Best Anti-Depressant

[Special-K]

Can anyone tell me what's the best Anti-Depressant out there (on the market)?

[antigonemuse]

this depends on your DSM, medications your currently taken, interations you have had...

some swear by them, some have sworn them off... My favorite antidepressant... opiates, works everytime...

but seriously, your best bet is to discuss this with your psychritrist. If you are worried about weight gain, welburtrin, celixa, eleville (pardon my spelling) may not be the way to go. I have had alot of luck with Prozac. but this too isnt for everryone.

good luck

[chemboy7]

That is going to vary alot person to person, drug to drug, disorder to disorder... I would say to avoid MAOIs like they were the breath of satan, SSRIs and Tricyclic drugs suck equally well but may help you, and Benzodiazepines would be my first choice (and probably your doctor's last). Benzodiazepines are wonder drugs when it comes to the likes of curbing anxiety and depression... shit, Benzodiazepines are good for whatever ails you, give you a decent buzz and potentiate Opaites too.

[alowishus]

I loved to see a doc handing out benzo's for depression, he'd have a line at his door.

















(with me at the fornt of the line)

[bodangly]

I just got put on Paxil, but to be honest I'm skeptical that its going to work. My depression is pretty bad and I just can't see this pill changing things for me. Of course I hope to krishna it does. Haha jk I don't believe in krishna =D

[superman]

effexor didn't work for me and it had so many side effects that i am unwilling to try another SSRI.

gabapentin offers unsustainable relief(once or twice a week), opiates and amphetamines work awesome for me, and modafinil is simply fantastic! modafinil gives me 2-4 months of alleviation after which point i must take a break of a month or two before the effects are worth while again.

good quality homemade(for that extra saatisfaction:) hash or oil always puts a smile on my face

in my experience however opiates are the only thing that always does the trick and is completely sustainable and affordable.

[chemboy7]

I just got put on Paxil, but to be honest I'm skeptical that its going to work. My depression is pretty bad and I just can't see this pill changing things for me. Of course I hope to krishna it does. Haha jk I don't believe in krishna =D

All Paxil ever did for me was turn my piss dark oragne (of course I was using it for anxiety, not depression). I got put on Celexa and that stuff made me sick to my stomach like all day with a nasty hangover feeling in my head, never could get used to taking them. Upon several visits I finally got bumped up to Benzo thearapy (first Xanax, then Valium) and I sorely miss those scripts, nothing worked like the Benzos... I would recommend them to anyone with anxiety, depression, or emotional problems.

[freedomclub]

Opiate replacement therapy.

[bodangly]

Benzos work, but I hate the feeling of being on them all the time. Best anti depressant = opiates

[The_Highwayman]

I have been on almost everything from prozac to risperdal for my depression and the Wellbutrin has worked the best.

To go "off-topic" the combo of drugs to make me feel like SuperMan for the first time in my life is Buprenex and steroids, no lie!!!!

[renton]

SSRI's usually arent that effective, none did anything for me. The old school ones work best for me but they usually have a ton of side effects but for me it's a choice of that or wanting to kill myself. Also one thing doctors usually resort to for really bad cant get out of bed depression is the new antipsychotics. Zyprexa is probably top of the list but it costs a small fortune and isent covered by most medical plans. I'd be carefull of benzos since there similer to alcohol and can make you feel worse over time. Opiates always seem to work for me and there great for depression or anxiety. When's the last time you heard of a addict shooting themselves? But almost all suicides have alcohol in there system when they do it.

[alowishus]

To go "off-topic" the combo of drugs to make me feel like SuperMan for the first time in my life is Buprenex and steroids, no lie!!!!

Never heard of buprenex before, just did a little reading on rxlist, sounds good, really liked what it said about "....and its low level of manifest (http://javascript<b></b>:defwindow('manifest')) physical (http://javascript<b></b>:defwindow('physical')) dependence."

Still though most likely not the easiest thing to get.

[Opiyum]

Opiates are the best anti-deppressant, but I thought we already knew that.

[vanilla_mlkshake2007]

Benzos work, but I hate the feeling of being on them all the time. Best anti depressant = opiates
I agree the best anti depressent is opiates but then again I just started on Geoden which seems to be working very well I am on 80 milligrams a day but take only 40,becase it makes you a lil dizzy,and if you have sleeping problems they should be gone although this depends on each different person.I was on serequel and gained so much weight it was unreal Although the drug works well I would rather be thin and depressed then fat and happy.Just my opinion.Hope this helped!

