Tramadol & alcohol

[tptptp]

one of my friends who has no tolerance got high a couple times off of about 190mg of tramadol WITH acetiminophen in it - US manufactured. like a month later without dosing since he took 200mg tramadol w/OUT acetiminophen manufactured in thailand and needed to pop another 100mg an hour later because it wasnt strong enough. This time he had been drinking quite a bit though. This thai distributor is praised by many as having good stuff so....

1)Did the tylenol in some way contribute?
2) Did the alcohol actually LESSEN the high?
3) Is the thai's tramadol crap? he got it from clickDS for those who know what that stands for...

swim tried some of it, and it works, but he cant gauge that weak shit anymore

thx

[flipside]

Hard to say TP, but I would imagine the ETOH probably dulled any effect he would have felt from the Tramadol. Just a guess.

[tptptp]

Thanks Flip thats what I was leaning torwards as the answer I *think*, what exactly does etoh stand for though? Im assuming your referring to the alcohol....If so thats my guess, but not 100% sure

[flipside]

Yep sorry ETOH is alcohol.

[vaxn8]

EtOH is an abbreviation for ethyl alcohol. Et for the ethyl, and OH for the hydroxyl group that makes it an alcohol.

I would say unrelated to the alcohol. Was it manufactured for a pharm company that is licensed and approved to sell in the US, or is it a mfg who sells to foreing countries? My guess would be the latter, and different companies have different ideas of what constitutes good manufacturing practices. There are very strict regs in the US telling each company how to do everything and how accurate each dose must be and how many must be tested to ensure the right dose is pressed. Other countries just don't have the same regs unless they are trying to get it through the US FDA.

I'm not in anyway saying the US is the only county that enforces drug mfg safety- lots of the bigger, more developed ones have their own standards. I'm just personally familair with the US's guidlines and really doubt this Thai manufacturer is quite up to those standards.

There isn't a specific effect between tramadol and alcohol, other than potentiating or increasing sedation/CNS depression, ect.

[tptptp]

Thanks guys, or gals rather.....I had heard really good things about the quality of this thai stuff, i guess perhaps maybe its not the full dose it says it is....

I originally trhough if anything the alcohol would potentiate it but then thought that maybe it would prevent him from feeling the buzz, he gets like a whole body feels good buzz, and hes a hardcore drinker

You guys think they use unsafe inactives in other countries? thats always worried me

[flipside]

Now see, i was thinking that since tramadol is weak for me at least i terms of recreational value, andthat if the guy was truly drunk that he may not have been able to tell if he was feeling the tramadol at all.

As for foriegn countries and safety, I would agree That thailand is probably not up to the same strict regs. Always a chance when ordering from another country. Now Europe or somewhere like that I would not worry.

I agree with V that normaly the Alcohol would potentiate the trams but like I said for me they are pretty weak and if he was that drunk, any effects may have slipped right by him .

If he has any of those Trams left have him try it without the ETOH and see if he gets the same results as last time.

[Sitar]

I would say it was caused by an increase in tolerance in the user. I've never had an issue with the quality of overseas goods. Not that something couldn't happen, but I think the obvious answer is tolerance.

[flipside]

I would say it was caused by an increase in tolerance in the user. I've never had an issue with the quality of overseas goods. Not that something couldn't happen, but I think the obvious answer is tolerance.

The guy stated that his friend had no tolerance, so I don't think that could be it.

[tptptp]

Yeah I dont think he has any tolerance, he'd done painkillers three times in his life prior, and it had been a month since. Tramadol twice and subs once....

[hovadagod]

Was he on SSRI's one time and not the other? Time release? Tramadol is weird. Careful with alcohol b/c seizures are way more likely while on tramadol

[vaxn8]

You guys think they use unsafe inactives in other countries? thats always worried me

There really shouldn't be anything "unsafe", you do have the possibility of inactives that just haven't been FDA approved or studied in the US. They wouldn't use potassium cyanide as a binder for example, but may use an artificial coloring that isn't approved over here. In the example of the artificial coloring, there are some that aren't used here because they are teratogenic or carcinogenic or have some problem like that. In the amounts used to make a tablet or capsule, it would unliely be harmful. If you want to stay on the safe side, stick to countries that have something similar to the FDA- most of the organized countries- organized is not really the word i'm trying to think of, i keep wanting to say civilized, and that's not it either. Fuck it- the non-3rd world countries!

*** the coloring is just an example i made up, there are many artificial dyes in real life that aren't approved over here because they do have problems like i mentioned above, i wasn't using a specific example though because my brain is beyond dead.