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Dexter the Meth Orphan
11-21-2006, 10:33 AM
The Basic OTC Consumption Safety Rules

First off, lets get to the heart of using DXM on a recreational basis, using the right preparation. There are seven basic rules for safely consuming OTC DXM preps. These are;

1. For the best experience, use preparations containing DXM as the only active ingredient.
2. If you must consume a DXM preparation with an active ingredient other than DXM, Guaifenesin is the ONLY safe additional active ingredient to do so with. For the sake of avoiding large amounts of nausea, gas and diarrhea, it is best to avoid Guaifenesin if you can.
3. If it is your first time dosing on DXM, do not go over 200 mg. (I suggest that you start with a dose of not more than 150 mg) This is to make sure that you are not enzyme deficient and that your body will safely be able to break down a recreational dose.
4. Once you have established how your body breaks DXM down, increase your dose by no more than double your last intake. Example: you start with 150 mg, your next dose would best be 300 mg. I would recommend to people that are unsure after having dosed 150 mg to instead step up 50 or 60 mg at a time…for your safety and sanity.
5. NEVER repeat a dose until at least 6 hours have past since your last dose, or the effects of the dose have subsided or you have previously taken the total amount that the doses would equal.
6. DO NOT drive while under the influence of DXM, period.
7. For your first trip, have a “trip sitter” or at least a responsible person in the house with you that you know will not be leaving you for 6 hours or so. After that, use your best judgment. And for god sakes, if you are a cutter HIDE THE SHARP OBJECTS!

A Basic Description of Dextromethorphan

Dextromethorphan is a “dissociative anesthetic” which puts it in the same category as Ketamine and PCP. It replaced codeine phosphate in cough preparations in 1958 as a non-addictive antitussive substitute. DXM is a stereo image of Levomethorphan, an opiate pain killer, and as such it is technically a synthetic opiate. There are no recorded cases of physical addiction to DXM, only random accounts of frequent users claiming to be mentally addicted. I have used Dextromethorphan recreationally for many years, and have experienced no lasting side effects or mental addiction.

DXM experiences are separated into plateaus, but I urge anyone that is interested in the drug to focus more so on their individual take on the drugs effects rather than the plateau mg/kg list. This is due to the difference in how each individual handles DXM, and for safety sake, will allow you to more properly pin point an effective dissociative dose for your personal use.

Interactions and Combinations

Drug interactions with DXM can be fatal quite easily. The following is a list of drug types to stay away from while dosing on DXM;

1. MAOIs (this can be fatal, and in most cases is)
2. Anti depressants of ANY kind (serotonin syndrome (or “SS”) can be fatal, and is quite unpleasant)
3. Anti psychotics of ANY kind (DXM is psychoactive, and this combination can easily cause a psychotic break, among other things which are not pleasant)
4. Sedatives of ANY kind (this can cause respiratory failure among other things that you do not want)
5. Ecstasy…many people use this combo a few times and have no problems…next thing you know, the honeymoon period is over. (causes SS, irregular heart beat, severe hyperthermia and all the things that E causes by itself but FAR WORSE and it can be fatal)

DXM and alcohol can be used together, but if you are not well versed on the effects of DXM or the mixing of the two I suggest that you use caution on the amounts of them that you mix. Blackouts are very common when this combination is used, and while under the influence of a fair amount of them, you are NOT in control of your actions by any means. Use caution with this combination if you plan on using it. DO NOT use this combination in public until you have at least 100 trips and some combination experience under your belt. I can not count with all of my extremities together, how many of my friends have ended up in a jail cell or hospital detox bed for a night after using this combination and going out clubing

DXM and weed is an experience best left for the experienced DXM users. THC will make a DXM trip more potent in ways that are simply too personally defined to list here. While there are no known interactions with this combination, I suggest that you get a very good feel for DXM before trying the two together. Get a good 20 to 30 solid trips under your belt before giving this a go…it can scare the shit out of you if you don’t know what to expect from the two drugs interacting.