[Phluck]

Never heard of buprenex before, just did a little reading on rxlist, sounds good, really liked what it said about "....and its low level of manifest (http://javascript%3Cb%3E%3C/b%3E:defwindow%28%27manifest%27%29) physical (http://javascript%3Cb%3E%3C/b%3E:defwindow%28%27physical%27%29) dependence."

Still though most likely not the easiest thing to get.


Never heard of it? People talk about it here all the time. It's buprenorphine, suboxone, subutex? Sound familiar?

It's an opiate, basically, that's the dependence. But it's now often being used instead of methadone, for a variety of reasons. I won't go into details 'cause there's tons of information all over this site, and google or wikipedia. It doesn't sound like it's that difficult to get, but due to some oddities with bupe, I don't think you'll be able to enjoy other opiates while you're on it... but it could be an escape from the up and down of withdrawal, if you're interested.

[Frontier Psychiatrist]

Can anyone tell me what's the best Anti-Depressant out there (on the market)?

oxycontin

[The_Highwayman]

I can tell you that most doctors (even pharmacists) shy away from the buprenex .3mg ampule, because it is an injectable. I am open with my doctor about my past steroid use, so he knows I know how to proerly load a shoot a syringe, becuase without proper knowledge you are asking for trouble

[alowishus]

Never heard of it? People talk about it here all the time. It's buprenorphine, suboxone, subutex? Sound familiar?

I never stray in the the buprenorphine, suboxone, or subutex forums, so that's why I've not heard buprenex talked about.
Are the others just IV/IM also, it's here nor there, but that's what I was reading about the buprenex.

[bodangly]

Also temgesic comes in .2mg sublingual bupe tablets as well as .3mg ampoules, same with bunorfin

[lucas45862]

:p Swim takes 300mg of Effexor XR, Artane 2mg three times a day and Seroquel 100 mg at bedtime and seems to being doing just fine with his self!

[Paregoric Kid]

5-HTP, tramadol, bupropion, l-tryptophan, opiates/opioids, amphetamines

[HistoryofMadness]

wellbutrin and ptea, careful with seroquel or zyprexa if you don't need them, they're dopamine / seratonin antagonist I THINK and when my doc tried them (not at the same time) for sleep aid, it totally reversed the last month of treatment (or at least it felt like it)... I was quickly taken off...

[Ash Man]

Swim has tried Elavil (amitrptiline), zoloft, and lexapro for anxiety and depression. None of them really has worked. Swim still takes Elavil 100mg nightly helps sleep. Hydro use around 60mgs worked real good until swim now has a tolerance. Tried the tea twice with no results except more depression because it did nothing probably due to tolerance from the hydros. Southwest OK docs are stuck up when trying to score but they sure like the 110 bucks from an office visit. If anyone lives in SW OK PM me for lunch or something, Im new to the area.

[Hammilton]

Actually, benzo's of the xanax type (I forget the name of the family) are very good at relieving depression. There's actually one on the market- not in the US though, that is marketed for depression.

[Mokelly]

Can anyone tell me what's the best Anti-Depressant out there (on the market)?
fresh air

[cori]

ok so im going to a shrink to talk about this depression and for lack of a better word... indecisiveness, lack of confidence, a procrastination that seems to be self defeating... i dont know ive tried done for depression and aside from nodding at work it worked *obviously great* but something about using a extremely addictive drug that is often said to be used in last ditch efforts told me maybe i should try something else. after 3 weeks of done i tapered off and well.
the question...

Should i tell the shrink about my illicit drug use?
i mean i want help and this could be part of the source of problems but definitely wouldn’t want to thwart any chance of ever getting something good.

[cori]

Ok so i just got back from the shrink and i gotta say i feel like the doc was like ok... ok... ok here is a script for wellbutrin xl and turned me around and kicked me out there door. Oh but not after the 250$ fee for the visit- well with my insurance it will prolly be like 50$. but wellbutrin isn't that what they give you to quit smoking. did i just get prescribe and psych equivalent to tylenol or something?

[LayinLow]

I was on the highest dose of prozac you can take for about a year (80 mg's I believe) it was OK, I stopped it on my own, didn't really help that much. To each his own though. Opiates are defiantly my anti-depressant... as well as pot seldomly.

