IV OC

[ANYPAINKILLER]

Swim has a tolerance of 80mg of OC at one time snorting it.....he wants to be able to take less medicine and still get a good feeling and take awayback and neck pain.....He has Intra muscular before around 20 mg and got no significant effect.....He is ready to IV ....how man mg would swim have to take to IV without OD.....I know it depends ...but a round about answer would be greatly appreciated.. and he has three and a half 20mg OC left

Thanks your help would be greatly apprecitated

[ANYPAINKILLER]

A litlle help PLEASE:D

[aj11]

look in the search section, there is plenty of info in there

[caesee]

Swim has a tolerance of 80mg of OC at one time snorting it.....he wants to be able to take less medicine and still get a good feeling and take awayback and neck pain.....He has Intra muscular before around 20 mg and got no significant effect.....He is ready to IV ....how man mg would swim have to take to IV without OD.....I know it depends ...but a round about answer would be greatly appreciated.. and he has three and a half 20mg OC left

Thanks your help would be greatly apprecitated

come on man, do you ever serch the forums? ALL the posts you have made are question you can answer YOURSELF by SEARCHING...then you seem to get mad when someone points this out to you AGAIN and AGAIN....

[shaunclo]

Swim has a tolerance of 80mg of OC at one time snorting it.....he wants to be able to take less medicine and still get a good feeling and take awayback and neck pain.....He has Intra muscular before around 20 mg and got no significant effect.....He is ready to IV ....how man mg would swim have to take to IV without OD.....I know it depends ...but a round about answer would be greatly appreciated.. and he has three and a half 20mg OC left

Thanks your help would be greatly apprecitated

If you can snort an 80 in one sitting, I would start with 10 mg's for the 1st shot, then 20 mg's. But only after a couple of hours after the 1st shot.

[shaunclo]

whatever you do, DO NOT SHOOT UP SOME, THEN SOME RIGHT AFTER!!

If you shoot 10mg's and its not strong enough, wait a couple of hours then shoot 20 mg's, if thats still too weak than up by 10 millie. I wanted to make sure I covered my bases here. Some people will shoot and think they are not where they want to be, then do a follo-up shot, these are the ones that OD.

[Phluck]

From what I understand, while shooting OC might get you a rush at first, the overall potency won't be THAT much greater than snorting it.

Drugs like heroin and morphine don't absorb very well orally, but when injected their potency increases a lot. Oxycodone, on the other hand, absorbs extremely well orally, so shooting it won't make as much of a difference.

[shaunclo]

From what I understand, while shooting OC might get you a rush at first, the overall potency won't be THAT much greater than snorting it.

Drugs like heroin and morphine don't absorb very well orally, but when injected their potency increases a lot. Oxycodone, on the other hand, absorbs extremely well orally, so shooting it won't make as much of a difference.

Ehhhhh, for me thats just not the case, snorting an OC and banging an OC is much different. Theres just nothing that beats banging, but for OC's the rush seems to go away pretty fast.

[devilsdrug]

NEVERMIND, this is going nowhere i dont believe your in it to kill pain since i remember your first post dude if your in to get high just say so dont go lookin for sympathy since snortin will last longer than ivin

[nikz]

interesting observation
N

[musingpoet]

Snorting is the best route. Lasts longer, etc... But if you must bang, be careful. I can snort 80's but that means nothing tolerance wise if I bang. I take a 80mg Oxy and draw it up in three shots and then take them in two hour intervals. The rush is great, but once that is gone, for me at least, I am as sober as a judge. Waste of money and drug IMHO.:cool:

[exitwound]

from what I've heard, oxy has a low nasal bioavailability.

rectal bioavail. is better but i'm not sure exactly how it compares with oral. it's no major slam dunk, i can now confirm that first-hand although it does come on faster than anything except IV when you plug it.

[chemboy7]

From what I understand, while shooting OC might get you a rush at first, the overall potency won't be THAT much greater than snorting it.

