Catnip

[existential_apathy]

One summer day I decided to toss some fresh catnip (it grows outside) into my poppy pod tea in an attempt to reduce any possible nausea and because catnip is very mildly sedative in itself. I was surprised when the tea made me a bit higher than I would have expected. I repeated it again and found that I almost always get a bit higher when I drink some catnip with my pods. I'm not sure if it's just placebo as the potency of tea is always a bit variable itself, but I thought that I'd toss this experience out. At best it doesn't hurt anything. I don't know anything about catnip or why it would be synergistic/potentiating.

[libertine]

ahahahah





hahaha ahhh

[OpiXPO]

I've been told by homeopathic(sp?) doctors that catnip is something along the lines of a sleep aid and can be used as such. So it might be possible that you really did get extra high from cat nip.

[GOLD N DIEMONDS]

YOU ARE USING
your kitty dope???
mmm- the shame
try GRIT N JUICE
never understood tea:confused:

[mikey5string]

silly junky, catnip is for cats!!

[EleusisII]

Wow... We're really scraping the bottom of the barrel when it comes to potentiators, aren't we? ;)

I've been told by homeopathic(sp?) doctors

Yeah, see those two words don't go together. Kinda like "DEA-pusher" or "Mother Teresa-Whore"
A homeopathic doctor isn't a doctor. He's a lowlife hustler who figured out that it's easier to push a load of garbage on people if you buy a fancy, but meaningless diploma.
When homeopathy was invented, hospitals were still putting leaches on people, and had them drink brandy for anathetic cause no one had thought of morphine yet. That should tell you all.

[GOLD N DIEMONDS]

Wow... We're really scraping the bottom of the barrel when it comes to potentiators, aren't we? ;)



Yeah, see those two words don't go together. Kinda like "DEA-pusher" or "Mother Teresa-Whore"
A homeopathic doctor isn't a doctor. He's a lowlife hustler who figured out that it's easier to push a load of garbage on people if you buy a fancy, but meaningless diploma.
When homeopathy was invented, hospitals were still putting leaches on people, and had them drink brandy for anathetic cause no one had thought of morphine yet. That should tell you all.

SO -I am a WEE bit slow
but are you saying
Leaches = GOOD OPIATE POTENTIATIRS???
IF so how does one go about
wear thee leach or
or use in the mxiutre, (don't mind leach eating)


ps- I check wiki so don't get all Mafia 6 on ME ass
;)

[bigNasty]

SO -I am a WEE bit slow
but are you saying
Leaches = GOOD OPIATE POTENTIATIRS???
IF so how does one go about
wear thee leach or
or use in the mxiutre, (don't mind leach eating)


ps- I check wiki so don't get all Mafia 6 on ME ass
;)
Can you smoke your used leaches to get a buzz? Or can you just chew them and try not to swallow for 10-15 minutes? Does anybody know if leaches are still good after you take them off or should I just toss them?

[GOLD N DIEMONDS]

Can you smoke your used leaches to get a buzz? Or can you just chew them and try not to swallow for 10-15 minutes? Does anybody know if leaches are still good after you take them off or should I just toss them?

I read somewhere on the net that after wearing.
plugging them is good option,
i not sure how much water to use though

[bigNasty]

just make sure to use warm water so your body won't try to expel it

[jacky]

actually...catnip isnt only a potentiator....it is an opioid active herb!!
"
The essential oils of Nepeta species including Nepeta phyllochlamys P. H. Davis, N. nuda L. ssp. nuda, and N. caesarea Boiss. have been screened by use of the tail-flick and tail immersion (52.5°C) methods. Of the species studied, only N. caesarea showed significant analgesic activity, besides marked sedation, which was also blocked by naloxone, indicating involvement of opioid receptors. Moreover, it was only active on mechanical, not thermal, algesic response which suggests specificity for specific opioid receptor subtypes, excluding μ-opioid receptors. Because 4aα,/α,/aα. -nepetalactone is the main component of the essential oil of N. caesarea, and is present at very high levels (92-95%), it is concluded that 4aα,7α,7aα-nepetalactone is the active principle and has a specific opioid receptor subtype agonistic activity.
"

we have known about the activity of this one for quite awhile.

I talked a friend into smoking a ciggy dipped in catnip oil just to test the essential oil out. he smelled like that fishy smell for a day or two. completely hilarious.

catnip is psychoactive....but not really as a main course.

the potential of catnip as a potentiator, or as a withdrawal aid is an obvious...at least for some temperaments.

catnip is dope!

