PDA

View Full Version : Finally - Constipation Cure!


twstedroads
10-23-2008, 06:25 AM
Relistor (methylnaltrexone bromide injection) is now available at your local pharmacy and is indicated for constipation caused strictly from opiate when other laxatives wouldn't work. I've been waiting for this drugmto come out for some time now and am going to the pharmacy to pick up now since int is ready... i will let everyone know my results. And no, it wont put you into withdrawals because it has the inability to cross the blood brain barrier thus leaving your CNS unaffected, but your bowels empty.

Do some research, the only promblem is that it is fairly expensive.

There goes one more reason to get off methadone out the window!

EleusisII
10-23-2008, 06:34 AM
I've always imagined, that the best cure for constipation, is a good ol' fashioned anal dick-pounding, but this also sounds like it might be effective.
How much does it cost?

OxyContinuously
10-23-2008, 08:35 AM
so that methyl-naltrexone stuff is available OTC? and it's an injection as well??

have u tried it, is it any good?

bronyraur
10-23-2008, 02:30 PM
I've always imagined, that the best cure for constipation, is a good ol' fashioned anal dick-pounding, but this also sounds like it might be effective.
How much does it cost?

I'd go out on a limb and say that an anal assault (tee hee) would be quite effective. Although I'd much rather try what the OP mentioned first. I know that it is a difficult decision (ass pounding vs. injection), but I'm willing to bet the injection would be more popular with the general (opiated) public.

Consumed.
10-23-2008, 02:36 PM
I've always imagined, that the best cure for constipation, is a good ol' fashioned anal dick-pounding, but this also sounds like it might be effective.
How much does it cost?


Fuckin disgusting but made me laugh hard! No pun intended there, no seriously im not kiddin, in fact its shriveling thinking about that

earthenone
10-23-2008, 02:37 PM
yes I'll have the syringe please, no sir ill pass on the dick butt thanks!

Indy
10-23-2008, 03:51 PM
so that methyl-naltrexone stuff is available OTC? and it's an injection as well??

have u tried it, is it any good?

Nah RX only unfortunately, but i don't think it's scheduled so in a few months there might be some online pharmacies stocking it.

SlimContin420
10-23-2008, 04:54 PM
Constipations' a bitch!!!!! I've been taking it so long that the only side effects I get dry mouth and NODS. HELL YEAA!!!!

Lets take into account I've only been on it (illegaly) for about 4 - 5 years. The beginning I couldnt shit to save me Life, and the ASS POUNDING will never be a solution!!!!

I-Nod
10-23-2008, 06:10 PM
Constipations' a bitch!!!!! I've been taking it so long that the only side effects I get dry mouth and NODS. HELL YEAA!!!

Bullshit

bronyraur
10-23-2008, 07:04 PM
Bullshit

+1

I don't think I've ever met anyone who used opiates regularly that didn't suffer from constipation.

Mallinckrodt
10-23-2008, 07:51 PM
+1

I don't think I've ever met anyone who used opiates regularly that didn't suffer from constipation.

+2

twstedroads
10-23-2008, 08:54 PM
Okay, here goes. Make sure you take this at your own risk. It is a subcutaneous injection btw sorry. Within four minutes of the injection, I could feel my bowels moving all around and was happy it was working. Well, I did in fact eventually shit, but I was also vomiting uncontrollably, very cold, and went into the most significant withdrawals of my entire life. Luckily my father is an MD and I went to his office to have one of the nurses administer it to me for the 1st time (just in case). They immediately hooked me up to a fluid IV and gave me a bedpan and gave me a shot of phenergan, which was fantastic because I eventually fell asleep. It was a very odd sense of withdrawals though, and the most painful part were the 25 sec apart EXTREME gas pain. After waking up after all of the fluids were in me, I drove home, took my methadone dose and lied in the bath. The relistor absolutely did NOT block the methadone however, and I got a very good nod going. I am baffled by why it made me feel so shitty. I can honestly say though, that this morning was the most painstaking event I have ever been forced to go through, and the fact my bowels are empty as can be is hardly worth it. I think that the reason it was so bad was because it had been several days since my last BM and had been taking several OTC laxatives including sennosides, miralax, and docusate sodium. Maybe my colon was so messed up it made the expperience worse than normal. I will say that it DOES in fact send you into withdrawal land, even though it has no effect on blocking any opiates taken in the hours after it was administered.