Drugs like heroin and morphine don't absorb very well orally, but when injected their potency increases a lot. Oxycodone, on the other hand, absorbs extremely well orally, so shooting it won't make as much of a difference.

Yeah, but we aren't talking about oral dosing are we? The reason you get that close to immediate buzz from insufflation is because the nasal cavity that you are administering said compound to is rich in mucus membranes full of waiting blood vessels anxious to deliver your gold to your CNS in stellar time... thus faster absorbsion and a closer feeling to that "rush". I would say, IMO, if your are getting satisfactory result from 80 mg insufflated that 25 - 30 mg should put you right where you want to be IV wise. I would advise that before you take that all too familiar dive into IV administration that you give some though to the "browning method" to get yourself accostumed to the differentialites and work your way up from there... better safe that sorry, even if it means sticking a needleless drum into your bum... as coamTOES so eliquently put it. Comparable to an IM injection although, in most cases, peak plasma levels raise faster (due to all the waiting blood vessels (much more so than in the sinus) just craving that illicit substace to carry said substance off to the brain at increased levels... thus making it more efficient.

[goagirl23]

I think IV'ing Oxy is a waste of time and Oxy. I got curious the other night and tried it rectally and was quite amazed. My usual dosage is 90mg. I did 70mg orally and 20mg rectally immediatley after. The effect was much more intense than usual. Infact, It had been quite sometime since I could barely keep my eyes open, or focus them, not to mention itching like crazy. It was a wonderful couple hours!

[shaunclo]

Just goes to show you how much it varies, I can snort 180mg's of oxy without a flicker of my eye, but if I even IV 20 mg's, I feel a pretty strong high. It does last a very short time though. So if snorting is working for ya, I would keep it there.

[exitwound]

Ehhhhh, for me thats just not the case, snorting an OC and banging an OC is much different. Theres just nothing that beats banging, but for OC's the rush seems to go away pretty fast.

That's because of the fast come-on. But in terms of total efficiency with regard to "buzz-hours" instead of just "peak buzz level"......oral is the best way to go. Just take more. It's also much safer for your health, your lungs, your heart, your veins, etc.....for the love of God, don't end up with a horrible chronic health condition like me. Trust me no buzz is worth it.

[shaunclo]

That's because of the fast come-on. But in terms of total efficiency with regard to "buzz-hours" instead of just "peak buzz level"......oral is the best way to go. Just take more. It's also much safer for your health, your lungs, your heart, your veins, etc.....for the love of God, don't end up with a horrible chronic health condition like me. Trust me no buzz is worth it.

I thought you never IV's before EW?

Are you saying you use to, but dont anymore due to some serious problems it caused you??

[DaOxyMan]

Shaunclo, i agree w/ you 100%. i aint tryin to be an ass kisser or nuttin like dat, but thats how it is for me..after years of abusin the shits, i wouldnt think twice bout crushin up a couple 80's and snortin, but if i decided im going the IV route this time, i'd carefully chop that bitch into quarters with my sharpest razor for some nice equivalent doses...don't expect the world if your a banger of some quality dope but it is certainly worth it..im tired of hearing peopl esay "IVing OC is not better than oral because of the bioavailability" yeah well so what its all about tha onset yea..thats the whole point of shooting in the first place...ask a junkie on the street about bioavailability and they be like "huh? banging is instant fool" thats the whole fucking POINT! im ranting sorry. shooting OC = good

[DaOxyMan]

dammit what the hell just happened there wit my posts.. sorry im an idiot

[thbronze]

It must be me,i've been eating-after tagamet of course- im,snorting ms 30's and iv morphine chlorhydrate liquid vials,yet none of that has compared to crushing up 100mg M-eslon and iming-great nod.Tolerance?shitty quality on last deal?don't know.Was hoping the vials 1ml. of morph would be the ultimate,probably stick to percs,hydro,zanys,somas

[candy]

I know that the draw to IV opiates is strong, especially for those who have become tolerant to the drug through other routes of administration and are looking for a new route to get the desired effect.

