loperamide

[ophizzle]

yoplease help my friend took 8 mgs of lopermide and has the cold sweats still feels shitty as hell any help?

[Nuke]

as your attorney I would recommend for him to take more and if that dosent work take even more

[bi11i]

is your friend's name ophizzle?

[1badrabbit]

is your friend's name ophizzle?

LOL TOO FUNNY!!!
Sorry to tell "your friend", but all the lopermide in the world isn't gonna completely relieve your cold sweats from withdrawals. Be careful taking too much as I have heard it has been linked to appendicitis. You need to do some research and make a plan to get through the withdrawals. If you don't learn now your gonna be stuck every time you have to detox. And I can't forsee someone who uses opiates enough to get withdrawals not having to detox at least a couple times.

[lifelong pain]

Ben taking the stuff for 6 years and you won't get high, but it will give you pain relief and will reverse withdrawls from Oxycodone, Hydrocodone and Codeine. You need to take at least 72 mg. Also, I've had various tests and checkups and everything checked out. My liver is fine, no appendix problems either. Basically, the stuff is Meperidine with a modified structure that makes it hard to pass through the BBB (blood Brain Barrier). ANyone who has scientific proof that this is dangerous, let me know. Please, no personal opinions, just the facts!

[lifelong pain]

One last comment. I have been taking RX painkillers for 20 years and my Doc's have told me that with my health problems, I will probabaly have to take them for the rest of my life. Then there is the option of taking 3-6 months off from work and going into a psyciatric ward. I envy those who can get a buzz from drugs. I'm taking Tylenol #4 for pain, Valium for muscle cramps and Adderall for Adult Attention Deficit Disorder and all I feel is normal. Without them i could not hold down a job while providing for my family. Still, it's a burdon. It's a lot of "luggage". If I could go back 20+ years and did things differently, I would. I'm wired for pain and will be for the rest of my life.

[Sykotherapudik Lee]

I have been taking RX painkillers for 20 years and my Doc's have told me that with my health problems, I will probabaly have to take them for the rest of my life. Then there is the option of taking 3-6 months off from work and going into a psyciatric ward.why would you head to the psyc tank?

[jacky]

there are other people that i have heard of using loperamide for withdrawl, some experienced with previous multitudes of withdrawl techniques. One person knew that I would appreciate this structure, as He had just come off of buprenorphine using loperamide. I took the stuff for 6 months or so on an irregular basis. I would feel an energy boost, get the loose mouth that I get when euphoric on opioids etc. I was also taking DXM and codeine and tramadol, poppy seeds, kratom with loperamide. alone the compound probably doesnt lend to euphoria in MOST people. interesting to hear of a chronic pain sufferer who has used loperamide for pain maintenance. I am just not convinced that loperamide doesnt affect brain receptors in some way, or brain tissue in other organs of the body, there are brain tissue deposits OUTSIDE of the brain structure, neurotransmitters etc, there are brain cells in OUR stomach, and loperamide is converted into desmethyloperamide and a few other minor metabolites that maybe have increased ability for the blood brain barrier, I mean this is just conjecture on my part, that and I have percieved some types of effects from taking loperamide on a daily basis, the plasma levels peak some THIRTY hours after taking the compound, so people who take more and more and more in a short span of time searching for quick effects may be taking some sort of risk. people react to opiates in an array of different ways, sick, hallucinating, itching paranoia, etc etc etc. I have seen people who werent the least bit affected by salvinorin a, other people can eat HUGE amounts of opiates. in a paper on the different anomalies of addiction and overdose a person without a tolerance survived a gram and a half dose of heroin that was basically pure as it was a clinical research product! I used chinese dates to reduce the sweats while detoxing, these contain an isoquinoline called nuciferine and other alkaloids that have can relaxing effect. the chinese used chinese dates, corydalis, and dan shen as a sedative /withdrawl reducer. Loperamide should do something for at least the bowel movements! I took loperamide while detoxing off of a good heroin run, and while I was stilll hating it I was able to sleep for a little while, it hurt my stomach, but I hadnt eaten in a day or so, it stopped my diarrhea, this was way before i knew about loperamides stucture, my ex wifes dad wouldnt have bought it for us if he would have known it was an actual opioid! looking back on that situation I didnt take alot, only 8 milligrams or so, I have noticed some much higher doses being taken reported in clinical data and a few personal experience reports.

