Un-Potentiators

[Sunny]

So everybody talks about potentiators focusing on what to do to lengthen and increase their high, but what keeps you from getting high or shortens duration? Taking your pill / dose right after you eat, or right before, drinking milk, ice-cream, certain medications, or even your mental state (depression, anger...). The reason I ask is that I went wakeboarding the other day and the water was sooooo cold that as soon as I hit the water my high was gone faster than my dealers stash on my payday.

[wizardofoz80]

Assholes! maybe a noob or 2

[ryan]

Haha...any strong stimulant should do the trick..

Cocaine, adderall, methamphetamine, dexedrine, benzedrine, etc..even ritalin
Even those other non-amphetamine ADHD meds are supposed to help concentration like Modanafil.

But what you are talking about (the water ruining your high) is more psychological than chemical...at least that's that I think
You can be high as fuck but if that one person starts pushing your buttons they can ruin the whole thing for you and then your mind kinda tricks you into believing that you're "coming down" and need to do more..it's a bitch.

[OxiContinKing]

Completley off topic, but Ryan, I remember when surge first came out, god it came out with all the hype in the world....

I drank the shit outta it, never really noticed if it gave me any noticable effects, since I was under the influence of some type of stimulant back then, lol, but that never stopped me from drinking it...

Do they even still sell it? I havent seen it down here in years...

And since I'm already off topic, I might as well stay there; How is everyone doing this evening?

After a long day/night at work, I've finally made it home, just popped my xanax bar (yellow), bout to hit the shower while waiting for that to kick in, then I'll meet you guys back here with a fat one rolled and a couple of double duces...

Nothing like kickin back after a sucessful day at the office...

Medicate safley everyone...

[lotus]

prednisone. it's a god awful steroid. every lung infection i've ever had they make me take the shit. shortly after i'd been stabilized on methadone i had to take it, 10 days, by the second day i was in minor withdrawal, by the 8th day i was so friggen raw my pharmacist told me to fuck it, and skip the last two days.

alcohol. beer, wine or booze the stuff makes me burn thru my dose faster than i can say good bye. mixing the two, i can feel them at war inside me and if i can drink thru the initial sea sick rocking i can carry on till the cows come home. i usually lose tho - so often that i haven't been bother'd to even attempt in a few years now - doesn't matter if it's a couple drinks or 1/2 the bottle. soon's i start to sober up i can't sit still, pupils expand to the size of saucers, then my nose starts running. just not worth it.

[HandMeSomeOpiates]

Haha...any strong stimulant should do the trick..

Cocaine, adderall, methamphetamine, dexedrine, benzedrine, etc..even ritalin
Even those other non-amphetamine ADHD meds are supposed to help concentration like Modanafil.
.
I respect your opinion but I totally disagree. IME adderall increases my buzz by at least 10%. I sometimes only have to dose once when I have some Vyvanse or Adderall XR. That said, I do enjoy the speedy effects of opiates though so maybe that's why I feel much more euphoria. Hydro and Adderall IMO are one of the best combos to start the day.

[chopstix]

Cops = worst fuckin' un-potentiators 3v4r.

[ryan]

Completley off topic, but Ryan, I remember when surge first came out, god it came out with all the hype in the world....

I drank the shit outta it, never really noticed if it gave me any noticable effects, since I was under the influence of some type of stimulant back then, lol, but that never stopped me from drinking it...

Do they even still sell it? I havent seen it down here in years...


When I first came online back in 1996, I dedicated my handle to the best soft drink ever made, Surge.
Unfortunately, it's not made in the US anymore..

I believe you can only get it in Norway, and it's called "Urge" not surge.
Around 2002, there was a website that came about, savesurge.org which actually contacted walmart, got a whole bunch of surveys and shit together and actually came up with solid proof that coca cola could have a market for surge at walmart. The walmart people agreed, however the coca cola execs declined.
It seems as though they just don't want surge to ever come back again...it's sad really.

Since I've never had the norweigan stuff "Urge" I'm not sure if it tastes the same...I would love to try some.
They have Vault now, which is alright, but I really don't think it compares to Surge at all..just my opinion though.
Also what's really strange is that in Norway, the "Urge" drink is extremely popular, holding a significant share of the drink market over there.