[GOLD N DIEMONDS]

OKAY I will buy that
Any Idea why IT DOES make cats trippy?
I mean they will trip and run and play with unseen thing to point of physical exhuastion, if you not careful with them?

[EleusisII]

Dude... They get high!

Works on their pheromonc receptors, which cats have more of than humans.

Catnip=cat-coke

[Chemical_Boy]

I smoked a huge, fat dube of the kitty nip when I was a teenager. Found that on the classic document "legal highs" that was all over the old sites like Lycaeum and what not. Didn't do shit to me, but I was suprised at how smooth the smoke was:p

[GOLD N DIEMONDS]

Dude... They get high!

Works on their pheromonc receptors, which cats have more of than humans.

Catnip=cat-coke

DAMN EII HOW IS IT U KNOW SO MUCH?
seriously, have 2 cats and have to treat it like dope/drugs with them
I don't know if at some point their biological instincts
would ah cut them off (pavilalon dogs/cats)
I cut them of cause their me 2 best friends
not willing to take chance on killing me kittens
with catdopenip

:rolleyes:

[EleusisII]

HEY! I DIDN'T GET IT OFF SOME RANDOM WEBSITE, K? I GOT IT FROM WIKIPEDIA!

Don't need to worry about the cats ODing. I used to have an old cat, 20 years old, would barely move the entire day. Except for when I got the catnip out for him. He'd go crazy, jump back and forth, and act like a kitten.

[GOLD N DIEMONDS]

HEY! I DIDN'T GET IT OFF SOME RANDOM WEBSITE, K? I GOT IT FROM WIKIPEDIA!

Don't need to worry about the cats ODing. I used to have an old cat, 20 years old, would barely move the entire day. Except for when I got the catnip out for him. He'd go crazy, jump back and forth, and act like a kitten.

OH A WIKI GUY!
well was that all of your question now, or none of them/
so you say I can smoke this then HUH
:rolleyes:

[limitless_euphoria]

Nobody has asked yet so I will... do you think you could plug catnip? And NO, I'm not going to try. Someone else can do it and get back to us with results.

[OxyQueen]

HEY! I DIDN'T GET IT OFF SOME RANDOM WEBSITE, K? I GOT IT FROM WIKIPEDIA!

Don't need to worry about the cats ODing. I used to have an old cat, 20 years old, would barely move the entire day. Except for when I got the catnip out for him. He'd go crazy, jump back and forth, and act like a kitten.

Kinda like when we are all lying around w/out our dope, you give us a hit/shot/pill..we're up and movin!
I agree though, it definitely is kittie coke.

My daughter JUST got a kitten, i mean little like 7 wks old...what age can u start giving her catnip? I think she's too young yet...anyone know? I know TOTALLY off subject but inquiring minds wanna know:p

[GOLD N DIEMONDS]

Kinda like when we are all lying around w/out our dope, you give us a hit/shot/pill..we're up and movin!
I agree though, it definitely is kittie coke.

My daughter JUST got a kitten, i mean little like 7 wks old...what age can u start giving her catnip? I think she's too young yet...anyone know? I know TOTALLY off subject but inquiring minds wanna know:p

I think I would wait until at least I year old
that is where you kind of switch from kitty to CAT food
kitties act like their on catnip all the time
And not real sure about cat to human years
but wouldn't be giving a 10 year old kid ah -coke
;)

[EleusisII]

^^^^

Word... Wait at least till kitty is a teen-eh-cat. You know, starts developing an attitude, stays out with cat friends at all hours of the night, and writes bad emo poetry!

[GOLD N DIEMONDS]

^^^^

Word... Wait at least till kitty is a teen-eh-cat. You know, starts developing an attitude, stays out with cat friends at all hours of the night, and writes bad emo poetry!

steals your credit cards
get multiple piercing
and a MOhawk
tries to register on OPI
looks for CWE on catnip

and plugging
the usual shit:D

[doctor diesel]

Aaaaa....
HardiHardiHarHar!
Ha! Ha! Haha!

Dat's my teenagers you're describing G'n'D.
And by the way, I think the OT's homo-erotic doctor is talking asswash.


