Fencamfamine: Another Stimulant w/ Opioid Activity

[Paregoric Kid]

this one looks interesting like lefetamine but I don't think it works as strongly on the opioid receptors as lefetamine; still very interesting!
http://en.wikipedia.org/wiki/Fencamfamine

Reinforcing properties of fencamfamine: involvement of dopamine and opioid receptors.
Fencamfamine (FCF) is a psychostimulant classified as an indirect dopamine agonist. The conditioning place preference (CPP) paradigm was used to investigate the reinforcing properties of FCF. After initial preferences had been determined, animals were conditioned with FCF (1.75, 3.5, or 7.0 mg/kg; IP). Only at the dose of 3.5 mg/kg FCF produced a significant place preference. Pretreatment with SCH23390 (0.05 mg/kg; SC) or naloxone (1.0 mg/kg; SC) 10 min before FCF (3.5 mg/kg, IP) blocked both FCF-induced hyperactivity and CPP. Pretreatment with metoclopramide (10.0 mg/kg; IP) or pimozide (1.0 mg/kg, IP), respectively, 30 min or 4 h before FCF (3.5 mg/kg; IP), which blocked the FCF-induced locomotor activity, failed to influence place conditioning produced by FCF. In conclusion, the present study suggests that dopamine D1 and opioid receptors are related to FCF reinforcing effect, while dopamine D2 subtype receptor was ineffective in modifying FCF-induced CPP.

[Hammilton]

It's pretty weak in terms of any opioid effects. Actually, I can't feel any opioid effects at all on it- and the only 3 times I ever had it I had 0 opioid tolerance (10mg of hydrocodone was great back then).

[Paregoric Kid]

yeah it is not lefetamine but it's stimulant and reinforcing effects occur at the opioid receptors, it can be reversed with naloxone.

[Hammilton]

It's an indirect dopamine agonist like amphetamine, so I don't think the reinforcing effects are blocked by naloxone, since that's not mentioned as being true (at least in what I've read).

Still, I'd take Oxy or even amphetamine over fencamfamine anyday.