Their reason for discontinuing it here was because of declining sales, but shit everyone I knew back then LOVED the stuff, including myself, and still to this day there's petitions and shit at that website asking for coca cola to bring it back, so I don't believe that for one second that sales were declining...there's gotta be some kinda conspriacy here :D

[OxiContinKing]

I drink Vault on occasion, but not nearly as much as I would drink surge if I was able to buy it...


They have Vault now, which is alright, but I really don't think it compares to Surge at all..just my opinion though. Also what's really strange is that in Norway, the "Urge" drink is extremely popular, holding a significant share of the drink market over there.

And imagine that...

[PrisonHer]

Cops = worst fuckin' un-potentiators 3v4r.

that's exactly what I was gonna say.

[Pollen]

Sometimes I forget to eat or drink for a long time when I'm high until I start to feel like my high is disappearing because of it. But if I eat or drink it normally brings me back up.

[HandMeSomeOpiates]

But if I eat or drink it normally brings me back up.
That's because fatty foods potienate opiates. So grab ya a #4 at McDonalds YO! haha

[Dan Steely]

hunger and traffic and more than a couple lines of coke.

[dugwylor]

About the alcohol, I know that one has some kind of chemical fact behind it -- does something with receptors, blocks this, shuffles that, and waltzes with your dopamine right out the door. Can't remember the number of days I've been feeling so nice and think a drink will just cap it off. Somehow I manage to forget every time. Halfway through the first drink, I can feel no buzz from the liquor or beer and the opiates already grow subdued. Second drink and they're sitting in the back of the auditorium trying to shout stage directions to my increasingly confused brain until the third drink kicks them out for disorderly behavior and I'm left thinking, what the hell just happened?

Hadn't heard about cocaine -- just a little bump of great coke on a nice opiate high is absolute heaven -- but I haven't gone too far mixing the two, either...

[Thebane]

About the alcohol, I know that one has some kind of chemical fact behind it -- does something with receptors, blocks this, shuffles that, and waltzes with your dopamine right out the door. Can't remember the number of days I've been feeling so nice and think a drink will just cap it off. Somehow I manage to forget every time. Halfway through the first drink, I can feel no buzz from the liquor or beer and the opiates already grow subdued. Second drink and they're sitting in the back of the auditorium trying to shout stage directions to my increasingly confused brain until the third drink kicks them out for disorderly behavior and I'm left thinking, what the hell just happened?

Hadn't heard about cocaine -- just a little bump of great coke on a nice opiate high is absolute heaven -- but I haven't gone too far mixing the two, either...

Really? I've never noticed that about alcohol, but when I really get "euphoria" nothing seems to make it go away. When I use normal doses of opiates that don't come close to "euphoric" in any way on their own, alcohol, even just a drink or two, seems to kick the buzz up a lot.

[Restharrow]

Haha...any strong stimulant should do the trick..

Cocaine, adderall, methamphetamine, dexedrine, benzedrine, etc..even ritalin
Even those other non-amphetamine ADHD meds are supposed to help concentration like Modanafil.

I am just the opposite -- stimulants INCREASE the euphoria of opiates by 50% or more. I have to be careful, a lot of stimulants, turns on the MORE - More - More switch in my brain and I can go thru a months worth of meds in 5 days if I don't pay attention.

Now, I try and take just 10 mg. of Ritalin on the days when I take the maximum dose of opiates (about 5 to 7 days per month).

Will

[ryan]

I am just the opposite -- stimulants INCREASE the euphoria of opiates by 50% or more. I have to be careful, a lot of stimulants, turns on the MORE - More - More switch in my brain and I can go thru a months worth of meds in 5 days if I don't pay attention.

Now, I try and take just 10 mg. of Ritalin on the days when I take the maximum dose of opiates (about 5 to 7 days per month).

Will

I understand what you guys are saying, but to me, opiate euphoria peaks at the point where I am halfway asleep and halfway awake (the so called "nod") -- uppers take away from nods (for me) and therefore take away from the euphoria.

Someone also mentioned not having a drink, that's a BIG one for me...opiates cause huge dry mouth for me, and if I have dry mouth for awhile it starts to ruin my high a little bit.

