Is Morphine water soluble?

[mamasou]

Hi,

I hav been wondering whether Morphine in its natural form (in opium nad pods) is water soluble.

I think it should be since poppy tea is made with a water extraction and opium is refined by dissolving it in water and letting the solids settle.

So what does theory says??

Anybody knows?

[chemboy7]

I hav been wondering whether Morphine in its natural form (in opium nad pods) is water soluble.

Yes, the Morphine in Opium and pods is water soluble.

[Narkotikon]

Yes, the morphine in the pods via tea or extracted opium is water soluble. I've read that there are different types of morphine in the pods (morphine, morphine sulfate, morphine hydrochloride). From what I've read, morphine in it's natural state is not very soluble in water, but very soluble in alcohol, whereas the morphine sulfate and the morphine hyddrochloride is soluble in alcohol and water. I think warm / semi-hot water works the best, but I wouldn't use boiling.

[mamasou]

Thanx!

But would anyone have any facts on what the actual figures are (solubility by weight in water).

Also what is the state of morphine in its natural, mysterious form (inside opium and pods)??

Is it a salt, an acid, a base or even something else?

[Narkotikon]

Thanx!

But would anyone have any facts on what the actual figures are (solubility by weight in water).

Also what is the state of morphine in its natural, mysterious form (inside opium and pods)??

Is it a salt, an acid, a base or even something else?

I think there are differnt types of morphine in the pods. Morphine I think is a base, and then the Morphine sulfate and hydrochloride would be salts /acids, but I could be wrong. I know that there is a lot of meconic acid in pods, and I think that somehow combines with the morphine to produce something too, but again I could be wrong. I'm not a big chemist.

[superman]

Salts are water soluble. Freebases are not.

alkaloids are molecules that can be both salts and freebases. which it is depends on the pH of the solution.

while most alkaloids only form salts below ph 7, morphine will form a salt at both high and low pH's, only forming a freebase pH 8.5. this makes it very easy to isolate from the other poppy alkaloids.....

ok now i want some morphine........