Hello & a question re:Opana ER

[Camel_Guy]

First of all, I just wanted to say hey. I've scanned these boards for years and finally found myself a member. For that, I'm grateful. So, to all of those hundreds and thousands of posts that have provided me with wisdom in the past, thank you. For those that will do so in the future, thank you, too.

Speaking of wisdom. Why not start now. SWIM recently acquired a new type of medication. He's infinfitely familiar with tons of other opiods, but not this one and the resources on the net seem to be a bit contradictory. He asked me the best way to get the most from this medicine. It's 40mg Opana ER. My understanding is that the oral bio-availability of this is only like 10%. I also have a feeling that this is so strong that it would be easy for swim to OD, even though he has unbelievable tolerance (as recently as last week, he was prescreibed 4 80mg OC daily and 30mg Roxy prn every 6hrs for BT and he used it all and more and kept running out. In an attempt to placate his doctor, he asked to try something different. But now he wants to know how to best use this. to waste 90% of it by taking it as prescribed seems insane, so he tells me. What should I advise him?

So far, the only thing I know to tell him is that alcohol increases bioavailability of it UP TO 70%, so he should cut the pills into quarters, chew them and swallow with a couple of shots of whiskey. Is this sound advice? I'm sure he'd be much happier with whatever the experienced people here could come up with.

Thanks again for allowing me into your ranks. I hope to be able to be a nice member of the community and I look forward to making lots of friends!

[WarmCyanide]

Welcome to Opiophile! Alcohol will def have an effect. but IMO is not the best. try other potentiators. type "potentiators" in the search engine and you'll get some good info. Lookin forward to getting to know ya!

[PdoubleE]

I dont think Alcohol will potentiate the bioavailability that much.. I think It will allow the pill to release that much at once if I am correct. I found The best way to do the ERs is to insuffilate them even know it sucks and taste like a nasty garlic-y food product mixed with silicone and narcotic ~Gag~. But its def worth the high :D You can try to IV.. But I think its a real bitch!

[bronyraur]

Welcome to Opiophile, Camel_Guy.

Make sure to keep your hands inside the ride at all times. And keep your cats (if you have any) away from Duckfeet–he's been know to have *issues* with them.

Have fun, follow the rules (http://forum.opiophile.org/showthread.php?p=146), and be safe.

[Synack]

I believe it was 270 or 290ml of 90% ethanol that changed the bioav to 70% - also keep in mind the change is variable.... just crush it and snort it.. works for my neighbor - that damn druggie.

[Camel_Guy]

Thanks for all of the kind welcomes and for the advice regarding my question. There are a lot of genuinely nice people hanging out around here and I hope to be considered the same along the way. Meanwhile, I'll be looking forward to making some new friends and if possible, putting in my own two cents here and there.

Thanks again guys. I'm happy to belong and after Christmas, when times are a little easier, I'll try to make a little bit of a donation, too. After all, this isn't exactly the great site that it is by some mystical, magical means. It's obvious that a lot of hard work and money are the main ingredients. It truly is a wonderful place and I can say that, because I've been lurking for what seems like an eternity now. Now though, I'm proud to belong! TC all and if I don't post in this thread again before then, Merry Christmas!

[Larry]

Hi there and welcome to the board, I gotta say DAMN your rx 4 80mg oxy + 30mg roxi for bt meds geez if you dont mind me asking what is your ailment, thats a pretty crazy rx... I wish I had that under my christmas tree this season hehe

larry

[Camel_Guy]

Hi there and welcome to the board, I gotta say DAMN your rx 4 80mg oxy + 30mg roxi for bt meds geez if you dont mind me asking what is your ailment, thats a pretty crazy rx... I wish I had that under my christmas tree this season hehe

larry



LOL

Well, it's had a lot to do with luck and finally finding the right doctor. I suppose that it took years for me to get to this point, though. Back when I first started pain mgmt, I was on 2 40s per day and that was it. It took care of the pain AND gave me that sweet euphoric feeling. As time went by though, things got worse and worse. There's a brief description of my medical condition in my profile, but to save you the trouble, I'll just say that I ended up having a zillion more surgeries and as of now, I have metal going from the top of my T-Spine to the very bottom of my L-Spine. I'm lucky to be walking and am informed that without future surgeries to remove scar tissue that impinges on nerves, I'll end up in a wheel chair. Of course, more surgeries leads to more scar tissue, though. So, I'm in no hurry for anymore surgeries. Essentially though, when I moved here to NC, I had A LOT of trouble getting into pain mgmt here, even WITH all my records from KY. My pain was being under-treated to the max and I had NO LIFE, WHATSOEVER. I ended up making one of the stupidest decisions of my life, but it ended up having the best consequences. I had given up and decided I couldn't live with the pain anymore. I took a full bottle of 120 10mg Valiums and a bunch of other medicines all mixed together. I did this after my wife went to bed and after leaving several notes to different family members, explaining that I just gave up and couldn't live this sort of life.

The idea was I'd be dead by the time she got up (in several hours), so there'd be no chance of any intervention that would save me. Apparently, God wasn't ready to let me go, because she woke up, found me unconscious on the couch, with the notes and all the bottles. An ambulance ride to the hospital that I have no memory of and waking up in ICU 4 days later was the result. At the hospital, I met a VERY cool psychiatrist. We had many talks. In addition to telling me how close I'd come to death (apparently it was truly a miracle that I lived, Thanks be to God!), he ultimately decided that I wasn't a psych patient and that my suicidal ideology(sp?) was due only to my untreated/under-treated chronic pain condition. He hooked me up with a new family doctor that was a friend of his (in addition to formerly specializing in pain mgmt) and he immediately started me on 3 40s per day with 15s for BT and we began going up from there, until I began to feel more and more normal and to actually increase my activity without added pain. I've tried nearly every drug known to man and I've used and abused too, in an effort to self-medicate, which has obviously led to even more problems. Now though, things are MUCH better.

Just recently though, a friend of mine in a similar situation, (SWIM is his name), told his doctor that he was tired of the extremely high dosages of OC and Roxy and asked if there were other options. So, the doctor is maintaining the BT oxy, but starting to titrate up on the new medication (the 40mg Opana ER), which led to SWIM asking me about how to best use them at such low levels until he sees the doc again and gets up to a higher, more equivalent level, because his pain is already much worse. No w/d, just lots of pain. I expect that he'll go up to somewhere around 160mgs of the Opana ER next month (because my understanding is that 160mg of Oxymorphone is the equivalent of 320mg of Oxycodone) and then maybe go to one or two 8mg Dilaudids every 6-8hrs or so for the BT and that should do the trick and be somewhat more equivalent to the OC doses that he's been on. If all of that works out well for SWIM, then I hope to follow in his footsteps.

The major problem I'm having in helping him with advice is that there doesn't seem to be a lot of info on Oxymorphone, which is what the Opana is. The Dr stated that OC is turned into Oxymorphone, so that this is just a straighter dose that doesn't need to be converted by the liver. The oral bioavailability sucks, though. SWIM was much more interested in a long-acting HYDROMORPHONE, not OXYMORPHONE, but learned that there was no such drug approved in the USA. So, barring any recommendations from you guys, SWIM is gonna try the route I've described above. Hopefully, this answers your question(s) and additionally, maybe it'll give others a little more 411 to maybe give us some ideas as to where to maybe go with this. Like SWIM, I just really wanna get away from the OC, because I'm on mega-doses and I dislike the stigma associated with it, in addition to the fact that it seems to just keep going higher and higher over the years. I'd like something that has less stigma and will do the same job without having to be titrated so often. Lastly, I'm not gonna lie. SWIM tells me he really loves the euphoria and that he lives for it, IN ADDITION to the pain relief. So that needs to be just about as much a consideration as the pain relief.

Anywho....sorry for the novel. Sorry as well that I can't help with the Christmas tree thing. Who knows though, maybe you'll get a new Jaguar instead or something. :P

TC friend and sorry again about the novel.

[austinslacker]

I was on 120mg Opana ER and the best way I thought was insufflating them. Some folks told me one gets about 60% bioavailability this way. That was my DOC and use. I know when used this way, it was equivalent to about 40mg=120 oxy railed, something in that area. Be very careful with the Opana ER, potent via insufflation

[Duckfeet]

Welcome welcome!

First of all, I just wanted to say hey. I've scanned these boards for years and finally found myself a member. For that, I'm grateful. So, to all of those hundreds and thousands of posts that have provided me with wisdom in the past, thank you. For those that will do so in the future, thank you, too.

<snip>

Thanks again for allowing me into your ranks. I hope to be able to be a nice member of the community and I look forward to making lots of friends!

[Camel_Guy]

Thank you, VERY much, to all of you! You guys really know how to make a new person feel welcome! I thought I knew a lot about this site. It's a Godsend for those looking for information and the ability to freely discuss what's unfortunately a taboo subject in most places. I hadn't a clue as to how friendly it could be, though. Thanks for showing me this! Take care, each of you and warm holiday wishes from my family to you and yours in the coming weeks.

[chopstix]

Yup, rail that shit. It does gel and it feels weird up there, but it works...

[farmpkm]

I believe it was 270 or 290ml of 90% ethanol that changed the bioav to 70% - also keep in mind the change is variable.... just crush it and snort it.. works for my neighbor - that damn druggie.

270ml of 90% alcohol is equal to about 15 shots of whiskey (or anything else). I dont know about you, but 15 shots would floor me even without the Opana.

They are extremely difficult to IV... just turns to a super-thick gel. I'd say prep it like you were going to IV, and squirt it up your ass. Anyway, IV'd Opana always made me so sick I wanted to die. Gave me a cotton-fever like sickness, only it was probably worse. Happened twice with several weeks in between, so I know it wasn't the same batch of pills or same shooting gear. Weird. I'll never do that again.

[Deadfiend]

Hay Camel_Guy all I got to say is welcome and damm it sounds like you docs got a damm good writing arm....

[RFE]

I have a huge deal of experience with Oxymorphone. I've been using 80mg IV daily via 10mg instant release and I can tell you that the ER (extended release) version needs to be insufflated in order to get any kind of reasonable bioavailability. In addition to this, you should be aware that oxymorphone will drastically raise your tolerance to OC and other opioids. After the above dosage, I was no longer able to use 1-2 full OC80s to stop w/d's. Similarly to fentanyl, this stuff will raise your tolerance to hell and you will wish that you never switched. Since my tolerance has never returned back to acceptable levels, I am now using bupe on/off for 3 weeks at a time. Enjoy safely

By the way, I don't see how you could survive 120 10mg diazepams, that is truely a miracle.

[chopstix]

270ml of 90% alcohol is equal to about 15 shots of whiskey (or anything else). I dont know about you, but 15 shots would floor me even without the Opana.


Seriously not trying to brag or anything, mebbe Im just a lush, but if I'm running, a pint of whiskey and only an opana ER (40mg?) for an evening would be on the bottom end of "about right" - and that's since I was about 22..

[ryan]

SWIM has recently just got into Opana ER.
SWIM gets the 20 mg green ones.

SWIM tried to inject them with no luck...as everyone else said, they gell up like no other when you put them in the spoon and add water. There's no way to defeat the timerx silicone crap that protects the precious oxymorphone that we so desire in our veins.

Unless someone has a way?

Snorting them is a pain too, but it will work. They do gell up in your nose, and they taste like how a deep fryer smells. SWIM says this is the best way to take them. Which sucks, especially if you are into needles.

SWIM has a pretty big tolerance (10-20 bags of mid grade powder heroin IV'd daily) and says that it takes about 3-4 20mg pills insufflated to get high. SWIM is going to try to use these opana er's to get off of heroin.

[pharmboy]

Warning this is a theory :: I have not tried this :: I take NO resposibility !!



OK having said that, someone once came up with making a stand in stomach

in a jar , you put in water and enough lemon juice or vinigar to make the

PH the same as stomach acid which I dont know and drop the opana in

and let sit for twelve hours. You might want to gently shake every now

and then, then you strain the water from the goo and balance back to

7 with baking soda and filter. Like I said it's a theory.