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Paregoric Kid
10-13-2009, 11:08 AM
how are these? are they worth taking IM/SC? is there any point in IV? I've heard with IM/SC tramadol you can dose up to 500mg instead of 400mg when taken orally. I imagine it wouldn't be that great due to it being stronger after being metabolized. would it be better to just drink the liquid? I imagine injection would cause faster relief of pain or wd but would take longer to reach peak effects. just curious if anyone here has had any experience with the amps.

hovadagod
10-13-2009, 11:21 AM
no experience but I find tramadol a good tapering drug. That's basically all its food for IMO....also to stave off WD's. Maybe pain relief but if I'm in real pain I hope to get a real opiate/oid.

Paregoric Kid
10-13-2009, 11:23 AM
well yeah obviously I'm talking about minor pain, nothing serious. I agree tramadol is great for wd. I've only ever used the oral tablets though.

hovadagod
10-13-2009, 11:33 AM
yea; me too. I would like to try the IM stuff.

GOLD N DIEMONDS
10-13-2009, 02:28 PM
MMM - never hear of such, BUT what does PDR recommend for ROA
being the dr./addict/junkie - me mainline
you have a sterile injectable suited for such right?
I am sure you know minor issues w. SSRIs?
But I have great pipes too, so if that issue- IM
But need big gauge and longer
ass is best IM site 4 fingers over from crack
massage well afterward
or go for pipe and report finding
STAY SAVE KID. ok

clonaze-whammed
10-13-2009, 05:03 PM
I had 100mg tramadol IV in hospital before, found it very pleasant, even had a fent patch on at the time and still felt a nice glow from the tramadol.

Seedy
10-13-2009, 05:08 PM
seems kind of pointless to me, like if you're going to go to the trouble of injecting something, why tramadol? Not that I wouldn't try it if I had one but why even bother putting a weak assed pseudo opioid in an ampule?

EleusisII
10-13-2009, 11:02 PM
Yeah, just leave it alone, or inject some real drugs.
Or is it needle-fetichism that's driving you?

It's sort of a shitty high, and really not worth the risk of seizures, ya know?

Chemical_Boy
10-14-2009, 06:02 AM
no experience but I find tramadol a good tapering drug. That's basically all its food for IMO....also to stave off WD's. Maybe pain relief but if I'm in real pain I hope to get a real opiate/oid.
Yeah... I agree with you. Even when you take enough to catch a buzz it is a crappy weak buzz. If I take ten or twelve 50mg tabs all at once, I do get some sort of buzz. To even call it psuedo-opiate is being generous. It is kind of a sweaty, wired, borderline unpleasant feeling. However five or six of them can be the difference of not being able to get off the couch cuz you are so unmotivated/depressed/run down feeling if you are in mild withdrawl. I never tried them with severe withdrawl. I don't know if the slight antagonist effect of these things would kick you into worse W/D or not. But these have been a lifesaver for me when I have a borderline habit- the kind where going without leaves you feeling shitty and useless for a few days but not full blown horid, wretched, nasty motherfuckin W/D...
seems kind of pointless to me, like if you're going to go to the trouble of injecting something, why tramadol? Not that I wouldn't try it if I had one but why even bother putting a weak assed pseudo opioid in an ampule?
Again, I would just save them for minor W/D damage control....

Paregoric Kid
10-15-2009, 10:29 AM
I want to make it clear that I'm not talking about injecting oral tablets, I'm talking about the 100mg amps of tramadol that are intended for injection. never saw them before so I thought I'd ask here if anyone has experience with it. I mean who wouldn't try them out if you had the chance and didn't have anything else. also I don't believe that it has any antagonist effects at all, I think that was some misinformation that came out when tramadol first hit the market. also if you get too many unpleasant side effects from tramadol I wonder if clonidine would cancel out the norepinephrine effects.
that is an interesting experience about the IV tramadol with the fentanyl patch.

doctor diesel
10-15-2009, 11:56 AM
[/QUOTE]It is kind of a sweaty, wired, borderline unpleasant feeling.[/QUOTE]

That's the perfect description of how tramadol feels.


[QUOTE=Paregoric Kid;428121]If you get too many unpleasant side effects from tramadol I wonder if clonidine would cancel out the norepinephrine effects. [QUOTE]

Paregoric, do you think that it's tram's action on norepinephrine, rather than its other actions, that causes the above feeling?


Doc

port rhombus
10-15-2009, 12:56 PM
Paregoric Kid: I assume these ampoules came from outside of the US?

I regularly take tramadol on top of an oxymorphone maintenance dose. I'm thoroughly convinced it's not an opioid antagonist or partial agonist, though I've seen some strange (mis)information floating around the internet to that effect. I have a feeling that may have come from some poorly worded details in the tramadol prescribing information about its ability to cause withdrawal reactions when switching from more potent opioids.

I'd be interested in trying IV/IM tramadol.

Papa Verine
10-15-2009, 01:00 PM
Paregoric Kid: I assume these ampoules came from outside of the US?

I regularly take tramadol on top of a significant oxymorphone maintenance dose. I'm thoroughly convinced it's not an opioid antagonist or partial agonist, though I've seen some strange (mis)information floating around the internet to that effect.

I'd be interested in trying IV/IM tramadol.

What do you mean PR? I've always considered Tramadol a weak mu opioid agonist, amongst other not-so-well-understood activities. Some people have argued that Tramadol is not a powerful enough mu-O agonist to account for it's effects but I can feel it just fine around 400mg. Feels like an opioid to me...

port rhombus
10-15-2009, 01:05 PM
I agree with you. I was trying to say that the effects I've experienced from tramadol are those of an opioid agonist (among other things.) There's some information floating around the internet to the contrary and I was speculating as to the source.

I just re-read what I wrote and it wasn't exactly clear... sorry.

Papa Verine
10-15-2009, 01:11 PM
I'm agree with you. I was trying to say that the effects I've experienced from tramadol are those of an opioid agonist (among other things.) There's some information floating around the internet to the contrary and I was speculating as to the source.

I just re-read what I wrote and it wasn't exactly clear... sorry.

Oh yeah, there are people here who refuse to acknowledge Tramadol is an "opioid". I'm sorry, I don't have much use for what the medical literature says about it. I can *feel* it. That's more important to me, obviously, and I don't give a damn what anyone wants to call it. I avoided the debate about the subject because I think it's silly.

Paregoric Kid
10-15-2009, 01:24 PM
doctor diesel, yeah I bet some people experience side effects caused by its action as a norepinephrine reuptake inhibitor. ephedrine and the levo isomers of the amphetamines and ritalin act as norepinpherine reuptake inhibitors and/or cause the release of norepinephrine. clonidine is sometimes prescribed with some ADHD meds like adderall or ritalin to prevent NE reuptake/release so that it mainly acts on dopamine and sometimes serotonin. I would guess it would lower some of the side effects some people get from tramadol too.

tramadol itself is a weak mu agonist but the metabolite o-desmethyltramadol is a much more potent mu agonist.