1mg bupe blocks it all

[warmgun]

Hi,

SWIM always read at @opiophile that the (significant) blocking effect of bupe
would only set in at 2mg+, most stating even higher figures.
SWIM just took 1 (in words: ONE) mg of bupe: total receptor blockage.
Granted SWIM took the done only a couple hours after the bupe but
given that people have effects after 24 hours of ingesting 8 (and more) mgs
of bupe SWIM thought it safe that he at least would have a mild effect off of the done.

So beware: Even .5mg - perhaps even less! of bupe a few hours before and you
might have no effects whatsoever.

SWIM was quite disappointed and also quite upset, given that SWIM himself noted
effects 20h after bupe and having had 4(!)mgs.

SWIM gathers there must be another factor other than half-life which permits the
bupe to work so effective in block the first dozens hours or so.

In retrospect SWIM is rather happy about it - even though it was a waste of $$.
SWIM wonders - given that the done didn't dock on - if he has to wait the usual 2-3 days
til he can take the bupe again.

On another note: There was no buildup of bupe, as this was a an isolated use of bupe.

Well, at least it was only done - and not dope.
SWIM imagines the agony a smurf might feel when smurfing his finest , having paid BIG $$
and then happens: nothing. :mad::p:D

[Saint]

I was on 8 mgs of bupe and it took four days before I felt anything at all of methadone and two weeks before I finally felt pretty ok on done again. So I'm pretty sure buprenorphine blocks very, VERY good...

[Suboxstitute]

Hi,

$$.
SWIM wonders - given that the done didn't dock on - if he has to wait the usual 2-3 days
til he can take the bupe again.


Boy, a one-time dose of 1mg. Actually, it doesn't surprise me. Bupe is some STRONG and variable (by person) shit. I kinda wish I had never started on it.

I would say that as soon as you start to feel w/d symptoms you could dose the bupe again since I believe you are correct - the 'done didn't lock on to the receptors.

BTW - I've been doing a LOT of stuff with spreadsheets and shit, figuring out how long bupe (given a maint dose, not a one-timer like you did) stays in your system. It is UNREAL. I am going to start another stread about it, since I am facing surgery in a few months and would love some opinions about different approaches I am thinking about.

[Black_Pony]

I'm gonna have to call foul about the OP's statement. I've been on bupe 6mg/day for the past 2 days when I shot a bunch of tar last night. I felt WAY better and even somewhat of a rush (although subdued).

I've over came 2 mg/day long term maintenance with big shots of dope MANY times with excellent results.

I will agree that bupe kills the effects of hard earned dope and keeps you from getting as high as you should, but I'm a firm believer that 2 mg is a low enough dose to overcome with a decent shot of dope.

Of course, you took 'done (I don't know how much), so thats a different story.

I'm just saying, I can break through the bupe at low doses like 1-2 mg and I can almost break through at medium-low doses like 6 mg. Its not impossible, you just have to go bigger.

[warmgun]

well, fool is rather more like it.
he plugged the bupe btw , he assumes it's quite a bit more effective than the conventional ROA.
SWIM said he engaged 120mg of done, ie. twice his usual intake.

[Black_Pony]

well, fool is rather more like it.
i'm not sure what thats supposed to mean....

he plugged the bupe btw , he assumes it's quite a bit more effective than the conventional ROA.
SWIM said he engaged 120mg of done, ie. twice his usual intake.

But, 120 mg of done should be enough to overcome the bupe. Should be plenty, I stand corrected. But then again, I've never plugged bupe, my poop shoot is exit-only, thanks. ;)

Plug the fucken 'done and maybe you'll be even. (Then again, I'm sure you did if you plugged the bupe...)

[Saint]

I was on 8 mgs of bupe and it took four days before I felt anything at all of methadone and two weeks before I finally felt pretty ok on done again. So I'm pretty sure buprenorphine blocks very, VERY good...

By the way: I took 20 mgs of done. It might have been differnet if I'd taken 120... but I 'was afraid of OD-ing. So, yes, bupe blocked very well in my case but I switched from 6 to 8 mgs of bupe to about 25 mgs of done..

[roxi*stardust]

Hi,

SWIM always read at @opiophile that the (significant) blocking effect of bupe
would only set in at 2mg+, most stating even higher figures.
SWIM just took 1 (in words: ONE) mg of bupe: total receptor blockage.
Granted SWIM took the done only a couple hours after the bupe but
given that people have effects after 24 hours of ingesting 8 (and more) mgs
of bupe SWIM thought it safe that he at least would have a mild effect off of the done.

So beware: Even .5mg - perhaps even less! of bupe a few hours before and you
might have no effects whatsoever.

SWIM was quite disappointed and also quite upset, given that SWIM himself noted
effects 20h after bupe and having had 4(!)mgs.

SWIM gathers there must be another factor other than half-life which permits the
bupe to work so effective in block the first dozens hours or so.

In retrospect SWIM is rather happy about it - even though it was a waste of $$.
SWIM wonders - given that the done didn't dock on - if he has to wait the usual 2-3 days
til he can take the bupe again.

On another note: There was no buildup of bupe, as this was a an isolated use of bupe.

Well, at least it was only done - and not dope.
SWIM imagines the agony a smurf might feel when smurfing his finest , having paid BIG $$
and then happens: nothing. :mad::p:D


Do you take Bupe on a regualr basis? I have taken up to 4mg and not experienced a FULL receptor block. In fact for a time I was taking 0.125 to 0.25mg along with my meds for potentiation and extended effects.

[mikells43]

dif things happen to dif peopple, this is good to kno tho, it is good to mention to people that are against bupe. thanks for experementing and letting us know.

[EleusisII]

Do you take Bupe on a regualr basis? I have taken up to 4mg and not experienced a FULL receptor block. In fact for a time I was taking 0.125 to 0.25mg along with my meds for potentiation and extended effects.


Did it work?

[roxi*stardust]

dif things happen to dif peopple, this is good to kno tho, it is good to mention to people that are against bupe. thanks for experementing and letting us know.

Did it work?
Yes it does work. It also keeps me from "jonesing" for my pills through the day. Check it out here. We had a few page discussion about it.
http://forum.opiophile.org/showthread.php?t=13450

[chopstix]

well, fool is rather more like it.
he plugged the bupe btw , he assumes it's quite a bit more effective than the conventional ROA.
SWIM said he engaged 120mg of done, ie. twice his usual intake.

I've injected as much as 4mg (usually 2mg), both tex and xone, and then IV'd H within a few hours on multiple occasions without experiencing full blockage; 4mg is very noticeable but 2mg has virtually no blocking effect for me. With suboxone, the Naltrexone in the Suboxone only lasts like and hour so it doesn't really get in the way as long as you wait a bit.

The more I read about people's experience with bup, the more I'm convinced that individual experience is highly subjective and that this is really potent shit.

I wouldn't go as far as to say putting 1mg in your butt blocks it all though.

[Inspektahdek]

8mg is a full dose, 1mg, not quite, I've done 2-4 mgs in the morning and found the scwaggicty by the eve with no problems and nods to no end, I do believe it's personal

[Opiyum]

I'm gonna have to call foul about the OP's statement.

Agreed.

The title of this thread is ridiculous.

People have a habit of blowing things way out of proportion to either impress themselves or others but once again its all bullshit.

I have consistently broken threw 2-6 mgs a day of bupe for the last two years.

Sure it blocks a little bit but is not anywhere as strong as this and many other threads have made it out to be. Methadone, because it is meant to build up in the system and because it is so slow acting probably wouldnt have much of an effect at all. Your talking about a one time 1mg dose though. I don't buy it.

The more days in a row you take bup the more it builds up and the harder it is to get through but after two or three days it levels off. When taking a single dose if you waitied 12 hours it would little to no blocking ability. I realize it varies from person to person but not to that degree.

When on six milligrams a day I used to shoot 40mgs of oxycodone just to break through and then normally 12 hours or so later I was free and clear to use whatever I wanted...eh this is pointless. Forget it.

Have fun with your methadone and bupe just stop giving people the wrong idea. It's irresponsible at the very least.

[deathboy]

It typically takes 4mg for me to experience a blocking effect. Like Roxi I too have used small doses of Bupe to potentiate and extend the shelf life of some opiates. .25mg - .50mg does the trick every time.

DB

[Inspektahdek]

I think it was maybe perhaps the fault of the DOC to break through with, chosen as Methadone, it itself used for w/d and although a full agonist, I do get high from done, it's subtle and I like it alot and it makes me drowsy and at ease when I'm usually high BP and restless. I don't feel buzzed like I do from fent or OC in comparison to the methadone and the fact that maybe 1mg was either just it's effect personally for u to block enough to not feel done, or that it was the methadone.

Today I tried an experiment, I took 1mg of bupe 6-8 hours prior to dosing, and I feel high, there might be a slight block but not even 30% if that and perhaps might not be any blocking at all, the pills haven't even had full time to kick in yet.

I've taken 4mg bupe and broken through with normal dosing and actually nodded out which was hard at that dose prior but it was about 12 hours after bupe dosing, so I'm sure even on maint which might be a little longet but isolated doses will be hard to agree with because I've noticed it doesn't take long to break through at such a low dose of 1mg and personally today being prob my third time I've tried to dose` within 24hrs of bupe dosing and it's worked every time as long as u keep it 4-6mgs and below.~~~ IMOE

[Duckfeet]

That was the wisest thing said in this whole thread, and always left unsaid, for some reason: this stuff isn't just simple mathematics, like some seem to think: it is *highly* subjective, and depends on so many other factors as to be non-sensical.

And to respond to an earlier poster who said something should be posted for those of us who are "against bupe." We aren't "against bupe." Myself, I could give a shit less whether people do bupe or not...what I am *against* is delusional thinking, and I find that *some* who are on bupe, have managed to convince themselves that somehow they have gotten away from the opiate boogie-monster...that they are "clean" and part of their delusion seems to depend on them convincing the rest of us of their wondrous escape from the dope world... *That* I have a problem with, and when I respond to bupe posts, it is only to remind people that they are still doing an opiate, a very *strong* opiate, that not only blocks receptors, but also is in there bods adding to their overall daily opiate intake...and we all know what that means: that means you are seriously strung-out, and to pretend otherwise can bring much heartache, as I--and others--have found. when we finally detoxed, the chickens came home to roost...so to speak ;-)

So take all the bupe you want...but just like they told me on another website: (when i was bragging about having escaped methadone and heroin) that I should wait to claim victory until I'd detoxed off this shit...I thought they were just being mean...but no, they were just trying to prepare me for what was to come....Buprenorphene is a strong opiate, and doesn't give much of a buzz...Those two things often are the problem, and I personally am wary of the stuff....ur mileage may vary...


I've injected as much as 4mg (usually 2mg), both tex and xone, and then IV'd H within a few hours on multiple occasions without experiencing full blockage; 4mg is very noticeable but 2mg has virtually no blocking effect for me. With suboxone, the Naltrexone in the Suboxone only lasts like and hour so it doesn't really get in the way as long as you wait a bit.

The more I read about people's experience with bup, the more I'm convinced that individual experience is highly subjective and that this is really potent shit.

I wouldn't go as far as to say putting 1mg in your butt blocks it all though.

[ZodiacKiller]

I can only post on what I myself have experienced; one morning a while back when I was on much higher doses of of Bupe, I did my morning 8mg dose, and later that evening (about 10 hours after taking that 8mg), I unexpectedly came across a quantity of heroin. Didn't plan it---copped for a friend, and, well, you know how that goes.....

So: split a gram with the wife, not expecting much, but knowing that my guy's dope is always really good, so I hoped for at least a small amount of euphoria.

Well, that smack blasted through the bupe like a panzer through Poland. Completely fucked up, nodding, the whole nine yards...

Don't believe the hype----but it can be a dangerous, double-edged sword, switching back and forth. Believe me, I know, and feel free to PM for horror stories if ya want.....:mad:



ZK

[scarlettt]

I started at 12 mg, and I've slowly weened (<--- does anyone but me even say that word?) down to 1 mg. per day.

Since going down to 1 from 2, I've definately noticed a difference. Chills, stiff muscles, stuff like that. (So much so that last night I said fuck it and took 8 mg, cuz I was sick of it)

Anyways, at 2 mg. ... it was blocking all that. Even though the symptoms I've had since lowering to 1 are mild in comparison to what they could be... it's making me extremely nervous at the thought of making the final jump.

[deathboy]

I wouldn't jump until I stabilized on .25mg at a minimum. I attempted to jump at 1mg and was hating life.

DB

[chopstix]

I wouldn't jump until I stabilized on .25mg at a minimum. I attempted to jump at 1mg and was hating life.

DB

x2, and stabalized being the key word.

Bup is 100-150x stronger than morphine, even .25mg is like jumping at a half grain of morphine and although not huge, that's still enough dope to make you miserable for awhile...

[jonny-5]

ya, its really potent at lower doses, so ive found. this is why this time around im gonna keep my dose below 1mg the whole time. it has (for me) the same agonistic effects at this low of a dose, and i see no reason to go any higher. plus when it comes time to jump off, hopefully the wds will be much less.

[rizzo]

i can take 8 mg of bupe in the morning,say around 9,later in the day around 7 or 8 ill do a shot,a big shot i mind you,but ill get pretty fucked up,really good rush,then my buzz doesent last as long as it would if i hadent taken the bupe,but i get high still/