Doc

[Paregoric Kid]

wow thanks for quoting that paper jacky. I never knew it had opioid properties. I've been growing catnip for years, for my cats and my friends cats. actually a few months back a friend of mine was desperate for a buzz of any kind, he isn't very bright, anyways he saw I had a stash of wild catnip and asked if he could smoke some. I smoked a few bowls with him. I think it made us a little tired. the chemical that makes the cats go nuts, nepetalactone, doesn't have the same effect on humans because we lack the receptor to feel its effects. I will have to do some more research. there are many varieties of catnip, there is the traditional strain and a very potent wild strain as well as catmint and lemon catnip. some people use catnip as a tea, it is related to mint and I am trying to cross mint with nip. I've also seen herbal cigarettes that had catnip in them. I've also tried using this herbal pill that had valerian and catnip and a few other herbs, it was for relaxing and to help get to sleep. I did use that as a potentiator and it seemed to add drowsiness. I do know that cats react to opiates much differently than most other animals and I also know for a fact that catnip is very safe for cats and humans. from what I've heard it is more of a stimulant to cats and more of a depressant to humans. in an old herb book I have it mentions that in the 60s people tried using catnip as a legal high. any more info on its opioid effects?

[Papa Verine]

wow thanks for quoting that paper jacky. I never knew it had opioid properties. I've been growing catnip for years, for me and my friends cats. actually a few months back a friend of mine was desperate for a buzz of any kind, he isn't very bright, but he saw I had a stash of wild catnip and asked if he could smoke some. I smoked a few bowls with him. I think it made us a little tired. the chemical that makes the cats go nuts, nepetalactone, doesn't have the same effect on humans because we lack the receptor to feel its effects. I will have to do some more research. there are many varieties of catnip, there is the traditional strain and a very potent wild strain as well as catmint and lemon catnip. any more info on its opioid effects?

Does everybody completely lack this receptor? Is it something that's 100% exclusive to cats and not humans? I'm just curious. And I also wonder what other receptor activity nepetalactone might have. I'm not a big fan of the tail-flick test or similar methods because it doesn't equate to "opiate like effects" in the real world with such common herbs.

You have to figure people have been ingesting this common herb in one way or another for many, many years. We should have a very good idea of which ones work or don't work. Obscure plants from far-off places are a different story. But catnip is almost certainly just going to be catnip.

[Paregoric Kid]

yeah all humans lack these receptors. it is believed that nepetalactone binds to one or more feline olfactory receptors, similar to how pheromones work. approximately 2/3 of cats respond to catnip and other cat attractants like valerian. its interesting that even many of the bigger felines like lions and tigers respond to catnip. so this receptor seems to be limited to most but not all animals in the feline family.
also from that paper it seems to suggest that nepetalactone acts on the delta or kappa opioid receptor. they should do a test using receptor specific antagonists.

[Paregoric Kid]

check these out too, pretty much everything in the Nepeta genus is a type of catnip.
Effect of Nepeta glomerulosa Boiss. Aerial Parts Aqueous Extract
on Morphine Withdrawal Syndrome in Mice
Hossein Hosseinzadeh*, Toktam Ziaee
Department of Pharmacodynamy and Toxicology, Pharmaceutical Research Center, Faculty of
Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
The effect of aqueous extract of Nepata glomerulosa Boiss. aerial parts on
morphine withdrawal syndrome was investigated in mice. Dependence was induced
by subcutaneous injections of morphine for 3 consecutive days. On day 4, morphine
was injected 2 h prior to intraperitoneal injection of naloxone. The number of
jumps during a 20 min. period after naloxone injection was considered as a measure
of the withdrawal syndrome. Open field and rotarod tests were also performed. The
results indicated that the aqueous extract (0.1 to 2.8 g/kg, s.c.) and diazepam (5 mg/kg)
reduced the number of jumps (58±2.3 to 10±0.82, p<0.001 vs normal saline,
87±3.4). The extracts also reduced motion balance and locomotion activity. It is
concluded that the aqueous extract of N. glomerulosa aerial parts could diminish
morphine withdrawal syndrome.
Keywords: Diazepam; Morphine dependence; Nepeta glomerulosa; Withdrawal
syndrome.
Received: May 8, 2005; Accepted: September 2, 2005

Analgesic activity of Nepeta italica l.
Süleyman Aydin 1 *, Tuba Demir 1 3, Yusuf Öztürk 1 3, K. Hüsnü C. Baer 2 3
1Department of Pharmacology, Faculty of Pharmacy, Anadolu University, Eskiehir 26470, Turkey
2Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskiehir 26470, Turkey
3Medicinal and Aromatic Plant and Drug Research Centre (TBAM), Anadolu University, Eskiehir 26470, Turkey

*Correspondence to Süleyman Aydin, Anadolu Universitesi, Eczacilik Fakultesi, Farmakoloji, 26470 Eskisehir, TURKEY

Funded by:
Research Fund of Anadolu University

Keywords
analgesia; Labiatae; Nepeta viscida; Nepeta italica; essential oil; 1,8-cineole; opioid

