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jacky
02-23-2006, 02:06 AM
german chamomille, or matricaria recutita, appears to not only help to lower tolerance to morphine in morphine addicted animals, but also contains a compound called apigenin which apparently is a benzodiazepine agonist responsible for at least some of this flowers sedative and hypnotic like effects......

this sounds like a good plant to mix with dan shen (salvia miltirrhiza) as both contain mild benzodiazepine agonists.

skeletontea
02-23-2006, 09:41 AM
It sounds like that plant may have some very interesting properties. I'm going to look into this, thanks.

hovadagod
02-23-2006, 08:19 PM
Yo JAcky. You should start a pharmaceutical company. Make some new drugs....give those plants to the scientists and tell them to get their asses to work!!

exitwound
02-24-2006, 09:20 AM
Amen to that, Hov!

jacky
02-24-2006, 12:26 PM
pharmacognosy is the study of drugs taken from plants.

hovadagod
02-26-2006, 10:47 AM
That's what I'm saying. That's what you do and talk about.

doctor diesel
02-28-2006, 06:00 AM
Hey Jacky, a bit off-topic perhaps, but while we're talking organic drugs, You the man to answer this.

I've taken to drinking a hot water infusion of ginger and lemon - they sell them in teabags over here. I'm not much into tea but I kinda love this stuff. Anyway, after a couple of cups I've noticed that I feel very pleasant in the head, and that the feeling is very, very similar to being mildly opiated. I figured this must be something to do with the ginger, (let's fact it, it's not the lemon) so I did a Google on 'ginger as a pain killer' and found a couple of references to it having analgesic properties.
So does it stoke up the endorphins, and where can we go with this information?

Doc Diesel

jacky
03-01-2006, 03:40 AM
well dr deisel, I love ginger myself, amazing stuff.

I know ginger contains 1-8 cineole, which is suspected of some sort of analgesic qualities...the oil also occurs in some other medicinal plants. as to 1-8 cineole as a possible opioid I do not know.

ginger is one of the components of the catuama blend. 1 of 4 other herbs, including guarana. this extract blend is purported to be cross tolerant with morphine, now the other herbs like p. olacoides, and t. catigua may have some sort of opioid effect, I do not know, there is no data avialable stating that they are that I know of....so, is this a synergistic effect? or do one or all of these plants contain an opioid active compound? who knows, no one i think.

you and me could work out a simple but maybe fruitless test of this issue,

we can source the herbs seperately, and make a combined extract of half the biomass, then take the other half of the single components, seperately, and in different combinations consume them to try and elucidate any effects leaning to the analgesic. perhaps this would not work well, or maybe it would, the whole extract I have noticed seems to potentiate opioids a bit, and definitely allow for the daily dose of opiates to be lowered without suffering much. so consuming this extract combination and in its seperate equivalents could provide a person with a personal idea of what seems more "analgesic"

ginger is one of the best anti nausea aids I have tried. if I am a little woozy from too much opiates or some other stomach problem ginger usually clears it up.

I eat the root raw sometimes.

1-8 cineole is avialble as a pure compound maybe.

certian species of catnip have an oil which is a purported opiate agonist. I think that MOST of the catnip species have a large amount of this compound in the essential oil fraction. a freind of mine smoked some catnip oil on a cigarette. he claimed it was somewhat relaxing....BUT HE REEKED of the oil for a few hours, and he said he could taste it for a day

exitwound
03-01-2006, 01:29 PM
I have found ginger to be a very useful part of my herb/supplement regimen; it fights inflammation, infection, digestive irritation, and does indeed seem to help directly with pain as well. Not dramatically, but noticeably nonetheless.

jacky
03-01-2006, 02:10 PM
a freind that I work with running the line in a nice little restaraunt burnt himself badly on the hand. he took kratom for the first time that night , which he said helped.
What really helped with the topical pain was a wash of ginger grated in a bit of water and ice, he bathed his hand for 40 minutes or so and the pain was much more tolerable.

reeds ginger soda is great. so is fentimans ginger ferment soda(with cayenne)

cheers

doctor diesel
03-02-2006, 05:55 AM
Thanks for all the information, Jacky - you truly are a font of alkaloid wisdom. I am now going to source myself some ginger root and get chewing. Is it palatable raw? Guess I'll soon find out, although in the UK we also get jars of 'Lazy man's ginger', which is shredded root, possibly part boiled.
1-8 cineole, here we come!

Doc D