Fuckin Tramadol...

[HandMeSomeOpiates]

I am so thankful for it but maintaining on it for more than a week sucks ass. It just feels dirty. Barely even a hint of opioid feeling. BUT, I'm not sick so I'm thankful. Just feel weird. I take about 300mgs a day. It makes me so jittery and speedy. I'll be walking around the house trying to find something to do, but when I do find something to do I don't wanna do it. Trams are a very weird drug but I am in debt to it. Just thought I'd get this off my chest. Anybody else maintain on Trams?

[Narkotikon]

I've only taken Tramadol once. I was prescribed it at an UTC because it was there policy to not give anything stronger I guess. At the time I did get a slight buzz from it, but it wasn't really what I would call and opiate high. Didn't really get rid of the cravings or anything, just got me through the night until I got something else (pods). I don't know if it would be useful for maintaining for me right now though. I thought diphenoxylate (Lomotil) had more of a kick than tramadol.

[HandMeSomeOpiates]

I've only taken Tramadol once. I was prescribed it at an UTC because it was there policy to not give anything stronger I guess. At the time I did get a slight buzz from it, but it wasn't really what I would call and opiate high. Didn't really get rid of the cravings or anything, just got me through the night until I got something else (pods). I don't know if it would be useful for maintaining for me right now though. I thought diphenoxylate (Lomotil) had more of a kick than tramadol.
I would love to have pods as a backup but I swear to you they do not like my body or something. I've made tea, filled caps, mixed with OJ with very little effects. I put 10 mediums and grinded them, made tea, forced the vile shit down and was highly disappointed. I have been trying to get that pod high everyone talks about but I can never find it.

[Narkotikon]

I would love to have pods as a backup but I swear to you they do not like my body or something. I've made tea, filled caps, mixed with OJ with very little effects. I put 10 mediums and grinded them, made tea, forced the vile shit down and was highly disappointed. I have been trying to get that pod high everyone talks about but I can never find it.

Hmmm. I've heard other people say that. I'm not sure why they don't work. I mean, I guess it could be bad pods, but really I find that hard to believe. Even if you have incredibly weak pods, they're still going to have some morphine in them. You just have to use more. I believe the people when they say they don't work, I just don't understand why. I'm guessing it's because they prefer other opiates and have higher tolerances, or because they prefer other ROA's. I'm not really sure. I just know they work for me, and I love them.

I will say that, when you're new to pods, it takes a while to get used to. I mean, the first time I drank tea I think I used ten pods, and I didn't really know what I was supposed to look for. At that time, I was more into Vicodin / Tussionex, so I was expecting that kind of high. What I'm trying to say is that pods take getting used to. I didn't really get high and nod until the second or third time. But, you said you have tried several different methods, so I don't know what the problem is.

[resorcinol]

I can easily see why somebody wouldn't like pods.

I think HMSO probably is "feeling it", it's just not what he expects.

Morphine is a dirty drug, both pharmacodynamically and in real life. It has stronger sedative and even mild psychedelic effects in high doses, and is more likely to make you nod than semi-synthetics are (a high morphine or pod dose can stick you right to the bed / couch like glue). It hits kappa receptors as a weak agonist, which is what I suspect causes the irritability some people feel from it, and also the mild psychedelia that some people feel in high doses. It also hits delta receptors as a weak agonist -- the effects of which are unknown (psychoactive at least.... delta agonism seems to increase antinociceptive potency).

Oxycodone and hydrocodone are clean mu-selective opioid agonists. Sure, they have weak affinity for k and delta too, but far weaker than morphine's (already kinda weak) agonism of those receptors. This results in a cleaner mu high, and a SPEEDIER high, since mu and only mu can increase downstream dopamine release in the NAc when activated. Combined with less sedation due to less k and delta activation, you feel speedier than you would on morphine.

Personally, I notice the dopaminergic effects of ALL opioids, including pods and morphine, but I must admit, they are more noticeable with especially oxycodone. If you're looking to recreate oxycodone's high with pods and some other drug... amphetamine or dexmethylphenidate in a low dose might approximate it (taken w/ pods or morphine).

