Demerol... Worth going for?

[EleusisII]

Opio-fairy told me that there are Demerol, in plentyful amounts, to be had at the local pharmacy...
Guess it's more common in the US than here, cause I never tried it... So should I invest in some 25mg pills? They're also available in 100mg suppositories.

From what I gather, it's better IV, but how does it compare PO with morphine or oxys?

[PercoDan]

i found a dosing converter online:
http://www.globalrph.com/narcotic.cgi

meperidine 25mg PO = oxycodone 1.67mg PO = morphine 2.5mg PO

seems about right. i think it's safe to say that most people prefer oxycodone over meperidine. interestingly, meperidine is the only opiate that dilates the pupils. a lot of ER docs are thrown off by this when encountering meperidine ODs.

note the disclaimer on website:

Please review the importance of correcting for incomplete cross-tolerance. Equianalagesic conversions should not be considered a simple straightforward calculation. Significant 'inter/intra' patient variability exists depending on the selected opiate, dosage level, and expected response

[edhorfin]

I used demerol orally, IM (hospital admission) and IV. IV is just ok....not very rushy....to be honest, deep IM was my favorite method. Its the ONLY drug I ever would say that about, so far.

[skabbo]

I used demerol orally, IM (hospital admission) and IV. IV is just ok....not very rushy....to be honest, deep IM was my favorite method. Its the ONLY drug I ever would say that about, so far.

+1

IM Demerol is preferable over any other ROA by far. I was in the hospital for collapsed lungs in 2004, and from the minute the put my chest tube in, to the minute they discharged me (2 weeks), they gave me 75-100mg of IM Demerol every 3 hours on the dot (even in the middle of the night, I'd wake up and buzz them for it). Halfway through the first week, they switched me to a patient-controlled IV morphine drip, and after about 4 hours, I asked them to take it out so that I could go back to the Demerol shots.. Both euphoria and analgesia were vastly better with the Demerol.

However, since then I've taken it in pill form, and it kinda sucks orally. Probably didn't take enough (75mg oral)

[PiLL CLiNToN]

dems are nice just make sure they arent "darvocets" which are red and say lilly 100 they SUCK! and are alot of the time confused with the demerols as stupid as that sounds swims had over like 5 or 6 pepole say dems are darvocets sooo yeah be careful i;ve always seen them 2 confused...itd take swim like 3 25mg dems to equal like say 70mg=oc maybe 3 dems =60mg in moprh terms....of course there is always the conparison chart too..that always helped me in dosing terms....but demerol is very good for pain too alot of pepole love the stuff others just hate it.....but hey best of luck hope I've been sum sort of help!

[ryan]

Opio-fairy told me that there are Demerol, in plentyful amounts, to be had at the local pharmacy...
Guess it's more common in the US than here, cause I never tried it... So should I invest in some 25mg pills? They're also available in 100mg suppositories.

From what I gather, it's better IV, but how does it compare PO with morphine or oxys?

What local pharmacy would that be? :P
Are you talking about a "street pharmacy" or is meperedine actually legal there?

[EleusisII]

Whatever local pharmacy I decide to call and leave my order with ;)

Hmm... The 25mg ones don't seem like the best option with my tolerance, I know it comes in 50mg pr ml, 10 ml. bottles for injection though.

I guess my best option would be to get those, and a nurse with a knack for IV?

Hey, don't we have a nurse on call in the Harm-reduction section?!

@Ryan
Believe it or not, the only opie you can get from the "streetpharmacy" here, except morphine if you're SUPER lucky is Ketobemidon. AFAIK it's pretty unknown in the US, no?

[bronyraur]

I'd pass on the Demerol E2–it's vastly overrated in my opinion.

Not to mention the nasty metabolites...

[EleusisII]

Prob good advice Brony. At least until I start dating a nurse or something like that.
You got any experience with Ketobemidon? It seems that it's only used in Scandinavia.