[dugwylor]

Really? I've never noticed that about alcohol, but when I really get "euphoria" nothing seems to make it go away. When I use normal doses of opiates that don't come close to "euphoric" in any way on their own, alcohol, even just a drink or two, seems to kick the buzz up a lot.
I've heard a lot of people say that -- throw in a few drinks and you're up a notch -- but for me it always sedates the high and puts it in the background (just like too much weed). What I've heard is that the reason they mix well is due to a certain kind of synergy in their secondary effects that don't relate to dopamine in any way... essentially enhancing the body high. Wish I could say something a little more solid on it, but all I know is that I've got to stay away from alcohol unless I'm willing to risk putting the opiates in the back seat and turn the night into a drinking one.

[Sunny]

But what you are talking about (the water ruining your high) is more psychological than chemical...at least that's that I think


It could be more psycho than chemical, but I was wondering if because it was so cold it shocked my system or something along the lines of sympathetic nervous system versus parasympathetic nervous system. When your high and resting your body is in sympathetic nervous "mode" and when you jump in the water your now in parasympathetic nervous "mode" and using different nerves and neurotransmitters. I don't know it's probably really complicated but bottom line, I am saving my pills until I am done wakeboarding :D.

My real question was what foods should I avoid that could potentially ruin my high. Just like when I smoked weed back in the day I would drink milk if I got too high and it would kind of bring me down (although that could have been psychological too).

Thnx for the replies guys!

-Sunny

[Dolomiti]

Piracetam... and apparently it might have use in treating various addictions.

[Euphoricgirl]

First time I've ever heard that question asked..:rolleyes:

[More Feen]

Generally, when opiated, I have no interest what-so-ever in alcohol. It seems like it robs some of the nice feelings opis produce.

I'm curious how tincture of opium (Laudanum) would work for people who feel like I do. I mean, the nice chemicals in the alcohol would make someone feel pretty good, but then the alcohol itself might remove some of that goodness.

Also,

A while back, a friend I know wanted to try and treat his opiate withdrawal using preparations of Coca (something that Sigmund Freud had suggested doing). I talked about this and the results a few weeks ago. You can find that thread, if you want. His "habit" was small, W/D didn't cause vomiting, just cravings and leg cramps.

He noted that coca tea made him forget about opis for an hour or two. Then he'd drink another cup. Even after 2 days without opis, he tried his favourite opi after taking coca tea, and he did not notice the opi's effects ! It seemed to block, or over-power the pleasure center of the brain (the nucleus accumbens)!

A follow-up, this friend (more of an acquaintance) tried taking the coca preparation after getting a decide opi buzz, and the coca tea totally killed his buzz.

Maybe at the low end of opiate habituation/addiction, people are trying to get a pleasurable reward from their brain, but the drugs contained in the coca leaf tickle the brain's pleasure-centre more directly.

If one considers that coca-leaf chewers (and cocaine users) often ignore their hunger, this might be for a similar reason: eating is an activity rewarded by the brain, but under the influence of coca, the feedback loop is disrupted (eating food under coca's influence doesn't produce a directly associated reward of pleasure).

That's all I've got,

M F

[Sunny]

First time I've ever heard that question asked..:rolleyes:

And yet you have nothing to add... Hmmm:rolleyes:

[Indy]

And yet you have nothing to add... Hmmm:rolleyes:

And neither do you...don't think that just because it's your topic you can get away with posting anything less than B- material (just kidding, i'm making fun of you for making fun of her). But seriously, don't worry and relax, you don't have to make sure every post you make has "something to add" to the topic.

[SHELLEY]

getting pulled over by the cops

[EleusisII]

Getting stopped in customs with multiple old, empty prescription bottles. AND a little booklet on "Islam for beginners"
(Raised eyebrows... "Are you a... Muslim sir?")

Actually just getting the third degree from customs in general.

[resorcinol]

I've gotta strongly disagree that uppers ruin an opioid high (unless you care more about the nod than anything else).

Focalin or Adderall can stretch an opioid stash beautifully by giving you much stronger euphoria than you'd expect from the opioid dose. See my other post in this forum about this combo.

[OxiContinKing]

I've gotta strongly disagree that uppers ruin an opioid high (unless you care more about the nod than anything else).

Focalin or Adderall can stretch an opioid stash beautifully by giving you much stronger euphoria than you'd expect from the opioid dose. See my other post in this forum about this combo.