I was very much the guinea pig in this experiment and hopefully you guys can take my experience and draw your own conclusion.

And price wise, my father (the doctor) is friends with the local pharmacist and I paid cost for one dose (vial). So the pharmacy gets the one dose, 12 mg/.6mL for FIFTY DOLLARS. If taken regularly though, you are only supposed to dose every other day.

So like I said, please use Relistor at your own risk and I wanna predict today that in the near future, it will be recalled, changed, or taken off of the market altogether. Good luck guys, and happy shitting (no dicks though please!)!

oxymoronluvr
10-23-2008, 11:06 PM
i posted this months ago. it was avalible this summer. a friend of mine is on it. he is on suboxone and is having great results with it. it is around 50 bucks a dose. medicade pays for it so thats great. it comes in "kits" that have little packs with a needle, vial of med, 2 alcohol swabs all in a nice tray. but it works. and works wonders.

and my friend poops regurlarly on 16mg of subxone a day. i can't see how it can cause w/ds cause it only works on the guts.

Duckfeet
10-23-2008, 11:42 PM
Yeah, I'd read about that, some study of--I think--older patients on longlasting opiates, and it seemed *so* hopeful...maybe it was on here, and it was you that posted it, but anyway, thanks again...

Funny thing is, it was mostly constipation that sort of forced me into a slow, serious withdrawal plan from methadone maintenance...may seem sort of funny/weird/lightweight, but I'm sort of a proud man, and it was getting *so* depressing to have to give myself daily coffee enemas, and taking all kinds of laxative, and being twice in ER's in this year, after week of constipation, that I finally decided I just couldn't take it anymore, and had to get off of these long lasting opiates--bupe does pretty much the same thing to me, probably added to fact I'm older than most of you, and nothing "flows" as good as it once does...who knows...

But anyway, to me, this is always major--and worst--side effect of methadone maintenance, and I go to monthly "group" for mdone vets at V.A. hospital, and constipation...and lethargy/sleeping too much, lack of interest in life, drinking, etc., are main problems of all these older vets--most in fifties or older--and I was healthiest looking one of all, tho it is me saying it...

But in any case, once I got down around 20mg methadone, my bm's got normal again, and morning are now "happy time" again for me...and I'm at 5mg daily, *way* down, and about finished, and haven't had a really bad day since I started drop, and between yoga, and now *bodysurfing*:) again, feeling reasonably optimistic and even cheerful about my chances...and it's been almost three years since I've had a day off opiates...and I'm stone junky, so "we'll see...", but I can't help that I'm starting to get actually "hopeful" and I had forgotten what that felt like...


Relistor (methylnaltrexone bromide injection) is now available at your local pharmacy and is indicated for constipation caused strictly from opiate when other laxatives wouldn't work. I've been waiting for this drugmto come out for some time now and am going to the pharmacy to pick up now since int is ready... i will let everyone know my results. And no, it wont put you into withdrawals because it has the inability to cross the blood brain barrier thus leaving your CNS unaffected, but your bowels empty.

Do some research, the only promblem is that it is fairly expensive.

There goes one more reason to get off methadone out the window!

I-Nod
10-24-2008, 06:26 AM
^^^ Man, Duck, that is friggin awesome... down to 5mgs AND things are starting to look up!! Proud of you, man, I really am. That's a gigantic obstacle to hurdle. Seriously, reading that just brightened my whole morning... I just might chase down a neighborhood cat in honor of your success so far. :D I don't think using a 2.5gal 4horse compressor is a good idea though... first time I ever seen the white in a cats eyes, when I rolled that compressor out of the garage. :cool: Great job, Duck... keep on keepin on, man!!!


