Morphine Nasal Spray

[I-Nod]

After running out of pods and money a very generous person gave me their morphine script (because they're allergic.) They also have a 90 day refill coming, which they will give me also. Now I didn't particularly care for the morphine high at all, but the best buzz is a free one, so my quest began...

Well after taking by mouth, that obviously sucked. So I snorted a couple. That worked ok, but nothing to write home about. Lastly, being a true junky... I plugged the shit! (And yes, I used the advanced princess-manicure position WITH the leg up!)

Snorting was decent, but the constant repeating of this procedure packs a ton of powder up the ole snoot. It's also a pain in the ass getting all those time-release coatings out of the powder. Now, plugging worked very well, but I'm not too fond of the whole ritual. And quite frankly, I felt pretty disturbed during and after the routine. So I started thinking, and remembered the advice of some of the great ones on Ophile... and ended up making my own morphine nasal spray.

I took some photos of the process also... it's not something that really needs How-To photos, but I'm feeling good and don't give a shit. (Hence my confession in the above paragraph.) But I did find this nasal spray to hit much faster and harder than snorting powder or plugging did w/ the same dosages. Maybe it's just me, but I'm definitely a fan. I also like the fact that you can make several days worth and it can be carried around easily. You can also use it anywhere you like... in front of your ma, in line at the grocery store, at church... try plugging in church sometime - it's impossible w/ the damn pews so close together!

So, ok, this was my first time and just a test batch, so I started out emptying 6 Kadians into my makeshift mortar and pestle dish (Pic 1). Then proceeded to pulverize the beads w/ my high-tech screwdriver-pestle (Pic 2.) Then I boiled some water in the microwave and quickly added 3mL of water to the powder. I debated on using saline, but wasn't sure if that was such a great idea (Pic 3.) I let this mixture set for about 1 to 2 hrs, then took my syringe-like thingy (it's a syringe they give you in those printer-ink refill kits) and sucked up the cloudy liquid (Pic 4.) The next photo is a close-up of the nasal spray bottle I used... I liked how they show you how much liquid is expelled w/ each spray... this made the dosing math much, much easier. I also liked how the spray bottle just screws off, so refilling is very simple.

Welp, that's about it. I found the spray much easier on the ole beak too. Whereas before I was putting a LOT of powder up there, now just a couple squirts, and it seems to coat a lot more surface area also. Ok, hope ya enjoyed, peas and love to all!!

[I-Nod]

Here's the rest of the pix... sorry if this was a retarded or repeated thread. :D

[johnysmoke]

I share you love of the spray bottles as well. That is a really great idea. Killer pics as well. I'm sure it tastes pretty bad but that taste will go away when the warm and fuzzy feeling comes along with all of it's greatness. I do the same thing with fentanyl patches, the kind with the gel. I love being able to walk around anywhere and take a few sprays to get a good ringer and nobody knows what the hell you are doing. Plus it makes those patches last a hell of a lot longer and they hit you way harder.

[xecutrex]

Hey man, you did remember to wash your hands after you plugged it right? Your finger in the 3rd pick is looking a little funky. :D

Nice guide and pics btw, like it.

[GOLD N DIEMONDS]

Hey man, you did remember to wash your hands after you plugged it right? Your finger in the 3rd pick is looking a little funky. :D

Nice guide and pics btw, like it.

MMMMMMMMMMMM -LMAO

[I-Nod]

Hey man, you did remember to wash your hands after you plugged it right? Your finger in the 3rd pick is looking a little funky. :D

Nice guide and pics btw, like it.

Ahahaa, that is pretty funny!!! I seen that and was ready to crop it out, but said Fuck It! Actually, that is from smoking "roll your own" cigarettes. I'm broke as a joke and can't afford $4 packs, so I buy TOP and roll 'em up. The only down fall, besides not having a friggin filter, is that your fingers turn orange. (Would hate to see my lungs!)

Eh, sucks for me, but that's the kind of shit ya gotta do when you have kids. (That's a warning to all you 20-something guys out there!! If you wanna party, have money and play around... wear your "boots" to bed!!! :D ) I'm playing, I'd have it no other way!!

[Inspektahdek]

I share you love of the spray bottles as well. That is a really great idea. Killer pics as well. I'm sure it tastes pretty bad but that taste will go away when the warm and fuzzy feeling comes along with all of it's greatness. I do the same thing with fentanyl patches, the kind with the gel. I love being able to walk around anywhere and take a few sprays to get a good ringer and nobody knows what the hell you are doing. Plus it makes those patches last a hell of a lot longer and they hit you way harder.


can you explain your process of using the fentanyl gel into nosespray bottles? I am very intrigued by this and would like to try myself

[Somanax]

I personally really like

the home made

mortar and pestle

great idea on both count's

and I got orange finger's too:o

[xecutrex]

Ahahaa, that is pretty funny!!! I seen that and was ready to crop it out, but said Fuck It! Actually, that is from smoking "roll your own" cigarettes. I'm broke as a joke and can't afford $4 packs, so I buy TOP and roll 'em up. The only down fall, besides not having a friggin filter, is that your fingers turn orange. (Would hate to see my lungs!)

Eh, sucks for me, but that's the kind of shit ya gotta do when you have kids. (That's a warning to all you 20-something guys out there!! If you wanna party, have money and play around... wear your "boots" to bed!!! :D ) I'm playing, I'd have it no other way!!

Ah, so is that the rolling tabacco next to the pan? or is that some grinded up bud. Im gunna have to try that roll your own shit though, cig prices are killing me.

[I-Nod]

I personally really like

the home made

mortar and pestle

great idea on both count's

and I got orange finger's too:o

Thanks Mr. Somanax! And if you ever find something, short of sand-blasting, that gets the stains off, let me know :D

Ah, so is that the rolling tabacco next to the pan? or is that some grinded up bud. Im gunna have to try that roll your own shit though, cig prices are killing me.

Nope, that isn't tobacco or schwag... it's just a cheap shelf and the fake-wood laminate peeled off. If you set too many cold beers on that cheap shit, they tend to bubble up, then peel off. Anymore, unless you go to an expensive furniture shop... everything is made of that crappy pressed-sawdust! No wonder antiques are so expensive. :D

As far as cigarettes go, see if you have a "Cheap Tobacco" store near you. After you buy this $10 rolling contraption, you can get tabacco(120+ cigs) and filter-tubes(cartons worth, 200 count) for $9 bucks. I basically pay about $12 for a carton... I'm trying like hell to quit though *hack cough cough spit* ughh...

[I-Nod]

Hmm... well... I duly apologize for my inaccurate, or uninformed rather, info here. Upon further research of Morphine bio-availability, insuffilated Morphine has the worst bio of all ROA's.

Orally tends to be around the 30% mark, give or take, compared to IV which is 100%. However, nasally is reported to be only 10% respectively. And rectally, a favorite here at Ophile ;), seems to be around 60%.

BUTT!!! I did happen upon a very interesting article: http://jpet.aspetjournals.org/cgi/content/abstract/301/1/391

It states that adding Chitosan to the nasal-spray increases the bio-availability, bringing it up to the 60% mark!! So I will try to obtain some Chitosan (please don't tell me this is illegal now!!!) and test this hypothesis. It will probably be a good week before I will try this, but I will definitely report back any findings.

I would so much rather snort some spray through-out the day, than stick shit up my arse! I really hope this pans out. Welp, until then, apologies from the plugger :(:(:(

[Slippin|Fallen]

Here's the rest of the pix... sorry if this was a retarded or repeated thread. :D


This post is very sloppy, I am sorry for that. Its late, I am tired and nodding!


Forgive my lack of knowledge. Im guessing the little chunks are the time coating? So basically you crush it up not to a fine powder but to kind of little chunks put some water in (brain fart did you say cold hot warm?) let it sit, and in the bottom you had your liquid substance and the chunks were the time release stuff?

also found this...

"However, chitosan is able to significantly bind with fat molecules and convert them into a form which the human body does not absorb"

that doesnt sound good. although i am not chemically inclined anymore (since middle school actually, how sad).

I think I am aloud to post links, if not im sorry and feel free to take out!

http://www.vanderbilt.edu/AnS/psychology/health_psychology/chitosan.htm

------------------------------------------------------

I also found this per google-
Salts of opioid analgesics, particularly morphine, and methods of ... (http://www.freepatentsonline.com/6387917.html)

More recently, the delivery of morphine via the nasal route in the form of a nasal .... of chitosan using chitosanase or by the addition of nitrous acid. ...
www.freepatentsonline.com/6387917.html (http://www.freepatentsonline.com/6387917.html) - 36k - Cached (http://64.233.169.104/search?q=cache:8VciT17_ouAJ:www.freepatentsonline. com/6387917.html+using+Chitosan+in+nasal+spray&hl=en&ct=clnk&cd=4&gl=us) - Similar pages (http://www.google.com/search?hl=en&q=related:www.freepatentsonline.com/6387917.html)

http://www.freepatentsonline.com/6387917.html

[I-Nod]

Yeah, the Kadians have a bunch of little white balls inside of the capsule. Each ball is covered w/ this wax-like coating which is the time-release mechanism. After crushing them up, these wax coverings stay fairly intact, although they are split open.

I left them in, and even did a quick re-wash. After you suck the liquid out, I imagine the morphine coats all the wax capsules as the water slowly lowers in the bowl.

I'll have to read up on chitosan... I just found it earlier and haven't had time to check it out. From the excerpt you posted, it kind of didn't make sense to me (I'm pretty high myself :D) But from what I gathered, chitosan is used as a diet agent... so maybe this affinity it has for fat cells is why it's used as a diet aid??? Eh, who knows... But appreciate the find man!! I'll definitely look into it further. Hell, anything that'll increase the bioavailability of morphine, and could possibly keep foreign objects outta my ass!! :D

[bronyraur]

Nice how-to write-up, I-Nod. Hope you have more success increasing the effectiveness of your homemade morph nasal spray.

[rachamim18]

The original poster is correct in saying the bioavailability is 10%, actually 10 to 15% but fair enough., He/she is alos correct about Chitosan but it remains an unkown quitent.

Chitosan is prepared from chitan. Chitan is a substyance found in the shells of certain red colored shrimp. It is used in the form of Chitosan as a dietary aid for people with high cholesterol,etc. Trials have shown the combination of morphine compounded with Chitosan has resulted in bioavailabilty of well over 50% (some stated as high as 80%!) when insufflated (snorted).

The main problem with this is that there is no way to gauge effective compoounding. Ratios are still unquantified,etc. Another problem is thqat in all studies I have examined, they were suing Chitosan as a liquid and I have not been able to find a pure Chitosan in liquid form.

Plugging also, sadly, has a very low bioavailability.

[kyuss]

The original poster is correct in saying the bioavailability is 10%, actually 10 to 15% but fair enough., He/she is alos correct about Chitosan but it remains an unkown quitent.

Chitosan is prepared from chitan. Chitan is a substyance found in the shells of certain red colored shrimp. It is used in the form of Chitosan as a dietary aid for people with high cholesterol,etc. Trials have shown the combination of morphine compounded with Chitosan has resulted in bioavailabilty of well over 50% (some stated as high as 80%!) when insufflated (snorted).

The main problem with this is that there is no way to gauge effective compoounding. Ratios are still unquantified,etc. Another problem is thqat in all studies I have examined, they were suing Chitosan as a liquid and I have not been able to find a pure Chitosan in liquid form.

Plugging also, sadly, has a very low bioavailability.

I'm going to look
into this Chitosan.
From 10 to 50
would be excellent.

Great thread I-Nod
Love the pics

[EleusisII]

Seems to me, you need to construct some sort of nasal-butt spray...

[Synack]

Seems to me, you need to construct some sort of nasal-butt spray...

butt plug auto sprayer 5000.... sprays you every 2 minutes, and each time you sit down.



damn, you junkies is some sick pups


j/k.

-Me on methadone having a bad time for the past few months... now wheres my prozac

[I-Nod]

Seems to me, you need to construct some sort of nasal-butt spray...

How would this work? You pull it out of your ass, then stick it in your nose? Nasal-butt spray - 3 words that should never be in the same sentence!

Nah, I know what you meant... I like Synacks idea!! Every time you sit down, haha. Would hate to be at the back of the bus on a bumpy ride though! Another butt-spray overdose in the pot-hole riddled suburbs of Cleveland...

[CIIORNOTHING]

If you are going to bother with morphine, at a minimum you need to sub-q (skin pop) it. Best is IV, but IM or subq works too.

Anything other than that you are simply wasting about 70% of the drug if not more....

[Duckfeet]

Yeah, my heart lifted when I saw the "plug finger" too...we creep around in darkness, but crave the light of day...I dealt with these hardassed pills myself, and of course, was slightly sick and impatient, and was "popping" them onto the floor, trying to crush'em w/the back of me trusty ol Buck knife...*bad* move...shit, trying to find them fuckers when they're scattered..and even after it was all done, and I IVed'em, I found after the quck rush, that they weren't that good, IMO...prefer dilaudids any day....I've never plugged'em tho, but Rach makes even that noble activity seem hopeless :-(

[I-Nod]

If you are going to bother with morphine, at a minimum you need to sub-q (skin pop) it. Best is IV, but IM or subq works too.

Anything other than that you are simply wasting about 70% of the drug if not more....

I full-heartedly agree, CII. However, I personally don't want to pick up the needle just yet. I have many years of opiate addiction ahead of me, so I have to drag my feet as much as possible if I intend to reach a ripe ole opiated age.

Although, for me, the nasal spray was much better than oral or rectal administration, I corrected my original post to help snuff out mis-information that I had unintentionally spread. It was better for me though, despite scientific data. Also, I would never purposely go out looking for morphine, due to the poor bioavailability, but these Kadians were given to me for free... and I am a weak and feeble ole soul when it comes to free drugs of any sort!! :D

[CIIORNOTHING]

I full-heartedly agree, CII. However, I personally don't want to pick up the needle just yet. I have many years of opiate addiction ahead of me, so I have to drag my feet as much as possible if I intend to reach a ripe ole opiated age.

Although, for me, the nasal spray was much better than oral or rectal administration, I corrected my original post to help snuff out mis-information that I had unintentionally spread. It was better for me though, despite scientific data. Also, I would never purposely go out looking for morphine, due to the poor bioavailability, but these Kadians were given to me for free... and I am a weak and feeble ole soul when it comes to free drugs of any sort!! :D


Oh trust me, I wouldnt turn em down either. My doc Rx's them to me, and my insurane covers em so I dont mind them myself. Luckily I have other avenues of better stuff to play with, but the kadians fill the void nicely when that stuff is out.

I hear ya on the needle. I recently came off it myself after getting really sick and scaring the shit out of myself and really saw myself going down a dark path FAST.


I have been just coasting on hydros the last week or so since I got sick, trying to figure out what I want to do. Its actually been easier than I thought. Ive been a lot more clear headed since I got off the daily MS and dilaudid thats for sure. Sex drive is coming back around.....I just might live the clean life for a while, who knows.

But hey, nice work on the nasal spray. I might try that with my Kadians are do soemthing really crazy and just swallow one :)