Bupe vs. Pain

[earthenone]

If you are on bupe, and you break your leg or something like that, or just suffer from chronic pain, what happens if you really need narcotic painkillers? From what ive read they wont work, that would suck really bad, could they inject you with enough morphine to break over and kill your pain? Just wandering.

[exitwound]

It's not the bupe itself that has the blocking action....it's the naltrexone/naloxone that's included in the mixture known as Suboxone! Plain ol' subutex, which is straight bupe, has no real blocking action AFAIK.

[earthenone]

So theoretically one could get on plain old subutex, and still be on a pain regimen? Just wondering, say a guy took normally way too much pain medicine due to tollerance if he could get on subutex and get back down to a normal amount?

[ironminde]

It's not the bupe itself that has the blocking action....it's the naltrexone/naloxone that's included in the mixture known as Suboxone! Plain ol' subutex, which is straight bupe, has no real blocking action AFAIK.
You are incorrect, sorry.

Bupe DOES block the action of other narcotics, and the reason being is that it has a higher affinity for the receptors, thus preventing anything else from binding to them and allowing them to exert their effects.

Naltrexone has poor bioavailability taken orally, so the Naltrexone in the Suboxone doesnt have any effect. It is put in there to prevent IV'ing the pills, since IV'd the Naltrexone would then work and induce WD's.

Subutex does not have any Naltrexone in it, it is just Buprenorphine.

Hope that helps.

[ironminde]

So theoretically one could get on plain old subutex, and still be on a pain regimen?

Well, depending on the dosage/ blood levels of the bupe.

Just wondering, say a guy took normally way too much pain medicine due to tollerance if he could get on subutex and get back down to a normal amount?

I have read of others who have tried doing this.. using an antagonist to try to lower tolerance, but i dont believe they had much luck. I dont have any personal experience with this, sorry.

[exitwound]

You are incorrect, sorry.

Bupe DOES block the action of other narcotics, and the reason being is that it has a higher affinity for the receptors, thus preventing anything else from binding to them, thus allowing them to exert their effects.

Naltrexone has poor bioavailability taken orally, so the Naltrexone in the Suboxone doesnt have any effect. It is put in there to prevent IV'ing the pills, since IV'd the Naltrexone would then work and induce WD's.

Subutex does not have any Naltrexone in it, it is just Buprenorphine.

Hope that helps.

Makes sense.....I stand corrected!

[shaunclo]

I need to correct the info here, there is no naltrexone in suboxone, only naloxone. But everything else was correct.

[earthenone]

Although it was kind of a question of lowering tollerance, it was kind of a question of changing a cycle, like when chronic pain keeps you from kicking, and one is stuck in a cycle of 3 weeks of t. and quitting t for a week to go on pain meds, the whole months supply, then seeing pain management dr., and repeating cycle. Especially if one was just told that the pain level would probably never go down, and he had to "learn to live with it, you know those old people who walk around hunched over, they live with the pain of multiple fractures in their backs" It wouldnt be so bad if one werent under 30, oh well i guess i know what lies ahead of me now.

[psychotiKK]

No one really even answered his question.. What can a suboxone user do if they are in serious need of medical attention? (obviously need strong painkillers to do this) Just give you really high levels of morphine or hydromorphone? That has always worried me, because I don't want to be fucked and have nothing work with me for pain.