first time with DXM..

[hydro chris]

tomorrow will be my first time trying a little DXM.
first a bit of info...
ill have a fentanyl 50mcg on, ill be my second day with that patch on.
when i wake up in the morning say around 10:00 am. ill probably take between 14 to 21mgs of hydrocodone to get rid of any slight w/d's and for a little boost of energy.....
plus i have 100 mgs of Zoloft and 8mgs of k-pin from the night before floating around in my system.

ok so i have the liquid-gels because that's the only ones i came across with only the dextro as the only active ingratiate.. i plan on to take them about 1 pm.
which would be the best way to take them?
i only want to take enough to get a bit of a buzz or/and euphoria. a low plateau if you know what im saying.(nothing serious heavy).
im 29years old, 5'11 and about 175 lbs.
so my main question is how many mgs should i start and go with?

thanks!

[oxyjon]

I've tried using dxm to pontentiate opiates before. I dont have any real positive results though. Mostly more sedated and it caused my mouth and throat to dry up. I didnt experience any more euphoria from it. Usually, the once in a while I take it, I start with about 120mgs. I think thats 4 gel caps. Any more than that and it makes me too tired and groggy. I hope this helps you find a starting point, and hope you have an enjoyable experience.

[ryan]

DXM used to be my DOC...It's awesome, but have respect for it, unlike me..

300-500 mg for a light body trip and minor visuals, 500-1000mg for more of an out of body experience, and then 1000+ for intense alien abduction trips.

In the peak of my DXM addiction I was doing 2-3 grams per night (very insane intense trips with flashbacks and everything, not recommended for newbs)...also, weed goes GREAT with DXM...makes the visuals and even the entire trip alot more enjoyable...lightens the body load and lessens the nausea...also if you have access to cocaine, it's good to have if you start to experience a bad trip, cause the coke will take you str8 out of the trip and into coke land for a little while in order to get your head straight.

IMHO opiates and dxm do not mix, the dex will overpower the opiate feeling and replace it with an anesthetic cold numb feeling. Opiates do not add to the psychedelic part of the trip either.

Also, It's good that you got the dex-alone gell caps...the coricidins and the like contain that other crap, and in large doses it really does make you feel like shit...I forgot exactly what the different additives are called and what their purpose is, but the bottom line is that they suck.

EDIT:

Woops, I must have missed this when I first read your post. DO NOT, I REPEAT, DO NOT MIX ZOLOFT WITH DXM.
WAIT UNTIL IT IS ALL OUT OF YOUR SYSTEM. TRUST ME ON THIS ONE, DO NOT DO IT.

[EleusisII]

If you want a low plateau experience, I recommend going to erowid.org, and figure out exactly how much you need to get there.

THIS IS IMPORTANT: I believe there might be an interaction between SSRIs and DXM, but I don't remember. You might want to look that up too.

And oh yeah: Have a vomit bucket ready, cause you WILL vomit ;)

Check this out:

http://www.erowid.org/chemicals/dxm/faq/dxm_general_info.shtml

Apparently you can risk getting Seretonin Syndrome (Nasty condition that can kill you) if you take DXM together with an SSRI.

Since you're going for a low-plateau experience you'll probably be safe, but if it's in any way possible, I'd wait until the zoloft is out of´your system. Is Zoloft something you take on a daily basis?

[Hoss]

Indeed, it's a very good idea that you are doing some research prior to ingesting your DXM dose, which essentially goes without saying with any substance you put in your body. As I have previously mentioned in threads' past, my 'First Time', my one and only experience with DXM was when I was slipped a pure DXM 'Green Triangle' pill back in the late 1990's while DJing at a rave, thinking it was an MDMA pill, as a then-trusted source gave it to me, and at the time I thought I was somewhat well versed with the pills flowing around my geographical area.

Took it on an empty stomach, felt nothing until about 2 hours later while watching a bunch of E-Tarded ravers racing around a figure-8 track on mini-tricycles out in the pouring rain (I was DJing the outdoor arena but it was eventually rained out, hence out of the free pills given to me that night I decided to take the nastiest one oh so graciously given to thou art, unbenknownst); DRUNK - that's how I felt, then it all went downhill from there. I couldn't move, was running fever and literally steaming out in the cold Oakland rain on a wet and sloppy February night, leaned up on a chain linked fence, unable to see and barely able to speak. A "Bad Scene" as my Pops would put it.

I was eventually able to walk and get the hell out of there - having a trusted friend carry my record box - however I was askew for a few days and the word 'Disassociation' is an understatement of my experience. But, again, this was not planned, and I definitely took WAY too much - a risk when dealing with pills as such.