I am going to expand on this often. Over time, I will add to each section and also add a few more sections to help people along with a safe introduction to the wonderful OTC synthetic opiate DXM. Message me if you have ideas or see anything that you feel should be changed. Some might be wondering why I am taking the time on this when the DXM FAQ has been online for quite some time now. Simple answer is; simplicity and the fact that I have read the FAQ several times and have somewhere around 10,000 trips under my belt. What might take you 40 pages to sift through on the FAQ, I can sum up in a three page “Do and Don’t” article.

Next up: additional Interactions and Combinations, DXM side effects and the “Is This Normal?” subsection.

Hammilton
11-21-2006, 02:06 PM
antipsychotics + DXM isn't going to cause a psychotic break; they'll prevent it. Actually, if you go in with a DXM-OD, this is what they'll give you first, followed by something like Dopram and probably an antiemetic.

There's no real risk of the combination, though I would avoid seroquel with any opiate (even those lacking the effect, but having the structure to be safe) because the few times I've been forced to take a narcotic plus seroquel, I've ended up very close to an OD. Complete skin numbness, as strong as a Lidocaine patch!

Dexter the Meth Orphan
11-21-2006, 03:15 PM
antipsychotics + DXM isn't going to cause a psychotic break; they'll prevent it. Actually, if you go in with a DXM-OD, this is what they'll give you first, followed by something like Dopram and probably an antiemetic.

There's no real risk of the combination, though I would avoid seroquel with any opiate (even those lacking the effect, but having the structure to be safe) because the few times I've been forced to take a narcotic plus seroquel, I've ended up very close to an OD. Complete skin numbness, as strong as a Lidocaine patch!


You are right for the most part on that. Seroquel and a few others have known interactions with DXM. (at least from users experiences, not from a medical journal stand point) I need to change that to state seroquel and follow it up with the other types once I figure out which they are. With seroquel, what I experienced was the obvious "canceling" of most of the DXM effects, but after increasing the DXM dose I found that the DXM canceled out the seroquel and made for a very confusing experience. What can cause a psychotic break is when a newer user (not understanding the effects of each dose very clearly) doses again because they don't feel any effects from the DXM. When you start stepping up the DXM dose eventually it will cancel out the antipsychotic and the DXM effects will hit you head on.

Doxapram hydrochloride for the respiratory depression, and the antiemetic to stop the nausea and or vomiting...I understand those and the antipsychotic administration. For the most part, unless the patient is truly that far in on a DXM trip the vomiting and nausea not would not be a problem. I think the standards of treatment of a "DXM OD" (more apt DXO OD but we won't get all technical) have probably changed quite a bit in the last few years or so. The largest percentage of DXM OD is due to Coricidin Cough and Cold abuse. Reason being, the CPM and DXM in the preparation use the same liver enzyme to be metabolized. The ratio of DXM to DXO becomes elevated within the bloodstream, and DXM is pretty neurotoxic...the longer it goes without being converted to DXO the worse off. Pure DXM OD is one thing, but a lot of health care folks generally only get to see kids loaded up on DXM and CPM. (which is a deliriant, so sure without an antipsychotic, the person would just have to be strapped to a bed for 6-8 hours)

I'll get that changed up a bit, but in all actuality, a person can suffer a psychotic break by mixing the two. Especially for new comers that simply think their first dose didn't do anything, so they take more and end up canceling out the antipsychotic effect only to have the DXM trip take a hold then.

AWOL
11-21-2006, 03:25 PM
Seroquel + DXM = my 5 day stay in ICU and very near death.

If you go to the ER (I don't know why you would) from DXM alone I'm almost certain that they will not give you an antipsychotic to counter-act the DXM. I've been prescribed a fair share of different antipsychotics and combining antipsychotics with DXM is just a really bad idea.

Dexter the Meth Orphan
11-21-2006, 03:48 PM
Seroquel + DXM = my 5 day stay in ICU and very near death.

If you go to the ER (I don't know why you would) from DXM alone I'm almost certain that they will not give you an antipsychotic to counter-act the DXM. I've been prescribed a fair share of different antipsychotics and combining antipsychotics with DXM is just a really bad idea.

