for tha chemists

[jonny-5]

ok so i have been curious about this lately, maybe one of my chemically inclined homies can help.

i was reading on wiki that naloxone is extremely closely related to oxymorphone, in fact its name comes from naloxone's chemical name N-allyl oxymorphone. to quote wiki, "Naloxone is synthesized (http://en.wikipedia.org/wiki/Chemical_synthesis) from thebaine (http://en.wikipedia.org/wiki/Thebaine). The chemical structure (http://en.wikipedia.org/wiki/Chemical_structure) of naloxone resembles that of oxymorphone (http://en.wikipedia.org/wiki/Oxymorphone), the only difference being the substitution of the N (http://en.wikipedia.org/wiki/Amine)-methyl (http://en.wikipedia.org/wiki/Methyl) group (http://en.wikipedia.org/wiki/Functional_group) with an allyl (http://en.wikipedia.org/wiki/Allyl) (prop-2-enyl) group. The name naloxone has been derived from N-allyl and oxymorphone."

so just out of curiosity, of course i dont have the knowledge or resources even if i wanted to, but would it be possible to convert naloxone to oxymorphone?

[robojunkie]

Your best bet is not to bother unless you have cyanogen bromide, and then something with which to reduce it. Not easily done, and if there remains any of the narcan you'll be fucked like christmas goose.

[jonny-5]

Your best bet is not to bother unless you have cyanogen bromide, and then something with which to reduce it. Not easily done, and if there remains any of the narcan you'll be fucked like christmas goose.

like i said, i was in no way planning to do this, just wondering if it could be done. thanks for the info. just curiosity of the mind and how chemistry works is all.

[pharmboy]

The Levophanol molecule is the mirror image of the DXM molecule but

getting that sucker to flip over takes a lot of fancy chemistry.