As far as tramadol goes, it's an extremely odd drug. I'm convinced that only 30% or so of it's psychoactivity is actually from mu agonism... the rest has got to be some kind of monoaminergic activity... almost 1st plateau DXM-like. It's strangely enjoyable, but I like my opioids to be mostly opioids and not all that other stuff, so I'd take even dihydrocodeine or maybe codeine too over it. The only opioid I'd refuse in favor of tramadol is d-propoxyphene... that stuff sucks even more than tramadol... it's BARELY even CNS active as far as I can tell.

[resorcinol]

I can easily see why somebody wouldn't like pods.

I think HMSO probably is "feeling it", it's just not what he expects.

Morphine is a dirty drug, both pharmacodynamically and in real life. It has stronger sedative and even mild psychedelic effects in high doses, and is more likely to make you nod than semi-synthetics are (a high morphine or pod dose can stick you right to the bed / couch like glue). It hits kappa receptors as a weak agonist, which is what I suspect causes the irritability some people feel from it, and also the mild psychedelia that some people feel in high doses. It also hits delta receptors as a weak agonist -- the effects of which are unknown (psychoactive at least.... delta agonism seems to increase antinociceptive potency).

Oxycodone and hydrocodone are clean mu-selective opioid agonists. Sure, they have weak affinity for k and delta too, but far weaker than morphine's (already kinda weak) agonism of those receptors. This results in a cleaner mu high, and a SPEEDIER high, since mu and only mu can increase downstream dopamine release in the NAc when activated. Combined with less sedation due to less k and delta activation, you feel speedier than you would on morphine.

Personally, I notice the dopaminergic effects of ALL opioids, including pods and morphine, but I must admit, they are more noticeable with especially oxycodone. If you're looking to recreate oxycodone's high with pods and some other drug... amphetamine or dexmethylphenidate in a low dose might approximate it (taken w/ pods or morphine).

As far as tramadol goes, it's an extremely odd drug. I'm convinced that only 30% or so of it's psychoactivity is actually from mu agonism... the rest has got to be some kind of monoaminergic activity... almost 1st plateau DXM-like. It's strangely enjoyable, but I like my opioids to be mostly opioids and not all that other stuff, so I'd take even dihydrocodeine or maybe codeine too over it. The only opioid I'd refuse in favor of tramadol is d-propoxyphene... that stuff sucks even more than tramadol... it's BARELY even CNS active as far as I can tell.

[HandMeSomeOpiates]

I can easily see why somebody wouldn't like pods.

I think HMSO probably is "feeling it", it's just not what he expects.

Morphine is a dirty drug, both pharmacodynamically and in real life. It has stronger sedative and even mild psychedelic effects in high doses, and is more likely to make you nod than semi-synthetics are (a high morphine or pod dose can stick you right to the bed / couch like glue). It hits kappa receptors as a weak agonist, which is what I suspect causes the irritability some people feel from it, and also the mild psychedelia that some people feel in high doses. It also hits delta receptors as a weak agonist -- the effects of which are unknown (psychoactive at least.... delta agonism seems to increase antinociceptive potency).

Oxycodone and hydrocodone are clean mu-selective opioid agonists. Sure, they have weak affinity for k and delta too, but far weaker than morphine's (already kinda weak) agonism of those receptors. This results in a cleaner mu high, and a SPEEDIER high, since mu and only mu can increase downstream dopamine release in the NAc when activated. Combined with less sedation due to less k and delta activation, you feel speedier than you would on morphine.

Personally, I notice the dopaminergic effects of ALL opioids, including pods and morphine, but I must admit, they are more noticeable with especially oxycodone. If you're looking to recreate oxycodone's high with pods and some other drug... amphetamine or dexmethylphenidate in a low dose might approximate it (taken w/ pods or morphine).

As far as tramadol goes, it's an extremely odd drug. I'm convinced that only 30% or so of it's psychoactivity is actually from mu agonism... the rest has got to be some kind of monoaminergic activity... almost 1st plateau DXM-like. It's strangely enjoyable, but I like my opioids to be mostly opioids and not all that other stuff, so I'd take even dihydrocodeine or maybe codeine too over it. The only opioid I'd refuse in favor of tramadol is d-propoxyphene... that stuff sucks even more than tramadol... it's BARELY even CNS active as far as I can tell.

Wow very informative reply. Thanks for that.