Couldn't have said it better...I think in the ER, antipsychotics are probably used to counter the diliriant effects of CPM which are made worse by the DXM.

jacky
11-25-2006, 12:52 AM
I used DXM every day for over a year in doses from 75-350 milligrams depending on if I wanted to use it to counter act opiate dependence side effects, or if I was going to get high.

when I quit I noticed obvious withdrawl effects, spatial disorientation, headrushes, lack of energy, depression. The reason I quit is because the stuff was wearing me down, I was noticing some definite mental disturbances. It wasnt hard to quit, not like opiates, but the withdrawl was annoying, and getting back to just taking opiates wasnt as easy as I thought.

I cannot take the stuff anymore....I took only 120 milligrams spread over 12 hours a few weeks ago, and was sick as shit the whole next day, it was a reaction that I have never had before....but I did start taking DXM in 1985, and I geuss that I had my time with the compound.

DXM can have some amazing effects, and also can be used to counter act things like constipation with opiate intake.

mentally it can be addictive, and also in my case I felt some definite physical effects when quitting it after a years use.

Dexter the Meth Orphan
11-25-2006, 02:59 PM
I used DXM every day for over a year in doses from 75-350 milligrams depending on if I wanted to use it to counter act opiate dependence side effects, or if I was going to get high.

when I quit I noticed obvious withdrawl effects, spatial disorientation, headrushes, lack of energy, depression. The reason I quit is because the stuff was wearing me down, I was noticing some definite mental disturbances. It wasnt hard to quit, not like opiates, but the withdrawl was annoying, and getting back to just taking opiates wasnt as easy as I thought.

I cannot take the stuff anymore....I took only 120 milligrams spread over 12 hours a few weeks ago, and was sick as shit the whole next day, it was a reaction that I have never had before....but I did start taking DXM in 1985, and I geuss that I had my time with the compound.

DXM can have some amazing effects, and also can be used to counter act things like constipation with opiate intake.

mentally it can be addictive, and also in my case I felt some definite physical effects when quitting it after a years use.

This is probably the worst I have heard in a while from someone that has used for an extended period of time. I have yet to have any bad side effects and I have been at it for longer than you. DXM is a personal drug though...it picks and chooses who it likes.

Flagg
12-06-2006, 08:45 AM
5ml Delsym = 30 ml DXM. Found this out the hard way yesterday :confused:

Dexter the Meth Orphan
12-06-2006, 01:34 PM
5ml Delsym = 30 ml DXM. Found this out the hard way yesterday :confused:

Yeah, each 5 ml dose has 30mg of dextromethorphan polistirex in it. However, being that the polistirex compound makes the DXM time released, the come up is very soft and the trip lasts MUCH longer. Even experienced DXM users shy away from this stuff a lot of times, because the trip length can be almost unnerving. This can be used to add a bit to a previous doses effects, but feel out your dose before you go all in with it.

Sorry it's taking me so long to get stuff updated in this thread, I have been really busy as of late.

robojunkie
12-06-2006, 10:07 PM
Dexter, one of the few opiophiles I've seen who does dxm for dxm and not just for tolerance/withrawal attenuation and potentiation. Can I add a couple of suggestions from of fellow robojunkie (get the name?) I have probably robotripped somewhere around at least 500 to a 1000 times (hard to really remember anymore) but most of it was between the ages of 17 and 20 and I would take around 500 to 750 mgs in one dose day after day after day. I don't know how long/often you do it but beware the loss of robo "magic" after about two weeks in a row. Can't be beaten by doing more (I'm sure you probably already know this).

But the worst part of daily robing is that after several months when you stop out of frustration that it just don't work and you've gone "sigma" you enter this state where you essentially feel like you have permanently damaged you brain (ability to think, remember shit, speak words you're thinking, depression, etc.). This seems to gradually pass in 6 to 9 months in my experience (about how long it seems for the dxm to work again...hmmm) but it really depressed the hell out of me that I though I was brain damaged robo-freak at 18 until I started to notice this shit get better. I'm not saying it's that disputed Olney's lesions shit as those experiments involved epic doses and you recover but heavy robotripping is best done like any other psychedelic-type substance: no more than once a week. (This doesn't apply obviously for potentiation doses, I believe).