[john_doe]

Opiates are a great anti-depressant WHEN USED CORRECTLY and NOT abused. When you are on an opiate binge it actually makes you more depressed. When I take opiates at a fixed dose, I crave more and more. But then, when I have more, I realize I don't really feel that much better and the wanting is just an obsessive thing in my head. I feel like a bad person when I indulge and I fall asleep and forget about it and wake up and indulge again. It's a vicious cycle. One i'm trying to control.

Opiates do well as an anti-depressant for most people but you have to use them right, without OD'ing or getting blasted. I think that TRAMADOL would be a good anti-depressant for people who aren't opiate dependant. It would only be used when the depression is severe and resistant to other non-addictive forms of treatment. I think that Tramadol holds great promise for many depressed people. But it may be abused by them if they have druggy tendencies so I'm not quite sure. All I know is if you could find a way to not have people abuse it, you would be able to help alot of depressed people. Instead of harming them. I take an SSRI called Fluoxetine (Prosac, Prozac) and it works alright, it is far from a cure but it keeps me from being as angry as I used to be. It keeps me pretty calm and happy most of the time. It didn't suck away my personality either. I barely noticed it working at all. In fact I didn't notice until about a month and a half after I started taking it. Then I finally noticed that I wasn't having fits and flipping out on family and crying as much and being so sad. It did take away some of my feelings. I don't care about things as much, including people sometimes. But I love my family and wife very much. I act very selfish sometimes and treat my wife poorly and I inherited this from my mother. Her father was very abusive. It's the Scottish temper or something i'm not sure what exactly. All I know is, I can't control my anger sometimes and when people fight with me I fight back 20 times harder and have to win all the time in any battle i'm in. Sometimes I enjoy hurting my wife too and we have been married for a long time now and I still haven't changed. I don;'t hurt her physically but I call her names and sometimes I will throw food at her and yell at the top of my lungs. We were driving one time and she was yelling at me about bills and I just snapped and kicked her out of the car and gave her money to take a cab. IT was dowtown not in a crummy neighbourhood or anything but I just can't stand it when a woman yells at me it makes me snap. I don't like people yelling at me. It drives me CRAZY! lol.

So yah, Prozac works somewhat well. And I've tried Wellbutrin, Effexor, Zoloft, Paxil, Amitryptyline, Imipramine, and that other Trycyclic Parnate? Partridge? haha and Serzone, Desyrel. The one I would love to try is the DEPRENYL patch. Or just the pill. I am interested in SELEGILINE I have heard it is a miracle drug but It could be b.s. I just think It has lots of potential because i've read so much good stuff about it's anti-depressant and disease fighting effects. I have also been on SEROQUEL which did nothing. The doctor told me to take it twice a day so I took the 50mg pill before bed on the day I filled the script and within 40 mins I was out cold. So I couldn't take that during the day. I don't know how anyone can take it during the day. It puts you into a coma for 8 hours!!! Same with Trazadone, they both feel similar. Risperdal is garbage too, makes you pass out and sucks your happiness and feelings out as well. It antagonizes something in your brain because your happiness and emotions just dissolveand your a zombie!! Thats all i have to say wohoo!

****** THIS SOUNDS STUPID BUT, EAT ALOT OF FRUITS, TROPICAL FRUITS AND AMERICAN TYPE FRUITS ORANGES APPLES WATERMELON CANTELOPE HONEYDEW MELON GUAVA STARFRUIT PASSIONFRUIT PINEAPPLE KIWI. Eat all of those sort of things and make sure to eat some veggies too particularly SQUASH (mmmm sosweet like candy), SWEET POTATOE ZUCHINNI CUCUMBER LETTUCE etc. Maybe buy a few Pomegranates if you like them. This will boost your intake of natural anti-depressants from fruit. They have more than you think. A good meal of fruit and veggies can boost your brain in a good way :) But it's not the only thing. Still get meds from a doc to help. All those things together can help. Live a healthy lifestyle!!!

[Opiyum]

Live a healthy lifestyle!!!

You realize this is a website for Junky's.