Not to scare you off, but since this was definitely not a DXM experiment I intended on, I have to admit that I have been extremely weary of this substance ever since, however I have a large amount of friends that have had great experiences with it (when they intended to take it!) and some that even got so far as taking it nearly every day.

In the end, do your research, be safe - especially concerning mixing the SSRI (Zoloft) with DXM - and I'm curious to hear of your experience. I always think of sometime reevaluating DXM, but under completely different circumstances than my previous mindfuck disaster.

[hydro chris]

ok guys thank for the reply's..
iv done a bit of research on the subject. i think ill hold off for another week or two now.
i dont know of anybody that has had experience with it. its like none existence on the upper east coast were im at.
iv read about zoloft and dxm and serotonin syndrome (which i personally know its no fun) happens to me when i take ultram longer than a weeks time period. any more info. is appreciated and thanks again.

[cactus31]

I used to do the DXM thing...it can be pretty intense. Here's a good place to research if you haven't already found it by Google:


http://www.dextroverse.org/


That site should answer any possible question you could have. Lots and lots of reading there!

[EleusisII]

Don't remember the halflife of Zoloft (Could be up to a week) but if it was me, I'd completely quit the SSRI, wait a couple of weeks, and then go for it.

Sure, you're probably not going to get Seretonin Syndrome from a small dose of DXM, but why take the chance?

And that, was my post number 2000!

[hydro chris]

I used to do the DXM thing...it can be pretty intense. Here's a good place to research if you haven't already found it by Google:


http://www.dextroverse.org/


That site should answer any possible question you could have. Lots and lots of reading there!

cool..
thanks for the link

Don't remember the halflife of Zoloft (Could be up to a week) but if it was me, I'd completely quit the SSRI, wait a couple of weeks, and then go for it.

Sure, you're probably not going to get Seretonin Syndrome from a small dose of DXM, but why take the chance?

And that, was my post number 2000!

i differentially cant stop the zoloft for that long..3 day and ill start going into withdrawal.
but yeah, i dont think around 100-115 mgs of dxm, just for a single day will do much harm.but im not sure.

edit..congrats and thank for your 2000th post:cool:

[Hoss]

I differentially cant stop the Zoloft for that long..3 day and I'll start going into withdrawal.

Yes indeed; you know, I have a few Opiated friends who know the realm of Opiate withdrawal, however they almost laugh me off when I speak to them about SSRI withdrawal, which actually does exist and albeit it is different in nature than Opiate WD, it does occur upon abrupt cessation of the intake of an SSRI.

In my personal case, after being prescribed Escitalopram (Lexapro) @ 10mg's per day and taking it every single day for a little over a year, I decided one day to completely stop and 'jump' from my daily 10mg dose; wrong move. At that point of my life, which was around the end of 2006, I definitely already had gone through a few real nice Opiate WD sessions (see : Methadone CT, Morphine CT, etc.) and knew what that was like, but I did not expect any sort of repercussions from quitting my SSRI. My reasoning for quitting Lexapro? Well, for beginners, I gained almost 100 pounds in a year, I felt like a "Diet" version of my old self (loss in interest and "passion" for things; kinda hard to explain), and just an overall dislike of the eventual results I was getting, seeing as how the negative aspects of the situation were definitely outweighing the positive in my mind at that point in time.

So, anyways, when I quit it took but a couple of days for the effects to come about : essentially, it was a week of extreme vertigo, loss of balance, dizziness, lack of energy, lack of appetite complete with an overall mental haze that was hard to shake. After about a week of lying around and watching enough TV to last me a decade, it was gone, and although not nearly as horrifying and drastic as say CT Methadone WD, it definitely was a shitty time that I would not want to go through again. I've heard other Anti-Depressants such as Paxil & Effexor are much worse to come off of.

Eventually I leveled out and actually began loosing weight quite quickly, and lost more than I gained. I am now the only member in my family that is not on an SSRI, thus I have warned each of them to taper if/when they ever want to stop.

[MrCharlesIV]

I've been taking Prozac [fluoxetine] for about 3 years and I've tried to get off of it. I made it five days and had never felt worse before in my life! The only reason I still take it is because my insurance pays for it and I don't want to have to go through SSRI withdrawal hell.

As for the DXM, I've taken half a box of the Coricidin and just felt sick..

[EleusisII]

Wababawhaa?!?

SSRI withdrawal? Interesting. Heard of WDs from Effexor, but this? I'm really curious cause I've never met anybody who had WDs from a regular SSRI like Zoloft or Prozac!

