Certain oxy products higher nasal BA than others?

[Mulch]

So Swim's been doing some thinking...
For example: Would a small pill with a high dose (e.g. OC80) be absorbed better/more efficiently if used nasally due to less powder per MG than per say an OC20?
Leading up to my next two questions:
1) Does less powder mean better absorption?
2) Any one type of oxy (e.g. IR or ER) product better suited for nasal use than others due to the different fillers and characteristics of the pills?

I apologize in advanced if this has been answered before or someplace else, and if it's the case please point me in the right direction:p, if not thanks in advance for your responses:D!

[Mulch]

....hummmm maybe these aren't very good questions?:D

Like swim mentioned don't be shy to point swim in the right direction:).

Peace.

PS
Swim's a Noob :-)

[mikey5string]

"OC 20's are smaller than 80's. For the most part they grow i size as the mg gets higer. I think the difference would be negligible. As long as it contains only oxycodone there all ok for snorting. IR (immediate release) as compared to ER (extended release ie OxyContin) pills like roxis break up easier for me and are better in that respect (no coating or time release to defeat etc)

Now, i just chew them up and swallow them. Lasts longer and beter for the old septum plus for me, blowing pills makes me want to keep doing more whereas eating them the compulsion isnt as bad."

-SWIM 09'

[saveyour]

1. the membranes that are coated by oxycodone during insuffulation and cause the desired high are of a finite amount and limited space in the nasal cavity.
2. logically that leaves a finite amount of surface area to be covered by said drug.
3. therefore the higher concentration of the drug that can cover the surfaces in your nasal cavity should lead to a quicker onset of the drug.

so deductively, yes the smaller the pill size (of the same strength) should give higher absorption up the ole nose. but i think this only goes so far, as you can't get higher on a more concentrated drug than on a drug of higher dosage due to other factors like the drip's oral absorption and other variables such as how moist your nasal membranes are, etc.

i've always personally prefered the smallest oxycodone IR 30mg pills i could find (a|215 or brand) but i'm not exactly picky nowadays or anything :p

[duck]

there are more inputs into your logic than you are considering, saveyour.

by your logic, pure oxycodone would be absorbed better than oxycodone with a moderate amount of inactive ingredient (say an OC 80 in the size of an OC 40). I highly suspect they would be incredibly similar if not the OC 40 pill being absorbed better. Often, when snorting, the powder bypasses the membranes altogether and goes down one's throat...I would assume pure oxy, being so small, would go straight down much worse than the aforementioned 80mg OC 40.

Just a thought!

[runormal]

"OC 20's are smaller than 80's. For the most part they grow i size as the mg gets higer. I think the difference would be negligible. As long as it contains only oxycodone there all ok for snorting. IR (immediate release) as compared to ER (extended release ie OxyContin) pills like roxis break up easier for me and are better in that respect (no coating or time release to defeat etc)

Now, i just chew them up and swallow them. Lasts longer and beter for the old septum plus for me, blowing pills makes me want to keep doing more whereas eating them the compulsion isnt as bad."

+1. Chem them!

As for snorting them, the OC 10mgs are the ones I would pass on as they are the same size as the 40mg but only 1/4 of the oxy and it seems like a lot of powder to get through. With those I would feel like per square inch there is too much powder to filler to make it worthwhile which I think was the OPs original question.

[duck]

Yeah, the OC 10s definitely fucking suck for snorting. I snort almost all of my drugs, and those are some of the worst. Even the OC 20s are borderline too nasty.

That's why I love my 80s. Yeah, they're bigger, but something about them...they just are much better for snorting. They taste or smell or feel or something way better than the others. They feel more potent, pound for pound.

[Narkotikon]

I vote for just chewing them up and swallowing the pills. Oxy has a great oral BA. As for snorting, I would think the more oxy to filler ratio would be better (i.e., snorting a line of oxy powder made from an 80 would be better than a line made from a 10 or 20) just because you'd be snorting more filler with the line made from the "weaker" oxy pill.

Your nasal passages are only so big. The more active drug you have, the better, otherwise the filler crap is just going to take up the space that the drug could be taking up, if that makes any sense. Think about it this way: would you snort a 5mg Percocet with all of that APAP in there? I wouldn't.

As for if a high-dose oxy product has a better bio-availability than something with a lower dose of oxy, technically no. Oxy is oxy is oxy. All oxy is going to have the same BA. It's just that the stuff with more filler in it is going to be harder to snort because of the filler. Not because the BA of that particular oxy pill is different. Oxy is oxy is oxy.

[Pandora]

I vote for just chewing them up and swallowing the pills. Oxy has a great oral BA. As for snorting, I would think the more oxy to filler ratio would be better (i.e., snorting a line of oxy powder made from an 80 would be better than a line made from a 10 or 20) just because you'd be snorting more filler with the line made from the "weaker" oxy pill.

Your nasal passages are only so big. The more active drug you have, the better, otherwise the filler crap is just going to take up the space that the drug could be taking up, if that makes any sense. Think about it this way: would you snort a 5mg Percocet with all of that APAP in there? I wouldn't.

As for if a high-dose oxy product has a better bio-availability than something with a lower dose of oxy, technically no. Oxy is oxy is oxy. All oxy is going to have the same BA. It's just that the stuff with more filler in it is going to be harder to snort because of the filler. Not because the BA of that particular oxy pill is different. Oxy is oxy is oxy.

+1 on everything other than chewing and swallowing instead of snorting, but that's only because I'm a compulsive sniffer.

Good answer, take this advice! You always give awesome advice, Narko!

[Mulch]

Thanks for all the feedback fellow opies! This was swims 1st post, and swim feels it went well! Thanks again, swim's feeling really good right now, just got the best deal ever, too bad it's a one time thing, but hey be grateful for what you get:D. As swim is! Hope everyone is getting ready for a fun and safe weekend. This swim right here sure is:).

Peace!

[hydro chris]

Your nasal passages are only so big. The more active drug you have, the better, otherwise the filler crap is just going to take up the space that the drug could be taking up
good point!!

[roxi*stardust]

If you do a search on here for nasal bio-availability you will find info on why it's lower than swallowing the pill and what can be done to increase it.

[Mulch]

If you do a search on here for nasal bio-availability you will find info on why it's lower than swallowing the pill and what can be done to increase it.]

Yes, swim's done searches, and maybe swim just refuses/can't believe what swim reads...The reason why swim says this is: swim started out eating the stuff wayyy before swim even knew the drug could be administered nasally, and always got the desired effects, but to this day feels that it works best for swim nasally:D. I know, I know facts are facts, but the "fact wave" swim's surfing on is that every drug effects everybody differently. And I think we can all agree on that?:p Anyways, it's fucking Friday and time to get this party started, I hope everybody has a happy and safe weekend!! Peace

[jcmanny]

Yeah, the OC 10s definitely fucking suck for snorting. I snort almost all of my drugs, and those are some of the worst. Even the OC 20s are borderline too nasty.

That's why I love my 80s. Yeah, they're bigger, but something about them...they just are much better for snorting. They taste or smell or feel or something way better than the others. They feel more potent, pound for pound.

I used to buy this dude's 5 mg oxycodones. Man those totally suck ass for snorting. Grinding 4 pills in one line is like snorting an 8 ball of coke!