Unscheduled and (AFAIK) untested Depressants

[Hammilton]

For the past few days I've been pouring over barb, benzo and pseudo-barb depressant SARs and looking at the most enjoyable of the bunch. Unless the drug is a strict benzo or barb, though, there's not a whole lot of study been done on a lot of this stuff that I've come across.

So, that said, here's an image of two drugs I assume will be active, be at least as enjoyable as benzos and shouldn't be scheduled according to my understanding of the US analogue act. In the UK and other countries, they'll be completely legal as best I can tell.

http://www.imagehosting.com/out.php/i1298616_GoodLookingDepressants.bmp

http://www.imagehosting.com/show.php/1298616_GoodLookingDepressants.bmp.htmlhttp://forum.opiophile.org/%5BIMG%5Dhttp://www.imagehosting.com/out.php/t1298616_GoodLookingDepressants.bmp.jpg%5B/IMG%5D%5B/URL%5D

[Nate]

hmm i can only wonder :rolleyes: so many questions lol.

[Hammilton]

what are these questions? I can do my best to answer them until someone with a brain comes around.

[Nate]

My questions would go towards the effects, euphoria ect. Also effectiveness of reducing anxiety (other common purposes for benzos and barbs.) Im sure that would be difficult to answer seeing as you havent tried them :P

That why i said i wonder (inmagination flying around the room)

[Hammilton]

Yeah, without having tasted them, it's difficult to say with absolute certainty, but these barbs and benzo's are among the most widely studied classes of drugs in the world, probably second and third only to opiates, and that's no guarantee.

The nitrogens are in the wrong places for them to really be considered 'barbituric acid derivatives' (barbs would have the nitrogens on opposite sides of the double bonded oxygen), and no true barbs have any extra rings.

I like the extra rings because they're what, in all likelihood, decreases the respiratory depression caused by barbs.

THis is probably a little confusing because I'm using the word 'barb' for two distinct things. All barbs have 2 nitrogens, and the double bonded oxygen in between them, and no double bonds on the cyclohexane ring, but on both of these I used the (differently located) 2-nitrogens, double-bonded oxygen and a cyclohexene ring instead of the cyclohexane- a la methaqualone, not the true barbs.

Look up the structure of methyprylon, methaqualone, secobarbital and diazepam and you should quickly see the similarities.

I kinda wonder if replacing the furan ring on the above with a methylenedioxy ring would be better, I'm not sure. Methaqualone isn't a true entactogen, I suppose, but it certainly shares some similarities, which I assume is because of the extra benzene ring and not the phenyl group. But then again, I'm more used to looking at phenethylamines- and I'm fairly certain that the rules for an 'entactogenic depressant' are way different.

Still, I'd suppose the barbabenzo would be active between 5 and 30mg, but no idea on the more quaalude-esque furan-for-benzene substitution will do.

This sort of thing would be vastly different from any of the compounds I pulled up on Substructure search (a great tool, btw), so who knows.

EDIT: sorry, just noticed that an having a methylenedioxy group would make compound #2 look kinda similar to an odd MDMA analogue, just that wasn't. I wonder if the phenyl group where it is makes methaqualone as good as it does- it fits with a sort of PEA-type drug, but with a cyclohexene instead of the benzene.

[drugsaregood]

*Licks the images*. I think your wrong man, I don't feel nothin.