View Full Version : Grapefruit Juice?
Mild_Man
12-07-2005, 12:24 AM
Now I know that drinking this with hydrocodone and some other opiates can slow down the metabolism which you don't want. Since you want all the goodies to get into your system faster but what if I waited until effects were diminishing and drank it? Would this prolong the feelings or is there still metabolization of the hydrocodone into the goodies going on even when effects diminish?
~Thanks
Mokelly
12-07-2005, 12:31 AM
you are very confused man, drinking grapefruit juice doesn't prevent opiates from kicking in but potentiates the effects and enlongates the time in which it remains active in the body. the only exception is codeine. this topic has been discussed in great detail before, I'd do a search on it and read thoroughly.
duke_nemmerle
12-07-2005, 01:38 AM
I have found a swig of grapefruit juice when effects are diminishing to reinvigorate the effects. Then again, it wasn't major so this could be wholly placebo effect
Mokelly
12-07-2005, 03:39 AM
I have found a swig of grapefruit juice when effects are diminishing to reinvigorate the effects. Then again, it wasn't major so this could be wholly placebo effect
no you are right and I should have mentioned that before because mild man did also. It will indeed reinvigorate a buzz, but should be taken about a half hour before ingestion for maximum effect
Mild_Man
12-07-2005, 10:26 AM
no you are right and I should have mentioned that before because mild man did also. It will indeed reinvigorate a buzz, but should be taken about a half hour before ingestion for maximum effect
I've heard from different information that it shoudl not be taken with hydrocodone and codeine since it will slow the metabolism of codeine altogether which isn't good since you want the stuff in your system faster. Also, some hydrocodone I know basically goes directly to the brain but some doesn't so if you drink the juice beforehand I would think it would slow the metabolism of those goodies. It's just that you would have a more steady amount of hydrocodoen in your body for longer but I would think drinking beforehand would slow down the metabolism of parts of the hydrocodone. I've read across some forums and there are mixed opinions but I have seen alot who say it isn't good. Don't know if this post is too wordy but didn't knwo how else to write.
Mokelly
12-07-2005, 12:32 PM
whoever told you that is wrong!, for one hydrocodone is hydrocodone is hydrocodone! there is no such thing as a hydrocodone that does different things than another! yes grapefruit juice will inhibit the effects of codeine, CODEINE ONLY. I don't know where this guy is gettin his info but someone please back me up in helping him!
paesan
12-07-2005, 12:48 PM
I know for a fact that drinking grapefruit juice works with tea and M on it's own however I've never noticed much if any difference at all with the codones (hydro, oxy) and I know it doesn't work with codeine as codeine needs to metabolize (into m) in the liver in order to get you high.
As for the codones; I was under the impression that hydro converted in to hydromorphone and oxy into oxymorphone...would grapefruit juice hinder the metabolizm of these into the much stronger morphine derivatives??? And although hydro is a codeine derived opioid, oxy is not...it is a thebaine derived... and can be taken IV whereas codeine derived opioids cannot...so does oxy convert into oxymorphone at all, or am I a complete fucking idiot that has no idea what I'm talking about??? Man I'm fucking confused...
Mild_Man
12-07-2005, 01:01 PM
I know for a fact that drinking grapefruit juice works with tea and M on it's own however I've never noticed much if any difference at all with the codones (hydro, oxy) and I know it doesn't work with codeine as codeine needs to metabolize (into m) in the liver in order to get you high.
As for the codones; I was under the impression that hydro converted in to hydromorphone and oxy into oxymorphone...would grapefruit juice hinder the metabolizm of these into the much stronger morphine derivatives??? And although hydro is a codeine derived opioid, oxy is not...it is a thebaine derived... and can be taken IV whereas codeine derived opioids cannot...so does oxy convert into oxymorphone at all, or am I a complete fucking idiot that has no idea what I'm talking about??? Man I'm fucking confused...
Yeah, doesn't hydrocodone have to convert into hydromorphone in the liver. So using grapefruit juice beforehand would slow down this process and cause less of the goodies to be metabolized. I mean you'd probably still get a buzz but you wouldn't have as much goodies. I'm still confused if grapefruit juice goes well with hydrocodone, oxycodone, etc.
Mokelly
12-07-2005, 01:56 PM
it doesn't make as much of a difference as with m but it does work for ALL other opiates EXCEPT codeine, but if you feel it doesn't then just don't do it I guess , but there is a wealth knowledge on this topic on the web, just search! a great place to search and confirm all I have said would be the porg...
Mild_Man
12-07-2005, 01:59 PM
it doesn't make as much of a difference as with m but it does work for ALL other opiates EXCEPT codeine, but if you feel it doesn't then just don't do it I guess , but there is a wealth knowledge on this topic on the web, just search! a great place to search and confirm all I have said would be the porg...
Went to P.org but couldn't find any real confirming knowledge.
Mokelly
12-07-2005, 02:09 PM
seriously? come on mannnnn I'll go get a link for you
Mild_Man
12-07-2005, 02:13 PM
seriously? come on mannnnn I'll go get a link for you
:) Alright thanks... maybe I missed something but I did a search on the site.
Mokelly
12-07-2005, 02:15 PM
ok man just go to the porg, go to search, make sure you stretch the search date out to "any date" and type "potentiators" I really am dumbfounded that you said you couldn't find anything, there are like a hundred good links on the subject that I just found in literally ten seconds by using this method!
