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norseman
07-18-2008, 05:23 PM
Not sure what the hell is going on lately, but no matter how much my buddy doses, be it; small, normal, or large he is finding that he becomes nauseous for the half life of the oxy. Its a little scary as in your damned if you do and your damned if you don't type scenario. If he doesn't maintain then he gets violently ill with w/d, but maintaining on the oxy he is feeling pukey and mildly dizzy all the time anyways!!!

Just wondering if anyone has ever experienced this nausea, and what remedies you might suggest? Also any idea why this is happening out of the blue like this?

If it matters my buddy has been maintaining on average of 4-500mg Oxy/day for the last week since this shit started.

jonny-5
07-18-2008, 05:31 PM
your "buddy" might wanna take a week or so to lower his tolerance a bit. thats a lot of fuckin oxy a day, and too much of anything can be toxic for the body.

Princess
07-18-2008, 05:32 PM
This happens to my niece and a few friends of mine. They take promethazine about an hour or so before dosing and it seems to keep the pukes away.

Can you get a script for promethazine or another nausea med?

norseman
07-18-2008, 05:44 PM
your "buddy" might wanna take a week or so to lower his tolerance a bit. thats a lot of fuckin oxy a day, and too much of anything can be toxic for the body.

Thanks for the advice Jonny, my buddy knows he has got himself a predicament, just for yours or anyones knowledge my buddy normally maintains on what seems to be an average amount of pods 1 cup/day and only gets lucky with pharms once a month so it would seem that anyone using a cup a day of pods if going to need this much. But yes I know its a lot its just hard to get things to a "normal" amount :o

This happens to my niece and a few friends of mine. They take promethazine about an hour or so before dosing and it seems to keep the pukes away.

Can you get a script for promethazine or another nausea med?

I have tried graval PTO mom, and didn't find it did anything maybe I havn't taken enough? Just 50mg, I wonder if it is similer? I will look into promethazine, I hope its OTC in Canada.

jonny-5
07-18-2008, 05:48 PM
ya dude ive found my self many times having to take a step back. for me at least, i build up a tolerance to the euphoria of heroin much faster than the sleepiness and other side effects, so once i get to a certain point i dont feel good from it anymore, it just makes me feel like shit then nod the fuck out. when i get to that point i have to just do the bare minimum to get well, luckily with heroin that isnt very much, and do that for a week or so and then i can finally enjoy it and i dont feel like shit all the time.

norseman
07-18-2008, 05:59 PM
ya dude ive found my self many times having to take a step back. for me at least, i build up a tolerance to the euphoria of heroin much faster than the sleepiness and other side effects, so once i get to a certain point i dont feel good from it anymore, it just makes me feel like shit then nod the fuck out. when i get to that point i have to just do the bare minimum to get well, luckily with heroin that isnt very much, and do that for a week or so and then i can finally enjoy it and i dont feel like shit all the time.

Ya man, I think you are exactly right about where i am at right now, I think I have lost the euphoria with Oxy and I am just searching for a nod or something to just knock me the fuck out and then do it all over again. All in all its not any good man. And I guess its just a big waste of pills, right. Still though, I have tried smaller doses like just enough to keep functional and still experiencing the nausea, but maybe like you said it just builds up and becomes toxic to your body. Its never easy!!

norseman
07-18-2008, 06:11 PM
Actually I just got to thinking, the week before this nausea started I had been playing round with benedryl for the first time trying to lower my tolerance and to potentiate and get a nod on again. So I am thinking maybe the benedryl screwed up my system??? Is that possible? Like a week of benedryl every night, could that mess your chemistry up enough that you get like this?

Princess
07-18-2008, 07:11 PM
I have tried graval PTO mom, and didn't find it did anything maybe I havn't taken enough? Just 50mg, I wonder if it is similer? I will look into promethazine, I hope its OTC in Canada.

I haven't a clue what graval is? I just know that promethazine seems to help the people I know that have the problem of nausea with oxy. Maybe you didn't take enough of the stuff? I'm not sure. Maybe try something else made for nausea?

resorcinol
07-18-2008, 07:13 PM
Actually I just got to thinking, the week before this nausea started I had been playing round with benedryl for the first time trying to lower my tolerance and to potentiate and get a nod on again. So I am thinking maybe the benedryl screwed up my system??? Is that possible? Like a week of benedryl every night, could that mess your chemistry up enough that you get like this?

It's not impossible. Diph is an anti-emetic b/c of its antagonism of H1 and mAch receptors, but I'm sure you know that already. It could be the "rebound" effect where your sensitivity to nausea inducing stimuli is increased from discontinuance of diph. But rebound usually diminishes fairly quickly and you're still getting nausea.

Are you constipated? When i got too constipated the nausea from opiates was unbearable to the point I couldn't take them orally b/c I'd puke the dose up before much absorbed.

jonny-5
07-18-2008, 07:15 PM
Actually I just got to thinking, the week before this nausea started I had been playing round with benedryl for the first time trying to lower my tolerance and to potentiate and get a nod on again. So I am thinking maybe the benedryl screwed up my system??? Is that possible? Like a week of benedryl every night, could that mess your chemistry up enough that you get like this?

hmm, i dont know. many people have been talking lately about nausea from oxy, i know that back when i was into oxy and pills that oxy was the one most likely to make me nauseous. mabey it just has a stronger effect on the GI system than other opis...couldnt say tho on the benadryl thing. are you prescribed oxy or are you getting it elsewhere? maybe you could find a different opiate to switch to for a week or so?

norseman
07-18-2008, 07:43 PM
It's not impossible. Diph is an anti-emetic b/c of its antagonism of H1 and mAch receptors, but I'm sure you know that already. It could be the "rebound" effect where your sensitivity to nausea inducing stimuli is increased from discontinuance of diph. But rebound usually diminishes fairly quickly and you're still getting nausea.