[lifelong pain]

Actually,
The psych ward would be the only way I could justify taking 3++ months off from work for drug rehab and learning how to cope with chronic pain and ADHD without depending on my meds. I feel quite guilty about all my drug use as I became dangerously addicted to Oxycontin about two years ago. I nearly lost everything, but it's so easy for folks to lecture me on using drugs, but nobody could give me other options to cope with all my physical problems. In fact, I really don't take lectures from the "recovering addicts who's only problem was they were addicted and spent time in jail. I stopped going to NA because there were too many member's "telling me that drugs are my problem and nothing else. Plus, I like the fact that I can hold down an engineering job, spend quality time with my Son and do all the "husband stuff" with my wife. I have depended on Opiates for over twenty years, benzodiazepines for 4 years and Adderall for a little over a year. These Rx's for alf of my life, just like eating, showering and taking Restroom breaks. Not just occasionally, but every day, every hour of my life. Sometimes, when the pain is real bad, I will take my medications around 4:30 in the AM. Right now I'm taking a two week "Adderall Free vacation", since it's not working very well and I'm not sleeping (sleep deprivation is probably the root cause of most of my problems". It's been two days since I weaned myself off the the Adderall (Dextroamphetamine) and every little thing distracts me, I'm eating twice what I did when taking my Adderall. My work productivity is probably down 50%.

[COLONELWAYNE]

Try getting your doctor to scrip ambien for your sleep disorder.It's was a Godsend for me and leaves no hangover whatsoever the next day as most of your diazepams do.10mg.should do wonders just don't plan to go anywhere or do any driving as it knocks me out cold for about 7 or 8 hours 15 to 20 minutes after you take it.You'll wake up refreshed and ready to start your day!It's also good for general withdrawel symptoms too.

[peacefulwarrior]

I think that suggesting ambien to help fill the void caused by another prescription is not the way to go. Ultimately we'll all have to accept that we are reaching for external things to create internal results...going within for these results might be the best way. Meditation is extremely beneficial for withdrawl (excercise too of course.) Regardless of your beliefs, gettin on sleeping pills is just going down the same road on an opposite end from Adderal.

[COLONELWAYNE]

Well, I guess everyone is entitled to their opinion so goes the purpose of these forums.Nonetheless a person who is ADD or ADHD or who is currently taking adderall for any reason,will probably find it almost impossible to sit still long enough to reply to my suggestion much less meditate for any given length of time.I relate to what you are saying,but we sometimes have to learn to crawl again in order to remember we've been walking all along.The ambien was only suggested as a short term steppingstone to getting back into a normal routine.I'm sure all of us would love to be chemical free and lead normal T.V. Land "Leave it to Beaver" " Brady Bunch" family lives, but that's not reality. (though it would be nice for a change in this chemically imbalanced society).I don't know if it's the preservatives in our food or the pollution in our air and water but something has gotten a good number of the worlds population out of touch with reality and dependent on some form of drug just to cope with everyday survival.We are all relying on something external to substitute feelings of happiness we should be producing from within our own bodies without thought or effort (like breathing)What is the solution? I think it's individual trial and error.We try things in our own way and relate what works for us to others.I didn't intend to give a sermon,but I do believe a sleep aide would help this person and ambien is one of the newer more improved less addictive ones on the market.I mean it virtually has no negative side effects for me.I've used it off and on for the last three years and maybe taken a grand total of a 6 month supply.(180 pills) and no I'm not a sales rep for ambien( ha!ha!) just a satisfied patient that has benefited from it's use.

[candy]

Hi all,
I just wanted to stick my two cents in here and I hope no one gets offended, but Loperamide is actually nothing more than Imodium, which is used to treat Diarrhea. It may be helpful for someone in withdrawls who has diarrhea, but causing any pain relief or any other use is really not possible.

Could it be that you are thinking of another drug?
Just wondering, all I could see as possible side-effects in the PDR is a rash and maybe some nausea or stomach pain.
I would suggest it to anyone who is in detox as a way to prevent dehydration, due to the loss of fluids that come with diarrhea.
I am wondering what possible drug could sound like Loperamide?
Well, if anyone has any questions, I have tons of books on Pharmacology and a PDR the Physicians Text Referance, which is great, especially if someone gives you some pill and you have no idea of what it is....The PDR shows pics of each pill manufactured by each company...Great tool and it comes in handy when some dickwad is trying to push some " Great stuff" that turns out to be....Nothing more than some Vitamin supplement...Not that I am that easily suckered. Ya know, I had this friend, who had this friend, who got this stuff.
I wonder if he meant Meperidine?