EDIT: Sorry fur goin off topic. On that note: thanks for reporting your experience twsted. Would hate to waste 50$ on a full-body evacuation from every orifice. heh.

OxyContinuously
10-24-2008, 08:39 AM
u know what?

forget about how good or bad it is for constipation---i would never put anything in my body that has the word "naltrexone" in it...bottom line, end of story, close this thread j/k

Opiyum
10-24-2008, 05:18 PM
When it comes to constipation I have recently been having great success with a daily dose of 4 oz. of Activia yogurt. Not only does it taste good but I have now been having regular BM's on a daily basis which I haven't had for six or seven years. I'm not 100% "regular" but I am in a much better state and couldn't be happier. One day I actually shat out one solid uniform log instead of little rabbit turds. I would definately recommend it to any junkie looking to get regular.

EleusisII
10-24-2008, 05:35 PM
I gotta say, with time and tolerance constipation gets better for me. I don't even get as half as constipated as I used to be...

But it's interesting... Sounds like every junkie got his own cure for constipation...

You got your yoghurt, I fight the good fight with my world famous coleslaw, Brony's favorite is a good ol' fashioned meat injection...

(Don't try to deny it now... We even have the quote to prove it... I'd go out on a limb and say that an anal assault (tee hee) would be quite effective. )

Hmmm... Dare I take this thread there? Yes! YES GODDAMNIT!

(Put's on british accent, to make it a tad bit classier!)

I say, friends and fellow opiophiles! I'm not a frequent practitioner of rear-entry-raiding, but for those of you that partake, does opio-enduced constipation change anything? Does it make the road to the brown star easier or harder?

Pandora
10-24-2008, 05:43 PM
I'd go out on a limb and say that an anal assault (tee hee) would be quite effective. Although I'd much rather try what the OP mentioned first. I know that it is a difficult decision (ass pounding vs. injection), but I'm willing to bet the injection would be more popular with the general (opiated) public.

I feel like an anal pounding would have the opposite effect. Ya know, pack it all in there. Haha, yuck.

To each their own, I guess. I've been pounded in the ass, and it never worked to alleviate constipation in my experience. Sorry if that's over-sharing haha. :p

I-Nod
10-24-2008, 05:53 PM
^^^ Share away :D

Pandora
10-24-2008, 05:55 PM
^^^ Share away :D

Haha, oh I-Nod.

Not to derail the thread, but how the hell are ya man? I feel like I haven't talked to you in ages! Hope all is well with you! :)

Love,
Pan

EleusisII
10-24-2008, 06:11 PM
He's great! He's fine, everyone's ok...
Could we get to your ass-pounding experiences now?

Duckfeet
10-24-2008, 06:40 PM
Following this thread, now *avidly*!!!^^^^:D

Yeah, we're all doing great: Pandora: don't leave us *hanging!!!*

Seedy
10-24-2008, 06:45 PM
Ass pounding aside, when I get really blocked up I use a tiny dose of naltrexone, like about .3mg (I just crush a revia pill and dilute with water). Call me crazy if you want but it works wonders. I do it first thing in the morning, there's very little discomfort, it's just enough to empty the bowels, and also makes the first dose of the day kick in better.

EleusisII
10-24-2008, 06:46 PM
Following this thread, now *avidly*!!!^^^^:D

And if you're as crafty as I am, you're already sitting on your hand too! :D

Duckfeet
10-24-2008, 07:15 PM
Just think, Pandora: now you have countless men, all over the fucking *world* staring at their computer screens with crazed deprived eyes, waiting for "further information..." Some of us lead rather dull lives in this area, and now have dubious intrusive imaginative thoughts and ancient memories of...well...oh...never mind ... ;)

Pandora
10-24-2008, 08:31 PM
Haha, you guys are cute. I don't know what details you are looking for exactly. I'm not the hugest fan of ass pounding myself, but I like to give my man what he wants, ya know? So I'm willing to take it as long as he's satisfied. My man gotta be satisfied. I don't know, do you want a run down? Get undressed, get my man excited with my mouth, lube him up, and sit on it! Then the ass pounding commences.

