best MOA for getting the most out of roxi 15's

[dirtmcgirt]

sniff, snort, or IV???? there seems to be an awful lot of powder to cook up or snort .... and when i used to IV OC's the high was very short lived

[moviebuff927]

sniff, snort, or IV???? there seems to be an awful lot of powder to cook up or snort .... and when i used to IV OC's the high was very short lived

Roxi's are considered by most people to be better to IV than OC because of the instant release and small amount of filler.

Best MOA??? Umm, in terms of EFFICIENCY, the MOA is always going to be IV. You waste little to none of the drug, and the drug is delivered STRAIGHT to your bloodstream, where you always want your drug to end up. When you snort a drug, you have to wait for it to be absorbed by your bloodstream before you feel it...when you take them by mouth you have to wait for the drug to be absorbed in your bloodstream...

See why IV is always going to be the most efficient way of administering a drug? It puts all of the drug immediately into the bloodstream. Bypasses all the other things like stomach and mucous membranes.

What am I recommending? That's a matter of personal taste. If you already IV, then the answer is obvious. But it's ultimately up to you.

[Synack]

IV half, snort the rest :p

[betmylife]

accually, oxy has 99% bio when taken orally....I ussually sniff half my dose, and eat the other half......the half you eat will make the high last at least 4 hours.....or if you wanna IV the first half.....but if you dont wanna get into IV then sniff half eat half.....thats best for oxy....not every drug.....morphine for example is wasted if you eat it, same with dilaudid....anyways, for roxi 15s I would eat one, and snort/shoot one....or whatever your dose is.........



BML

[moviebuff927]

accually, oxy has 99% bio when taken orally

Sorry, bml, I have to disagree with you here...the different formulations of oxycodone all differ slightly in their bioavailability...Roxicodone has an oral bioavailibility (compared to parentarel) of 60-87%...this is straight from the Roxicodone prescibing information from Xanodyne and easily accessed here on the internet or in your PDR if you have one.

Here's the link if you're interested:

http://www.xanodyne.com/products/pdf/Roxicodone%20Tablet%20Final%204-25-06%2010004436-01.pdf

[betmylife]

Sorry, bml, I have to disagree with you here...the different formulations of oxycodone all differ slightly in their bioavailability...Roxicodone has an oral bioavailibility (compared to parentarel) of 60-87%...this is straight from the Roxicodone prescibing information from Xanodyne and easily accessed here on the internet or in your PDR if you have one.

Here's the link if you're interested:

http://www.xanodyne.com/products/pdf/Roxicodone%20Tablet%20Final%204-25-06%2010004436-01.pdf



you didnt read the whole thing sir, not to correct you or anything but this reads from the website.......
Absorption: The relative oral bioavailability
of ROXICODONE® 15 mg and 30 mg tablets, compared
to the 5 mg ROXICODONE® tablets, is 96% and 101%
respectively.



if Im understanding it wrong, let me know.....I dunno, whenever I shot roxis, they didnt last too long.....my ROA is snorting them, but lately I have found eating them to work better....I have noticed some others on here say the same thing, Ike for example....anyways, maybe its diff for everyone, but if comparinf snorting to eating, eating is more effective I say...IV, I dunno, maybe technically its a faster admin, but what about the length of the drug?.....

[moviebuff927]

you didnt read the whole thing sir, not to correct you or anything but this reads from the website.......
Absorption: The relative oral bioavailability
of ROXICODONE® 15 mg and 30 mg tablets, compared
to the 5 mg ROXICODONE® tablets, is 96% and 101%
respectively.



if Im understanding it wrong, let me know.....I dunno, whenever I shot roxis, they didnt last too long.....my ROA is snorting them, but lately I have found eating them to work better....I have noticed some others on here say the same thing, Ike for example....anyways, maybe its diff for everyone, but if comparinf snorting to eating, eating is more effective I say...IV, I dunno, maybe technically its a faster admin, but what about the length of the drug?.....


Compared to the 5mg tablets, the 15mg and 30mg tablets have a bioavailability of 96% and 101%. That is COMPARED TO THE 5MG TABLETS. How can a pill be 101% if it's not being compared to another type of strength or ROA?

That's what that means.

[betmylife]

Compared to the 5mg tablets, the 15mg and 30mg tablets have a bioavailability of 96% and 101%. That is COMPARED TO THE 5MG TABLETS. How can a pill be 101% if it's not being compared to another type of strength or ROA?

That's what that means.


I dunno, I dont do the best research at 4:30 in the fucking morning......anyway you take the god damn thing its a fun drug.....maybe he should read the plugging thread.......Im going to sleep. sorry to be a moron MB.....later


BML (I was 101% wrong :()

[dirtmcgirt]

ive prepped the 30's before for IV without a problem, but these end up with alot of goop in the end.... i havent seen 30's in so long but these look like they are about the same size, so i get all this extra goop left over...

anyways im tired of sticking myself anyway..... but even crushed up.... they leave 2 pretty big ass lines... btw this is the "acta" generics

im thinking about just sniffing 30mg and eating the other 30mg when i do these from now on

i sure wish the doc would give me 30's and tell me to cut them in half.... yea right :)

[Opilover]

If you snort the vikes will they hit harder & faster or better just to eat them? Sorry I know this is off topic but figured we are on the subject of ROA..Thanks

[dirtmcgirt]

snorting vikes is a waste (or percs for that matter) cus your snorting so muchinactive matter (mostly tylenol) that any small amounty of the 10-30mg of whatever u snorted isnt going to be absorbed nasally due to all the filler cloggin up your nose....

thats why i asked about the roxi's.... there is about the same amount of filler and pill size with the 15's as there is with the 30's..... though maybe there was some other factor that made them seem less effective.

and shooting them??/ not unless you plan on using at least a 3cc rig..... your gonna need at least 1/2 to 1cc per pill when you prep it.... and you'll end up with not only the goopy qtip end which seems to not work so well and make yo ugo through a afew of them sometimes, but the shit left over i guess the talk and binder has a similaar consistancy.......

shooting these are def. a no no unlesss your an expert

[dirtmcgirt]

anyone ever get any noticed benefit from plugging oxy????? i know i get great results with 60-75mg of my fathers MS IR (i inherited the assholes bad back genetics..... the only reason i even tried this is cuz when i tried to shoot them, i could not filter all that talc out of them unless i ran it through a .45 or .22 micron filter/ forget which size..... but even then not being able to exercise right now or bodybuild my normallly rope like viens have dissapeared the last 2 years.....

and plugging the morphine Sulfate does the job.... i just wonder if u get any more of a rapid onset than snorting.... or any higher bioavailability than oral or nasal (i know the controversey about nasal Bio but i think as long as you flush your nose out after it is the same plus u get the quicker onset.

[dirtmcgirt]

now if i could only get my pain doc to give me dilly's like the last one did..... but i dont think that will be happening unless i get surgery.... and im not gonna get a 2 level spinal fusion at 29 just for some dillly's..... discectomy yes im ready for, but not fusion..... if anyone has a good spinal surgeon who doesnt think fusion is the be all end all of back surgeries please let me know cuz im desperate