying about all the small stuff is more detrimental to your health than anything, and if I’m counting right this is the third time you’ve thought your liver was damaged.

And I’m not trying to come off as an ass at all bro not at all. I understand how hard OCD is to deal with at least a little from the people I know. But, from what they’ve told me they started to focus on worrying about worrying instead of worrying about this or that and they did improve over time. I’ve known one of them for over a year and half and they’re doing much much better these days. It’s not an overnight thing, but over time they improved a lot. But just remember if you’re worrying about all this stuff so much that it’s disrupting your life, in reality that’s more detrimental to you that what you’re worried about. Loosing sleep, the constant non-stop stress, all of those things are detrimental to your health and life and the difference is that those are something that you can change where-as what you’re worrying about you can not change. Worry about worrying. In all sincerity my best of wishes to you. Happy holiday.

[SpecialGuy69]

Wanted to add that i have had maybe 6 beers in the past 3 years. Not sure if that is significant or not but i thought i would add it.

HOOOOLY SHIT your fucked. j/k. 2 beers a year isn't even worth mentioning. You're fine satori. I'd be more worried about the impending economic collapse due to west nile virus and avian influenza.

[Papa Verine]

I'd say you should worry about worrying bro. I know you've got OCD, but I have friends with OCD and they can / do get better at it (I've been to the psych ward a few times, made friends). They're not cured, but they're doing much better.

Worrying about all the small stuff is more detrimental to your health than anything, and if I’m counting right this is the third time you’ve thought your liver was damaged.

And I’m not trying to come off as an ass at all bro not at all. I understand how hard OCD is to deal with at least a little from the people I know. But, from what they’ve told me they started to focus on worrying about worrying instead of worrying about this or that and they did improve over time. I’ve known one of them for over a year and half and they’re doing much much better these days. It’s not an overnight thing, but over time they improved a lot. But just remember if you’re worrying about all this stuff so much that it’s disrupting your life, in reality that’s more detrimental to you that what you’re worried about. Loosing sleep, the constant non-stop stress, all of those things are detrimental to your health and life and the difference is that those are something that you can change where-as what you’re worrying about you can not change. Worry about worrying. In all sincerity my best of wishes to you. Happy holiday.

I couldn't have said it better. (6 beers in 3 years???)

[satori]

I'd say you should worry about worrying bro. I know you've got OCD, but I have friends with OCD and they can / do get better at it (I've been to the psych ward a few times, made friends). They're not cured, but they're doing much better.

Worrying about all the small stuff is more detrimental to your health than anything, and if I’m counting right this is the third time you’ve thought your liver was damaged.

And I’m not trying to come off as an ass at all bro not at all. I understand how hard OCD is to deal with at least a little from the people I know. But, from what they’ve told me they started to focus on worrying about worrying instead of worrying about this or that and they did improve over time. I’ve known one of them for over a year and half and they’re doing much much better these days. It’s not an overnight thing, but over time they improved a lot. But just remember if you’re worrying about all this stuff so much that it’s disrupting your life, in reality that’s more detrimental to you that what you’re worried about. Loosing sleep, the constant non-stop stress, all of those things are detrimental to your health and life and the difference is that those are something that you can change where-as what you’re worrying about you can not change. Worry about worrying. In all sincerity my best of wishes to you. Happy holiday.

No offense taken (you didnt come off as an ass) i agree with you completely. I normaly have more control but some things have happend over the past month that have really knockd me off my feet. I am working on it though. Atleast i am trying to. Its actualy why i take opiates. When it take them much of my compulsive acts stop (twisting hair in specific order, touching teeth with toung in semetrical shapes, walking "even", plus a thousand rituals i wont even start to list.

However I dont think i ever thought it was damaged before i was worried that enough tylenol might have gotten through a filter to cause damage (cant find the right smiley face to insert here so imagine a halo over a smiley face). You are completely right though. I usualy have more control over it but it has gotten progressively worse overthe past 6 months and especialy over the past two. My sleep schedual has gotten really messed up. Sleep at 6(morning) wake up at 2. Sorry for posting so much after i had read that about tylenol use over long periods of time and liver damage....... Yea.

[satori]

HOOOOLY SHIT your fucked. j/k. 2 beers a year isn't even worth mentioning. You're fine satori. I'd be more worried about the impending economic collapse due to west nile virus and avian influenza.


No i was saying 6 in that time because i had read that alcohol use + tylenol makes it muchmore likely. I was saying i havent been drinking so that wouldnt be a factor making it worse. I was going to say i hadnt drank at all but i had to be exact.

[red26]

No i was saying 6 in that time because i had read that alcohol use + tylenol makes it muchmore likely. I was saying i havent been drinking so that wouldnt be a factor making it worse. I was going to say i hadnt drank at all but i had to be exact.
I know that others have said it, but really no need to worry Satori. Honestly. I take apap on a regular basis and drink some booze around once a week, maybe twice. Like you I was concerned about this due to the fact that I have to take a truck-load of asprin and apap daily, but I'm currently having no re-percussions from it. At your rate it'd probly take at least 10 years to do any dammage.

[satori]

I have a bunch of red spots (age spots) which was what sent me into a frenzy trying to find out what was wrong. The thing is i have had them for years and i get a couple dozen every year but i had started getting them long before i was taking apap. I had seen an indocrinologist(sp) for a different physical problem and he had said it wasnt anything to worry about plus all my blood work came back ok (about 8 months ago). Still reading about the age spots as a symptom ... AHHH

[red26]

I have a bunch of red spots (age spots) which was what sent me into a frenzy trying to find out what was wrong. The thing is i have had them for years and i get a couple dozen every year but i had started getting them long before i was taking apap. I had seen an indocrinologist(sp) for a different physical problem and he had said it wasnt anything to worry about plus all my blood work came back ok (about 8 months ago). Still reading about the age spots as a symptom ... AHHH
I know whatchya mean about the spots. I have a patch on my back. One day it started itchin me sumpthin awful so, when I scratched it a huge slab of skin pulled off into my hand. If I het tan there its always white. Also I got spots all over me and I know its cancer but I dont give a fuck. I have a few wierd places that look different and when you press on them they sink down to the bone. AND! I got this spot on my chest around one of my tats thats always itchin, and when I scratch it I bleed thu my pores.

But really!!! Dont worry bout the APAP.

[satori]

I will try not to worry. I always end up worrying about something (working on that). Now that i mentioned my little red dots im thinking about them. Those damned multiplying red spots. Freckles almost. Blood freckles. That plus my liver damage and tumors i must have are really getting to me. The damned tumors! On a possitive note i have adderall so i actualy have energy during the day. Thats always good.

Adderall, codeisan, xananx, clonopin, valium, fioricet, Poppy extract = good upcoming month