[Poppylvr]

+1

IM Demerol is preferable over any other ROA by far. SNIP Both euphoria and analgesia were vastly better with the Demerol.

However, since then I've taken it in pill form, and it kinda sucks orally. Probably didn't take enough (75mg oral)
Here's another example of diverse reactions to drugs: I was given 150 mg IM following childbirth. Did NOTHING, and I asked them to change the med. They changed the med to 1 percocet which took care of my pain just fine with a little buzz thrown in (this was before my junky days).
Fast forward to when I was shooting up anything I could get my hands on. I injected an entire pain pump syringe of demerol - 20cc=200mg. Nothing, not even a mild little buzz, I apparently lack the correct receptors for demerol and it doesn't do ANYTHING for me - no pain relief & NO BUZZ, even at large doses.

[skabbo]

Here's another example of diverse reactions to drugs: I was given 150 mg IM following childbirth. Did NOTHING, and I asked them to change the med. They changed the med to 1 percocet which took care of my pain just fine with a little buzz thrown in (this was before my junky days).
Fast forward to when I was shooting up anything I could get my hands on. I injected an entire pain pump syringe of demerol - 20cc=200mg. Nothing, not even a mild little buzz, I apparently lack the correct receptors for demerol and it doesn't do ANYTHING for me - no pain relief & NO BUZZ, even at large doses.

Wow, vastly divergent reactions indeed. I have heard from other people that it doesn't do much for them either - it seems to be far less universal in it's effects than most opioids.

I will say however, Brony has a good point with the metabolites.. There is a limit to how long you should keep taking Demerol because of toxic metabolite that accumulate faster than they are eliminated by your body. It is one of the few opioids that has this problem (I believe propoxyphene is another).
By the end of the 2 weeks I was on it (which I subsequently learned is longer than one should take it continuously), I was having some weird psychological side effects that I've never gotten from any other painkiller. I would forget where I was occasionally, and when the nurse removed the IV from the back of my hand, she pulled the rubber tube out, and I absolutely panicked because I was convinced that she left the needle itself in my vein, and that it was going to float around and eventually stab a hole in my heart.. In any normal circumstance, I would've known this was ridiculous, but the Demerol caused me to be a bit delirious and disoriented..

Also, needless to say it shot my tolerance up quite a bit. When they discharged me, I went from 600mg of IM Demerol per day, to the ONE 5mg Percocet daily that they sent me home with. That was a brutal week that followed..

So it may or may not work for you, but even if it does, be safe: don't take it for too long.

[bronyraur]

Prob good advice Brony. At least until I start dating a nurse or something like that.
You got any experience with Ketobemidon? It seems that it's only used in Scandinavia.

No experience with Ketobemidom–it is not prescribed in the US. I've heard that it has great euphoria–and I've also heard some reports that it is much more addictive than other similar opiates, although that opinion is disputed.

[Narkotikon]

Personally, I liked Demerol the two times I did it. But, that was back in college before I was physically addicted, so my tolerance was like 20-30mg of hydro. Very very small to non-existent, so that's probably why. I had the 50mg pills, which were these tiny white pills that looked like a barrel, but cut in half. Sort of like white stumpy things. Anyway, they worked just fine.

The oral bio would be similar to morphine in that it sucks orally if you have any kind of tolerance. I'd suggest getting a higher mg pill (like the 50's, and I think here they even make a 100mg pill, but don't quote me on that) and IV / IM them.

Don't do too much, or for extended periods, because meperidine / pethedine / Demerol does produce toxic metabolites at higher doses and for extended periods of time.

[StackBundles]

I have had access to Dem before in the form of the 50mg pills. I fired them down the few times that I had them and I wasn't too impressed. Demerol has a weird buzz if you ask me. It has that harsh or dirty aspect that Tramadol seems to have. I'm pretty sure that I developed a ferocious headache after a couple of days of repeated use which might have something to do with the metabolites that a few other posters mentioned.

Oops...I noticed that you were asking about oral usage and not the other route.