Abstract
A screening study was performed on/by essential oils of Nepeta viscida Boiss and Nepeta italica L. using tail-flick and tail immersion (52.5°C) methods. N. italica samples were collected from three different*localities of Turkey. Surprisingly, only one of the essential oils showed significant activity, which was blocked by naloxone, indicating the involvement of opioid receptors. This was seen only with the mechanical but not the thermal algesic stimulus, suggesting a specific activity on opioid receptors, excluding mu receptors. The same, active essential oil also exhibited a non-competitive inhibition of acetylcholine contractions of isolated rat ileum but it was inactive on the isolated rat aorta. Furthermore, a correlation between the analgesic activity and the amount of 1,8-cineole was noticed. Ursolic acid plays a role in Nepeta sibthorpii Bentham CNS depressing effects
M. F. Taviano 1, N. Miceli 1, M. T. Monforte 1, O. Tzakou 2, E. M. Galati 1 *
1Pharmaco-Biological Department, School of Pharmacy, University of Messina, Vill. SS. Annunziata, 98168 Messina, Italy
2Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zographou 15771 Athens, Greece
Abstract
The sedative, anticonvulsant and analgesic activity of ursolic acid, a terpenoid bioassay-isolated from Nepeta sibthorpii Bentham, was evaluated in mice. The oral administration of ursolic acid (2.3 mg/kg) produced a significant depressant effect on CNS by reducing spontaneous motor activity and the number and lethality of pentylenetetrazol (PTZ)-induced seizures. Two models of nociception, the writhing test and the hot plate test, were also used to examine the analgesic effect of ursolic acid. At a dose of 2.3 mg/kg, ursolic acid caused an inhibition of acetic acid-induced abdominal constriction, but was inactive in the hot plate test. Treatment at a higher dose (20 mg/kg) significantly increased the reaction time in the hot plate test. This effect, reversed by naloxone, evidently involves opioid receptors, but the analgesic activity of ursolic acid may be related also to the antiinflammatory and antioxidant properties of this compound. Copyright © 2007 John Wiley & Sons, Ltd.
Received: 17 August 2005; Accepted: 4 October 2006

[WhyCatsPaint]

Human uses:

Catnip tends to have a sedative effect on humans. It is most often drunk as a tea.
It is also useful for settling an upset stomach. It has also been used to treat headaches, scarlet fever, coughing, insomnia & smallpox.

Catnip can also be used for cuts, studies show it has a natural healing quality. Crush fresh catnip leaves, damp them & apply to your cut.

Effects in Felines:

The effects of catnip seem to change from cat to cat.

One interesting fact is that when sniffed, catnip will stimulate kitty, however when eaten it will act as a sedative.

When a cat encounters catnip, it usually sniffs it, rubs against it, licks it & finally eats it. It's actually the sniffing that gets produces the high, it's believed that cats eat catnip to bruise the catnip & therefore release more of the nepetalactone. The high produced will usually last between five & ten minutes

Around 50% of cats are affected by catnip, and those who are, are affected to differing degrees. Kittens younger than 8 weeks old aren't able to enjoy it's effects. In fact, they show an aversion to it. The response to catnip appears to be inherited as an autosomal gene. It's not just domesticated cats who enjoy the effects of catnip, many lot of wild species also enjoy it. Cats can smell 1 part in a billion in the air. Males & females, entire or desexed, there appears to be no one group who is more readily affected by catnip than another.

Nepetalactone causes a hallucinogenic effect. Some say the effects are similar to LSD, others say similar to marijuana. Because cats roll on the floor, which mimics a female in estrus, it has been suggested that catnip acts as an aphrodisiac, but this is unlikely as males react in just the same way. What is likely is the cat is reacting to similar "feel good" pheromones released during sexual courtship/activity. However, non sexual behaviour including playing, chasing & hunting can also be observed. The response to catnip is via the olfactory system. Even cats who can't smell will can still respond to catnip.

Catnip is not harmful to your cat. They won't overdose on it. Most cats know when they've had enough & will refuse any further offers.

[OpiXPO]

I've been told by homeopathic(sp?) doctors that catnip is something along the lines of a sleep aid and can be used as such. So it might be possible that you really did get extra high from cat nip.


I definitly do not remember making this post. ^

[chopstix]

I definitly do not remember making this post. ^

I don't remember %90 of what I've posted on this board..

I suspect the pills, but I can't be certain..

[GOLD N DIEMONDS]

I don't remember %90 of what I've posted on this board..

I suspect the pills, but I can't be certain..

I DON'T think you are alone there
we could stop all usage for say 3 month and see
but
naw , it not THAT important;)