method of administration, girls? [Archive]

View Full Version : method of administration, girls?

Angelwolf13

01-02-2009, 09:55 AM

candy

01-02-2009, 11:57 AM

To be honest as a health professional here, I have never used that route of administration before,
but if you do a search on the site, you should finds ton of forums and threads meant to help with this.
But, anything else and I can help you!

I have heard that many enjoy it!
Any other ladies want to ring in here?

Poppylvr

01-02-2009, 12:03 PM

i am so happy this is moderated by a health professional!

i was wondering about something... i heard that plugging was like the next best thing to iv. the only problem i have with that was the bad memories i have the last time i was in icu... every four hours for a week some nurse was sticking something up my ass. i don't recall it fondly.

i was thinking, i have this extra orifice. i mean, if i had to, isn't there like a way i could use it? would it be effective at all? i was thinking i could have more fun with that than plugging. i'm just curious, you know....

be back on later, i can never get more than 4 hours of sleep at a time. TIA
Well, Angelwolf, like Candy, I have never tried the Tunnel Of Love approach. I'm curious now what Suboxone would do in there, as it's all mucus membranes. (AW - I'm a suboxone only kinda gal these days).
I propose some of we girlies try out the Cleft of Passion & report on our results!

sweet pea

01-02-2009, 01:29 PM

omg! i never thought about that before.

hmmmmm, i'm planning on taking another 1/2 suboxone in an hour or so. maybe i'll give it a whirl. ha. probably not. i'm trying to get some ass tonight. can you imagine hubby going "down there" and tasting suboxone! lmao. uhhh, lemme try to explain that one!

i'm so excited to hear how this works out.

Method

01-02-2009, 01:36 PM

Cant remember where i heard or read about underage girls soaking hygine products in vodka and then incerting it .... and the only thing i could think of was "why?"

Angelwolf13

01-02-2009, 04:16 PM

thanks for your responses! i'm kinda itching to try it now. especially with the sublingual stuff!

Princess

01-02-2009, 05:25 PM

^^^
Do try and let us know how it goes :p

Hiram

01-02-2009, 07:06 PM

Don't be doing anything to fuck up the pH is such a sensitive area ladies. Sheesh.

losangeleslifer

01-02-2009, 07:10 PM

:D........

ka11ink

01-02-2009, 07:10 PM

That's one way to get ur main to go south, stuff it full of high oral bioavailability pharmaceutical dope, he'll go down unda.

Princess

01-02-2009, 07:23 PM

I don't stick anything where the sun don't shine. That's why I suggested she try it and let us know :p

Don't be doing anything to fuck up the pH is such a sensitive area ladies. Sheesh.

That does nothing for me. No need for me to "coax" anyone to "go south". *yawn* boring *

That's one way to get ur main to go south, stuff it full of high oral bioavailability pharmaceutical dope, he'll go down unda.

Hiram

01-02-2009, 07:27 PM

That's one way to get ur main to go south, stuff it full of high oral bioavailability pharmaceutical dope, he'll go down unda.

Some of us don't have to be coerced, unless there's a problem, then all the pharmaceutical dope in the world wouldn't work.

Method

01-02-2009, 07:33 PM

Some of us don't have to be coerced, unless there's a problem, then all the pharmaceutical dope in the world wouldn't work.

I will second that ..... +1

chopstix

01-02-2009, 07:45 PM

+2

Method: Just curious, is that mis-spell in your sig intentional?? I could see how it could have meaning as it is, but my inner grammar nazi flips out everytime I see it..

Oh and I fully agree w/ Hiram and Princess - leave the kitty alone, if ya gotta plug something, just plug it in yer butt.

Hiram

01-02-2009, 08:42 PM

I mean if that's big of a deal and you want to have fun plugging, maybe just rub yur clit while you have the turkey baster doing its thing.

Pandora

01-02-2009, 08:53 PM

I mean if that's big of a deal and you want to have fun plugging, maybe just rub yur clit while you have the turkey baster doing its thing.

LMAO!

IDK if I could ever personally try it, but I'm actually extremely interested to know if it does work.

It could be the new sexual craze, guys lubing up their dicks with fent and fucking girls into euphoria.

WV_Girl_26

01-02-2009, 09:03 PM

Actually my pelvic pain specialist INSTRUCTS me to insert my Valium vaginally. One of my med conditions, well a few of them, cause sex to be very painful. Inserting vaginally as opposed to taking it orally makes a huge difference. I take 30mg inserted vaginally prior to sex. My Valium bottle actually say "Insert crushed tablets vaginally 30 minutes prior to intercourse" no shit. I can tell a difference as opposed to taking it by mouth but can't compare it to plugging as I have never done it. It really relaxes the muscles, I have pelvic floor dysfunction and it is so tight nothing is going in there without a chemical relaxer;), TMI sorry. Kinda kills the spontaneity of it all "sorry hon, grab my Valium, some jelly, the crusher and gimme 45 minutes and I'll be right with ya" . Hubby takes it in stride tho. Jokes with me and says"not only do you have to get all fucked up to have sex with me your pussy does too" lol such a joker!

Hiram

01-02-2009, 09:04 PM

LMAO!

IDK if I could ever personally try it, but I'm actually extremely interested to know if it does work.

It could be the new sexual craze, guys lubing up their dicks with fent and fucking girls into euphoria.

Now suddenly I don't care about pH and it all makes sense. I was thinking about it all wrong. Just gotta smack me every so often to wake me up.

Pandora

01-02-2009, 09:10 PM

Now suddenly I don't care about pH and it all makes sense. I was thinking about it all wrong. Just gotta smack me every so often to wake me up.

LOL!

Glad I could make you see the other side of things, man. :p

norseman

01-02-2009, 09:23 PM

LMAO!

IDK if I could ever personally try it, but I'm actually extremely interested to know if it does work.

It could be the new sexual craze, guys lubing up their dicks with fent and fucking girls into euphoria.

Wow, Dirty Dreams tonight :jerkoff: Thanks Pandora.

chopstix

01-02-2009, 09:30 PM

I've heard of intercourse with cocaine on teh weener..

Coke and sex don't mix at all for me though..

EleusisII

01-02-2009, 10:23 PM

Oh lord no, not coke... You could set your dick on fucking fire, and you wouldn't notice it with the coke anastethisizing it. No thanks, I'd rather feel if I'm doing some damage...

LOL!
Glad I could make you see the other side of things, man. :p

Actually, ehm, I believe that ROA is called intravaginal, and yeah it does work. Fent, oxy, coke...
Of course you have to be a class A pervert to even consider to this. And what did some poor pill do, to deserve ending up on my dick anyways...

losangeleslifer

01-03-2009, 12:29 AM

Now this, is a good thread. If the guys would stop posting!

underide

01-03-2009, 01:02 AM

I've heard of intercourse with cocaine on teh weener..

Coke and sex don't mix at all for me though..

I've read an article where some guy actually murdered his own wife with a massive cocaine overdose by means of using something like a 5ml syringe loaded with coke to insert it into his already incapacitated/sedated wife's vagina

He thought he could get away with it by making it look like a coke OD and the Autopsy showed a massive coke OD

The guy was convicted of murder though

but the main point, to the OP, if the coke was sufficient to kill that lady in that case, then maybe the ROA you're thinking about would be good to use

Just be careful with the amount you use, i guess

sunsrequiem

01-03-2009, 01:25 AM

I like to do research before posting...I hate sounded like an idiot unless i'm drunk, because then it's just fun...but I found this sweet chart:

Buprenorphine bioavailabilities:

intravenous: 98%-100%

intranasal: 50%
"Studies of buprenorphine bioavailability have also examined the [...] intranasal (bioavailability, 48%)
"The bioavailability of buprenorphine, HCl (BPP) in sheep after nasal administration of two formulations has been studied. 0.9 mg BPP in 150 microl was administered nasally and compared to 0.6 mg i.v. The test solutions were formulated with 30% polyethylene glycol 300 (PEG 300) and 5% dextrose, respectively. The bioavailability for PEG 300 was 70% (S.D.+/-27%, n=6), whereas the bioavailability for 5% dextrose was 89% (S.D.+/-23%, n=6)."
"Mean intranasal bioavailability was 48.2 +/- 8.35% (mean +/- s.e.m.) of the intravenous value"

intramuscular: 68%
"The observed mean intramuscular bioavailability was 68%"
"Studies of buprenorphine bioavailability have also examined the intramuscular (bioavailability, 50%–100%)"

intrarectal: 54%
"bioavailability of the drug was found to be: [... ]intrarectal (54%)..."
"Relative to the 100% bioavailability from the intraarterial route the mean bioavailabilities were [...] intrarectal, 54%..."

sublingual: ~30%
"Buprenorphine is well absorbed sublingually, with 60% to 70% of the bioavailability of intravenous doses"
"Study results indicate that bioavailability of sublingual buprenorphine is approximately 30%"
"Literature on bioavailability of sublingual buprenorphine presents variable numbers ranging from. 19–58% of the administered dose."
"Relative to the 100% bioavailability from the intraarterial route the mean bioavailabilities were [...] sublingual, 13%"

oral: 10%
"the oral bioavailability for buprenorphine is state to be 10%"
"due to extensive first-pass metabolism, buprenorphine has very poor oral bioavailability (10% of the intravenous route) if swallowed"

intrahepatoportal: 49%

intraduodenal: 9.7%

I've never plugged anything, but make sure your colon is clear before you do...same as if you were doing anything back there. Your feces will absorb the drug and you won't feel as good as you should...i mean as good as you can feel after inserting something in your anus if you're not use to it. haha

Princess

01-03-2009, 01:45 AM

O.M.G.

Earlier I posted in another thread that sex was the last thing on my mind these days.

On second thought, I'll take a fent dick ANY DAY!!

LMAO!

IDK if I could ever personally try it, but I'm actually extremely interested to know if it does work.

It could be the new sexual craze, guys lubing up their dicks with fent and fucking girls into euphoria.

Angelwolf13

01-03-2009, 01:58 AM

I'll take a fent dick ANY DAY!!

you took the words right out of my mouth! is there a case study? i'd like to volunteer!

"fucking girls into euphoria", i love it! pandora, you're a genius!!!!!!!

p.s. i haven't tried it yet. still waiting for mr. fent to come along.

Princess

01-03-2009, 01:59 AM

I'm getting out my little black book now....
;)

you took the words right out of my mouth! is there a case study? i'd like to volunteer!

"fucking girls into euphoria", i love it! pandora, you're a genius!!!!!!!

p.s. i haven't tried it yet. still waiting for mr. fent to come along.

chopstix

01-03-2009, 02:03 AM

Comment withheld :)

poonwhalla

01-03-2009, 02:08 AM

I now would like to vote myself as the fent dick administrator. Please send pics of administering site to me for consideration to participate in this study.

In2TheWoods

01-03-2009, 03:00 AM

This is a fascinating topic. Actually, I read an experience report on erowid once that dealt with this very thing. A group of women friends would get together and experiment with psychoactives every few months. One of these get togethers (way better than a book club or tupperware party) was dedicated to vaginal administration. They tried a variety of drugs but I think it said the best results were derived from benzos. I thought that made sense since there are sublingual preparations of many benzos.

This made me think that the matrix type fent patches would work really well since they are great for sublingual administration. Although, I guess since they're preferred sublingually over the gel because it's difficult not to swallow the gel (I feel like there's a dirty joke in there somewhere), that wouldn't be an issue with this roa. So either patch would likely work. Somebody has got to woman-up and try it first (and then admit to it) for the advancement of science. If it's awesome we'll have a retort when men brag about peeing standing up.

Angelwolf13

01-03-2009, 03:17 AM

Somebody has got to woman-up and try it first (and then admit to it) for the advancement of science.

admit to it??? fuck, i'd brag about it!!!! where the hell do i sign up????? ;) i LOVE science!

EleusisII

01-03-2009, 03:55 AM

If it's awesome we'll have a retort when men brag about peeing standing up.

LOL! Back to the drawing board, sorry...

Man: "I can pee while standing up!"
Woman: "So can I, but it gets kinda messy... On the other hand, I can cram pills up my pussy!"
Man: "Whaaaa?"

In2TheWoods

01-03-2009, 06:23 AM

LOL! Back to the drawing board, sorry...
Man: "I can pee while standing up!"
Woman: "So can I, but it gets kinda messy... On the other hand, I can cram pills up my pussy!"
Man: "Whaaaa?"

Fair enough. Maybe men wouldn't concede that a woman being able to take drugs through her lady business trumps upright precision peeing. But multiple orgasms are hard to argue with.

Princess

01-03-2009, 06:51 AM

You should make a thread for this in the buprenophrine section...if it's not already there. Very interesting.

Where'd you find it?

Sucks it doesn't include the newly discussed ROA... "inserting in the vagina" ha ha ha

I like to do research before posting...I hate sounded like an idiot unless i'm drunk, because then it's just fun...but I found this sweet chart:

[B][U]Buprenorphine bioavailabilities:

*snip*

I've never plugged anything, but make sure your colon is clear before you do...same as if you were doing anything back there. Your feces will absorb the drug and you won't feel as good as you should...i mean as good as you can feel after inserting something in your anus if you're not use to it. haha

EleusisII

01-03-2009, 07:55 AM

Fair enough. Maybe men wouldn't concede that a woman being able to take drugs through her lady business trumps upright precision peeing. But multiple orgasms are hard to argue with.