And be very fucking careful with opes if you're really hitting the dxm in dissociative doses, from experience and reading people have done amounts of H that were decent but not powerful, then did same shit from same bundle and OD'd.

Chemical_Boy
12-06-2006, 10:13 PM
antipsychotics + DXM isn't going to cause a psychotic break; they'll prevent it. Actually, if you go in with a DXM-OD, this is what they'll give you first, followed by something like Dopram and probably an antiemetic.

There's no real risk of the combination, though I would avoid seroquel with any opiate (even those lacking the effect, but having the structure to be safe) because the few times I've been forced to take a narcotic plus seroquel, I've ended up very close to an OD. Complete skin numbness, as strong as a Lidocaine patch!

Seroquel + DXM = my 5 day stay in ICU and very near death.

If you go to the ER (I don't know why you would) from DXM alone I'm almost certain that they will not give you an antipsychotic to counter-act the DXM. I've been prescribed a fair share of different antipsychotics and combining antipsychotics with DXM is just a really bad idea.

Couldn't have said it better...I think in the ER, antipsychotics are probably used to counter the diliriant effects of CPM which are made worse by the DXM.

If they give you antipsychotics to calm you down, I doubt that they would use the atypical anti psychotics. I think they would be more likely to give you Haldol or something that has a completely different mechanism than Seroquel or Abilify or Zyprexa.

robojunkie
12-06-2006, 10:25 PM
I once did somewhere around 1400 mgs (not a true OD as I think that's somewhere around 3000 mgs) and they just force fed me activated charcoal, but I was awake though. I'm not familiar with any specific "dissociative antagonist", guess it would have to be small enough to fit in calcium-ion channel without blocking it, right?

Dexter the Meth Orphan
12-07-2006, 10:22 PM
If per say a person was that bad off, naloxone has been used to antagonize the CNS and respiratory depressive effects of dextromethorphan. The recommended dose of naloxone for dextromethorphan
induced CNS depression (to my knowledge) is usually started at 0.4 to 1.0 mg, IV in an adult with 2 to 3 minute dosing repetition as needed. I am sure that there are other methods, location dependant, for this however.

kidding
12-09-2006, 03:01 PM
I would just like to say that this thread is really excellent and there are a lot of people who I wish would just read it and use some common sense... it's so frustrating sometimes when people get fucked up over something easily avoidable (like the "make sure DXM is the only active ingredient" thing). I'm looking forward to reading updates on the manual... it's well written and easy to read... and bravo to you for making it. Thanks.

Dexter the Meth Orphan
12-09-2006, 04:32 PM
I thank you for being so kind. Just so that folks know, the "Next up: additional Interactions and Combinations, DXM side effects and the “Is This Normal?” subsection" is going to be up soon. I have been really busy lately. Sorry all....

AWOL
12-10-2006, 12:20 AM
If they give you antipsychotics to calm you down, I doubt that they would use the atypical anti psychotics. I think they would be more likely to give you Haldol or something that has a completely different mechanism than Seroquel or Abilify or Zyprexa.

That could be, I obviously don't know everything about everything and all situations. I'm just going from personal experience. Everyone I've known to end up in the ER from DXM was pretty much just put on some saline IV, given a piss test, and watched over. If they're completely gone they'll get strapped down till they calm down, though I've only known one person to be put in restraints and it wasn't from drugs.

Dexter the Meth Orphan
12-10-2006, 11:54 AM
That could be, I obviously don't know everything about everything and all situations. I'm just going from personal experience. Everyone I've known to end up in the ER from DXM was pretty much just put on some saline IV, given a piss test, and watched over. If they're completely gone they'll get strapped down till they calm down, though I've only known one person to be put in restraints and it wasn't from drugs.


This is what normaly happens, but kids on Coricidin are sometimes given AP due to the CPM mixed with DXM. CPM and DXM can cause you to do some really fucked up things, and when you come to you don't remember a bit of it.

PantyShot9
12-24-2006, 09:03 PM
I can't wait to read the updates man great job.

Dexter the Meth Orphan
12-26-2006, 05:36 PM
I can't wait to read the updates man great job.

Thank you :D