Never experienced it myself, and I've quit them plenty of times.

Just goes to show how little of the brain we really understand.

What does it feel like?

[hydro chris]

Wababawhaa?!?

SSRI withdrawal? Interesting. Heard of WDs from Effexor, but this? I'm really curious cause I've never met anybody who had WDs from a regular SSRI like Zoloft or Prozac!

Never experienced it myself, and I've quit them plenty of times.

Just goes to show how little of the brain we really understand.

What does it feel like?


hoss pretty much just summed it up.
iv been on ssri for 12 year now and zoloft beaning the longest for 7...going from 150mgs ed. to 100mgs ed. sucked ass.
and those doctors back them said.... there not addicting....but i believe this can vary from person to person and the.. time, dosage and length of time of use, my sister starts and stops as she feels she needs to.

"QUOTE FROM HOSS"

So, anyways, when I quit it took but a couple of days for the effects to come about : essentially, it was a week of extreme vertigo, loss of balance, dizziness, lack of energy, lack of appetite complete with an overall mental haze that was hard to shake. After about a week of lying around and watching enough TV to last me a decade, it was gone, and although not nearly as horrifying and drastic as say CT Methadone WD, it definitely was a shitty time that I would not want to go through again. I've heard other Anti-Depressants such as Paxil & Effexor are much worse to come off of.

[MrCharlesIV]

So, anyways, when I quit it took but a couple of days for the effects to come about : essentially, it was a week of extreme vertigo, loss of balance, dizziness, lack of energy, lack of appetite complete with an overall mental haze that was hard to shake. After about a week of lying around and watching enough TV to last me a decade, it was gone, and although not nearly as horrifying and drastic as say CT Methadone WD, it definitely was a shitty time that I would not want to go through again. I've heard other Anti-Depressants such as Paxil & Effexor are much worse to come off of.


^^^That's why.^^^

[hydro chris]

^^^That's why.^^^
dont quite understand what you getting at? sorry.

[MrCharlesIV]

Damn... I posted that not seeing you you had replied to Elesus' post. Sorry.

[Ickyuck]

Is there some Serotonin Syndrome risk that I am unaware of??

I've been DMX'ng for the past week with no problems. I take an SNRI and 2 other antidepressants.

[hydro chris]

[quote=Ickyuck;365930]Is there some Serotonin Syndrome risk that I am unaware of?? quote]

for what iv read yes.. there might be.i thinking it would depend on the med or meds, and the person im guessing.

edit..how much dxm have you been taking and in what form?..and if you dont mind me asking what is your daily intake of substances?

[Ickyuck]

Heh, I posted that thinking someone would answer "Read the post!!"

OK, so I checked, and I take a SNRI, a triazolopyrine derivative, and an atypical antipsychotic (this is all for MDD). I'll be extra careful with my dxm intake.

[hydro chris]

Heh, I posted that thinking someone would answer "Read the post!!"

OK, so I checked, and I take a SNRI, a triazolopyrine derivative, and an atypical antipsychotic (this is all for MDD). I'll be extra careful with my dxm intake.
oh ok!
then do some research!

[EleusisII]

Heh, I posted that thinking someone would answer "Read the post!!"

OK, so I checked, and I take a SNRI, a triazolopyrine derivative, and an atypical antipsychotic (this is all for MDD). I'll be extra careful with my dxm intake.

Yeah, SNRI act on the seretonin system too, so best be careful.
I've had it, well sorta. Wasn't in the hospital or anything, but I was taking too much tramadol along with an SSRI, and it felt pretty fucking creepy (Once the initial mania subsided)

My point is, you'll know when you had too much, trust me!

What's MDD? Manic Depressive Disorder?

[Ickyuck]

Yeah, SNRI act on the seretonin system too, so best be careful.
I've had it, well sorta. Wasn't in the hospital or anything, but I was taking too much tramadol along with an SSRI, and it felt pretty fucking creepy (Once the initial mania subsided)

My point is, you'll know when you had too much, trust me!

What's MDD? Manic Depressive Disorder?

Major Depressive Disorder.
How much tram didja take?? I've been up to 1200 mgs. As for DXM, I decided that I don't like the trippy feeling, so I'm only taking 100-150 mgs at the most. I'm mostly interested in tolerance lowering with that.

[EleusisII]

HOLY FUCKING CRAP!!!

1200 mgs?!?

Geez, the seizure threshold (when you start getting a serious risk of seizures) is 3-400 mg.

You're a hero.