So is the abominable snowman, the Loch Ness monster, and other mythical creatures that we all heard about, but oddly enough never see:p

blutuesday

01-03-2009, 10:02 AM

Yes, u can use vaginal as a ROA on certain meds. I know a few patients that had to administer certain meds this way

candy

01-03-2009, 01:06 PM

Angelwolf13

01-03-2009, 01:21 PM

So is the abominable snowman, the Loch Ness monster, and other mythical creatures that we all heard about, but oddly enough never see:p

you've got to be kidding me!!!!!!!!!! that's like the only thing that makes being a woman worth it! ask any of the bfs, they'll tell you!!!! they get tired of feeling studded out/ getting used up!!!!!! besides, they can only cum once at a time (the poor things!!!) , and then you have to wait another half a fucking hour, and that's if you're lucky!!!! sometimes you have to take care of the business on your own. not necessarily fun, but necessary. 2 bfs brought "help". oh those were glorious days!!!!!!!!!! no one can keep up. the high i get from sex is better than the high i ever got from coke!!! i feel sorry for guys. thank GOD for multiple orgasms!!!!!!!!!!!!!!

that or i'm just some no-good, two-bit sex addict. just talking about this is making me feel- er- nevermind. :D

EDIT~~~> maybe i should mention i'm a synesthete. might have something to do with it. idk

Hiram

01-03-2009, 01:31 PM

Yes, u can use vaginal as a ROA on certain meds. I know a few patients that had to administer certain meds this way

I'm still a little skeptical since of course I reside in the Show-Me State. :p

Angelwolf13

01-03-2009, 01:34 PM

pfft. i'm like the only girl i know who picked up a guitar to get laid. ;)

ZodiacKiller

01-03-2009, 01:37 PM

pfft. i'm like the only girl i know who picked up a guitar to get laid. ;)

Haha! Talk about turnin' the tables, eh? So how'd it work out for ya??

ZK

Angelwolf13

01-03-2009, 01:40 PM

Haha! Talk about turnin' the tables, eh? So how'd it work out for ya??

ZK

yowzer!!!!!! hehe!!!!!! :cool:

blutuesday

01-03-2009, 01:42 PM

I'm still a little skeptical since of course I reside in the Show-Me State. :p

You only said that because you KNOW I do too.

I SHOULD give u some disgusting textbook photo to look at here, but I shall refrain.

Spiritualized

02-26-2009, 12:14 PM

Back when I was afraid of needles I made myself a Dilaudid douche. I sat upside down with my back to the wall for 20 minutes, and yes, it works girls.

sweet pea

02-26-2009, 12:26 PM

Back when I was afraid of needles I made myself a Dilaudid douche. I sat upside down with my back to the wall for 20 minutes, and yes, it works girls.

i love that this is your first post! hilarious!!

i might just be crazy enough to try this when i get my hands on something good!! will report back.

should i crush it up, or crush & mix w/ water?? or just the whole pill?? jesus, these questions are making me lmao. i'm being serious though.

losangeleslifer

02-26-2009, 12:42 PM

Back when I was afraid of needles I made myself a Dilaudid douche. I sat upside down with my back to the wall for 20 minutes, and yes, it works girls.

I'm having trouble getting a visual of that. Any chance you have it on any digital media?

Just kidding.

I don't believe we have been formally introduced.

chemiKalz

02-26-2009, 01:06 PM

all i have to say is bike pumps and cats

edhorfin

02-26-2009, 04:03 PM

"Gina White, anyone?

Suboxstitute

02-26-2009, 04:50 PM

I went to the drugstore and asked for K-Y gel with suboxone enhancer; they looked at me real funny so I left.

Maybe you could stick a pill on the top of a tampax with something like KY which is safe for internal use.... and get the pill up there ( you'd have to leave the tampax for a while or I'll bet it would come right out.....and hope it stays therenuntil it dissolves. Still a little leery of this new ROA.

But I have to admit it does make me curious. I am due for a sub soon as well. Gotta admit i'm thinking bout it. Sub-lingual gets boring.

Princess, don't you fuckin DARE give me a hard time about this!

Sue

P.S. And as for the nether region issues, we could call this dopin'lingus. Get it? Get it?

Angelwolf13

02-26-2009, 07:42 PM

i love that this is your first post!

so do i!

and thank you, spiritualized. what a visual! you definitely belong on this board.

Spiritualized

02-27-2009, 10:50 PM

Haha, well I figured I should chime in on something I had experience on. :p This is more or less bang on,
except duh, not the rectum:

http://forum.opiophile.org/showthread.php?t=1882

Basically mix with water then squirt it with an oral syringe.

skabbo

02-27-2009, 11:00 PM

you took the words right out of my mouth! is there a case study? i'd like to volunteer!

"fucking girls into euphoria", i love it! pandora, you're a genius!!!!!!!

p.s. i haven't tried it yet. still waiting for mr. fent to come along.

Considering Fent works pretty damn well transdermally, I think Mr. Fent would be unconscious, drooling, with a big smile on his face, but pretty much worthless for your purposes :D