[Paregoric Kid]

loperamide is in a class of opioids known as phenylpiperidines, which include meperidine, fentanyls, MPTP, ketobemidone, diphenoxylate, and loperamide. if you could get loperamide to cross the bbb you would feel opiate effects and this has been proven in studies.

[candy]

Hey Paregoric Kid,
Sorry to differ with you on this one. Loperamide is an antidiarrheal that works by prolonging gastrointestinal activity. Opium tincture which is a Schedule ll drug drug is often used to control diarrhea, but Loperamide is not a Phenylpiperidine. Those class of drugs are as well Schedule ll and could not be sold over the counter as Loperamide is. Loperamide is also known as Imodium or Imodium A-D.
Schedule ll drugs cannot be sold without a script.
I think as most of us already know, Opiates pretty much slow down the digestive tract.

Phenylpiperidines are such drugs as Fentanyl and Demerol and are Opioid Analgesics, which are Synthetic opiates.
You were right on about the Opioids, but Loperamide is not one of them.
Could you be thinking of another drug that sounds very similar? There are several hundreds of drugs out there with generic or trade names that sometimes sound similiar to other drugs.
I will check some of my Drug Handbooks just to make sure once again.

[candy]

Paregoric Kid,
Well, I will be damned it is an opioid....I can admit when I am wrong. And so be it I am!
So sorry, but hey Humility is something I can do and when I am wrong, there is not point in denying it!
I owe you a big apology!
What I found and I am sure you are aware(as I say this with imbarrassment) is that although it is an opioid, it does not affect the Central Nervous System in the same way as the Opioid Analgesics, therefor it can be sold over the counter.

Once again, So sorry!

I am about to get a bad rep on here!
Goes to show me that us Nurses don't really know it all!
Shame on me!
C.:o

[Paregoric Kid]

no need to apologize, the first time I heard immodium was an opioid I did a double take myself. since that day I've been trying to find a way to abuse it to it's full potential lol

the phenylpiperidene diphenoxylate is also used as an anti-diarrheal. it is combined with atropine and called Lomotil. diphenoxylate does cross the bbb but not effective enough to be used as a painkiller (though some people have said that it creates euphoria without analgesia but that is probably not true). since it can be abused much more so than immodium could be it is schedule 5, though you could get it without a prescription in certain states which allow the otc sale of schedule 5 drugs.

ketobemidone is very odd, it's not even available in the US to my knowledge. I think one reason is because that naloxone/naltrexone are not effective in reversing it's effect, but there is a special antagonist that does reverse it. that could cause real problems because administering naloxone to someone that has overdosed on ketobemidone would be ineffective and in the time it would take to give the proper antagonist they could be dead.

and of course MPTP, the most fucked up phenylpiperidene, causes reversible parkonsins disease

the metabolites of demerol can cause seizures

phenylpiperidines are really strange

[storm]

Does anyone know a way to get loperamide across the BBB in a simple way. I've read research that cereport can be used but who knows where you can get cereport.

[candy]

Paregoric Kid,
Well, thanks for being so great about that! I was really blown away. I thought I did know it all! LOL!!!!
It is a very weird drug and since the recent info, did some more research and learned some new info that will come in handy!
I myself did have seizures once on Demerol, given to me by some quack after he gave me Narcan due to an overdose of Fentanyl(While I was on Methadone!) I was not awake to see it(Obviously) but my Mom said it was about the worst thing she has witnessed. An image she said that will not go away for some time.
Sorta pisses me off that these docs gan administer these meds without knowing drug interactions, complications, side-effects, etc. This doc who gave me the Demerol, knew I was on Methadone, was supposed to have an anesthesiologist present, and was supplied by myself with tons of info on Methadone so that something like what happened would not! WHEW....Long run on sentence there!

Anyway, I am in a great rush and trying to get my thoughts out in one great blow here, but I wanted to respond to your post.
I am always one open to new info and YOU yourself seem to know your stuff. Just reminds me that we are all human!