And the moral of the story: doesn't alleviate constipation.

If you desire more details, feel free to ask questions.

Love,
Pan

EleusisII
10-24-2008, 08:43 PM
Hmmnnhgghghhh Ahhhh!

Pandora
10-24-2008, 08:52 PM
Hey you. ;)

Maybe I can show you what I mean when I come to your lab for you to teach me about those particles. I still don't get it and need that analogy demonstrated.

Dan Steely
10-24-2008, 09:56 PM
Haha, you guys are cute. I don't know what details you are looking for exactly. I'm not the hugest fan of ass pounding myself, but I like to give my man what he wants, ya know? So I'm willing to take it as long as he's satisfied. My man gotta be satisfied. I don't know, do you want a run down? Get undressed, get my man excited with my mouth, lube him up, and sit on it! Then the ass pounding commences.

And the moral of the story: doesn't alleviate constipation.

If you desire more details, feel free to ask questions.

Love,
Pan

I gotta ? Does it turn you on at all? And when you say pounded do you mean like fast and hard and all? I've done it a few times but I've always been really nice about it.

Cool of you to be so open.

My turn. Turkey baster + warm water. Not the best set up but it did work and something had to be done.

runormal
10-24-2008, 10:08 PM
sorry i couldn't resist ...

EleusisII
10-24-2008, 10:18 PM
Hey you. ;)

Maybe I can show you what I mean when I come to your lab for you to teach me about those particles..

You'd be more than welcome sweety... But you already know, what takes place there :)

:whip:

oxymoronluvr
10-24-2008, 11:11 PM
they need to drop the price of relistor thats the only downfall. activia works for some but theres no facts. and if other things can't live in the human stomach how can a bacteria. the acid turns coins into digestible matter, i don't think a bacteria could live through that and make it alive into the gastro tract. just my theory.

Duckfeet
10-25-2008, 07:47 AM
Hahaha: I woke up way early, as usual, and do my qijong exercises before the sun comes up, and meditate, and get on here all spiritual and full of the universal peace, and read this, and drop right back into the damned gutter...where I belong...and *thrive!*....:)


Haha, you guys are cute. I don't know what details you are looking for exactly. I'm not the hugest fan of ass pounding myself, but I like to give my man what he wants, ya know? So I'm willing to take it as long as he's satisfied. My man gotta be satisfied. I don't know, do you want a run down? Get undressed, get my man excited with my mouth, lube him up, and sit on it! Then the ass pounding commences.

And the moral of the story: doesn't alleviate constipation.

If you desire more details, feel free to ask questions.

Love,
Pan

I-Nod
10-25-2008, 08:37 AM
Who woulda thought a constipation thread could be so.............. enteresting, I mean interesting. ;)

ZodiacKiller
10-25-2008, 08:39 AM
My, my, our Pandora is a wicked, nasty little creature, isn't she? I think I love her........:p


ZK

clinton
10-25-2008, 09:27 PM
Constipations' a bitch!!!!! I've been taking it so long that the only side effects I get dry mouth and NODS. HELL YEAA!!!!

Lets take into account I've only been on it (illegaly) for about 4 - 5 years. The beginning I couldnt shit to save me Life, and the ASS POUNDING will never be a solution!!!!





care to explain how?

twstedroads
10-26-2008, 01:36 PM
indeed, I would have never guessed this thread would turn into the ass-pounding talk. thank god for you pandora, otherwise this would just be plain... gay. thanks sweetheart.

ps - (no offense to those who are gay)