I agree with you actually just found it funny at the moment. Its a good sign that your opiate intake is not doing you any good anymore when you completely stop taking care of yourself in any way. What we can be forced to do is shitty but thats the way it goes.
I try to eat as many good foods as I can. Easier for me, it may be, seeing that im a chef and get free food six days a week but its something i try and maintain during unemployment.
One thing on the Anti-depressant tip. I always sleep in a little more when taking opiates. For obvious reasons but what I wonder is when your taking opiates on a daily basis you are, undeniably, going to sleep more when you do sleep. I know sleeping alot can be a sign of depression and I wonder if it could almost be considered a side effect of opiate use. THe effect being over sleeping which inturn maybe helps to enable the depression among other things....
If you made it through that congradulations. I dont know what it said. so dont ask.

[superman]

modafinil is a great antidepressant IMO. very speedy

[psychotiKK]

modafinil is a great antidepressant IMO. very speedy

modafinil is crap. I got abunch of samples just laying around cuz I couldn't do it more than once.. it just made me feel worse. Same thing with Wellbutrin..

I take Paxil CR as my anti-depressant and I'm still always depressed, but I'd probably be worse without it. Smoking weed at night helps relax you and ease your mind.. but it's not great if you're depressed. Opiates work wonderfully as antidepressants, until you form a habit or become addicted, then your life just becomes more complicated. Amphetamines work alright.. but then there's the comedown and in the end they can just make you more depressed. Different strokes for different folks I guess. The best way to not be depressed is to make yourself so busy, that you don't have time to sit and think about it. I'm depressed all the time.. with the exception of good things happening to me in real life or if I'm on mood-elevating drugs. The reason I'm depressed is because I lack a social life, friends, girlfriend, ect. I used to have a very active social life with a wonderful girl but that all changed. Why do you think I became addicted to opiates in the first place? I wanted to numb my emotions and feel good.. partial agonists like Suboxone/Subutex are great anti-depressants even if they don't get you high. I always feel better after having my daily suboxone. Klonopin helps too if you are extremely stressed out or anxious.. and it makes me more social.. depression fucking sucks and it seems I can never really get rid of it. I'm to the point where I feel suicidal and just don't give a fuck anymore. If i wasn't on suboxone I'd guarentee you I'd relapse. Back to pods, back to heroin, vicodin, oxys, whatever the fuck i can get my hands on..

[Seedy]

I seriously believe the best way to combat depression is good diet (possibly enhanced by natural suppliments) and regular exercise. Read up on natural shit like bee's pollen, royal jelly, noni, gingeng, 5htp, pssionflower, st john't wort etc. Seriously, you may scoff, but just look them up!

[myfaceitches]

Actually, benzo's of the xanax type (I forget the name of the family) are very good at relieving depression. There's actually one on the market- not in the US though, that is marketed for depression.

Alprazolam

Yeah, pretty much any of the benzo's will cure your depression problem, FOR SURE. But, only temporarily though. Benzo withdrawals suck and can be lethal...

[Zoop]

I've been doin a lot of wellbutrin XL, 300mg tablets crushed up and sniffed. For me, it is a pretty strong stimulant. Speedy as hell. Very little comedown, nothing like the soul-crushing emptiness that I feel when coming off amphetamine or coke. I can actually go to sleep after doing like 1,000mg of bupropion. I always wash out the nose afterwards too.

But lately, I have found that I get extremely irritable when doing that, and depressed too. Wellbutrin is not a good antidepressant for me, but it's fun, though.

So, I have just gone back on zoloft, which I took for over ten years straight. I think my brain must have re-wired itself so it just uses zoloft as a neurotransmitter, because within 2 days of being back on zoloft I feel fucking great. I didn't realize how depressed I had gotten in the last six months without it.

So, my vote, for a real-live antidepressant, is ZOLOFT! At least 100mg a day, though. My vote for "most abusable antidepressant" is WELLBUTRIN - pref. the XL tablets because they have a lot more of the drug in 'em, and you can crush 'em up and toot 'em. I definitely have to chill on that for a while though.

Thanks for listening (reading).

[HistoryofMadness]

I seriously believe the best way to combat depression is good diet (possibly enhanced by natural suppliments) and regular exercise. Read up on natural shit like bee's pollen, royal jelly, noni, gingeng, 5htp, pssionflower, st john't wort etc. Seriously, you may scoff, but just look them up!

you have obviously never had clinical depression. i tried all that shit and NADA. i agree that people get fatigue from being out of shape, and ennui for being unenlightened, but there's a yawning canyon's worth of difference between those and real, bonified, sure-fire depression.