Because pills contain fillers, they do not dissolve completely in liquid and are not meant for an IV route. These very small particles can get trapped in the small blood vessels in your lungs leading to scarring over time and in many cases death from lung failure. Not to mention that these small particles can lead to a pulmonary embolism which can bring about dealth immediately if not treated ASAP.

And I am not trying to take the wind out of anyone's sails here. But as a nurse working with IV drug users, I have seen the effects all too often and really advise that pills not be injected. And I am not trying to use some scare tactic for anyone new here, just trying to help out and pass along a suggestion!
I have seen an increase in IV use with pills lately and the end result can be for some pretty bad.
Just passing along some info!

[exitwound]

I thought you never IV's before EW?

Are you saying you use to, but dont anymore due to some serious problems it caused you??

I've had IV narcotics administered in hospitals, ERs, doctors offices, in the back of ambulances, and in one case, on battlefield although that was an IM morphine syrette for facial and scalp shrapnel wounds.

I've never self-administered using a needle, although I do use a needleless syringe to plug solutions (usually opium tea) for fast-acting severe breakthrough pain control without digestive nausea.

The story is, I can't use a needle even if I wanted to because the same condition that makes my immune system attack my whole body and cause runaway inflammation which produces severe chronic pain of several types......also attacks any IV site which exists on my body, even for short blood draws at the doctor's office. My body freaks out and I've come close to passing out, just in the past few times I've had to have even the simplest mildest form of injection or blood draw...even though I've handled it perfectly fine countless times in years past before I went Stage 3.

It's a blessing and a curse. I'm not sure what would happen if I were hospitalized and needed high-power pain medication (Fentanyl patches?!) along with other IV medications that they hand out routinely. I'd be a "wicked pissah" of a case. It makes me a poor candidate for any kind of surgical treatment for my condition, not that the surgical options look so great even for the average stage 1/2 sufferer.

[shaunclo]

, on battlefield although that was an IM morphine syrette for facial and scalp shrapnel wounds..

CRAZY!!! what war if you dont mind me asking, I always wondered how many mg's of morphine one of those syrettes contained, do you know??

[ZodiacKiller]

I usually just chew my oxys, actually. I find the trade up of immediacy vs. duration of effects to be worth it. I also feel that the length of effects is worth the 20-45 minute wait for onset. Every time I've insufflated OC I was somewhat disappointed.

I don't IV, but if what you say is true, Shaun, then that sounds like it'd be the best 'bang' for your buck. A lot of folks have said it's a waste, though, so I know there are different opinions out there. I've also read quite a few people say that's it's generally not the greatest idea to shoot pills, period, because of the binders and fillers, as Candy said above. All the more reason for me not to go down that road...


ZK

[exitwound]

CRAZY!!! what war if you dont mind me asking, I always wondered how many mg's of morphine one of those syrettes contained, do you know??

I think they come in multiple sizes. The ones I carried were 15mg IM, which is equal to about 40mg instant release oral morphine.

[TTD]

Oxycodone has a bit of an odd profile pharmacologically, it has a very high AUC orally, meaning it has a high absorbtion, but the Cmax, or plasma peak, is not as high.

IV oxycodone has a high Cmax, but a low AUC. IV oxycodone, by the way, is not a street invention, they do make oxycodone injection but dont use it much.

Inhaled oxycodone probably falls somewhere in between, oxycodone itself is entirely capable of penetrating nasal tissue in large amounts, but with the pill binders its inhaled with not a lot of it gets a chance.

I suspect that inhaled OC in the form its in when crushed, probably has a much lower AUC than pure oxycodone hcl. I bet it has a higher Cmax than oral though.

Typically IV administration bypasses hepatic (liver) metabolism of drugs, meaning it takes a lot longer to get rid of them hence they tend to act longer. This effect may not stay that way over long use though.

I think this is the point where i post my lab proceedure on making USP sterile oxycodone injection out of the OC pills, itll be in a new thread somewhere called "Oxycontin IV solution"