Mokelly
12-07-2005, 02:16 PM
sorry mild man I'm not trying to be mean
SomniGod
12-07-2005, 02:43 PM
To be truthfully honest, I have never noticed much of a difference in adding grapefruit juice to my opiates. I usually do drink some if I have it around merely to 'possibly' get more bang for the buck, but I really don't think that this is anything to argue over. i have an idea....test it ya self! I would:
1.) measure out 2 even doses of grounds.
2.) make tea out of dose #1.
3.) drink batch 1 (tea)
4.) enjoy it. write down when rush begins...intensity level...how long rush lasts...total duration.
5.) wait 2 days
6.) make tea out of dose #2.
7.) drink grapefruit juice 30 mins prior to drinking batch 2 (tea)
8.) enjoy it. write down when rush begins...intensity level...how long rush lasts...total duration.
9.) Analyze, compare, contrast results
10.) *MOST IMPORTANT* relay results to this org to help benefit others.
Not too difficult...many variations are possible... Sorry I can't do it myself... I am still working on "THE BEAST!"
~S~
duke_nemmerle
12-07-2005, 02:47 PM
Not too difficult...many variations are possible... Sorry I can't do it myself... I am still working on "THE BEAST!"
~S~
Hells yeah, good luck man. I can't wait :)
Mokelly
12-07-2005, 05:20 PM
hey duke what's up man? are you the new moderator of pharmaceuticals?
Mild_Man
12-07-2005, 06:44 PM
To be truthfully honest, I have never noticed much of a difference in adding grapefruit juice to my opiates. I usually do drink some if I have it around merely to 'possibly' get more bang for the buck, but I really don't think that this is anything to argue over. i have an idea....test it ya self! I would:
1.) measure out 2 even doses of grounds.
2.) make tea out of dose #1.
3.) drink batch 1 (tea)
4.) enjoy it. write down when rush begins...intensity level...how long rush lasts...total duration.
5.) wait 2 days
6.) make tea out of dose #2.
7.) drink grapefruit juice 30 mins prior to drinking batch 2 (tea)
8.) enjoy it. write down when rush begins...intensity level...how long rush lasts...total duration.
9.) Analyze, compare, contrast results
10.) *MOST IMPORTANT* relay results to this org to help benefit others.
Not too difficult...many variations are possible... Sorry I can't do it myself... I am still working on "THE BEAST!"
~S~
The Beast?? :eek:
Anyways, yeah I could do that but since I've never tried the tea my first time I would probably focus more on the effects and not really on analyzing anything. Maybe another time. Anyways I know it would probably work better with pods because the primary alkaloid present is morphine which isn't a pro-drug so doesn't need the liver for effects. With hydrocodone taking it priar to injestion would probably slow down metabolism from hydrocodone to hydromorphone and other things. I would do a test with hydro just for the hell of it but I have a very limited supply that I can't refill afterwards. :(
duke_nemmerle
12-07-2005, 11:56 PM
hey duke what's up man? are you the new moderator of pharmaceuticals?
hey bro, there's an announcement on the announce board. Yes, the rumors are true ;)
Mild_Man
12-08-2005, 05:22 PM
Btw, do you guys think a micron filter bag would help remove more of the APAP or is it kind of useless? I'm having a hard time finding one anywhere on ebay for a decent price.
Mokelly
12-08-2005, 09:28 PM
Unless you are going to be doing CWEs more than once a week I think it's useless man, just use common sense and find a material that is going to work well. Experiment!
Mild_Man
12-08-2005, 09:50 PM
Unless you are going to be doing CWEs more than once a week I think it's useless man, just use common sense and find a material that is going to work well. Experiment!
I'm still not sure exactly what cloth I should use in combination with a coffe filter or filters when extracting. I've heard the cloth should be more tightly woven than a regular shirt, so I guess like flannel maybe, I'm just not sure. Also, I don't want to ruin a perfectly good shirt, especially dress shirt. Also, that micron bag would probably be the most effective.
Mokelly
12-08-2005, 10:05 PM
man! holy shit you're taking this way too far lol! just experiment and use comon sense like I said, use a cloth that's woven a little tighter than a t shirt, hell it doesn't even matter since you're using a coffee filter for the second run through! you can use just about anything man it's not gonna be the end of the world if you don't get it 100% the first time! Just experiment and see what works best for you as you go along!!!!!!!!! AHHHHHHHHHHH you ask the same questions like a million times in a diffrent way! read the posts, research things! Use COMMON SENSE
Mild_Man
12-08-2005, 10:17 PM
man! holy shit you're taking this way too far lol! just experiment and use comon sense like I said, use a cloth that's woven a little tighter than a t shirt, hell it doesn't even matter since you're using a coffee filter for the second run through! you can use just about anything man it's not gonna be the end of the world if you don't get it 100% the first time! Just experiment and see what works best for you as you go along!!!!!!!!! AHHHHHHHHHHH you ask the same questions like a million times in a diffrent way! read the posts, research things! Use COMMON SENSE
:) Yeah, sorry 'bout that. I just want to get it down right this time otherwise I'll be disappointed and there will be no chance to try again to quelm that disappointment. I only have one more 15 pill, 10/500, reill left and then nothing ever so I have a very limited supply here. I wish I could get somehow hydros or oxies on a regular basis but that is not legally possible. Anyways, where do you get your hydros from?
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