[Seedy]

you have obviously never had clinical depression. i tried all that shit and NADA. i agree that people get fatigue from being out of shape, and ennui for being unenlightened, but there's a yawning canyon's worth of difference between those and real, bonified, sure-fire depression.

You're right there. I guess what I'm getting at is the ridiculous number of people on antidepressants who really just need to step back and look at their way of life. You know, the people who live on shitty chemical filled processed food, coffee & alcohol, who work way too much and get fuck all exercise and wonder why they feel shitty all the time. Then instead of recommending a change in lifestyle, their doctor (and they) take the easy way out and try to balance it out with more chemicals. Fucking western medicnie!:rolleyes:

[Paregoric Kid]

hey no one ever said these drugs treat every form of depression ever. some people won't respond to any of those treatments, that doesn't mean they aren't good choices for other people.

[HistoryofMadness]

You're right there. I guess what I'm getting at is the ridiculous number of people on antidepressants who really just need to step back and look at their way of life. You know, the people who live on shitty chemical filled processed food, coffee & alcohol, who work way too much and get fuck all exercise and wonder why they feel shitty all the time. Then instead of recommending a change in lifestyle, their doctor (and they) take the easy way out and try to balance it out with more chemicals. Fucking western medicnie!:rolleyes:

true man, its a sham and a shame... git off yer ass, that's my doc's main treatment philosophy... she offers a minimal chemical intervention, and then goes into behavior, nutrition, and excersice... imagine that, and she's American, AND a pharmacologist!

anyway, its like diabetes (the kind you get from eating too much sugar) you can treat it AND work it off AND prevent it (from getting worse or coming back) all at the same time..

but of course PK's right too, I mean everyone's different, or at least there are many different kinds that people fall into, and ennui is the worst, from what I've seen, because its a learned helplessness, eh?

[Ragdoll]

This was posted a long time ago, but I just saw it.

I've been on all of the ssri's, plus a tricyclic or 2. The ssri's are definitely the ones, and which one to use really is an individual thing. For me, either Celexa or Lexapro have worked very well. Zoloft does weird things (motion oddness and racing heart, sleep problems), BUT some people need the speed feeling that Zoloft provides...for me, it felt bad.

Whichever one works for you, though, the ssri's are the way to go for clinical depression and all it's "buddies" (anxiety, panic, social phobia, ocd, etc., etc., etc....)

Best to you.

[Chipper]

I have found ketamine to be a good anti-depressant (which is interesting since Special-K started this thread). I never feel down after a K session. I also use Olanzapine, btw

A good walk can also do wonders...

[AWOL]

What a paradox.




Just use smack, it works better.

[Flagg]

I've been doin a lot of wellbutrin XL, 300mg tablets crushed up and sniffed. For me, it is a pretty strong stimulant. Speedy as hell. Very little comedown, nothing like the soul-crushing emptiness that I feel when coming off amphetamine or coke. I can actually go to sleep after doing like 1,000mg of bupropion. I always wash out the nose afterwards too.

But lately, I have found that I get extremely irritable when doing that, and depressed too. Wellbutrin is not a good antidepressant for me, but it's fun, though.

So, I have just gone back on zoloft, which I took for over ten years straight. I think my brain must have re-wired itself so it just uses zoloft as a neurotransmitter, because within 2 days of being back on zoloft I feel fucking great. I didn't realize how depressed I had gotten in the last six months without it.

So, my vote, for a real-live antidepressant, is ZOLOFT! At least 100mg a day, though. My vote for "most abusable antidepressant" is WELLBUTRIN - pref. the XL tablets because they have a lot more of the drug in 'em, and you can crush 'em up and toot 'em. I definitely have to chill on that for a while though.

Thanks for listening (reading).

Definitely wouldn't do this. The risk of seizure is high, and this is certainly the first time I've ever heard of anyone getting off on Wellbutrin, even though it is related to cathinone, I think.

However, it's completely different than any other anti-depressant, it's quasi amphetamine so it won't really cause weight gain, and it worked for me multiple times. I kicked cigarettes on the side while on 300mg a year ago last July.

[AWOL]

you have obviously never had clinical depression. i tried all that shit and NADA. i agree that people get fatigue from being out of shape, and ennui for being unenlightened, but there's a yawning canyon's worth of difference between those and real, bonified, sure-fire depression.

Amen to that.

What a paradox.




Just use smack, it works better.

Don't be a fucking retard ya lame.