Are you constipated? When i got too constipated the nausea from opiates was unbearable to the point I couldn't take them orally b/c I'd puke the dose up before much absorbed.

Dude, thanks for thinking so highly of me, that I would actually understand that! But I feel really stupid cause I am not exactly sure I understand what you are saying. Let me know if I got ya, all right. Basically you are saying that because of the way Diph acted on my H1 and mAch receptors it could possibly increase my sensitivity to nausea now because I have stopped taking it?

This "Rebound" you described, is it a common occurrence with Diph, because this is the first time I have heard about it, and as a matter of fact its the first time I have ever used Diph in my life and yes I am still getting nausea and now its has been a week since I have stopped the Diph, but the nausea has not been as bad as earlier in the week, so I presume I am slowly getting better, or back to "normal". If it matters, I was taking 150-200mg of Diph per night for about a week straight and then stopped immediately when lady luck knocked on my door. I wonder was that a normal dose someone would take of the Diph for potentiating or was I being an idiot again and over doing it like I seem to be doing with everything else lately :mad: I couldn't find any dosage recommendations on Opiophile or anywhere else for that matter, so i just experimented until I found a dose range that was effective. If I would have known about this rebound effect I would have not messed around with this shit to begin with!!! This should be common knowledge so people can avoid getting in my situation!

Its funny that you mention constipation, because I have actually been more constipated then normally lately, but not too the point I am overly concerned about it. I have had major constipation in the past, much more then now and never had nausea associated with that, but it is interesting to know that the constipation can be a cause of nausea as well.

Anyways thanks for the knowledge Resorcinol, its much appreciated.

norseman
07-18-2008, 07:48 PM
hmm, i dont know. many people have been talking lately about nausea from oxy, i know that back when i was into oxy and pills that oxy was the one most likely to make me nauseous. mabey it just has a stronger effect on the GI system than other opis...couldnt say tho on the benadryl thing. are you prescribed oxy or are you getting it elsewhere? maybe you could find a different opiate to switch to for a week or so?

Ya man, i will be "forced" to switch back to pods in a few days, so I will know for sure then if its the Oxy like you said possibly having a stronger effect on the GI system then other opis. But I never noticed issues in the past with Oxy and the nausea. But you would think there is nothing "stronger" on the GI tract then pods considering all the alkaloids, molds, plant material in general etc...

resorcinol
07-18-2008, 08:10 PM
Rebound is a re-emergence of symptoms worse than before they were treated by a drug when it wears off, or the emergence of symptoms a drug suppresses when they weren't there in the first place when a drug wears off. It's a problem that plagues most drugs, especially receptor targeting drugs but others as well.

I kinda doubt it's rebound because you're still experiencing the nausea and especially now that I see you mentioned taking gravol which acts the same way as benadryl in fact it may be the exact same drug but even if it's another antihistamine it has the same mechanism.

Constipation was my best guess but if it's something that never happened to you before with worse constipation it's unlikely it would emerge now. I had that problem from the beginning, and it was very problematic if all I had on me was pods, because oral is the only ROA feasable with those unless I felt like extracting, which is kinda not something i felt like doing in w/d.

pharmboy
07-18-2008, 09:43 PM
Hay Norseman. your definatly the second or third person on here talking about

nausia with Oxy. Maybe its bad oxy.

Princess
07-18-2008, 09:56 PM
Wasn't someone just talking about this the other day? I think you're right pharmboy... this has come up recently and a few people responded to that last post that it happens to them as well. VERY interesting!



Hay Norseman. your definatly the second or third person on here talking about

nausia with Oxy. Maybe its bad oxy.

cg5
07-19-2008, 01:08 PM
im around there.. like 6 80's a day...nausea only happens for the first 10 minutes when i dose then goes away... try some pep bismol or get some promethazine or some gravol.. should do the trick

SKipper
07-24-2008, 05:28 PM
Something you can do is get otc promethazine (phenergan) from England. There are several pharmacies that have it, but I don't know if I can post where I get it? If not, then pm me and I iwll get it to you.

It is called "Avomine", maybe a google search will show you the way. Legit pharmacy, so you want find any real good stuff, but I take a half before I dose to keep the nausea away. It doesn't affect me too much, but most people get real sleepy from it

Hope this helps

rockbottom
07-24-2008, 06:41 PM
i use to puke every time i did a rush and drink water so iwould have something to puke out for the next ten hours--drink water -puke--high as fuck for 1/2 hr- nausea--drink water--puke high as fuck repeat--i don't know what the fuck was going on--but that only happened for awhile---then at another point in time i would puke just smelling the shit i was cooking--my brother just said "damn dude your a real junky--puking b4 you even do your rush" i still get nausea i always figured it was part of the high:p

norseman
07-24-2008, 06:55 PM
Thats the thing rockbottom, I always had some nausea when I pushed my dose to a certain point, and always thought well "now I am high" and the nausea would be part of it! But now I have been feeling sick and dizzy all day everyday and these are just maintanence doses.

gosh i really hope this doesn't stick with me... totally sick of it. and i hope its not something serious.

rockbottom
07-24-2008, 07:09 PM
i don't know about the dizzy---but the nausea for me is normal:rolleyes: