REMOxy wow all opiates will be made this way omg

[pun1178]

REMOXY™
Remoxy is a novel, abuse-resistant form of twice-daily oxycodone, currently in a Phase III clinical trial (http://phx.corporate-ir.net/phoenix.zhtml?c=120834&p=irol-newsArticle&ID=817867&highlight=).
Remoxy is intended to meet the needs of physicians who appropriately prescribe opioid painkillers and who seek to minimize risks of drug diversion, abuse or accidental patient misuse. Remoxy resists injection or snorting. Published data also show that freezing, crushing or submerging Remoxy in high-proof alcohol for hours at a time releases just a fraction of oxycodone at time points when abusers presumably expect to get high. These properties of Remoxy may deter recreational abuse or accidental patient misuse of long acting oxycodone.
In November 2005, we entered into a $400M strategic alliance with King Pharmaceuticals, Inc. (NYSE: KG) to develop and commercialize Remoxy and three other abuse-resistant opioid painkillers. Terms included an upfront payment fee of $150M cash, $150M in clinical and regulatory milestones and $100M in research and development expenses. Additionally, King will record net sales of all products and pay Pain Therapeutics a 20% royalty, except for the first $1 billion in cumulative net sales, which royalty is set at 15%.


MY pharmcy friend who is still in college says in the next 3 years all tablet opiods will be 99.8 % abuse proof god shot me

[resorcinol]

Heroin and pods will see a surge in popularity if that happens.

Also... I bet it won't be as effective for pain despite what they claim. Pain patients will protest if that's the case.

[tptptp]

There's always a way around the stuff. I'd bet junkys will find a way around it without any money if they spent 450 trillion on it. Besides, they need recreational users to make their profits fat. They just do a little publicity and ass kissing, that's all.

[hydrocodonious]

Very interesting.....take a look at this site for more information.

http://www.durect.com/wt/durect/page_name/remoxy

ALSO, look at there Sufentanil patch that lasts for 7 days instead of only 3!

ALSO, look at there CHRONOGESIC when, " Once implanted, CHRONOGESIC is designed to deliver sufentanil for period of up to three months from a single application. "

*quote from website*

Looks like youll just have to take a bunch orally...doesnt sound too bad. Even though im trying to be clean right now ill have to stockpile some Oxys.

http://money.cnn.com/2007/01/19/news/companies/durect/index.htm

"[Remoxy] can't be crushed up and snorted because it's a gel cap," said Durect Chief Executive James Brown. The CEO also said that the Remoxy loses potency when combined with alcohol, unlike other painkillers, which gain potency when added to alcohol, with dangerous and sometimes fatal results.
*from the neother link*

This actually sounds pretty interesting....

[tptptp]

i got a few pods still dont kno how to make them blam

There's a section devoted to pods and a section for pharms...you wont get much of an answer by posting in an unrelated thread in the wrong forum

[Hiram]

REMOXY™
Remoxy is a novel, abuse-resistant form of twice-daily oxycodone, currently in a Phase III clinical trial (http://phx.corporate-ir.net/phoenix.zhtml?c=120834&p=irol-newsArticle&ID=817867&highlight=).
Remoxy is intended to meet the needs of physicians who appropriately prescribe opioid painkillers and who seek to minimize risks of drug diversion, abuse or accidental patient misuse. Remoxy resists injection or snorting. Published data also show that freezing, crushing or submerging Remoxy in high-proof alcohol for hours at a time releases just a fraction of oxycodone at time points when abusers presumably expect to get high. These properties of Remoxy may deter recreational abuse or accidental patient misuse of long acting oxycodone.
In November 2005, we entered into a $400M strategic alliance with King Pharmaceuticals, Inc. (NYSE: KG) to develop and commercialize Remoxy and three other abuse-resistant opioid painkillers. Terms included an upfront payment fee of $150M cash, $150M in clinical and regulatory milestones and $100M in research and development expenses. Additionally, King will record net sales of all products and pay Pain Therapeutics a 20% royalty, except for the first $1 billion in cumulative net sales, which royalty is set at 15%.


MY pharmcy friend who is still in college says in the next 3 years all tablet opiods will be 99.8 % abuse proof god shot me

Regardless of the claim, I don't believe for a second that junkies won't find a way around any method to try to deter recreational use. All that money wasted on R&D, and with a little effort and basic chemistry the abuse mechanism will most likely be broken. You can't keep an opiate addict from their goods, who are they trying to fool?

[Sneaky]

if your stomach can find a way inside the pill, then junkies will find a way inside the pill as well


spending this much money to develop a pill that simply stops people from getting high? god damn, is this seriously what everything has come to? this is fucking pathetic in my opinion, they're basically trying to protect people from themselves now

[tptptp]

they're basically trying to protect people from themselves now

Nah it's all marketing and asskissing publicity BS they need illegal users to keep their pockets fat and that's the only thing they care about. On the governments side if they really wanted to "protect us" alcohol and cigs would be illegal too. This is supposed to be America though....you know where the founders fought tremendous odds to gain freedom for themselves and for their future generations. GOT to stop letting the government take our rights before this becomes a broke, communist country.

[GoddessofRATs]

Some street pharmacist/scientist or junkie will find away around it. I don't like where the future of Opiate Pain Medication is going LOL. And like Resorcinol said, there will be a rise in pods and probably seeds, which won't be good either, eventually they'll find a way to take that precious resource from us as well.

That whole thing makes me so mad LOL. Everytime we get something good that we can get high from and helps with pain it's taken away from us. I wish there was a country or some new Island where all opiates were legal and you don't need a prescription for anything. Or even a planet that is run by an Opiate-friendly government that we can all migrate over to LOL

Ok that must be the poppy seed high talking. sorry. Hey, a girl can dream, can't she?

GOR

[Dr. Oxy]

Idk you guys are placing a lot of faith in our junkie inginuity, but if its too expensive or hard to do, we'll eventually lose interest. Their SABER(whats in the gel cap) system gel is a step up from Opana's gel matrix, and none of us have broken that yet.

http://www.durect.com/pdf/SABER_FINAL_06.pdf

[roxi*stardust]

Yeah someone posted a link about this about a year ago. Oxycontin and Roxicodone will still be around and RX'd by doctors. New drugs like this are always EXTREMELY expensive so most insurnace won't cover it and people who pay cash won't be able to afford it so doctors will continue to write for OC's and Roxi's. Not worried about it.

[Slippin|Fallen]

Heroin and pods will see a surge in popularity if that happens.

Also... I bet it won't be as effective for pain despite what they claim. Pain patients will protest if that's the case.




agreed, or people will simply just 'EAT' more of them to get high.

[Ale]

this is fucking pathetic in my opinion, they're basically trying to protect people from themselves now
What you mean NOW?Ain't that the way they've always gone through?What's new?

Yeah someone posted a link about this about a year ago. Oxycontin and Roxicodone will still be around and RX'd by doctors. New drugs like this are always EXTREMELY expensive so most insurnace won't cover it and people who pay cash won't be able to afford it so doctors will continue to write for OC's and Roxi's.
LOL That's exactly what I was thinking.I won't add a word:)

[tptptp]

Our government deals drugs themselves, not worried about it.

[pharmboy]

We are addicted to opiates, our government is addicted to money. Our

government gets their fix by trying to denie us of ours. But also I think

alot of it comes down to people like the DEA just hate the idea of euphoria,

they don't want anybody to be less misrable than them. Sick Fucks. .:jumping-s

[Thebane]

I've never used time release opiates so this may be completely off base, but why couldn't you just eat a couple and get high for 10 hours? Rather than break the time-release of one and get high for a few?

[hydrocodonious]

I've never used time release opiates so this may be completely off base, but why couldn't you just eat a couple and get high for 10 hours? Rather than break the time-release of one and get high for a few?

This is exactly what im thinking. Plus they are gonna be a gel cap so they will look coooooler. I kinda like they idea that its resistant to dissolving in alcohol. This is going to save a lot of lives from people mixing there oxy with beer/liquor who are opiate naive.

[DCBA]

If it's a gelcap maybe it can be smoked like fent patches, alltought i never tried fent, i only wish i could..

[roxi*stardust]

Yeah someone posted a link about this about a year ago. Oxycontin and Roxicodone will still be around and RX'd by doctors. New drugs like this are always EXTREMELY expensive so most insurnace won't cover it and people who pay cash won't be able to afford it so doctors will continue to write for OC's and Roxi's. Not worried about it.

[aj11]

you'd think with this new device more people would OD trying to get high by taking more pills than they should
my 2 cents

[Levity]

Idk you guys are placing a lot of faith in our junkie inginuity, but if its too expensive or hard to do, we'll eventually lose interest. Their SABER(whats in the gel cap) system gel is a step up from Opana's gel matrix, and none of us have broken that yet.

http://www.durect.com/pdf/SABER_FINAL_06.pdf

Opana has been broken.

Treat it just like a Teva and all the goodies gets released into the warm liquid.

Not so go for shooters, but...

[Dr. Oxy]

Opana has been broken.

Treat it just like a Teva and all the goodies gets released into the warm liquid.

Not so go for shooters, but...

Well thats what I mean, everybody hates Tevas anyway, what are you talking about? You may get some of the oxymorphone out but not a majority, and snorting, and swallowing suck.

[OPticrazi]

As it relates to the "anti abuse" efforts, even my PM doc says that manufactures of opiates, like Teva are producing "a less effective product". The insurance companies force individuals to use these products by making the cost prohibitive, instead of the effectiveness of the drug. So there is a lot of blame to spread around if you ask me!
I'm one of the fortunate people who has a PM that is not a dick! He writes my scripts for brand and leaves the decision to me. As it should be!

[JonnyMohawk]

i got a few pods still dont kno how to make them blam

Seriously, as a lesson, hijacking a thread like that is not cool. UTFSE ('Use the Motherfucking Search Engine')

You will find your answer there without even having to steal or create a thread.

[bronyraur]

Seriously, as a lesson, hijacking a thread like that is not cool. UTFSE ('Use the Motherfucking Search Engine')

You will find your answer there without even having to steal or create a thread.

I took care of it and deleted his post.

[h.john]

its made from gelitin the gel is, and to my luck I am allergic to gelatin, even have it written in my records lol.
so looks like i will have to have normal stuff, but i take my meds as directed anyway so its no big deal for me.
I think also for people like me (chronic pain sufferer) and also the cancer patients, will get this medication prescribed with less fear that it cant be used in the wrong ways, so I think this is a great step,the ppl that need it might get medicated correctly since fear will drop, docotrs will be more relaxed, as they dont need to worry about the patient as much this is a big step forward to help combat the drug abuse problem, and to help the pain sufferers, a win for US

[Mcdom]

I just can't see why euphoria via opiate use is such a SIN!

[nick]

I just can't see why euphoria via opiate use is such a SIN!

Blame Max Weber.

[Duckfeet]

I've always said it: u r one bright cookie, Nick: and I've been trying to plow thru pieces on one of his texts again, as between that, and this other book I read: Narcissim i America, or something like that, they sum up what the fuck happened here..but Weber was able to show just how heavy the old protestant ethic was, tho we never admit...but all I got to do is look at the White House...and tell me it's still not alive and kicking...


Blame Max Weber.

[Mcdom]

Yes - blame Max Weber and his ilk.

I have Narcissim in America - I am an avid reader - especially on this topic.

That ethic is flourishing - they don't want to call it SIN - but that's part of the origin of this mindset.

Sin and rehab as redemption.