I agree with you, but for some reason I feel like the past couple of days adderall has caused my dose of methadone to wear off faster. I am not prescribed adderall, nor do I take it on a normal basis, but I have gotten ahold of a couple of 30XR's, and Ive taken one or two a day for the past 3 or 4 days.

MY SO says just the opposite though, so I guess it all comes down to your body chemistry.

And yeah, I'm more about the nod, really, besides being sick, than anything else. I dont think it is placebo though, because I am waking up in the middle of the night with my sheets fucking soaked, RLS more frequent and intense than normal in the mornings, and the sniffles and shit are a little bit further along than they normally are.

I know I need an increase, really, really bad, and I intend to ask for one, I just have to wait until I get my system cleaned out, and can pass a UA with nothing but 'done and pot. I dont even bother trying to ask for an increase if Ive got some kind of other opiates or benzo's in my system. Luckily, though, Ive passed all of my UAs (besides pot) except for one, I had 'trace' amounts of xanax in my system...

[existential_apathy]

Large crowds do it for me. Driving on opiates is one of the best feelings in the world, but being in a mall ruins it for me. I go into the mall feeling great and go out feeling mediocre. The annoying teenagers, whining babies, the overabundance of near-identical clothing stores playing obnoxious music, all take away from a good buzz. But I was never much of a fun of malls or shopping. Oddly I don't get the same result from grocering shopping.

[Sunny]

And neither do you...don't think that just because it's your topic you can get away with posting anything less than B- material (just kidding, i'm making fun of you for making fun of her). But seriously, don't worry and relax, you don't have to make sure every post you make has "something to add" to the topic.


I was just having fun, I really wasn't upset at all. maybe I should have put a smile face instead of the smirk... :D

[Deadfiend]

As I said in my other post today, No will lower a good pill, H buzz cause it takes over the benzos, GABA receptor antagonists and the same with The effects of N2O seem linked to the interaction between the endogenous opioid system and the descending noradrenergic system, then of couse theres food, the more stuff in you blood the less you are going to feel, washing, bath shower, gpomg into a pool right after a shot, or what ever your doing, this is said because it opens up your pores and in turn lets the drug to be let out of you body faster thats why mut people fix after a showerand not before or may not even take any at all when on a binge, then there are tons of other drugs to kill a buzz to a deadstop.

Note: Milk as always said to stop a tri,, not true...

Note:
anxiolytic effects of benzodiazepines are partially tolerant to nitrous oxide. Indeed, in humans given 30% N2O, benzodiazepine receptor antagonists reduced the subjective reports of feeling “high”, but did not alter psycho-motor performance.

[rosebud]

Definitely my Father in Law visiting for more than 48 hours......following at a VERY close second, my Mother in Law accompanying him. The most major ruination of any buzz-the time they came to visit and ended up staying almost 3 fucking weeks! Words cannot do justice to the buzz-kill THAT was.

So, I took care of the problem once and for all by completely alienating them after 10 years of kissing ass. On the down side, I miss their birthday presents, on the up side, I dont miss HIM, at all. Her, I can handle fine if he is not around. If he is, faw-getta-bout-it!

Worst buzz kill ever ever ever. They outta bottle him and make him into some kind of human antibuse.....Just sayen.

[Dune]

Neurontin (gabapentin) reduces the bio-availability of Hydrocodone by ~40%. I am not sure if it does this with other opi's. Lyrica might have a similar effect too, but that is purely speculation.

INTERACTIONS WITH OTHER DRUGS

For chronic pain relief, gabapentin is best started in combination with other pain relievers but after a time often the other pain relievers can be discontinued and gabapentin is effective as a sole agent.
Oral antacids will hinder absorption of gabapentin into the body by up to 20% so it is important to separate administration of these two medications by at least 2 hours.

Concurrent use of hydrocodone (http://www.marvistavet.com/html/body_hydrocodone.html) or morphine, both narcotics, with gabapentin can increase the effectiveness of gabapentin. Concurrent use of gabapentin with hydrocodone will decrease :mad: the effectiveness of the hydrocodone. (info from Drugs.com)

This info can be found by google-ing gabapentin and hydrocodone interactions.

FYI - my Dr. says that this is BS, but I have found many different sources that say it IS true.