I took 350-400mg I think. On top of 30mg citalopram.
Just goes to show how individually we all react to drugs. With your dose, I'd be in the hospital for sure. The doc shaking his head, mumbling: "Damn drugs and damn seretonin-syndrome. So young and ain't a thing we can do about...."

[Seedy]

^^ I got SS on that same combo. Or possibly 40mg citalopram, can't remember but god damn it scared the living crap out of me! I had to keep walking in circles trying to stop my head from exploding. Not nice!

[EleusisII]

Same dosage of tramadol as me? Crazy and very unpleasant shit, eh?

[Ickyuck]

Same dosage of tramadol as me? Crazy and very unpleasant shit, eh?

Hmm, it was unpleasant yes, butmanageable. My wrists kept twitching, my eyeballs felt like they were peeled open, and my mind was fucking racing. Then again, at that time I developed a huge tolerance.

[resorcinol]

I overdid it with tramadol a few times because it had an interestingly pleasant synergy with pods. In hindsight it was a bad idea. I took 1000 mg over the course of a day a few times, and one of those times I felt very twitchy and strange (that's when I stopped with the tramadol totally). I was putting myself in danger of seizing for no good reason - I should have just increased my pod dose to get higher (although the tramadol + opium combo is unique, admittedly). That's definitely one of the several dumb things I've done with drugs tarnishing my usual perogative to reduce the harm. Every rose has its thorn, I suppose it does.

SSRIs + DXM is not a good idea. Make sure that SSRI or SNRI is like five half lives out of your system before you dex. Even if you don't get SS (many do dex on SSRIs even though it's unwise and don't get SS -- but you CAN -- they're taking a risk there) the DXM high is reportedly made unpleasant by SSRIs due to the excessive blockage of SERT by the two drugs and enzyme inhibition stuff going on.

I made an error once by assuming wellbutrin (DNRI, but not euphoric because it inhibits dopamine release at the same time that it blocks DAT re-uptake) would not interact with DXM. I forgot that wellbutrin (bupropion), while not and SSRI and not an SS risk with DXM -- bupropion is a powerful inhibitor of CYP2D6. This caused me to feel FUCKED not in a good way on 100 measly milligrams of DXM for 36 FUCKING HOURS!!! I'm not kidding! I could tell my body was struggling to metabolize the drug, hence the manifestation of toxicity as nausea and vertigo, etc. It also changed the DXM:DXO ratio so less DXO was circulating than normal -- you DON'T want that. IME, DXM is ONLY FUN if the ratio of DXM:DXO produced by normal functioning levels of CYP2D6 is LEFT ALONE ... messing with it changes the nature of the high, but not in a good way! Holy hell that was one of the worst drug experiences of my life ... I felt so fucked up in an awful way for a LONG time on 100 mg. I know the wellbutrin was the cause too, because when I discontinued wellbutrin b/c it actually made my mental disorders worse, the DXM trips returned to normal. RUN from that combo too, just as you would from the combo with SSRIs. That means NO CIMETIDINE either (since it inhibits CYP2D6 strongly and IME you just don't wanna mess with DXM's metabolism or it won't be fun; it's not like with opioids where they're all mu agonists and we want em all to stick around longer, and the metabolite ratios don't matter.. with DXM the ratios do matter). It's probably OK to have a low concentration of another CYP2D6 substrate in your system like many opioids are, but stay away from the inhibitors of that enzyme when playing w/ DXM!

[Ickyuck]

resorc: Holy shit smarty, I had no idea about the bupropion was such an inhibitor. 36 effing hours???? Also, I am currently on dxm (low dosage, and too lazy to do the math) but it isn't unpleasant. I bet if I took twice much it wouldn't be fun, though. I don't seem to experience the 'warmth' I keep reading about. Is this caused by the SNRI? I have a feeling that waiting five half lives will cause me to get withdrawel symptoms from the SNRI. You know... the infamous "Effexor Head Zaps"...

[Seedy]

Same dosage of tramadol as me? Crazy and very unpleasant shit, eh?

I had some european liquid tramadol, 50mg/ml i think and i'm pretty sure i had around 350-400mg over a couple of hours. Yes, very crazy and full on bad trip intensity unpleasant. And when I say bad trip I mean thinking you're either dead, crazy fucked for the rest of your life or in hell already bad, for those who think they've experienced a bad trip when in fact they just got a bit freaked out. Seratonin syndrome isn't nice.

[Ickyuck]

Well shit. I must of been >THIS< close to suffering from SE. Scary thought... and something I won't risk again. Yikes.